1. Microtubules are primarily composed of which protein?

a. Vimentin
b. Tubulin
c. Acti
d. Keratin
e. Myosin

2. Which of the following structures is formed by microtubules?

a. Hemidesmosomes
b. Microvilli
c. Sarcomeres
d. Desmosomes
e. Cilia

3. Which cytoskeletal element is involved in the formation of the mitotic spindle?

a. Microtubules
b. Actin filaments
c. Desmin filaments
d. Intermediate filaments
e. Microfilaments

4. Which nucleotide is required for microtubule polymerization?

a. ADP
b. GTP
c. CTP
d. ATP
e. UTP

5. Which cytoskeletal element is involved in the formation of microvilli?

a. Microfilaments
b. Desmin filaments
c. Intermediate filaments
d. Lamin filaments

6. What happens to a microtubule when it loses its GTP cap?

a. It becomes rigid
b. It forms a new cap

c. It depolymerizes

d. It stabilizes
e. It elongates
 7. Intermediate filaments are primarily involved in:
a. Cell motility
b. Cell division
c. Intracellular transport
d. Chromosome movement
e. Providing mechanical support

8. The cytoskeleton includes all of the following except

a. microtubules
b. actin filaments

c. myosin filaments
d. intermediate filaments

9. Which class of intermediate filaments is not associated with the suggested location?
a. Keratin - Location: epithelial cells, hair, nails
b. Neurofilaments - Location: axons of neurons

c. Nuclear lamins - Location: outer nuclear membrane

d. Nestin - Location: stem cells of the CNS

10. Which of the following statements about actin filament polarity is correct?

a. Both ends have equal rates of polymerization

b. The pointed end is more dynamic and undergoes rapid polymerization
c. The barbed end is more dynamic and undergoes rapid polymerization
d. The barbed end is the site of ATP hydrolysis
e. The pointed end is the site of rapid growth

11. Which of the following is NOT a function of microfilaments?

a. cytoplasmic streaming
b. chromosome separation
c. endocytosis in cells
d. cell adhesion

12. Which cytoskeletal element is known for its role in muscle contraction?
Desmin filaments
Lamin filaments
Microfilaments
Intermediate filaments
Microtubules

13. Which end of a microtubule is associated with rapid growth?

a. Middle region
b. Neither end grows
c. Minus end
d. Both ends grow equally
e. Plus end

14. Which type of cytoskeletal filament do desmosomes connect to?

a. Lamin filaments
b. Actin filaments
c. Microtubules
d. Myosin filaments
e. Intermediate filaments

15. What is the primary function of the pointed end of a microfilament?

a. Stabilization
b. Rapid polymerization
c. Slow depolymerization
d. Slow polymerization
e. Rapid depolymerization

16. The cytoskeleton includes all of the following except

a. myosin filaments
b. intermediate filaments
c. microtubules

d. actin filaments

17. Which of the following statements about intermediate filament polymerization is true?
a. It does not require nucleotide hydrolysis
b. It requires ATP hydrolysis
c. It requires GTP hydrolysis

d. It requires calcium ions

e. It requires phosphorylation

18. What is the structural arrangement of tubulin in a microtubule?

a. Double helix
b. Hollow tube of 13 protofilaments
c. Triple helix

d. Single helical strand

e. Flat sheet of protofilaments

19. Which complex mediates the connection between the cytoskeleton and the nucleoskeleton?
a. Tight junction complex
b. Desmosome complex
c. Integrin complex
d. Cadherin complex
e. LINC complex

20. Which cytoskeletal element is primarily involved in adherens junctions?

a. Intermediate filaments
b. Desmin filaments
c. Lamin filaments
d. Microtubules

e. Actin filaments

21. Which end of a microfilament is referred to as the barbed end?

a. Lateral sides
b. Minus end
c. Plus end
d. Middle region
e. Both ends

22. Microfilaments exhibit polarity with distinct ends. Which end is more favorable for actin
polymerization?
a. Minus end
b. Lateral sides
c. Both ends equally
d. Neither end
e. Plus end

23. Which one of the following statements is TRUE about intermediate filaments?
a. They consist of two proto-filaments that form a left-handed helix.
b. They provide intracellular mechanical support and tensile strength.
c. They associate with motor proteins via their motor domain.
d. They are responsible for cyclosis in plant cells.

24. Which one of the following statements does NOT describe an intermediate filaments:
a. They are found in the nucleus under the cell membrane.
b. They are the most dynamic cytoskeletal element.

c. They are tension bearing cytoskeletal elements.

d. They are 6 major classes have been shown to exist in cells.

25. Which of the following is the primary protein component of microfilaments?

a. Keratin
b. Tubulin
c. F-Actin
d. G-Actin
e. Lamin

1. Which of the following is TRUE about intermediate filaments?

They associate with motor proteins via their motor domain.
They bind to endosomes and move them towards the ER.
They provide intracellular mechanical support and tensile strength.
They consist of two proto-filaments that form a left-handed helix.
They are responsible for cyclosis in plant cells.

