uMR Modality Introduction

Business Management of Emerging Market

MAGNETIC RESONANCE
uPMR 790
3.0T
60 cm
uMR 780 uMR 790 32/48 CH
3.0T 3.0T
50/200 *
65 cm 60 cm
32cm AFOV for PET
32/48 CH 3.0T 32/48 CH
42/220 * 100/200 *

uMR 588
uMR 570 1.5T
1.5T
60 cm
70 cm
24 CH
uMR 560 24/48 CH 1.5T 33/125
1.5T 33/160 or 45/200 uMR 580
60 cm 1.5T
24 CH 60 cm
33/160 16 CH
*Gradient (FDA)
33/125
uMR 780 42/200
uMR 790 90/200
uPMR 790 45/200
 > 550 MR Installations Worldwide by Feb. 2019

1.5T > 450 Installations 3.0T > 100 Installations

since 2013 since 2015

2015- 1.5T Zhongshan Hospital ‘uCS acceleration not only improves the imaging speed, but also helps
2016- 3.0T Fudan University, China us transition from qualification to quantification, by precisely
2017- PET/MR capturing the dynamic flow of contrast media in liver.’
Prof. Meng-Su Zeng, director of radiology department

2014- 1.5T Chinese PLA General Hospital, ‘In term of image quality, acquisition technique and customer service,
2014- 1.5T Wide bore China uMR (UIH) achieves the same level of performance as other major
2015- 3.0T vendors. The stability of the applications and system fulfill all our
clinical needs.’
Prof. Lin Ma, director of radiology department

2016- 3.0T Peking University Third Hospital, ‘Peking University Third Hospital takes advantage of the magnet
2019-3.0T China homogeneity and uCS acceleration technique to set up a specific
imaging protocol for MSK study. By co-developing 24 channel Foot &
Ankle Coil, Peking University Third Hospital is able to provide 30cm
whole foot and ankle coverage, high SNR and fast imaging. ’
Prof. Hui-Shu Yuan, director of radiology department
> 550 MR Installations Worldwide by Feb. 2019

USA China
Morocco
> 500
Dominica Djibouti
Vietnam
Laos Philippines
Sri Lanka

South Africa
First uMR570 installed in USA

Memorial MRI &

Dignostics Imaging Centers
Zero He Consumption

Device report fro zero helium boil-

off

Zero Helium Consumption, 2 year

Market Performance

1.5T MR Market Trend in China by Unit 3.0T MR Market Trend in China by Unit
1200 400
1141
350 353
3
1000 990 312
83
300 301
1
280
800 820 61

711 743 230

158 250

142 134
227
2
600 235 200 119
54
93 223 104
141 177
1
69 217 150 40
57
400 195
155 163
233 51
100 103
231 108
200 200 89
214 194
50 76
215
82 102 128 25 27 45
0 59 0 9
2014 2015 2016 2017 2018 2015 2016 2017 2018
UIH GE Siemens Philips Others Total UIH GE Siemens Philips Others Total

Market data from IPSOS

Core MR Technologies Designed by United Imaging

In-house Research, Development and Manufacture of Core Components

Superconducting RF RF coils
magnet components

Gradient Spectrometer Software

End to end coverage

System
Hardware End to end coverage
• Service continuity
Imaging Operating
Workflow Software • System liability
• Cost efficiency
• Potential for advancement
Reconstruction
&
Receiver
Post-processing Coils

Applications
Beckett3

Routine MR workflow
Diapositive 11

Beckett3 基本知识普及⼀下
zheng.zhang_MR; 31/07/2018
Workflow-Radiology Department
Safety Issue
To ensure safety, patients and support staff should be thoroughly screened for metal
objects prior to entering the scan room. Often, however, patients have implants
inside them that make it very dangerous for them to be in the presence of a strong
magnetic field. These include:

•Metallic fragments in the eye, which are very dangerous as moving these
fragments could cause eye damage or blindness
•Pacemakers, which may malfunction during a scan or even near the machine
•Aneurysm clips in the brain, which could tear the very artery they were
placed on to repair if the magnet moves them
•Dental implants, if magnetic

Most modern surgical implants, including staples, artificial joints and stents are
made of non-magnetic materials, and even if they're not, they may be approved for
scanning. But let your doctor know, as some orthopedic hardware in the area of a
scan can cause distortions in the image.

