Name: Sherina Mae M.

Bolos Date: November 7, 2023

Year and Section: BSN-2C
Area: LR/DR C.I: Ms. Leah Bondoc

DRUG STUDY

NAME OF ROUTE, MECHANISM OF INDICATION CONTRA ADVERSE NURSING RESPONSIBILITIES

THE DRUG DOSAGE ACTION INDICA- EFFECT
AND TION
FREQUE
NCY
Generic Route: PO; Evening primrose  Cervical × Preterm Uterine Prior:
Name: TOP; It is oil (EPO) is often ripening: labor contractions:  Observe 10 rights of drug
Evening supported by used during Some risk: EPO is believed administration.
Primrose evidence that pregnancy due to women use Some to contain
Oil (EPO) EPO can also its potential to EPO in late people prostaglandins,  Before administering Evening
be stimulate uterine pregnancy believe which can Primrose Oil (EPO), it's crucial to
administered contractions. It (usually that stimulate uterine assess the patient's medical history,
Brand intravaginally, contains gamma- after 37 EPO can contractions. In current health status, and any
Name: as stated by linolenic acid weeks) to help some cases, this potential contraindications or
Eveprim Fairfax OB- (GLA), an help soften ripen the could potentially allergies to the medication.
GYN omega-6 fatty and ripen cervix lead to preterm
Associates in acid that the the cervix and labor or  Explain the purpose of Evening
Classification 2020. body can convert in the hope potentiall complications. Primrose Oil (EPO) and its potential
: into of y induce benefits during pregnancy, such as
Herbal Dosage: It is prostaglandins, promoting labor. Diarrhea and its role in reducing certain
Medicine, imperative which are labor. It is Therefor gastrointestinal symptoms.
Food that hormone-like believed e, using upset: Some
Supllement pregnant compounds that that EPO EPO in women may  Instruct the patient on the correct
Capsule. women take play a crucial role may help early experience dosage, timing, and duration of
500-2000mg in the regulation prepare the pregnan digestive issues, Evening Primrose Oil (EPO).
daily, starting of various cervix for cy may such as diarrhea
from the physiological childbirth pose a or nausea, when  Emphasize the importance of
38th week of processes, by risk of taking evening compliance with the prescribed
pregnancy, including promoting prematur primrose oil. regimen.
as there is inflammation and prostaglan e labor.
no uterine din It's Allergic  Discuss any potential side effects or
universally contractions. production. generall reactions: adverse reactions, and when to
accepted Prostaglandins y not Although rare, seek medical attention if they occur.
dosage. can help soften  Prevention recomm some individuals
the cervix and of ended in may be allergic
Frequency prepare the Preeclamp the first to evening
: 1 softgel uterus for labor. sia: Some and primrose oil, During:
cap once- However, it is studies second leading to skin
 Administer evening primrose oil
Name: Sherina Mae M. Bolos Date: November 7, 2023
Year and Section: BSN-2C
Area: LR/DR C.I: Ms. Leah Bondoc
tid-w/meals important to note have trimester rashes, itching, according to the prescribed route
, starting at that while EPO is suggested s. or swelling. (usually oral).
38 weeks. a popular folk that EPO
remedy, scientific may help × Allergie Bleeding risk:  Ensure the patient takes the
evidence on its reduce the s: If a Evening recommended dose as per the
effectiveness in risk of pregnant primrose oil healthcare provider's instructions.
inducing labor is developing woman might have a
limited and preeclamp is known mild blood-  Monitor patient’s vital signs
somewhat sia, a to be thinning effect, including BP and RR.
conflicting. Its pregnancy- allergic potentially
use during related to increasing the  Be vigilant for any signs of
pregnancy condition evening risk of bleeding, hypersensitivity or allergic
should be characteriz primrose which can be a reactions during and after
approached with ed by high oil or concern during administration.
caution, and blood any of its labor and
consulting with a pressure compon delivery. After:
healthcare and ents, its
professional is damage to use is Interactions  Record the administration of
advisable to other contrain with Evening Primrose Oil (EPO) in
ensure safety organs. dicated. medications: the patient's medical record,
and appropriate Evening including date, time, dose,
dosages. The  Pain relief: × Seizure primrose oil can route, and any specific
safety and EPO is disorder interact with instructions given to the
efficacy of EPO sometimes s: Some certain patient.