2. Which type of junction involves a connection to the actin

cytoskeleton?
adherens junctions
desmosomes
tight junctions
gap junctions

3. Which of the following is NOT a function of microfilaments?

Muscle contraction
Chromosome movement
Maintaining cell shape
Cytoplasmic streaming
Cell motility

4. Microfilaments exhibit polarity with distinct ends. Which end is more favorable for actin
polymerization?
Plus end
Neither end
Minus end
Both ends equally
Lateral sides

5. Which cytoskeletal element is primarily involved in adherens junctions?

Actin filaments
Intermediate filaments
Desmin filaments
Lamin filaments
Microtubules

6. Which complex mediates the connection between the cytoskeleton and the nucleoskeleton?
Cadherin complex
Integrin complex
Tight junction complex
Desmosome complex
LINC complex

7. Which protein links actin filaments to the plasma membrane?

Question 7Answer
a.
Vimentin
b.
Spectrin
c.
Tubulin
d.
Keratin
e.
Lamin
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Question 8
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Which type of cytoskeletal filament do desmosomes connect to?
Question 8Answer
a.
Intermediate filaments
b.
Actin filaments
c.
Microtubules
d.
Myosin filaments
e.
Lamin filaments
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Question 9
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Intermediate filaments are primarily involved in:
Question 9Answer
a.
Cell motility
b.
Chromosome movement
c.
Providing mechanical support
d.
Intracellular transport
e.
Cell division
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Question 10
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The cytoskeleton includes all of the following except
Question 10Select one:
a.
myosin filaments
b.
actin filaments
c.
intermediate filaments
d.
microtubules
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Question 11
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The cytoskeleton provides tension bearing support within and between cells by tethering themselves to:
Question 11Answer
a.
anchoring junctions
b.
occluding junctions
c.
septate junctions
d.
gap junctions
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Question 12
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What is the primary function of the pointed end of a microfilament?
Question 12Answer
a.
Stabilization
b.
Slow depolymerization
c.
Rapid polymerization
d.
Slow polymerization
e.
Rapid depolymerization
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Which end of a microfilament is referred to as the barbed end?
Question 13Answer
a.
Minus end
b.
Middle region
c.
Both ends
d.
Plus end
e.
Lateral sides
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Question 14
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Nuclear lamins are:
Question 14Answer
a.
Intermediate filaments
b.
Microtubules
c.
Spectrins
d.
F-actin homologs
e.
G-actin monomers
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Question 15
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Which of the following statements about intermediate filament polymerization is true?
Question 15Answer
a.
It requires calcium ions
b.
It requires phosphorylation
c.
It requires ATP hydrolysis
d.
It does not require nucleotide hydrolysis
e.
It requires GTP hydrolysis
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Question 16
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Which of the following statements about actin filament polarity is correct?
Question 16Answer
a.
The pointed end is the site of rapid growth
b.
The barbed end is more dynamic and undergoes rapid polymerization
c.
The pointed end is more dynamic and undergoes rapid polymerization
d.
Both ends have equal rates of polymerization
e.
The barbed end is the site of ATP hydrolysis
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Question 17
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Which of these is NOT a function of microfilaments:
Question 17Answer
a.
Formation of contractile ring during cytokinesis in plant cells.
b.
Separation of chromosomes during cell division.
c.
Linking of transmembrane proteins to cytoplasmic proteins to cell junctions.
d.
The formation of endocytotic vesicles in white blood cells.
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Question 18
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What happens to a microtubule when it loses its GTP cap?
Question 18Answer
a.
It stabilizes
b.
It elongates
c.
It depolymerizes
d.
It forms a new cap
e.
It becomes rigid
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Question 19
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The cytoskeleton includes all of the following except
Question 19Answer
a.
intermediate filaments
b.
actin filaments
c.
microtubules
d.
myosin filaments
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Question 20
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Which nucleotide is required for microtubule polymerization?
Question 20Answer
a.
CTP
b.
GTP
c.
ATP
d.
ADP
e.
UTP
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Question 21
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Which protein monomer is necessary for the synthesis of microtubules?
Question 21Answer
a.
tubulin
b.
G-actin
c.
F-actin
d.
Myosin
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Question 22
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Which of the following is NOT a function of microfilaments?
Question 22Answer
a.
chromosome separation
b.
endocytosis in cells
c.
cytoplasmic streaming
d.
cell adhesion
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Question 23
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Which one of the following statements does NOT describe an intermediate filaments:
Question 23Answer
a.
They are the most dynamic cytoskeletal element.
b.
They are found in the nucleus under the cell membrane.
c.
They are 6 major classes have been shown to exist in cells.
d.
They are tension bearing cytoskeletal elements.
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Question 24
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Which cytoskeletal element and motor protein allows the contraction of muscles?
Question 24Answer
a.
Microtubules and myosin
b.
Microfilaments and myosin
c.
Actin filaments and dyenein
d.
Intermediate filaments and kinesin
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Question 25
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During actin polymerization, which end of the microfilament grows faster?
Question 25Answer
a.
Middle region
b.
Both ends grow equally
c.
Neither end grows
d.
Plus end
e.
Minus end
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