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    Bugs and Drugs Cheat Sheet April 2021

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    Zohaib Maqbool
    Bugs-and-Drugs-Cheat-Sheet-April-2021

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    Bugs and Drugs Cheat Sheet April 2021

    Uploaded by

    Zohaib Maqbool
    47 views1 page
    Bugs-and-Drugs-Cheat-Sheet-April-2021

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    Bugs-and-Drugs-Cheat-Sheet-April-2021

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    Bugs-and-Drugs-Cheat-Sheet-April-2021

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    47 views1 page

    Bugs and Drugs Cheat Sheet April 2021

    Uploaded by

    Zohaib Maqbool
    Bugs-and-Drugs-Cheat-Sheet-April-2021

    Copyright:

    © All Rights Reserved
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    of 1

    Bugs & Drugs Study Cheat Sheet

    When You See… Consider Using…


    GRAM POSITIVES
    Oral: cephalexin, cefadroxil, amox/clav;
    MSSA
    IV: cefazolin, oxacillin, nafcillin
    Oral: SMX/TMP, doxycycline, clindamycin, linezolid,
    tedizolid, omadacycline, delafloxacin; IV: vancomycin,
    MRSA daptomycin, telavancin, dalbavancin, oritavancin, ceftaroline,
    tigecycline, eravacycline; all oral options also come as IV
    Ampicillin, then vancomycin; if VRE: linezolid, daptomycin,
    Enterococci oritavancin, tigecycline, omadacycline, eravacycline,
    nitrofurantoin (UTI only), Fosfomycin (UTI only)
    Strep. pyogenes or
    Penicillin, amoxicillin, clindamycin
    Strep. agalactiae
    Ceftriaxone, levofloxacin, amoxicillin, amoxicillin-
    Strep. pneumoniae or
    clavulanic acid (⚠ beware penicillin & macrolide
    Viridans group Streptococci
    resistance)
    Listeria monocytogenes Ampicillin
    GRAM NEGATIVES
    Oral: ciprofloxacin, levofloxacin, delafloxacin;
    IV: pip/taz, ceftazidime, ceftazidime-avibactam,
    Pseudomonas aeruginosa cefepime, ceftolozane-tazobactam, cefiderocol,
    imipenem-cilastatin +/- relebactam, meropenem,
    aztreonam, aminoglycosides, polymyxins
    Oral: cephalexin, amoxicillin-clavulanic acid,
    SMX/TMP, nitrofurantoin (cystitis only), fosfomycin,
    E. coli, Klebsiella ciprofloxacin, levofloxacin, delafloxacin
    IV: ceftriaxone, ampicillin-sulbactam (⚠ resistance),
    cefepime, piperacillin-tazobactam, carbapenems
    Carbapenems, ceftolozane-tazobactam, ceftazidime-
    avibactam, meropenem-vaborbactam, imipenem-
    ESBL-producer /
    cilastatin-relebactam, cefiderocol, polymyxins,
    Drug-Resistant GNR
    aminoglycosides, fosfomycin, nitrofurantoin (cystitis only),
    tigecycline, omadacycline, eravacycline
    Carbapenem resistant GNR ESBL-producer drug list minus carbapenem alone
    NDM producer Aztreonam + (MERO/VAB or CAZ/AVI)
    Stenotrophomonas SMX/TMP, levofloxacin, minocycline
    Salmonella typhi Fluoroquinolone, SMX/TMP, ceftriaxone
    FUNGI
    Candida albicans Fluconazole
    Candida glabrata Echinocandin, but can use fluconazole if susceptible
    Candida krusei Micafungin, anidulafungin, or caspofungin
    Candida auris Micafungin, anidulafungin, or caspofungin
    Aspergillus Voriconazole
    VIRUSES
    Cytomegalovirus (CMV) Valganciclovir, letermovir, ganciclovir, foscarnet
    Herpes Simplex Virus (HSV) PO: acyclovir, famciclovir, valacyclovir; IV: acyclovir
    Varicella Zoster Virus (VZV) Valacyclovir (PO), famciclovir (PO), acyclovir (IV/PO)
    Influenza PO: oseltamivir, baloxavir marboxil; IV: peramivir
    SARS-CoV-2 (COVID-19) Remdesivir; monoclonal antibodies
    MISCELLANEOUS
    Oral: metronidazole, clindamycin, amoxicillin-
    clavulanic acid, moxifloxacin
    Anaerobes
    IV: ampicillin-sulbactam, piperacillin-tazobactam,
    cefoxitin, cefotetan, ertapenem, tigecycline
    Clostridioides difficile Oral vancomycin or fidaxomicin
    (formerly Clostridium difficile) ! Metronidazole no longer preferred
    Atypical organisms Macrolides, fluoroquinolones, tetracyclines, lefamulin
    Cryptosporidium parvum Nitazoxanide
    Cystoisospora sp. (Isospora) SMX/TMP
    Leishmania sp. Amphotericin B
    Borrelia burgdorferi (Lyme dz) Doxycycline
    Treponema pallidum (Syphilis) Penicillin
    Rifampin + isoniazid + pyrazinamide + pyridoxine
    Mycobacterium tuberculosis
    + ethambutol – “RIPPE”
    Mycobacterium avium (MAC) Clarithromycin+ ethambutol (tx), azithromycin (px)
    Pneumocystis Pneumonia (PCP) SMX/TMP (tx or px)
    Toxoplasma gondii Pyrimethamine +sulfadiazine +leucovorin (tx); SMX/TMP (px)

    ABBREVIATIONS: Amox/clav = amoxicillin/clavulanic acid, CAZ/AVI = ceftazidime/avibactam, ESBL = extended-spectrum beta-lactamase, GNR = Gram negative
    rod, IV = intravenous, MERO/VAB = meropenem/vaborbactam, MRSA = methicillin-resistant S. aureus, MSSA =methicillin-susceptible S. aureus, NDM = New Delhi
    metallo-beta-lactamase, PIP/TAZ = piperacillin/tazobactam, PO = oral, SMX/TMP = sulfamethoxazole/trimethoprim, VRE = vancomycin resistant Enterococci

    Last updated April 2021 www.LearnAntibiotics.com

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