Penilaian Framingham Statin Syamsul Bahri
Penilaian Framingham Statin Syamsul Bahri
Penilaian Framingham Statin Syamsul Bahri
Risk Factor Risk Points Points Total Points 10-Year CVD Risk (%)*
Heart Age, y Men Women
Men Women
Men Women -3 or less <1 <1 <30 <0 <1
Age -2 1.1 <1 30 0
-1 1.4 1.0 31 1
30-34 0 0 0 1.6 1.2 32 1
35-39 2 2 1 1.9 1.5 34 2 2
2 2.3 1.7 36 3 3
40-44 5 4 3 2.8 2.0 38 4
45-49 7 5 4 3.3 2.4 39 4
50-54 8 7 5 3.9 2.8 40 5
6 4.7 3.3 42 6 5
55-59 10 8 7 5.6 3.9 45 7 6
60-64 11 9 8 6.7 4.5 48 8 7
9 7.9 5.3 51 9 8
65-69 12 10 10 9.4 6.3 54 10
70-74 14 11 11 11.2 7.3 55 9
12 13.3 8.6 57 11
75+ 15 12 13 15.6 10.0 59 10
HDL-C (mmol/L) 14 18.4 11.7 60 12
15 21.6 13.7 64 13 11
>1.6 -2 -2 16 25.3 15.9 68 14 12
1.3-1.6 -1 -1 17 29.4 18.51 72 15
18 >30 21.5 73 13
1.2-1.29 0 0 19 >30 24.8 76 16
0.9-1.19 1 1 20 >30 27.5 79 14
21+ >30 >30 >80 ≥17 15+
<0.9 2 2
* Double cardiovascular disease risk percentage for individuals between the ages of 30 and 59 without diabetes if the presence of a positive history
Total Cholesterol of premature cardiovascular disease is present in a first-degree relative before 55 years of age for men and before 65 years of age for women.
This is known as the modified Framingham Risk Score.3
<4.1 0 0
Step 42,3
4.1-5.19 1 1 Using 10-year CVD risk from Step 2, determine if patient is Low, Moderate or High risk.† Indicate Lipid
5.2-6.19 2 3 and/or Apo B targets
6.2-7.2 3 4 Risk Level† Initiate Treatment If: Primary Target (LDL-C) Alternate Target
>7.2 4 5 • ≤2 mmol/L or ≥50% decrease • Apo B ≤0.8 g/L or
High • Consider treatment in all
Systolic Blood Not Not FRS ≥20% (Strong, High) in LDL-C • Non-HDL-C ≤2.6 mmol/L
Pressure (mmHg) Treated Treated (Strong, Moderate) (Strong, High)
Treated Treated
<120 -2 0 -3 -1 Intermediate • LDL-C ≥3.5 mmol/L • ≤2 mmol/L or ≥50% decrease • Apo B ≤0.8 g/L or
FRS 10-19% (Strong, Moderate) in LDL-C • Non-HDL-C ≤2.6 mmol/L
120-129 0 2 0 2 • For LDL-C <3.5 mmol/L (Strong, Moderate) (Strong, Moderate)
130-139 1 3 1 3 consider if:
• Apo B ≥1.2 g/L
140-149 2 4 2 5 • OR Non-HDL-C ≥4.3 mmol/L
150-159 2 4 4 6 (Strong, Moderate)
• Men ≥50 and women ≥60 with
160+ 3 5 5 7 1 risk factor: low HDL-C, impaired
fasting glucose, high waist
Yes 4 3 circumference, smoker,
Smoker
No 0 0 hypertension
Yes statin-indicated condition Low • statins generally not indicated • statins generally not indicated • statins generally
Diabetes
No 0 0 FRS <10% not indicated