KARACHI MEDICAL AN DENTAL COLLEGE

PRE-PROFF EXAMINATION 2019

FOUNDATION MODULE

1.The fixed permanent cells of connective tissue includes all except:

a) Mesenchymal cells.
b) Fibroblast
c) Mast cells
d) Adipocytes
2.The stratified squamous non-keratinized epithelium is present in:
a) Oral cavity
b) Peritoneum
c) Stomach
d) Whole GIT
3.Which of the following is also called low resistance junction
a) Junctional epithelium
b) Junctional complex
c) Tight junction
d) Gap junction
4.All of the following are membranous except:
a) Peroxisome
b) Endoplasmic reticulum
c) Centriole
d) Mitochondria
5.Which of the following is suitable for peripheral blood smears
a) Hematoxylin and eosin
b) Romanowsky stain
c) Methylene blue
 d) None of the above
6.Transition epithelium shows:
a) Goblet cells
b) Bi-nucleated cells
c) Lipid droplets
d) Melanin
7.The dense irregular connective tissue is present in:
a) Dermis
b) Gland Capsule
c) Epidermis
8.sebacous gland is an example of:
a) Simple acinar
b) Simple branched acinar
c) Compound acinar
d) Compound tubule acinar
9.compound tubulo-alveolar glands are present in:
a) Pancreas
b) Stomach
c) Epidermis
d) Skin
10.epithelium of thin skin lacks:
a) Stratum basalis
b) Stratum corneum
c) Stratum spinosum
d) Stratum lucidum
11.The pre- ganglionic cell of sympathetic nervous system are present in:
a) Interior horn of cervical
b) Spinal ligaments
12.cranial parasympathetic ganglion includes all except:
a) Celotic ganglion
b) Ciliary ganglion
c) Spino palatine ganglion
d) Pterygopalatine ganglion
13.Example of end artery is:
a) Axillary artery
b) Coronary artery
c) Epiphyseal artery
d) Metaphyseal artery
14.The growth plate of long bone is:
a) Diaphysis
b) Epiphysis
c) metaphysis
d) endosteum
15.amniotic cavity is lined by:
a) Epiblast and amnioblast
b) hypoblast
c) endoderm
d) ectoderm
16.Gastrulation leads to:
a) Primitive streak
b) Neural tube
c) Morula
d) Blastula
17. Event occurring in the 3rd week of development is :
a) Primitive streak appearance
b) Laying down of extraembryonic mesoderm
c) Formation of primary villi
18.Events occurring in the 2nd week of development is:
 a) Appearance of primitive streak
b) Laying down of extraembryonic mesoderm
c) Formation of allanto enteric canal
d) Formation of tertiary villi
19.Components of definitive chorion:
a) Extraembryonic somatic mesoderm, cytotrophoblast, syncytiotrophoblast
b) Extraembryonic mesoderm and epiblast.
c) Extraembryonic visceral mesoderm
d) Intraembryonic mesoderm.
20.After parturition the gynecologist identify the maternal surface of placenta
due to 15 to 20 bulging areas called:
a) Cotyledons
b) Placental septa
c) Intravenous base
d) Cytotrophoblast cells
21.the morula:
a) contains cells called blastomeres
b) have pre distinctive cell types
c) at birth is 500 gm similar to gastrula and blastula
22.Klinefilter’s syndrome is the defect of:
a) Autosomes
b) Lysosomes
c) Sex chromosomes
d) Monosomes
23.the alpha feto-protein level is increased, the most probable fetal diagnosis is:
a) Anencephaly
b) Sacrococcygeal teratoma
c) Hydatidiform mole
d) Renal agenesis
24.which of the following is a normal content of umbilical cord:
 a) Wharton’s jelly
b) Interstitial loop
c) Two veins
25.Phospholipids in cell membrane is important because:
a) They have glycerol
b) They can form bi-layers in water
c) They have both polar and non-polar proteins
d) They combine covalently with proteins
26.In double stranded DNA molecule:
a) Total number of purine bases are equal to total number of pyrimidine bases
