MASKS+ +Review+of+Literature
MASKS+ +Review+of+Literature
MASKS+ +Review+of+Literature
2
THE HIERARCHY OF EVIDENCE
Gold standard
studies
Non experimental
observational
studies
3
BUT THE "EXPERTS"
Gary Klass
Department of Politics and Government
Illinois State University
Kamran Abbasi, MD
British Medical Journal
Department of Primary Care and Public Health Executive
Editor of the British Medical Journal
5
THE META-ANALYSES &
SYSTEMATIC REVIEWS
Highest level of research
6
YEAR: 2009
SYSTEMATIC REVIEW EVIDENCE QUALITY: HIGH
SETTING: COMMUNITY & HEALTHCARE
Conclusion
While there is some experimental evidence that masks
should be able to reduce infectiousness under
controlled conditions, there is even less evidence on
whether this translates to effectiveness in natural
settings. There is little evidence to support the
effectiveness of face masks to reduce the risk of
infection.
Cross-sectional /
observational studies don't
have the power to adequately
measure interventional
outcomes, but they also found
no overall protective effects of
face masks.
8
Epidemiol Infect. 2010 Apr;138(4):449-56. doi: 10.1017/S0950268809991658.
YEAR: 2020
META-ANALYSIS EVIDENCE QUALITY: HIGHEST
SETTING: COMMUNITY
10
Canadian Family Physician July 2020, 66 (7) 509-517;
YEAR: 2012
SYSTEMATIC REVIEW EVIDENCE QUALITY: HIGH
SETTING: COMMUNITY & HEALTHCARE
Discussion:
None of the studies we reviewed established a
conclusive relationship between mask ⁄ respirator use
and protection against inuenza infection.
Results:
We included three trials, involving a total of 2106
participants. There was no statistically significant
difference in infection rates between the masked and
unmasked group in any of the trials.
Conclusion:
Examination of the literature revealed much of the
published work on the matter to be quite dated and
often studies had poorly elucidated methodologies.
Results:
No significance difference in the incidence of
postoperative wound infection was observed between
masks group and groups operated with no masks (1.34,
95% CI, 0.58-3.07). There was no increase in infection
rate in 1980 when masks were discarded. In fact there
was significant decrease in infection rate (p < 0.05).
Results:
In the meta-analysis of the clinical studies, we found no
significant difference between N95 respirators and
surgical masks in associated risk of (a) laboratory-
confirmed respiratory infection.
This
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ask.
Results:
A total of six RCTs involving 9171 participants were
included. There were not statistically significant
differences in preventing laboratory-confirmed
influenza, laboratory-confirmed respiratory viral
infections, laboratory-confirmed respiratory infection
and influenza-like illness using N95 respirators and
surgical masks.
Results
Our results show that masks alone have no significant
effect in interrupting spread of ILI or influenza in the all
populations analysis. Our findings are similar for ILI in
healthcare workers RR 0.37 (95% CIs 0.05 to 2.50) and
for the comparisons between N95 respirators and
surgical masks: for clinical respiratory illness, and
influenza.
18
YEAR: 2015
Randomized Controlled Trial EVIDENCE QUALITY: HIGH
SETTING: HEALTHCARE
Results
Cloth masks resulted in significantly higher rates of
infection than medical masks, and also performed
worse than the control arm.
Results
Our results suggest that the recommendation to wear a
surgical mask when outside the home among others did
not reduce, at conventional levels of statistical
significance, the incidence of SARS-CoV-2 infection in
mask wearers in a setting where social distancing and
other public health measures were in effect, mask
recommendations were not among those measures, and
community use of masks was uncommon.
Results
Rates of clinical respiratory illness (relative risk (RR)
0.61, 95% CI 0.18 to 2.13), ILI (RR 0.32, 95% CI 0.03 to
3.13) and laboratory-confirmed viral infections (RR 0.97,
95% CI 0.06 to 15.54) were not statistically significant
between the the mask arm compared with control.