https://science.howstuffworks.com/mri6.htm https://www.ipem.ac.uk/ScientificJournalsPublications/MRIS
afetyNotices/MRISafetyNotices-AmericanVersions.aspx
Workflow-Hardware
 1.5T RF Surface Coils
Full suite of RF surface coils to your clinical needs UIH exclusive

Head & Neck Coil - 16 Spine Array Coil- 24 Body Array Coil – 6 Flex Coil -4 Body Array Coil – 12

Shoulder Coil - 12 Knee Coil - 12 Wrist Coil - 12 Small Loop Coil-1 Breast Coil – 10

Foot & Ankle Coil - 24 Temporomandibular Joint Coil - 4 Acupuncture Head Coil – 12
Cardiac Coil - 24 Lower Extremity Coil - 24
Driven by better workflow: Temporomandibular Joint Coil

TMJ coil
• 4 independent RF elements
• Super easy to use
• Soft and fit for users
• Superb image quality

Close mouth Open mouth

Innovation in Musculoskeletal imagin

Foot & Ankle Coil

• 24 independent RF elements
• 3-direction Parallel Imaging
• High Resolution with Excellent FatSat
• Large coverage for foot and ankle
PDWI_FS
FOV 300*300mm
Voxel size 0.33*0.33*3mm
2:30
PDWI_FS
FOV 220*220mm
Voxel size 0.5*0.85*3mm
2:19

Foot & Ankle Coil 24-ch 8-ch Foot & Ankle Array Coil (Other Vendor)
Driven by TCM: Acupuncture Head Coil

Acupuncture Head Coil

• 12 independent RF elements
• Space designed for acupuncture
• Soft and fit for the shape of the head
• Superb image quality

Acupuncture coil-12 Head neck coil -16

 1.5T Modality Coils uMR 570 uMR 580 uMR 588
Head & Neck Coil -16 √ √ √
Spine Coil - 24 √ √ √
Standard Configuration Body Array Coil - 6 √ √ √
Flex Coil Large - 4 √ √ √
Flex Coil Small - 4 √ √ √
Body Array Coil - 12 √ × ×
Breast Coil - 10 √ √ √
Knee Coil - 12 √ √ √
Optional Configuration Lower Extremity Coil - 24 √ √ √
Shoulder Coil - 12 √ √ √
Wrist Coil - 12 √ √ √
Small Loop Coil -1 √ √ √
Cardiac Coil – 24 10.2019 × 10.2019
not volume production，will
Foot & Ankle Coil - 24 7.2019 × 7.2019
provide H2 2019
Temporomandibular Joint Coil - 4 10.2019
 Workflow-Hardware

Bore size, 60, 65, 70cm Digital display panel (DDP) Alarm Box Vital signal monitor (VSM)
• Cater for big size patients • patient information • System on& off • wireless
• Benefit for off-center examination • physiological signal • Magnet Quench • Patient monitoring
• Environment adjustment • ECG gating
• operator guide • Respiratory triggering
Digital display panel (DDP)

•patient information
•physiological signal
MR_DDP •Environment adjustment
•operator guide
Patient communication system

Emergency stop
Lock the table
Stop scan

Alarm ball headphone Intercom system on control room

Software

Patient Administration, PA Patient Register, PR EXAM

Review-2D Review-3D Review-Fusion

Provides a patient-centric exam
Protocol
uMR Examination

Features
• Parallel workflow
• User friendly
• Real time reviewing
• Physiological signal
Image Review

Functions
• Sequence compare
• ROI setting
• Annotation
• Movie
Filming / PACS

Functions
• Film printing
Special features: Drag-on (image->protocol)
Special Feature: Protocol Compare
Beckett2

Application Package
Comprehensive Portfolio of Applications

Neuro Spine Body Vessel MSK Cardiac

SWI+ DTI MRS BOLD uCS FACT

Application Package

Neuro imaging

Body imaging

Cardiac & Angiography

Musculoskeletal imaging

Breast imaging
Routine Head Imaging

TR/TE :1895/12.5
TI:825
0.65*0.81*6mm TR/TE 7500/91
1:58 0.72*1.03*6mm
2:38
T1W_FLAIR
T2_FLAIR_FS

DWI
T2W_ARMS TR/TE 2211/89.9
TR/TE: 4644/127 b0,b1000
0,.65*0.65*6mm 1.6*1.5*6mm
1:33 1:02
Diffusion Weighted Imaging (DWI)