during pregnancy used to sources medications,
are still subjects alleviate suggest including blood  Note any patient responses or
of ongoing discomfort that thinners and adverse reactions to evening
research, and associated EPO anticoagulants, primrose oil (EPO).
healthcare with might potentially
guidelines vary conditions lower affecting their  Regularly monitor the patient
on its usage, like breast the effectiveness. for any signs of improvement
making it tenderness seizure or adverse effects related to
essential to , threshol Hormonal the supplement.
consider expert premenstru d in changes: EPO
advice and al people can affect
 If necessary, monitor
individual syndrome with hormone levels,
laboratory results, such as
circumstances. (PMS), and epilepsy which may not
relevant blood markers or
certain or other be advisable
nutrient levels, to assess the
References: pregnancy- seizure during
effectiveness and safety of
related disorder pregnancy, as it
evening primrose oil (EPO)
 Sim, T. F., & symptoms, s. could impact the
use.
Name: Sherina Mae M. Bolos Date: November 7, 2023
Year and Section: BSN-2C
Area: LR/DR C.I: Ms. Leah Bondoc
Sherriff, J. such as Pregnan delicate
(2018). Are breast pain t women hormonal  Continuously monitor vital
Herbal or uterine with balance required signs, especially if the patient
Medications cramps. such for a healthy experiences any adverse
Effective in condition pregnancy. effects that may affect their
Inducing  Skin s should overall well-being.
Labour? The health: be
Journal of Some cautious
Alternative people use when
and EPO to consideri
Complementa address ng the
ry Medicine. skin issues use of
like EPO.
 Hall, H. G., dryness or
Griffiths, D. L., eczema, × Interacti
& McKenna, which can ons
L. G. (2019). be with
Complementa exacerbate medicat
ry and d during ions:
alternative pregnancy Evening
medicine for due to primrose
induction of hormonal oil might
labor. Journal changes. interact
of Midwifery & EPO with
Women's contains certain
Health. gamma- medicati
linolenic ons, so
acid (GLA), it's
which is an essential
omega-6 for
fatty acid pregnant
that may women
support to
skin health. discuss
 Nipple its use
Pain and with their
Breast healthca
Health: re
EPO is provider,
sometimes especiall
used y if they
Name: Sherina Mae M. Bolos Date: November 7, 2023
Year and Section: BSN-2C
Area: LR/DR C.I: Ms. Leah Bondoc
topically are
on the taking
nipples to other
alleviate medicati
soreness ons.
or
discomfort. × Hor-
mone
 Evening sen-
Sickness: sitive
EPO has conditio
been ns: EPO
suggested contains
as a phytoest
remedy for rogens
evening that may
sickness impact
(nausea hormone
and levels.
vomiting Pregnan
during t women
pregnancy) with
. hormone
 Blood -
Pressure: sensitive
There is condition
some s like
anecdotal estrogen
evidence -
that EPO receptor-
can help positive
regulate breast
blood cancer
pressure. should
High blood consult
pressure their
during healthca
pregnancy, re
known as provider
preeclamp before
sia, is a using
Name: Sherina Mae M. Bolos Date: November 7, 2023
Year and Section: BSN-2C
Area: LR/DR C.I: Ms. Leah Bondoc
serious EPO.
condition,
so any use × Gastroi
of EPO for ntesti-
this nal
purpose discomf
should be ort:
under Some
medical individua
supervision ls may
. experien
 Prevention ce
of Perineal gastroint
Tears: estinal
EPO is discomfo
sometimes rt, such
used as
topically to diarrhea,
massage as a side
the effect of
perineum EPO.
in late Pregnan
pregnancy, t women
with the should
idea that it be
may aware of
reduce the this
risk of potential
perineal side
tearing effect.
during
childbirth. × Un-
The proven
evidence safety
for this is during
also pregnan
limited. cy:
While
 Anti- EPO has
Inflammat been
ory used by
Name: Sherina Mae M. Bolos Date: November 7, 2023
Year and Section: BSN-2C
Area: LR/DR C.I: Ms. Leah Bondoc
Properties some
: Evening pregnant
primrose oil women
contains to poten-
gamma- tially
linolenic ease
acid (GLA), sympto
which has ms like
anti- breast
inflammato tenderne
ry ss and
properties. premens
Some trual
women use syndrom
it for e, its
conditions safety
such as and
rheumatoid effective
arthritis or ness
skin issues during
during pregnan
pregnancy. cy are
not well-
establish
ed
through
rigorous
scientific
research
. This
lack of
conclusi
ve
evidence
is a
reason
to
approac
h its use
with
caution.
Name: Sherina Mae M. Bolos Date: November 7, 2023
Year and Section: BSN-2C
Area: LR/DR C.I: Ms. Leah Bondoc

