DETAILED School Bungsuan National Grade Level & Grade 10 (3rd

LESSON PLAN High School Quarter Quarter)

IN SCIENCE 10
Student Teacher James Kyle D.
Galvez
Date Learning Area Science 10
Time Allotted 60 minutes Topic Mutations

I.OBJECTIVES
A. Content The learners demonstrate an understanding of:
Standards 1. the information stored in DNA as being used to make proteins
2. how changes in a DNA molecule may cause changes in its product
3. mutations that occur in sex cells as being heritable
B. Performance The learners should be able to:
Standards The learners shall be able to acquire knowledge regarding homeostasis and
nervous system.
C. Learning The learners:
Competency Explain how mutations may cause changes in the structure and function of a
protein. (S10LT-IIIe-38)
D. Specific After discussing the lesson, the learners should be able to:
Objectives 1. Identify the different types of mutation,
2. Describe the possible results of a certain type of mutation; and
3. Appreciate the importance of having knowledge about mutation in our lives.
II. CONTENT Mutations
III. MELC’s
LEARNING
RESOURCES
A. References Science 10 Quarter 3 – Module 4 Protein Synthesis and Mutations
B. Other Internet, PowerPoint Presentation, Laptop,
Learning
Resources.

IV: TEACHER’S ACTIVITY STUDENT’S ACTIVITY

PROCEDURES
Greetings
Good afternoon, class! Good afternoon, Sir!

Opening Prayer
Everyone, let us pray. (The students will pray)
(Call a student), kindly lead the
prayer.

Before you take your seats please

arrange your chairs properly and pick
up pieces of paper.

Done? You can now take your seats. Yes Sir.

 Checking of Attendance
Who is absent today? None Sir.

A. Reviewing Are you all ready to learn? Yes, Sir!

previous lesson
or presenting new Good!
lesson
(ELICIT) Before we proceed to our lesson let us
first have a short review of our
previous topic.

Questions:

1. Describe the process of protein (answers may vary)

synthesis.
2. How does DNA contribute to
the process of making
proteins?
3. Why are proteins essential for
the functioning of our body?
B. Establishing a
purpose for the ANALYZE THE PICTURE!
lesson (Teacher shows pictures and students
will analyze them)
(answers may vary)
Guide Questions:
1. What mutations can you identify
in the pictures?
2. How do these mutations affect
genes or proteins?
3. Why are these mutations important
to understand in terms of health?
C. Presenting “In order for you to have a glimpse of
examples/ our lesson today, you will watch a
instances of the video about Mutation.”
new lesson
(ENGAGE) “Are you ready class?” “Yes, Sir”

(The video will be played via TV) (The students will watch the video and
listen attentively)
D. Discussing This time let us have a group activity.
concepts and I will group you into two. Please count
practicing new one to two starting from this side.
skills
(EXPLORE) Now, who are the group 1, please
stand… group 2?

Please gather with your groupmates

and choose your leader.

Group leaders please come forward.

I have here a manila paper with
materials for your activity. For the
sake of clarity, I will just give the
instructions ahead.

Together with your groupmates, you

will do the task I provided for each of
the group. Write your answers on the
manila paper and post them on the
board. After that I will check if your
answers are correct and clear the
misconceptions if there is so.

GROUP 1
ACTIVITY 3

GROUP 2
Activity 4:
Protein Synthesis and Mutations
Reflect on the following questions.
Write your answers on a separate
piece of paper.
1. Mutations can sometimes
happen in the sex
chromosomes. What do you
think are the effects if a female
has a missing sex
chromosome?
2. One beneficial mutation is
using point mutation in
improving food crops,
resulting in variation and
 yielding stronger, more
disease-resistant crops. What
outcomes can come about on
this type of mutation?
3. Films from the Marvel and DC
comics universes have shown
us endless mutation
possibilities if you could be a
character in any of these
universe, would you want to
have a mutation or not? If you
do want a mutation, what kind
would you want and why?

Rubrics for Group Activity

Criteria Correspondi
ng Point
Teamwork/ 5
Cooperation
Presentation 5
Relevance/ 5
Correctness of
Ideas

You have 10 minutes to finish the

task.

Time’s up! Please post you output on

the board.
F. Developing (Discussion proper)
mastery
(EXPLAIN)
E. Finding Guide Questions: Possible Answers:
practical 1. How might knowledge of different 1. Understanding mutation types helps
applications of mutation types help medical researchers create drugs that target
concepts and researchers develop targeted specific genetic abnormalities,
skills in daily therapies for genetic diseases? improving treatment effectiveness.
living 2. Can you provide an example of a 2. A missense mutation in the gene can
real-world situation where a lead to cystic fibrosis, impacting
missense mutation led to a lung function and overall health.
significant change in an 3. Knowing about mutations can
individual's health or physical influence family planning decisions,
characteristics?
 3. How could understanding such as opting for genetic
mutations impact the decisions of counseling or testing before having
parents planning to have children, children.
especially if there's a family
history of genetic disorders?
F. Making Guide Questions: Possible Answers:
generalizations 1. What are the types of mutations 1. Types of mutations include point
and abstractions and how do they affect genes? mutations, insertions, deletions, and
about the lesson 2. How does a missense mutation chromosomal abnormalities. They
(ELABORATE) differ from a nonsense mutation can alter gene function by changing
and what can result from each? the DNA sequence.
3. How does knowing about 2. A missense mutation changes one
mutations help improve medical amino acid in a protein, potentially
treatments and personalized care? affecting its function. A nonsense
4. Why is genetic testing important mutation creates a premature stop
for finding mutations and
codon, leading to a nonfunctional
preventing diseases?
protein.
5. Why is it important for people to
3. Understanding mutations leads to
understand mutations for making
healthcare decisions and genetic better treatments tailored to
counseling? individual genetic profiles.
4. Genetic testing helps identify
mutations early, allowing for
preventive measures against genetic
diseases.
5. Understanding mutations is crucial
for making informed healthcare
choices based on genetic risks.
G. Evaluation (Assessment of Learning)
MULTIPLE CHOICE.
Answer the following questions. Choose the letter of the correct answer and write your answer on ¼
sheet of paper.
1. What type of mutation is characterized as heritable from parents?
A. Germline mutation
B. Point mutation
C. Frameshift mutation
D. Somatic mutation
2. This type of mutation is caused by nucleotide insertion or deletion.
A. Germline mutation
B. Point mutation
C. Frameshift mutation
D. Somatic mutation
3. Which of the following disorder is caused by a Duplication?
A. Hemophilia A
B. Pallister Killian syndrome
C. Cri-du-chat syndrome
D. Chronic Myeloid Leukemia or CML
4. Which type of chromosomal mutation causes Cri-du-chat syndrome?
A. Duplication
B. Insertion
C. Translocation
 D. Deletion
5. What is the importance of having knowledge about mutations in our lives?
A. They help us understand genetic diseases and develop treatments.
B. They contribute to advances in medical research and personalized healthcare for humans.
C. They enable us to track evolutionary changes in species.
D. All of the above.
H. EXTEND (Assignment)
Students will be assigned to complete Performance Task 3.

Prepared by: Checked by:

JAMES KYLE D. GALVEZ CATHERINE B. DALISAY

Student Teacher Cooperating Teacher