Khan Agar 2020
Khan Agar 2020
Khan Agar 2020
Legal Medicine
journal homepage: www.elsevier.com/locate/legalmed
A R T I C L E I N F O A B S T R A C T
Keywords: Forensic odontology (FO) mainly deals with the identification of the individual through the remains, which
Artificial intelligence mainly includes teeth and jawbones. Artificial intelligence (AI) technology has proven to be a breakthrough in
Artificial neural networks providing reliable information in decision making in forensic sciences. This systematic review aimed to report on
Convolutional neural networks
the application and performance of AI technology in FO. The data was gathered through searching for the articles
Deep learning
Forensic odontology
in the renowned search engines, which have been published between January 2000 - June 2020. QUADAS-2 was
Forensic dentistry adopted for the risk of bias analysis of the included studies. AI technology has been widely applied in FO for
Machine learning identifying bite-marks, predicting mandibular morphology, gender determination, and age estimation. Most of
these AI models are based on either artificial neural networks (ANNs) or convolutional neural networks (CNNs).
The results of the studies are promising. Studies have reported that these models display accuracy and precision
equivalent to that of the trained examiners. These models can be promising tools when identifying victims of
mass disasters and as an additive aid in medico-legal situations.
* Corresponding author at: Preventive Dental Science Department, College of Dentistry, King Saud Bin Abdulaziz University for Health Sciences, King Abdullah
International Medical Research Center, Ministry of National Guard Heath Affairs, Riyadh, Saudi Arabia.
E-mail address: [email protected] (S.B. Khanagar).
https://doi.org/10.1016/j.legalmed.2020.101826
Received 29 August 2020; Received in revised form 19 November 2020; Accepted 4 December 2020
Available online 10 December 2020
1344-6223/© 2020 Elsevier B.V. All rights reserved.
S.B. Khanagar et al. Legal Medicine 48 (2021) 101826
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S.B. Khanagar et al. Legal Medicine 48 (2021) 101826
Identification
Records identified through database Additional records identified through
searching other sources
(n = 718) (n = 9)
eligibility
(n = 459) exclusion criteria
(n = 450)
the authors)
Studies included in
qualitative synthesis
(n = 8)
A total of 8 research articles were analyzed for quantitative data. The The studies that were included in this review were mainly on the
analysis of the literature showed that the majority of the studies were application of AI in FO for identifying bite-marks [28] predicting the
conducted in the past 10 years. mandibular morphology [29] gender determination [2,30] and age
estimation [23,31,32] (Fig. 2).
Most of these AI-based studies have used artificial neural networks
(ANNs) [2,28,30] and convolutional neural networks (CNNs)
Age estimation
Gender determination
Identifying bitemarks
3
S.B. Khanagar et al. Legal Medicine 48 (2021) 101826
[23,31,32]. A study reported of using Bayesian convolutional neural authors also state that the application of this study may not be used to
networks (BCNNs) [33]. These neural networks were designed to assess identify the crime at this stage.
panoramic radiographs (OPG), digital photographs, cephalometric ra
diographs, lateral cephalometric radiographs (Table 2). 4.2. Mandibular morphology and artificial intelligence
3.2. Risk of bias assessment and applicability concerns Predicting the mandibular morphology is a very crucial aspect of
forensic sciences, especially when there is a need to reconstruct the face
The risk of bias assessment was carried out using the QUADAS-2 tool of the victim with a loss of mandibular bone. This becomes an important
for diagnostic tests. In the risk of bias arm of the tool, 75% of the studies aspect of the identification of an individual through their mortal re
reported low risk for the patient section. One study each reported high mains, especially during mass disasters. Mandibular prediction can be a
risk [28] and unclear risk [30] (Supplementary Table 1). Since the data very important tool in improvising the facial reconstruction. Sandoval
feeding in AI technology is highly standardized, and there is no effect of et al. [29] reported using an AI-based model for predicting the
flow and time frame in the final output, both the aspects were regarded mandibular morphology through craniomaxillary variables on lateral
as low-risk categories in all the studies. The included studies were based radiographs in patients with skeletal class I, II and III, using automated
on the age estimation and sex determination, which does not require any learning techniques, such as Artificial Neural Networks and Support
gold standard preference test for determination. Hence, reference stan Vector Regression The results of the study were quite promising. The
dards in all the studies were reported as low risk, except for the study by ANN model demonstrated high predictability ability, and this model
Stern et al. [31] where unclear risk was identified. Following the risk of could play a key role in facial reconstruction. These results were like the
bias arm of a QUADAS-2 assessment tool, the applicability concern arm results of another study, which showed similar accuracy in predicting
also showed similar results (Supplementary Table 2) (Fig. 3a and b). the mandibular morphology [37,38].