References/Sources:

Sim, T. F., & Sherriff, J. (2018). Are Herbal Medications Effective in Inducing Labour? The Journal
of Alternative and Complementary Medicine.
https://www.ncbi.nlm.nih.gov/pmc/articles/
PMC6196873/

Hall, H. G., Griffiths, D. L., & McKenna, L. G. (2019). Complementary and alternative medicine for
induction of labor. Journal of Midwifery & Women's Health.
https://www.ncbi.nlm.nih.gov/
pmc/articles/PMC6881689/

Simpson M, Parsons M, Greenwood J, Wade K. Raspberry leaf in pregnancy: its safety and efficacy in
labor. J Midwifery Womens Health. 2001; https://pubmed.ncbi.nlm.nih.gov/11370690/

Beckmann MM, Garrett AJ.(2019) Antenatal perineal massage for reducing perineal trauma. Cochrane
Database Syst Rev. 2006;(1):CD005123.https://pubmed.ncbi.nlm.nih.gov/23633325/
Cameron I, Fraser IS. Amelioration of the premenstrual syndrome by treatment with a prostaglandin

synthesis inhibitor. Br J Obstet Gynaecol. https://pubmed.ncbi.nlm.nih.gov/6362715/

Horrobin DF. The roles of essential fatty acids in the development of pre-eclampsia and other conditions.

Prostaglandins Leukot Essent Fatty Acids. https://pubmed.ncbi.nlm.nih.gov/3047752/

Lowes, C., & Wallace, J. (2017). Gamma-linolenic acid. StatPearls [Internet]. Available from

https://www.ncbi.nlm.nih.gov/books/NBK534848/

Huntley, A., & Ernst, E. (2002). A systematic review of herbal medicinal products for the treatment of
Name: Sherina Mae M. Bolos Date: November 7, 2023
Year and Section: BSN-2C
Area: LR/DR C.I: Ms. Leah Bondoc

menopausal symptoms. https://pubmed.ncbi.nlm.nih.gov/14501609/

Franco, O. H., Bonneux, L., de Laet, C., Peeters, A., Steyerberg, E. W., & Mackenbach, J. P. (2004). The Polymeal:

a more natural, safer, and probably tastier (than the Polypill) strategy to reduce cardiovascular disease by

more than 75%. https://pubmed.ncbi.nlm.nih.gov/15604180/

PubMed Health. (2017). Evening primrose oil.

https://www.ncbi.nlm.nih.gov/pubmedhealth/PMHT0012673/?

report=details#side_effects

Reference: McGregor, J. A., & French, J. I. (1997). Uterine contractility and the effect of evening primrose oil.

Journal of Reproductive Medicine, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9947258/