b) Only one of the bases is replicated
c) The two strands are parallel
d) Purine bases are more then the pyrimidine
27.Diets that have the highest ratio of polyunsaturated fatty acids can cause:
a) Increased triglycerides
b) Increased cholesterol
c) Decreased HDL
d) Increased LDL
28.Production of which of the following protein would be directly affected in
scurvy:
a) Myoglobin
b) Collagen
c) Hemoglobin
d) Insulin
29.In the DNA replication the enzyme required in the first step is:
a) DNA directed polymerase
b) Unwinding proteins
c) DNA polymerase
30.Genetic code operates via:
a) Protein moieties of DNA
 b) Base sequence of DNA
c) Base sequence of tRNA
d) Nucleotide sequence of mRNA
31.N-acetylgalactosamine is present in:
a) Chondroitin sulphate
b) Heparin
c) Hyaluronic acid
d) Keratin sulphate
32.Isomers differing as a result of difference of OH and H configuration on carbon
number 2,3 and 4 are known as:
a) Epimer
b) Anomer
c) Stereo isomers
d) Optical isomers
33.Amino acid required for the synthesis of many hormone is:
a) Alanine
b) Histidine
c) Phenylalanine
d) Valine
34.RNA do not have:
a) Uracil
b) Adenine
c) Guanine
d) Thymine
35.Self amplifying chain of physiological function:
a) Positive feedback
b) Negative feedback
c) Homeostasis
d) CNS
36.A 62 year old female eats a high carbohydrate content meal her plasma
glucose level rises and this results in increase release of insulin from pancreatic
cells. The insulin release is an example of:
a) Positive feedback
b) Negative feedback
c) Equilibrium
d) NOTA
37.Proteins that are secreted by the cells are generally:
a) Synthesize on agranular endoplasmic reticulum
b) Move across the cell membrane through endocytosis
c) Found in vesicles
d) Alters the composition of cytosol
38.Function of membrane bounded endoplasmic reticulum having agranular
structure is:
a) Glycosylation
b) Steroid synthesis
c) Protein synthesis
d) Energy production
39.Which one of the following structure maintains fluidity in cell membrane:
a) Phospholipid
b) Glycoprotein
c) Glycolipid
d) Cholesterol
40.A medical student examine a cell under microscope, he found certain
structure. Ribosomes are found in:
a) Mitochondria
b) Lysosomes
c) Rough ER
d) Smooth ER
41.Cellular organelles containing hydrolytic enzymes are:
 a) Peroxisomes
b) Lysosomes
c) Ribosomes
d) Mitochondria
42.Which of the following is not the function of mitochondria:
a) Electron transport chain and ATP
b) Glycolysis and ATP production
c) Non shivering thermogenesis
43.Mitochondria is not present in the following cells except:
a) Hepatocytes
b) Cardiac muscles cells
c) Skeletal muscle cells
d) Mature RBCs
44.packaging is the role of:
a) Golgi bodies
b) Mitochondria
c) Endoplasmic reticulum
d) Nucleolus
45.Which structure maintains fluidity of cell membrane:
a) Phospholipid
b) Glycolipid
c) Glycoproteins
d) Cholesterol
46.Which set is related to homeostasis mechanism:
a) Thermoregulation, set point, effector
b) Sensor, integrator, effector
c) Effector, response, set point
d) Sensor, responder, effector
47.The synthesis of protein is the function of:
a) Lysosomes
 b) Nucleus
c) Cell membrane
d) Mitochondria
48.The body uses energy in the form of?
a) Proteins
b) Carbohydrates
c) Fats
d) ATP
49. Which one has a role in detoxifying drugs, alcohol and carcinogens:
a) Rough ER
b) Smooth ER
c) Lysosomes
d) peroxisomes
50.which molecule synthesize CHO such as hyaluronic acid and chondroitin
sulphate:
a) Rough ER
b) Smooth ER
c) Golgi apparatus
d) Mitochondria
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COMPILED BY NAHAL-E-AMNA