23
THIS IS A TYPICAL CITY'S WEBSITE
EXPLAINING 'WHY MASKS WORK'
jeffco.us/4056/Mask-Guidance 24
THEY CLAIM THE FACT
Masks appear to help keep Filtration studies cannot
the person wearing the mask access if masking the
from spreading COVID-19 to general public will in-fact
others by reducing the reduce viral transmission,
amount and distance only a Randomized Control
infectious particles can Trial that measures efficacy
spread through partial of interventions can
filtering of said particles. appropriately do this.
jeffco.us/4056/Mask-Guidance 25
THEY CLAIM THE FACT
In yet another instance, two This is a REPORT on the
infected hair salon CDC's owned Morbidity and
employees in Missouri did not Mortality Weekly Report
transmit any apparent website. It is a not a peer
infections to any of their 139 reviewed scientific study.
clients in the setting of mask
use by them and nearly all of
their clients.
jeffco.us/4056/Mask-Guidance 26
Why do they omit ALL the randomized
controlled trials & the
meta-analyses we have on this?
27
JOURNAL OF THE AMERICAN
EDITORIAL
MEDICAL ASSOCIATION
https://www.who.int/publications/i/item/advice-on-the-use-of-masks-in-the-
community-during-home-care-and-in-healthcare-settings-in-the-context-of-the-
novel-coronavirus-(2019-ncov)-outbreak 30
JAMA HEALTH
WORLD ARTICLE
ORGANIZATION
https://www.who.int/publications/i/item/advice-on-the-use-of-masks-in-the-community-during-home-
care-and-in-healthcare-settings-in-the-context-of-the-novel-coronavirus-(2019-ncov)-outbreak
31
THOUSANDS OF
PROFESSIONALS SPEAK OUT
32
"As for the scientific support for the use of face masks, a recent
careful examination of the literature, in which 17 of the best studies
were analyzed, concluded that, “None of the studies established a
conclusive relationship between mask/respirator use and
protection against influenza infection.
Russell Blaylock, MD
Jim Meehan, MD
“Face masks in public places are not necessary, based on all the
current evidence. There is no benefit and there may even be
negative impact.”
Coen Berends
National Institute for Public Health and the Environment
33
"We know that wearing a mask outside healthcare facilities offers
little, if any, protection from infection. Public health authorities
define a significant exposure to CoVID-19 as face-to-face contact
within 6 feet with a patient with symptomatic CoVID-19 that is
sustained for at least a few minutes (and some say more than 10
minutes or even 30 minutes). The chance of catching CoVID-19
from a passing interaction in a public space is therefore minimal. In
many cases, the desire for widespread masking is a reflexive
reaction to anxiety over the pandemic."
Michael Klompas, MD
Charles A. Morris, MD
Julia Sinclair, MBA
Madelyn Pearson, DNP
Erica S. Shenoy, MD
"Face masks should not be seen as a magic bullet that halts the
spread."
Christian Hoebe
Professor of infectious diseases
34
"Sweeping mask recommendations—as many have proposed—
will not reduce SARS-CoV-2 transmission, as evidenced by the
widespread practice of wearing such masks in Hubei province,
China, before and during its mass COVID-19 transmission
experience earlier this year...
35
"The fact that this virus is a relatively benign infection for the
vast majority of the population and that most of the at-risk
group also survive, from an infectious disease and
epidemiological standpoint, by letting the virus spread through
the healthier population we will reach a herd immunity level
rather quickly that will end this pandemic quickly and prevent a
return next winter. During this time, we need to protect the at-
risk population by avoiding close contact, boosting their
immunity with compounds that boost cellular immunity and in
general, care for them.One should not attack and insult those
who have chosen not to wear a mask, as these studies suggest
that is the wise choice to make."
Russell Blaylock, MD
Neuroseurgon
Gabriel Cousens, MD
Elke De Klerk, MD
Founder of Doctors for Truth
37
THE GREAT BARRINGTON
DECLARATION
MISSION
"As infectious disease epidemiologists and public health
scientists we have grave concerns about the damaging
physical and mental health impacts of the prevailing
COVID-19 policies, and recommend an approach we call
Focused Protection."
gbdeclaration.org 38
WORLD DOCTORS
ALLIANCE
MISSION
An independent non-profit alliance of doctors, nurses,
healthcare professionals and staff around the world who
have united in the wake of the Covid-19 response chapter
to share experiences with a view to ending all lockdowns
and related damaging measures and to re-establish
universal health determinance of psychological and
physical wellbeing for all humanity.
