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    Kaimax Brochure

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    kbeauty.pharma
    This document provides information about a botox product called Kaimax, including its composition, indications for use, dosage, and dilution instructions. It compares Kaimax to other botox products on attributes like purity, protein content, and origin of strain. Tables and diagrams show results of these comparisons and how Kaimax can be used for wrinkle reduction and skin/contour improvement.

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    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd

    Kaimax Brochure

    Uploaded by

    kbeauty.pharma
    70 views8 pages
    This document provides information about a botox product called Kaimax, including its composition, indications for use, dosage, and dilution instructions. It compares Kaimax to other botox products on attributes like purity, protein content, and origin of strain. Tables and diagrams show results of these comparisons and how Kaimax can be used for wrinkle reduction and skin/contour improvement.

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    Kaimax_brochure

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    This document provides information about a botox product called Kaimax, including its composition, indications for use, dosage, and dilution instructions. It compares Kaimax to other botox products on attributes like purity, protein content, and origin of strain. Tables and diagrams show results of these comparisons and how Kaimax can be used for wrinkle reduction and skin/contour improvement.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    70 views8 pages

    Kaimax Brochure

    Uploaded by

    kbeauty.pharma
    This document provides information about a botox product called Kaimax, including its composition, indications for use, dosage, and dilution instructions. It compares Kaimax to other botox products on attributes like purity, protein content, and origin of strain. Tables and diagrams show results of these comparisons and how Kaimax can be used for wrinkle reduction and skin/contour improvement.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    of 8

    1

    Botox Professional Company


    Botox-specialized exports for 10 years
    a trusted company
    High Purity with patented technology

    2 Global Products
    Global products exported to Asia, North America,
    South America and Europe

    3 Safe Products
    Safe production environment
    Accurate quality control
    Freeze-drying vs Vaccum-drying
    Freeze-drying is a water removal process by freezing the material, then reducing the pressure and adding heat to allow the frozen
    water in the material to sublimate.
    Vaccum-drying is a water removal process by reducing the ambient pressure, which lowers the heat needed for water to sublimate.

    The reason why the shape of the drug(white-cake) appears different between freeze-dried products and vacuum-dried products is
    the way of drying process.
    High Purity(99.8%), High Biological Activity
    55
    In freeze-drying process, excipients(albuminandNaCl) included in the botulinum toxin products create a structure during freezing 50

    process. When the frozen water sublimates, it creates holes in the structure, which increases the lights cattering and makes it appear 45
    40 30.386
    whiter. And beacuse water sublimates while maintaining the structure, the volume dosen't change, which makes the drug(white-
    35
    cake) to appear in a larger amount. 30
    On the other hand, in vacuum-drying process, water sublimes without freezing, and the excipients do not create a structure. 25
    Therefore, the volume and the size of the drug(white-cake) decreases during the water sublimation process, which reduces the 20
    15
    10

    Original Strain from European National Institute


    5
    0
    -5
    2 4 6 8 10 12 14 16 18 20 22 24 26 28 30 32 34 36 38 40 42 44 46 48 50 52 54 56 58 60

    Manufacturer Company A Company B Kaimax Classic Purity 99.8% Protein 22.48ng/100U

    Strain Hall A Hyper Unknown Genuine Hall A

    Commercialized strain
    Non-commercialized strain From terrain around
    Origin of Strain from European national
    from University lab Company B R&D center
    institute

    Wrinkle and Skin Improvement


    Low Protein Content, Low Immunogenicity Risk Kaimax can be used as a skin toxin for pore size reduction,
    excess sebum control,erythema and wrinkle improvement.
    Manufacturer Company A Company B Kaimax Classic

    Total protein 3.45ng/100U * 4.52ng/100U * 2.48ng/ 100U

    Purity N/A 98% 99.8%


    Slim and Defined Line Contouring
    ※ Clinical, Cosmetic and Investigational Dermatology 2018: 11 327-331, Comparison of botulinum neurotoxin type A formulations in Asia Kaimax can decrease the muscle volume volume for a lean
    and feminine shoulder line and narrower and defined jaw line.

    A B Kaimax Classic A B Kaimax Classic

    NA 3.45
    Purity 98% Protein 4.52

    99.8% 2.48
    Detailed Product Description
    [COMPOSITION] 1 vial contains [DESCRIPTION]
    Clostridium botulinum toxin type A (In-house) 100units(U) White or light-yellow dried powder in colorless and clear glass vial
    Human serum albumin (EP) 0.5 mg and should become colorless transparent or light-yellow liquid when
    Sodium chloride (USP) 0.9 mg diluted with normal saline.

    [COMPOSITION] 1 vial contains [INDICATIONS AND USAGE]


    Clostridium botulinum toxin type A (In-house) 200units(U) Kaimax (botulinum toxin type A for injection) is indicated: For the
    Human serum albumin (EP) 1.0 mg temporary improvement in the appearance of moderate to severe
    Sodium chloride (USP) 1.8 mg glabellar lines associated with corrugator muscle and/or procerus
    muscle acitivity in adult patients aged 19 to 65 years. High Purity Original Strains From EUROPE
    [DOSAGE AND ADMINISTRATION]
    1. Preparation and dilution methods
    Dilute to 100U/2.5ml (4U/0.1ml) with sterile, preservative-free 0.9% <Dilution table> 100units(U)
    sodium chloride injection.
    Diluent added to 100 Units/Vial Resulting dose(Units/0.1mL)
    2. Using a 30 gauge needle, a total of 20U is injected by injecting
    0.1mL into 5 areas of each of the two corrugator muscles and one 1.0mL 10.0units
    of the procerus muscles. (See picture below)
    2.0mL 5.0units
    4.0mL 2.5units
    [Dilution Method]
    Each vial of kaimax is to be reconstituted sterile, preservative- 8.0mL 1.25units
    free saline. 0.9% sodium chloride injection is the recommended
    diluent. Add an appropriate amount of diluent to a syringe. Slowly
    inject the diluent into the vials as this drug will become denatured if
    <Dilution table> 200units(U)
    a foam or a similar agitation occurs. Discard the vial if the vial was
    not filled with diluent in vacuum condition. Record the date and Diluent added to 200 Units/Vial Resulting dose(Units/0.1mL)
    time of dissolution on the lael and allow it to be administered within
    2.0mL 10.0units
    24 hours after dissolution. Once reconstituted, Kaimax should
    be stored in a refrigerator at 2~8℃. 4.0mL 5.0units
    When Kaimax is dissolved, it should be colorless and transparent
    5.0mL 4.0units
    and free from a foreign substance. Parenteral formulations should
    be examined for foreign substances and discoloration prior 8.0mL 2.5units
    to administration. It is not recommended to use one vial for 10.0mL 2.0units
    more than one patient since this drug and diluent contain no
    preservatives.
    Note: These dilutions are calculated for an injection volume of 0.1mL.
    ※ For detail information A decrease or increase in the dose is also possible by administering
    Please refer to the Online Medicine Library a smaller or larger injection volume (i.e., 0.05mL(50% decrease in
    (http://drug.mfds.go.kr) of Ministry of Food and Drug Safety dose) or 0.15mL(50% increase in dose)).
    #Botulinum Toxin #100unit #200unit
    #High Purity Original Strains From EUROPE

    BEFORE AFTER
    Forehead Forehead
    E-mail [email protected]

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