DWI b0 DWI b1000 ADC

• Sub-acute cerebral infarct

SWI(susceptibility weighted imaging)

T2_FSE

• Very sensitive for

detecting micro
bleeding or calcification

T1_FLAIR SWI_MinIP
Isotropic gre_fsp_3d T1 imaging
ARMS

arms K-space t2_fse_tra t2_arms_tra

• arms (acquisition and reconstruction with motion suppressions)

• Reduce motion artefact via radial k space acquisition
• Very useful for paediatric or elderly patients
Spine imaging
Whole-spine 3D

Matrix 3D T2WI Matrix 3D T1WI

Pixel size:1.17*1.17*1.28mm Pixel size:1.17*1.17*1.28mm
Scan time:5:40 / bed position Scan time:6:13 / bed position
Integrated Coil Solution
Brachial & Sacral Plexus

Matrix 3D T2WI Matrix 3D T2WI

TR/TE: 3600/435ms TR/TE: 3500/522ms
Scan time: 4:51 Scan time: 4:38
No Contrast Enhanced No Contrast Enhanced

uMR770
 neck

T1_FSE T2_FSE
stir

T2_FSE T1_GRE_FS
uMR770 T1_FSE
thorax

DWI
ADC on Lesions =0.9*10-3mm2/sec Dynamic contrast enhancement (DCE): Scan time:4.8sec,80 phase s
abdomen

Quick3d nce t1_quick3d_fs +C 20s t1_quick3d_fs +C 50s t1_quick3d_fs +C 80s

DWI_b0 DWI_b500 ADC T2_ARMS_BH

uMR770
Free-breathing liver scan: Radial3d

Quick3d-fb Radial3d-fb
Uterus

T2 FSE with Fatsat TRA DWI with b=800

T2 FSE SAG
uMR570 T1 FSE TRA
Courtesy to Zhongshan Hospital, Fudan University
Prostate
Pi-RADS score 5

B 50 b 800 b 1500 ADC

Application Package

Neuroimaging

Body imaging

Cardiac & Angiography

Musculoskeletal imaging

Breast imaging
Cardiac - Morphology

T1 sax T1 4ch T2 sax T2 4ch

T2 4ch T2 4ch FS T2 STIR T2 STIR

Cardiac - Function

Radial bSSFP
+ echo sharing
+ retro Cine

Real-time
tFAST

uMR770
 Cardiac – Perfusion and delay enhancement

LV Blood pool
Time-Intensity Curves

[Gd]

Infarcted Myocardium

Contrast
Injection

Normal Myocardium
Time
< 1 min > 10 min
uMR770
First-Pass Delayed Enhancement
Time of flight (TOF) imaging

TOF 3D

TOF 3D
aneurysm
MR Venography (MRV)

TOF 2d MRV Phase Contrast (PC) 3d MRV

uMR570
carotid CE-MRA

TR/TE/FA: 3.35/1.35/25
pixel size: 1.2*0.9*1.7mm
Scan time: 18.6
Abdomenal CE-MRA

400mm

Abdomenial aorta, Renal artery

TR/TE/FA: 3.2/1.2/25
pixel size: 1.4*1.25*1.25mm
Scan time: 14s
Peripheral CE-MRA
Application Package

Neuroimaging

Body imaging

Cardiac & Angiography

Musculoskeletal imaging

Breast imaging
MSK

uMR570
MSK-3D

Matrix 3D
Voxel Size:0.4*0.4*0.4
Time: 6:36

Anterior Cruciate Ligament Posterior Meniscofemoral Ligament

uMR770
 Big FOV

440mm

T1WI-COR T2WI-COR-FS
Matrix 290×512 Matrix 293×512
FOV 360×440 Time 1min02s Time 1min56s
 MRA( MR Arthrography)

T1WI-COR-FS
Matrix 345×480
T1WI-AXI-FS Time 2min28s
Matrix 345×480
Time 2min28s

T1WI-ABER-FS
T1WI-SAG-FS Matrix 345×480
Matrix 345×480 Time 2min28s
Time 2min28s
Application Package

