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    Icsc 0091 - Acrylamide

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    Putri Nadya Kamila
    Acrylamide is a white crystalline solid that is combustible and gives off irritating or toxic fumes when burned. It can form explosive mixtures in air and dust particles. Acrylamide is toxic if swallowed, harmful if inhaled or in contact with skin, and causes skin, eye and respiratory irritation. Long term exposure may cause cancer, genetic defects, and damage to the nervous system and reproductive toxicity. Occupational exposure limits and protective equipment are recommended to prevent worker exposure.

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    Icsc 0091 - Acrylamide

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    Putri Nadya Kamila
    10 views2 pages
    Acrylamide is a white crystalline solid that is combustible and gives off irritating or toxic fumes when burned. It can form explosive mixtures in air and dust particles. Acrylamide is toxic if swallowed, harmful if inhaled or in contact with skin, and causes skin, eye and respiratory irritation. Long term exposure may cause cancer, genetic defects, and damage to the nervous system and reproductive toxicity. Occupational exposure limits and protective equipment are recommended to prevent worker exposure.

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    ICSC 0091 - ACRYLAMIDE

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    Acrylamide is a white crystalline solid that is combustible and gives off irritating or toxic fumes when burned. It can form explosive mixtures in air and dust particles. Acrylamide is toxic if swallowed, harmful if inhaled or in contact with skin, and causes skin, eye and respiratory irritation. Long term exposure may cause cancer, genetic defects, and damage to the nervous system and reproductive toxicity. Occupational exposure limits and protective equipment are recommended to prevent worker exposure.

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    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    10 views2 pages

    Icsc 0091 - Acrylamide

    Uploaded by

    Putri Nadya Kamila
    Acrylamide is a white crystalline solid that is combustible and gives off irritating or toxic fumes when burned. It can form explosive mixtures in air and dust particles. Acrylamide is toxic if swallowed, harmful if inhaled or in contact with skin, and causes skin, eye and respiratory irritation. Long term exposure may cause cancer, genetic defects, and damage to the nervous system and reproductive toxicity. Occupational exposure limits and protective equipment are recommended to prevent worker exposure.

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    of 2

    11/6/23, 9:56 PM ICSC 0091 - ACRYLAMIDE

    ACRYLAMIDE ICSC: 0091 (October 2013)


    2-Propene amide
    Acrylic acid amide
    Vinyl amide
    CAS #: 79-06-1
    UN #: 2074
    EC Number: 201-173-7

    ACUTE HAZARDS PREVENTION FIRE FIGHTING


    Combustible. Gives off irritating or
    FIRE & toxic fumes (or gases) in a fire. NO open flames. Prevent deposition Use water spray, powder, alcohol-
    EXPLOSION Finely dispersed particles form of dust. resistant foam, carbon dioxide.
    explosive mixtures in air.

    PREVENT DISPERSION OF DUST! AVOID ALL CONTACT! IN ALL CASES CONSULT A DOCTOR!
    SYMPTOMS PREVENTION FIRST AID
    Use closed system or breathing Fresh air, rest. Refer for medical
    Inhalation Cough. Sore throat. Weakness.
    protection. attention.
    Remove contaminated clothes.
    Rinse skin with plenty of water or
    MAY BE ABSORBED! Redness. Protective gloves. Protective
    Skin Pain. clothing.
    shower. Refer for medical attention .
    Wear protective gloves when
    administering first aid.
    First rinse with plenty of water for
    Wear face shield or eye protection in
    several minutes (remove contact
    Eyes Redness. Pain. combination with breathing
    lenses if easily possible), then refer
    protection.
    for medical attention.
    Rinse mouth. Give one or two
    Abdominal pain. Weakness. See Do not eat, drink, or smoke during
    Ingestion Notes. work.
    glasses of water to drink. Refer
    immediately for medical attention.

    SPILLAGE DISPOSAL CLASSIFICATION & LABELLING


    Consult an expert! Personal protection: chemical protection suit
    including self-contained breathing apparatus. Do NOT let this According to UN GHS Criteria
    chemical enter the environment. Sweep spilled substance into
    covered sealable containers. If appropriate, moisten first to
    prevent dusting. Carefully collect remainder. Then store and
    dispose of according to local regulations.