FO mainly deals with the identification of the victims of mass di Gender determination is of prime importance when identifying an
sasters, where a visual identification alone is reported to have high er individual during mass disasters, during accidental remains and medico-
rors [34]. Forensic odontologist deals with the dental remains of the legal cases. Skeletal bones are one of the strongest bones of the human
victims and matches them with the dental records of the missing person body, and they play a vital role in identifying the individual’s gender
[35] most times these are of very much importance in estimating the age [22,39,40].
of the victims [36]. Gender identification and age estimation are of Human teeth which are the part of the human skull can be measured
major concerns when recognizing a victim of such disasters, and also for in both living and also in the remains of the deceased individuals.
estimating the chronological age of an undocumented individual. In the permanent dentition, there is a difference in the genders,
AI is a technological advancement which has been widely used in mainly because of hormonal changes, which affect the size and shape of
forensic medicine. It has proven to be very efficient in estimating the teeth [41]. Canine teeth are known for demonstrating the highest degree
biological age and predicting the gender of the living and the diseased. of sexual dimorphism in humans. It is also a known fact that canine teeth
Despite limited number confirmative studies, it is has been stated as the are least affected teeth with dental caries and periodontal diseases
use of AI in forensic medicine is progressing beyond conventional henceforth are retained for longer when compared to any other teeth in
practice [18].This could be attributed to the automated technology with the oral cavity [42].
minimum errors in identifying the unknown patterns [19]. A study conducted by Fidya et al.[30]reported on a relatively new AI-
In this systematic review, we have analyzed the studies that have based technology for identifying sexual dimorphism in canines. In this
used AI-based models in forensic odontology. The chief advantage of study the authors quantified the respective accuracy of the Naive Bayes,
using the AI-based modes are, they are designed to identify an individual decision tree, and multi-layer perceptron methods in identifying sexual
through dental records, oral radiographs, and dental casts. These AI- dimorphism in canines the artificial intelligence methods produced a
based models are mainly designed and developed to overcome the highly accurate identification process relating to the gender determi
variability in allocation caused by the human eye and mind [23]. nation of canine teeth. The most appropriate method was the multi-layer
perceptron with a higher accuracy rate.
4.1. Bite mark and artificial intelligence Another study conducted by Patil et al. [2] reported on the appli
cation of an AI-based model for gender determination. This model was
Bite marks are considered as crucial evidence during sexual assaults/ highly accurate in identifying the gender of an individual using pano
attacks, sexual homicide, rape, and sexual abuse and also in child abuse. ramic radiographs. This model was compared with two standard gender
Analyzing human bite marks is very much challenging for forensic determination methods discriminant analysis and logistic regression
odontology. A study reported by Mahasantipiya et al. [28] reported on which have often showed excellent results in gender determination.
using artificial neural networks for bite mark identification. This was These two techniques were analyzed along with artificial neural net
mainly designed to develop a model with high accuracy in performance works. But the outcome of the study results substantiated that the AI
and to overcome human bias during the process of human identification. model was better than the other two models.
This model was trained by selecting some specific features of the bite
marks, following which the trained networks gave a reasonable result 4.4. Age estimation and artificial intelligence
for the matching accuracy in this initial study. Even though the neural
network used for the bite mark identification did not show a high level of Age estimation is mainly required for estimating the chronological
accuracy, it shows that this approach has potential and needs further age of an individual, for medico-legal issues, especially when there is a
study to improve the performance. Application and training with new legal confirmation required [43]. The age estimation of an individual is
features might be needed to improve the performance of this model. The mainly carried out by experts using hand-wrist radiographs and with the
4
S.B. Khanagar et al.
Table 2
Details of the studies that have reported on AI based models used in forensic odontology for personal identification, age estimation, and gender determination.
Serial Authors Year of Algorithm Objective of the No. of No. of Study factor Modality Evaluation Comparison if Results (+) Outcomes Authors suggestions/
no publication Architecture study images/ images/ accuracy /average any effective, recommendations
photographs photographs accuracy (-) non
for training / for testing effective
validating (N) neutral
1 Mahasantipiya 2011 ANNs Applying the 250 100 Bite marks Digital photographs Average accuracy Not (+) The experimental More studies are
et al28 neural network 82% Mentioned Effective results show needed to improve
approach in bite reasonable level the bite mark
mark of accuracy. identification
identification. accuracy
2 Fidya et al30 2017 ANNs Naive Bayes, 100 50 Upper and Teeth measurements The accuracy of Naive Bayes, (+) The MLP method The use of AI methods
decision tree, and lower MLP method was Decision tree Effective had a highest produced a highly
multi-layer canine 84%. accuracy and an accurate
perceptron (MLP) absolute error identification process
methods in value lower than relating to the gender
identifying sexual that of its determination of
dimorphism in decision tree canine teeth
canines counterpart.
