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    Cholesterol Metabolism

    Uploaded by

    uthsala7123
    The document discusses cholesterol metabolism and regulation. It covers how cholesterol is synthesized in the body and transported via HDL. The roles of the liver and bile in cholesterol balance and excretion are examined. Dietary and drug treatments for high cholesterol are also mentioned.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd

    Cholesterol Metabolism

    Uploaded by

    uthsala7123
    20 views4 pages
    The document discusses cholesterol metabolism and regulation. It covers how cholesterol is synthesized in the body and transported via HDL. The roles of the liver and bile in cholesterol balance and excretion are examined. Dietary and drug treatments for high cholesterol are also mentioned.

    Original Description:

    A simple notes of cholesterol metabolism for MBBS students

    Original Title

    cholesterol metabolism

    Copyright

    © © All Rights Reserved

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    PDF, TXT or read online from Scribd

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    The document discusses cholesterol metabolism and regulation. It covers how cholesterol is synthesized in the body and transported via HDL. The roles of the liver and bile in cholesterol balance and excretion are examined. Dietary and drug treatments for high cholesterol are also mentioned.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    20 views4 pages

    Cholesterol Metabolism

    Uploaded by

    uthsala7123
    The document discusses cholesterol metabolism and regulation. It covers how cholesterol is synthesized in the body and transported via HDL. The roles of the liver and bile in cholesterol balance and excretion are examined. Dietary and drug treatments for high cholesterol are also mentioned.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    of 4

    Cholesleo 1elorolisn n to kg on, g

    mmbwan i t y b, ud oinanl
    tomonent de attls
    - Ve.Ds

    ,-Sleord hoawok
    tSbudwe

    desnohybonmmfn súnnsermnhese
    Catomg D,eC)
    t
    One -OHgp atgd þocrlon
    ouble bemd bw s&&'c

    A
    HC

    Phsawpkion
    Chasse hycholyzed by ch: usluase
    aL Ckinoporaud inb "rmallsabshed immuutesal t l
    Chs eeied, &incosporaud imo chyomicaons
    saachus blood shream Horoughlaerenls
    eloduy Ch suachaa liw rough chyloeniton venrnans
    U
    Role or litinCh bolance
    Xels Ch
    Ch oomexta hebalte l&sues
    Keveuse Ch tamspoxt via Hdl
    - Chxemramt

    T
    e movo &mheus
    lole shepakia ch
    VIl to 1L (Teonset b exa-tepako firue)
    pire extsekn ivndo brle
    Btle acid symthaui Aexcdion in bile
    Melemy&ali Je mouo sumiteais helesdeol emlieuea
    Jch ive extoa- e bali
    Live Reveve beavnspost
    Choo Cohbolfom
    3oliaoy excyekon
    bhdagenous lipopoolkin
    (2TovOsmlkesis oCh
    elylCoA+Aelylan Rele
    sumihae (oA AcledcehlOAcelyl
    GA CGA
    SIEL GAHMG CoA Sypoase STEP 2
    HMG CoA
    siay ste-ivoe (1g/d) NADtHMGA(oAsuducase sTGPaRaleJimibingd sy
    acbenal conex,ovanies Mevalenale (40)
    3ATP
    30pP Kinase0
    ecarboxylase
    STEP4
    auahion
    18Acekyl CoA+ lBAT? +16NADPH Isopootermlyoophosphate [5)
    +402 ISomedase
    mekiylally ophiocphale
    )
    Choleslerol +SCOtlo NePt | lamshe»qse STGPS
    +8A +18Pi
    Sage
    dg PP Spenevgl pyopkosphale
    ato7ms HMG (GA PR:Toamterase.
    b)feormos acsCmlemedias Fame Pyoasphale (isc)
    Usoaenoids) Saualene smhase.
    c)6ispremidsfomosajualee Saualene (30t)
    yualene 10 fom Ch Napeu.
    Epoxtdase &yehse STE
    lomosleol(3oc)

    Cholesleol (23)
    kequlshio, of Ch symikeetg
    Reulnliom
    on
    Jnhikoas
    Ch
    ne
    Srncileom

    Innglalfon
    Gilaragen HMGa lol edurhe
    sains

    Cempekltve ikler
    ipovalev medttakion Kie
    AMG COn
    ATe
    HMG Co
    edushae educhue P)
    (achfve Cnacke)
    Cholesleol okein phosbhalase Glucagon
    Isulio Imhibthoar i -0MP
    Ch also Jes Lbl suuphor amhuis-(uplake)LTACAT shovage)
    huin diüt1,sumtuis ted
    *Exdion of Cholesenol:
    vg.diek-300 mg/day exevetad Roough btle.
    e movo Syrnlus-F00 m/day. J000/daY-500mg
    Corvedad fo bile aude
    Choleslesol

    Ble a
    Bile aids
    Conjugakon
    Blesal Potl vin (Gnlauohepalic ulotion,93-/)

    -c8 *Cholesoroine. tveamept


    pauds suzy dimg
    Ciesalls mesi
    badia bileauds
    oglday) nhatin Jo.sg/dey(exdad mleces
    *Nusaional &havmauudual maama lor bualiq hauesuckolealestolerrnia
    Reeauimg imake odintay snluuatad fal to <3ot caosiea
    -uds ncluihfdo} LDLuuphox
    UMdate inake oh dithy choleslool lo aooma/dty
    it) Scomsmplion onúcous soluble, dúlasu tbre (1o-asg/a)
    -impaua abco»píom o dielasy ch
    SAabsonphno l&aieds
    -Bacial umaliom. of 3oluble tbyes, susulls, in aho»tdaim Ja.
    4Aakmay h silkass
    HMG-CoA Rduase imilitos.
    -Stalins.lovasltadainm)

    bpr0

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