Signature Assignment 5 1

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During this assignment you will imagine that you are a cat breeder who desires to breed cats to

We will think about several genes in cats that help

STEPONE

A a

a Aa aa

a Aa aa

Suppose y
gene and the male is heterozygous in genotype
Step 1:
Step 2:
solid coat? 50 OFTHEKITTENSWOULDHAVEASOLIDCOAT

(Gene O) which is
located on the X chromosome. Orange coloration is therefore a X-linked trait. The
dominant (O) allele specifies orange fur since it blocks the production of eumelanin
(black); therefore, only pheomelanin (orange) is produced. The recessive allele (o)
allows both yellow and black pigment production. Female cats, possessing two X
chromosomes, can be orange (genotype O/O), black (genotype o/o), or a mottled mix
of orange and black called Tortoiseshell (genotype O/o). The Tortoiseshell phenotype
is due to a process called “random X-chromosome inactivation” that occurs in
mammalian females during embryonic development, whereby only one X
chromosome is functionally active while the other is condensed and inactive. Male
cats, with only one X chromosome cannot normally be tortoiseshell; rare XXY males
(extra X chromosome) can be Tortoiseshell. The dominant O allele of Orange will
block the effects of the A allele of gene A (1st scenario) and will thus block Tabby fur.

QUESTION 1

0 Y

X 0 X 0 0 XOY

XOXO XOY XoXo XoY XOXo X 0 Xoxo XoY


represents a cross between a male, orange cat and a female,
tortoiseshell cat Use the genotypes that include the X and Y chromosome as you set up the

Suppose you cross a male cat of genotype a/a, XO/Y to a female cat of genotype A/a, Xo/Xo

Determine the probability of each possible

QUESTION 2
Axon a a a

isEEEEEi
aXoAaxoxoAaxoYAaxoxo Aaxon
ii ii is name
en
e 25 AREEXPECTEDTOBEBLACK
f 50 OFFEMALEKITENSAREEXPECTEDTOBETORTOISESHELL

a.EEfiiEEEfs
Ijg

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