Tuberculosis (3) Atf

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Last edited: 5/7/2023
TUBERCULOSIS
Tuberculosis Medical Editor: Aldrich Christiandy & Jude Logoya

I) REVIEW QUESTIONS WITH ANSWERS

QUESTIONS ANSWERS

1) Mycobacterium tuberculosis may proliferate within b) Inhibition of phagolysosome formation


macrophages due to
a) Inhibition of cytokine release
b) Inhibition of phagolysosome formation
c) Inhibition of phagocytic activity

2) 90% of the primary TB patients will progress into


primary progressive TB b) False
a) True
b) False 90% of the primary TB patients will go into the latent period of
TB

3) Combination of hilar lymphadenopathy + Ghon b) False


complex → Ghon focus
a) True Combination of hilar lymphadenopathy + Ghon focus → Ghon
b) False complex

4) Dysregulation of the hypothalamus may cause fever,


night sweats, and weight loss a) True
a) True
b) False

5) These complications below can be caused by a) True


tuberculosis
● Addison’s disease
● Bronchopneumonia
● Constrictive pericarditis
● Meningitis
● Scrofula
● Hepatitis
● Pneumothorax
● Pleural effusion
● Pott’s disease
● Osteomyelitis

a) True
b) False

1) What TST finding would you expect on someone a) 7 mm


immunocompromised presenting with fever, cough,
night sweats, chills, and weight loss?
a) 7 mm
b) 12 mm
c) 18 mm AfraTafreeh.com
d) 3 mm

2) An HIV patient had a 3 mm induration after TST c) Order IGRA


testing. What would you do next?
a) Treat the patient with the RIPE regimen
b) Order CXR or CT
c) Order IGRA
d) Treat with Rifampin for 4 months

3) The following findings suggest active TB in d) Fibrocalcification


radiographs EXCEPT:
a) Hilar lymphadenopathy
b) Caseating lesion
c) Consolidation
d) Fibrocalcification

Tuberculosis RESPIRATORY PATHOLOGY: Note #20. 1 of 2


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4) IDENTIFY. What is the gold standard in the diagnosis AFB smear + culture
of TB?

5) Patients who are asymptomatic with normal chest X- a) Isoniazid + Vit B6 for 9 months
ray but have (+) PPD should be treated with:
a) Isoniazid + Vit B6 for 9 months
b) RIPE regimen
c) Rifampin for 9 months
d) Isoniazid + Rifampin for 2 months

6) Patients with radiograph findings of TB should be a) Isoniazid with B6 + rifampin + ethambutol + pyrazinamide
treated with the following: for 2 months followed by rifampin + INH for 4 months
a) Isoniazid with B6 + rifampin + ethambutol +
pyrazinamide for 2 months followed by rifampin + INH
for 4 months
b) Isoniazid with B6 for 9 months
c) Isoniazid with B6 + rifampin + ethambutol +
pyrazinamide for 4 months
d) Rifampin for 9 months

For items 7-11, match the following adverse drug c) Pyrazinamide


reactions with their corresponding drugs:
e) Isoniazid
f) Rifampin
g) Pyrazinamide
h) Ethambutol
i) Streptomycin
7) Hepatotoxicity and hyperuricemia

8) Nephrotoxicity and ototoxicity e) Streptomycin

9) Optic neuritis d) Ethambutol

10) Red/orange urine and ↓active drug concentration b) Rifampin

11) Seizures, neuropathy, lactic acidosis, and a) Isoniazid


hepatotoxicity

2 of 2 RESPIRATORY PATHOLOGY: Note #20. Tuberculosis


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