MISSION
The Victorian government’s response to the SARS-CoV-2
virus is now doing more harm than good. These measures
will cause more deaths and result in far more negative
health effects than the virus itself. Left unchecked, the
Victorian government risks creating the state’s worst ever
public health crisis.
covidmedicalnetwork.com
40
Non Exhaustive List of Professionals That Do
Not Support Mandates for the General Public
Dr. Alexander Walker, former Chair of Epidemiology, Harvard
Dr. Andrius Kavaliunas, epidemiologist
Dr. Angus Dalgleish, oncologist, infectious disease expert
Dr. Annie Janvier, professor of pediatrics and clinical ethics
Dr. Ariel Munitz, professor clinical microbiology and immunology
Dr. Boris Kotchoubey, Institute for Medical Psychology
Dr. Cody Meissner, professor of pediatrics, vaccine development
Dr. David Katz, founder Yale Prevention Research Center
Dr. David Livermore, microbiologist, infectious disease
Dr. Eitan Friedman, professor of medicine
Dr. Eyal Shahar, physician, epidemiologist
Dr. Florian Limbourg, physician and researcher
Dr. Gabriela Gomes, mathematician studying epidemiology
Dr. Gerhard Krönke, physician and professor
Dr. Gesine Weckmann, professor of health education and prevention
Dr. Günter Kampf, Institute for Hygiene and Environmental Medicine
Dr. Helen Colhoun, professor of medical informatics epidemiology
Dr. Jonas Ludvigsson, pediatrician, epidemiologist and professor
Dr. Karol Sikora, physician, oncologist, and professor of medicine
Dr. Laura Lazzeroni, professor of psychiatry and behavioral sciences
Dr. Lisa White, professor of modeling and epidemiology, Oxford
Dr. Mario Recker, malaria researcher and associate professor
Dr. Matthew Strauss, critical care physician & professor of medicine
Dr. Michael Jackson, research fellow
Dr. Michael Levitt, biophysicist, recipient 2013 Nobel Prize Chemistry
Dr. Mike Hulme, professor of human geography
Dr. Motti Gerlic, professor of clinical microbiology and immunology
Dr. Partha P. Majumder, National Institute of Biomedical Genomics
Dr. Paul McKeigue, professor of epidemiology and public health
Dr. Rajiv Bhatia, physician, epidemiologist and public policy expert
41
Non Exhaustive List of Professionals That Do
Not Support Mandates for the General Public
Dr. Rodney Sturdivant, infectious disease scientist
Dr. Salmaan Keshavjee, professor Harvard Medical School
Dr. Simon Thornley, epidemiologist and biostatistician
Dr. Simon Wood, biostatistician and professor
Dr. Stephen Bremner, professor of medical statistics
Dr. Sylvia Fogel, instructor Harvard Medical School
Dr. Udi Qimron, professor of clinical microbiology and immunology
Dr. Ulrike Kämmerer, professor and expert in virology, immunology
Dr. Uri Gavish, biomedical consultant
Andrew Kaufman, MD Josh Henk, DC
Scott Jensen, MD Jay Komarek, DC
Eddie Weller, DC Josh Howe, DC
Allison Lucas, Esq Jocobey Mark, DC
Gabriel Cousens, MD Joseph Mercola, DO
Eric Nepune, DC Cassie Huckaby, ND
Jessica Peatross, MD Ben Lynch, ND
Josheph Arena, DC Morgan Towles, DC
Liam Schubel, DC Alex Lee, DC
Daniel Knowles, DC Rashid Buttar, DO
Kelly Brogan, MD Edith Chan, DAOM
Suzan Tenpenny, MD Tyna Moore, DC, ND
Tom Cowen, MD Suneil Jane, NMD
Tommy John, DC Ashton Joyce, NMD
Joseph Audie, PhD Jo Yi, MD
Denis Rancourt, PhD Melanie Joy, PhD
Zev Myerowitz, DC Melissa Sell, DC
Seth Gerlach, DC Christiane Northrup, MD
Ben Tapper, DC Zack Bush, MD
Lauren Keller, APRN Michael Christian, DHSc, CMS
Sarah Carnes, ND Shiva Ayyadurai, PhD
THOUSANDS MORE 42