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    AMOXICILLIN Drug Study 1

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    Shamelle Tobias

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    AMOXICILLIN Drug Study 1

    Uploaded by

    Shamelle Tobias
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    9 views11 pages

    AMOXICILLIN Drug Study 1

    Uploaded by

    Shamelle Tobias

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
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    WESLEYAN UNIVERSITY - PHILIPPINES

    COLLEGE OF NURSING

    AMOXICILLIN
    TOBIAS, SHAMELLE B.
    BSN 2-1
    Pharmacological Properties:
    Bactericidal action
    Broad spectrum of activity
    Inhibits bacterial cell wall synthesis
    Well-absorbed after oral administration
    Similar activity to penicillin and ampicillin
    FDA-approved since 1974
    INDICATIONS:
    Treats susceptible bacterial infections of:
    Ear, nose, throat Combined with clavulanic acid for:
    Genitourinary tract Acute bacterial sinusitis
    Skin, skin structure Community-acquired pneumonia
    Lower respiratory tract Acute bacterial otitis media
    Urinary tract infections
    CONTRAINDICATIONS:
    Hypersensitivity or history of severe allergic
    reactions to amoxicillin or other beta-lactams
    Suspected or confirmed infectious mononucleosis
    Liver Disease
    Kidney Disease
    History of Gastrointestinal Disease
    History of Bleeding Disorders
    SIDE EFFECTS:
    Nausea, vomiting, or diarrhea may occur.
    Prolonged use may lead to oral thrush or vaginal yeast infection.
    Serious side effects may include signs of liver disease or easy
    bruising/bleeding.
    Rarely, it can cause a severe intestinal condition called
    C. difficile infection.
    Mild rash is common but monitor for signs of a severe
    allergic reaction
    INTERACTIONS:
    Methotrexate: could potentially altering the effectiveness or
    safety of either medication.
    Oral Anticoagulants: May cause abnormal prolongation of
    prothrombin time (INR); monitor closely.
    Allopurinol: Increases risk of rashes when used with amoxicillin.
    Probenecid: Reduces renal tubular secretion of amoxicillin,
    leading to increased and prolonged blood levels.
    DOSAGE AND ADMINISTRATION:
    Adult Dosage:
    750 to 1750 mg/day
    Divided doses every 12 hours : @12mn, 12nn
    Pediatric Dosage (Over 3 Months):
    20 to 45 mg/kg/day
    Divided doses every 8 hours: @12mn, 8am, 4pm
    Neonates and Infants (3 Months or Younger):
    Maximum dose: 30 mg/kg/day
    Divided doses every 12 hours: @12mn, 12nn
    NURSING CONSIDERATIONS INTERVENTIONS
    BEFORE ADMINISTRATION:
    Follow the 10 rights of drug administration to ensure safe patient care.
    Assess the patient’s vital signs prior to administration.
    Assess allergy history before treatment.
    Periodically monitor renal, hepatic, and hematologic functions.
    Monitor electrolyte balance.
    Monitor for signs of anaphylaxis, skin rash, and antibiotic-associated diarrhea.
    Instruct the patient about the possible side effects and report immediately.
    NURSING CONSIDERATIONS INTERVENTIONS
    AFTER ADMINISTRATION:
    Monitor for therapeutic effectiveness: response to the medication.
    Monitor for Adverse Reactions such as rash, itching, swelling, or difficulty
    breathing.
    Evaluate for Superinfection such as oral thrush or vaginal yeast infection.
    Emphasize the importance of finishing the prescribed course of
    amoxicillin, even if symptoms improve.
    Encourage patients to report any new or worsening symptoms promptly.
    WESLEYAN UNIVERSITY - PHILIPPINES
    COLLEGE OF NURSING

    drug’s pharmacological properties- Amoxicillin. Amoxicillin - an overview |


    ScienceDirect Topics. (n.d.).
    Amoxicillin. Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.).
    https://go.drugbank.com/drugs/DB01060
    Amoxicillin: Package insert. Drugs.com. (n.d.).
    Team, C. by Mimso. (n.d.). Amoxicillin. Amoxicillin: Indication, Dosage, Side
    Effect, Precaution | MIMS Philippines.
    WebMD. (n.d.). Amoxicillin oral: Uses, side effects, interactions, pictures,
    warnings & dosing. WebMD.
    Amoxicillin: Package insert. Drugs.com. (n.d.).
    WESLEYAN UNIVERSITY - PHILIPPINES
    COLLEGE OF NURSING

    TOBIAS, SHAMELLE B.
    BSN 2-1

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