    DANGER
    Toxic if swallowed
    STORAGE Harmful in contact with skin or if inhaled
    Causes skin irritation
    Separated from incompatible materials. See Chemical Dangers. Causes serious eye irritation
    Cool. Keep in the dark. Well closed. Store in an area without May cause an allergic skin reaction
    drain or sewer access. May cause genetic defects
    May cause cancer
    Suspected of damaging fertility or the unborn child
    Causes damage to nervous system
    PACKAGING Causes damage to the nervous system through prolonged or
    repeated exposure
    Special material.
    Do not transport with food and feedstuffs. Transportation
    Special packaging required. UN Classification
    UN Hazard Class: 6.1; UN Pack Group: III

    Prepared by an international group of experts on behalf of ILO and WHO,


    with the financial assistance of the European Commission.
    © ILO and WHO 2021

    https://www.ilo.org/dyn/icsc/showcard.display?p_lang=en&p_card_id=0091&p_version=2 1/2
    11/6/23, 9:56 PM ICSC 0091 - ACRYLAMIDE

    ACRYLAMIDE ICSC: 0091


    PHYSICAL & CHEMICAL INFORMATION

    Physical State; Appearance Formula: C3H5NO / CH2=CH-CONH2


    WHITE CRYSTALS. Molecular mass: 71.1
    Melting point: 84.5°C
    Physical dangers
    Density: 1.13 g/cm³
    Solubility in water, g/100ml at 25°C: 204 (very good)
    Chemical dangers Vapour pressure, Pa at 25°C: 0.9
    Relative vapour density (air = 1): 2.45
    The substance polymerizes violently due to heating above 85°C or
    under the influence of light and oxidants. It reacts with strong bases Flash point: 138°C c.c.
    Auto-ignition temperature: 424°C
    and strong oxidants. Decomposes on burning. This produces toxic and
    corrosive fumes including nitrogen oxides. Octanol/water partition coefficient as log Pow: -0.78

    EXPOSURE & HEALTH EFFECTS

    Routes of exposure Inhalation risk


    The substance can be absorbed into the body by inhalation, through Evaporation at 20°C is negligible; a harmful concentration of airborne
    the skin and by ingestion. particles can, however, be reached quickly.

    Effects of short-term exposure Effects of long-term or repeated exposure


    The substance is irritating to the eyes, skin and respiratory tract. The Repeated or prolonged contact may cause skin sensitization. The
    substance may cause effects on the nervous system. The effects may substance may have effects on the nervous system. This may result in
    be delayed. peripheral nerve damage. This substance is probably carcinogenic to
    humans. May cause heritable genetic damage to human germ cells.
    May cause toxicity to human reproduction or development. Repeated
    or prolonged contact with skin may cause dermatitis. See Notes.

    OCCUPATIONAL EXPOSURE LIMITS


    TLV: (inhalable fraction and vapour): 0.03 mg/m3, as TWA; (skin); (DSEN); A2 (suspected human carcinogen).
    EU-OEL: 0.1 mg/m3 as TWA; (skin).
    MAK: carcinogen category: 2; germ cell mutagen group: 2; sensitization of skin (SH); skin absorption (H)

    ENVIRONMENT
    This substance may be hazardous to the environment. Special attention should be given to fish.

    NOTES
    A severe intoxication is only likely after ingestion of large amounts. The following effects were reported: hallucinations, hypotension
    and convulsions.
    Depending on the degree of exposure, periodic medical examination is suggested.
    Do NOT take working clothes home.
    Long term exposure can cause skin peeling, rashes and acne-like dermatitis.
    Damage to the peripheral nervous system may cause reversible effects like unsteady gait, impaired speech, tingling sensations,
    incoordination, tremors of the hands and numbness of extremities.
    Other UN number for acrylamide solution is 3426, hazard class 6.1, packing group III

    ADDITIONAL INFORMATION
    EC Classification
    Symbol: T; R: 45-46-20/21-25-36/38-43-48/23/24/25-62; S: 53-45; Note: D, E

    All rights reserved. The published material is being distributed


    without warranty of any kind, either expressed or implied. Neither
    ILO nor WHO nor the European Commission shall be
    responsible for the interpretation and use of the information
    contained in this material.

    https://www.ilo.org/dyn/icsc/showcard.display?p_lang=en&p_card_id=0091&p_version=2 2/2

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