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    The Human Genome Project (HGP)

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    Emily Trapstar
    The Human Genome Project (HGP) was an international research project that aimed to determine the complete DNA sequence of the human genome and map all of the genes. The goal was to generate the first sequence of the human genome. It was carried out from 1990-2003. The HGP helped scientists better understand human evolution, common biology shared with other organisms, and the role of genes in wellness and disease. Comparative genomics with other species led to identifying similar genes associated with diseases and traits. The HGP also aided in developing diagnostics and therapeutics to ultimately prevent and treat complex genetic disorders.

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    The Human Genome Project (HGP)

    Uploaded by

    Emily Trapstar
    84 views2 pages
    The Human Genome Project (HGP) was an international research project that aimed to determine the complete DNA sequence of the human genome and map all of the genes. The goal was to generate the first sequence of the human genome. It was carried out from 1990-2003. The HGP helped scientists better understand human evolution, common biology shared with other organisms, and the role of genes in wellness and disease. Comparative genomics with other species led to identifying similar genes associated with diseases and traits. The HGP also aided in developing diagnostics and therapeutics to ultimately prevent and treat complex genetic disorders.

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    The Human Genome Project (HGP) was an international research project that aimed to determine the complete DNA sequence of the human genome and map all of the genes. The goal was to generate the first sequence of the human genome. It was carried out from 1990-2003. The HGP helped scientists better understand human evolution, common biology shared with other organisms, and the role of genes in wellness and disease. Comparative genomics with other species led to identifying similar genes associated with diseases and traits. The HGP also aided in developing diagnostics and therapeutics to ultimately prevent and treat complex genetic disorders.

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    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    84 views2 pages

    The Human Genome Project (HGP)

    Uploaded by

    Emily Trapstar
    The Human Genome Project (HGP) was an international research project that aimed to determine the complete DNA sequence of the human genome and map all of the genes. The goal was to generate the first sequence of the human genome. It was carried out from 1990-2003. The HGP helped scientists better understand human evolution, common biology shared with other organisms, and the role of genes in wellness and disease. Comparative genomics with other species led to identifying similar genes associated with diseases and traits. The HGP also aided in developing diagnostics and therapeutics to ultimately prevent and treat complex genetic disorders.

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    The HGP can help us understand

    Genome – the complete set of genes in a cell


    human evolution and the common
    Proteome – the full range of proteins that a biology we share with all of life.
    The Human Genome Project (HGP)
    cell is able to produce Comparative genomics between
    is an international research project
    humans and other organisms such as
    aimed to study all the genetic
    mice has led to similar genes
    content of the chromosomes of
    associated with diseases and traits.
    the human organisms (the human
    genome).
    The HGP has allowed scientists to
    better understand wellness and
    The goal of the HGP was disease by using information on the
    to generate the first The Human sequence and location of human
    genes.
    sequence of the human
    genome. Genome Project
    The HGP has also helped for the
    (HGP) development of diagnostics and
    advanced therapeutics, which may
    It was carried out from 1990-2003. ultimately provide the means for
    the prevention and targeted
    treatment of complex genetic
    disorders such as cancer.

    The researchers from the project recruited


    volunteers as their sample and collected blood
    DNA sequencing involves determining the exact samples from them. Most of the human genome
    order of the bases in DNA. The project used the sequence generated by the HGP came from blood
    advanced sanger DNA sequencing method. This donors.
    involves using a purified DNA polymerase enzyme to
    synthesise DNA chains of varying length.
    Timeline of events
    1993 – the Sanger 1996 – representatives 1999 – DNA sequencing of
    2003 – the “Gold
    centre was opened with from sequencing centres human genome begins.
    1985 – the first standard” references
    1990 – human funding. The British arm across the world meet in
    meeting held by The Sanger centre finishes of human genome
    genome project was of HGP launched at Bermuda to draft a set of
    Robert Sinsheimer the sequence of first the sequence is officially
    launched in USA and Sanger centre. principles for the HGP data.
    to propose the human chromosome, completed to 99.99%
    directed by James These are known as
    sequencing of the Francis Collins is now chromosome 22, the accuracy.
    Watson. Bermuda principles.
    human genome the director of HGP. second smallest autosome.

    1988 – the human 1992 – John Sulston 1998 – Celera genomics 2001 – the HGP
    1994 – scientists
    genome organisation submits a grant application launches a private and Celera
    finish the major
    (HUGO), an proposing they fund his venture to finish genomics both
    mapping stage of
    international nematode worm sequencing of human publish their draft
    HGP.
    organisation of sequencing project and genome in three years sequences.
    scientists involved in begin the UK’s contribution The HGP reaches its
    human genetics, was to the HGP. midpoint.
    founded.
    James Watson leaves his
    position as director of HGP.

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