Scribd Logo
Upload

Welcome to Scribd!

  • 41 views

    Amines

    Uploaded by

    Mann Dutiya
    1. The document discusses methods for synthesizing various amines, including by the reaction of alkyl halides with ammonia or other amines. 2. Common reactions include the reduction of nitro compounds to amines using metal catalysts, and the Gabriel synthesis which involves reaction of a phthalimide salt with an alkyl halide. 3. Carbylamines can be synthesized by reaction of alkyl halides with sodium amide followed by hydrolysis, producing a primary amine.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd

    Amines

    Uploaded by

    Mann Dutiya
    41 views6 pages
    1. The document discusses methods for synthesizing various amines, including by the reaction of alkyl halides with ammonia or other amines. 2. Common reactions include the reduction of nitro compounds to amines using metal catalysts, and the Gabriel synthesis which involves reaction of a phthalimide salt with an alkyl halide. 3. Carbylamines can be synthesized by reaction of alkyl halides with sodium amide followed by hydrolysis, producing a primary amine.

    Original Title

    Amines - Copy (4)

    Copyright

    © © All Rights Reserved

    Available Formats

    PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    1. The document discusses methods for synthesizing various amines, including by the reaction of alkyl halides with ammonia or other amines. 2. Common reactions include the reduction of nitro compounds to amines using metal catalysts, and the Gabriel synthesis which involves reaction of a phthalimide salt with an alkyl halide. 3. Carbylamines can be synthesized by reaction of alkyl halides with sodium amide followed by hydrolysis, producing a primary amine.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    41 views6 pages

    Amines

    Uploaded by

    Mann Dutiya
    1. The document discusses methods for synthesizing various amines, including by the reaction of alkyl halides with ammonia or other amines. 2. Common reactions include the reduction of nitro compounds to amines using metal catalysts, and the Gabriel synthesis which involves reaction of a phthalimide salt with an alkyl halide. 3. Carbylamines can be synthesized by reaction of alkyl halides with sodium amide followed by hydrolysis, producing a primary amine.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    of 6

    Page No.

    Date
    qL Lo 22

    13AMTNES

    acnnoaolusis ot alk balide


    aAa alky halide o
    Xcess heated alcaal coluhina
    omnnia he hologen
    au NH ahomseplaceso
    -X NHCale). A R-NH
    alkylbalide CexceSs)
    1omiae

    The Ordec ot xeachvty ot alkq


    hase d amni
    - T 2 R-r 2 R-CL

    4Reduchba atam.com.@unnls
    Hhabc ano omonahr nitmcompouno can be reduce sl
    n maru amines lau ssin metal adi mixiuce SalHcl
    o Fe L hi

    R-No 6[HI R-NH2+2 Ha O

    Relsboa a alk cuaade

    nA amnoCan e abiaae b he Yeeuchoo o alk


    aide Sodim andl uene hs is Knoon aendu
    col hon
    Payo No.

    NGMr ohS ? - CHa NH


    R-CEN [HI aminc

    alesR-C=O-
    NH,
    coluchonhoa ol
    uch on
    achenLOih LIAIH o cd
    i n ox eles on

    OY MSoYn

    CH 3-CH2 - NH
    Cha-C NH2 t+ AHINalGMe Co-1

    1Gabrie t phihalnicle cntetis


    Thismefheed seo for prepe a hon of man
    amide
    22 involes aoses
    a)fomahon of potasium SaH ot me
    phthalimidle en phialimidc
    sith aleokolic koH

    Reacho.a 0

    O NH N:

    eT mahon G N- aik,l. phthalianJe_ irow.


    1he otiaqiumsalt by eahoA ih Qlk
    lide
    Date

    NH

    N-R

    N-alk oibalimide
    cAlal9ae kadnlysis aa) NaOH of N-

    cONG
    - NOH
    R-NH
    ONa
    LSodivm phthalate|
    L
    FHOEMnAn eancinem.ent ldegvaclahoa

    metano se cometAmele inn gångm


    amfoeCondainia ode canclannLess

    Lamne ana CoACen adeo) laq koH So luboa.


    O

    - NH r tcbHG R-NH 2kR.

    Caap le
    CH NM2+ +4koH CM3NH2+2k K Cob,
    2Ht 20
    Page No

    h?cal oro Drvhie ot a n

    hovahrn n tec

    ae

    osic Compouvd
    oioe ore
    Ye
    uot2,_ Coluhon Dm tmy
    heeOe

    amnes HOmon Cz heushye _auksla ha


    f l a hon_ c

    Omine
    alk halide aue omitt Ot Secandan
    hmo
    amia teham amine alone t h A e t r o alkl mmomlur
    Lade

    NH2 , Nit HX

    t o monn imînaho

    hen etn.alkl mmbniun Lileskeated s


    S ey Oiole e Quanderna -AmMOauM
    ydho xiole Quonde rmam ammoni um asalno aiole_on_
    frDn heahnt udetoek oetaelnenhon h iea
    C kens Colleo a lomgnn ( elinenahon
    (H2

    a OH AazO|cHn"cH,-Ch, N -(2C
    C CH Cr 3
    Page No.
    Date

    HaCH2-CHa N-(Ha CH3 CH2


    CH2-C3

    Caxbylamne cachoo

    hcaa L cioofor

    - NH +CHC13 3koH 9-N¢i zkcl+ 3H-0


    Aksocmide)
    eac b'on Ath ditous ocio

    HIphak nsn amnes on eacho.o Lth tou


    oms phabc ollazoniu Salt

    -NHn t HNoa 2a3KA2736 2 -Nac


    alkl dio2onium
    cHorde]
    HaO 2-oH 4N1+
    HC

    Sypmha hon

    eactsLth bmmine a Dom emtre hur


    avea htc efuste o 2,4,6 -rlbmbgrln
    3H
    O+9Br

    Nsabioo

    +(on H,9
    conc HNos
    22k

    N
    NO2

    ulonahoo
    NH2 NHoHSO4

    H So4

    NH

    SO3

    You might also like