3 Tobel et al23 2017 CNNs An automated 160 40 Tooth Panoramic Mean ICC was 2 observers (+) Deep CNN based Further optimization
technique for radiographs (OPG) 0.95 Effective AI system is required to achieve
staging the demonstrated a fully automated
development of similar results to system for estimating
lower third molar. the results the dental age.
demonstrated by
other trained
examiners.
4 Sandoval et al29 2017 ANNs AI based model for Not clear 229 Anatomical Lateral Coefficients from Support vector (+) This model This model may be
5
predicting the landmarks cephalograms 0.84 until 0.99 regression Effective demonstrated the key for facial
mandibular high reconstruction
morphology predictability
ability
5 Stern et al31 2017 CNNs Automatic multi- Not clear Not clear Skeletal Skeletal and Dental 1.14 \ pm 0.96 Radiologist (+) Improvement in None
factorial age structures MRI years of mean Effective sensitivity of the
estimation absolute error multi-factorial
methods based on system
MRI data
6 Back et al33 2019 BCNNs Bayesian 2400 Not clear Upper and Orthopantomograms Concordance Not (+) This model Initial results are
convolutional lower jaws Correlation Mentioned Effective provides encouraging although
neural networks to Coefficient ccc = quantitative the accuracy is not yet
perform age and 0:91 estimation of at the level that
uncertainty prediction warrants routine
estimation uncertainty, application.
which is
imperative within
a legal context.
7 Patil et al2 2020 ANNs ANN for gender 444 95 Mandible Panoramic Accuracy of 75% 1 experienced (+) ANN proved as a This automated
ANNs = Artificial Neural Networks, CNNs = Convolutional Neural Networks, BCNNs = Bayesian Convolutional Neural Networks, ROC = Receiver Operating Characteristic curve, AUC = Area Under the Curve, ICC =
chronological age of a
developing dentitions
Authors suggestions/
opinions need to be very precise in this task. To have a more precise and
especially in young
subject accurately,
recommendations
standard tool for estimating the chronological age of an individual,
several AI-based automated systems have been developed to overcome
subjects with
predict the
the observer subjectivity [45,46].
A study conducted by Tobel et al. [23] reported of applying an AI-
based model for staging the development of lower third molar on
panoramic radiographs. The performance was evaluated in a 5-fold
DASNet in every
cross-validation scenario, using different validation metrics like accu
racy, Rank-N recognition rate, mean absolute difference, linear kappa
Results (+) Outcomes
aspect
outperformed all other tested approaches. The model was efficient, and
when compared with the trained examiners, it displayed equivalent
(N) neutral
accuracy.
effective,
effective
(-) non
These results were similar to the study conducted by Stern et al. [31]
where the authors reported of using automatic multi-factorial age esti
mation methods based on MRI data to extend the maximal age range
Comparison if
Blanco et al. [32] in his study reported using two fully automatic
accuracy /average
respectively).
Network (CNN) path to predict the age, while the second (DASNet) adds
accuracy
a second CNN path to predict the sex and uses sex specific features with
the aim of improving the age prediction performance. The results
showed that the DASNet outperformed the DANet in every aspect.
DASNet can automatically predict the chronological age of a subject
accurately, especially in young subjects with developing dentitions.
These results were like the results of the study conducted by Back et al.
Modality
results are quite encouraging, although the accuracy is not yet at the
level that warrants routine application.
important role in various aspects of FO. However, all the studies pub
lished to date, and included in the present analysis were conducted on
for training /
experimental models, and hence, it cannot give the actual measure of the
photographs
validating
per our analysis, it has come to our notice that only certain subdivisions
chronological age
of a subject from
(Dental Age and
Objective of the
determination [2,30] and age estimation [23,31,32] have been used for
testing AI. Although it covers almost every aspect of FO, other aspects
study
parameters.
5. Conclusions
Year of
AI technology has been widely used in FO, and the results are
promising. Studies have reported that these models display accuracy and
precision equivalent to that of trained examiners. These models have an
added advantage of overcoming human errors and being non-invasive.
Table 2 (continued )
automated models have shown excellent results along with the elimi
nation of the human bias. These models can be promising tools when
identifying victims of mass disasters and as an additive aid in medico-
Serial
6
S.B. Khanagar et al. Legal Medicine 48 (2021) 101826
QUADAS-2 Domain
Fig. 3. Assessment of individual risk of bias domains and concerns regarding applicability. Foot note: In Fig. 3b there is no “flow and timing” variable on Y-axis.
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