Neuroimaging

Body imaging

Cardiac & Angiography

Musculoskeletal imaging

Breast imaging
Breast

STIR STIR T1w Quick 3D STIR SAG

SAG

Quick 3D Dyn T1W Quick 3D DYN PEI

High resolution
1.5T Clinical
Highlights
Advanced Applications

• Stitching
• MRS Analysis
• MAPs
• Breast Evaluation
• United Neuro
• Brain Perfusion
• Vessel Analysis
Advanced Applications---MRS Analysis

Single Voxel Spectroscopy

(SVS)

Chemical Shift Imaging

(CSI) (WIP)
Advanced Applications---MRS Analysis

T2WI
Lesions Contrailateral region
15*20*25mm 15*20*25mm
TR/TE:2000/144 TR/TE:2000/144
NSA:128 NSA:128
Scan time:4:21 Scan time:4:21
Advanced Applications ---Functional MRI

EPI or SMS Time course

Visual Cortex FDR correction, p = 0.05

Statistic map Motion correction

p = 0.05, FWE correction
BOLD fMRI on right finger tapping Auditory Cortex *SPM results
Advanced Applications ---Diffusion Tensor Imaging (DTI)

Fiber tracking
Advanced Applications --- Brain Perfusion

Motion correction , remove background、auto select AIF and parameter map.

Provide rCBV rCBF MTT TTP
Advanced Applications --- Stitching
Advanced Applications— Maps
Advanced Applications ---breast evaluation
Advanced Applications ---Vessel Analysis
Product Positioning & Selling Points
33mT/m; 160T/m/s 45mT/m; 200T/m/s
Big Bore
More comfortable

Best Homogeneity in the Industry

Better Image quality

Intuitive Workflow
Save time for patient & doctors

Comprehensive Application Solution

Easy diagnosis
Magnet uniformity and FOV

high-homogeneity magnet results in better fat Devices with insufficient

saturation and large image area. magnet homogeneity and
FOV
 Product compare uMR 570
UIH GE SIEMENS PHILIPS
Model uMR 570 Optima MR450w Magnetom Aera Ingenia 1.5T Omega

Patient Bore 70 cm 70 cm 70 cm 70 cm
Magnet uniformity（50cm DSV） 0.831 ppm 3.3 ppm 3.1 ppm 5 ppm
Magnet uniformity（45cm DSV） 0.246 ppm 1.2 ppm / 1.1 ppm
Magnet uniformity（40cm DSV） 0.101 ppm 0.5 ppm 1.1 ppm 0.5 ppm
Magnet uniformity（30cm DSV） 0.033 ppm 0.11 ppm 0.2 ppm 0.15 ppm
Magnet uniformity（20cm DSV） 0.013 ppm 0.035 ppm 0.06 ppm 0.05 ppm
Magnet uniformity（10cm DSV） 0.003 ppm 0.007 ppm 0.01 ppm 0.015 ppm
XJ: 33 mT/m 33 mT/m
X/Y/Z-axis gradient field strength 45 mT/m 34 mT/m
XQ: 45mT/m HP: 45mT/m
XJ: 125 T/m/s 120 T/m/s
X/Y/Z-axis gradient system slew rate 200 T/m/s 150 T/m/s
XQ: 200T/m/s HP: 200T/m/s
RF receiver channels 24/48 16/32 24/48/64 N.A

Copyright @Shanghai United Imaging Healthcare Co. Ltd Confidential. For internal use only.
Intuitive workflow
Comprehensive Portfolio of Applications

Neuro Spine Body Vessel MSK Cardiac

SWI+ DTI MRS BOLD uCS FACT

Big Bore
More comfortable

Best Homogeneity in the Industry

Better Image quality

Intuitive Workflow
Save time for patient & doctors

Comprehensive Application Solution

Easy diagnosis
uCS Technology
Up to 16 times acceleration

Intuitive Workflow
Save time for patient & doctors

Economic Success
Increase productivity

Comprehensive Application Solution

Easy diagnosis
Intuitive workflow
Comprehensive Portfolio of Applications

Neuro Spine Body Vessel MSK Cardiac

SWI+ DTI MRS BOLD uCS FACT

uCS Technology
Up to 16 times acceleration

Intuitive Workflow
Save time for patient & doctors

Economic Success
Increase productivity

Comprehensive Application Solution

Easy diagnosis
Product compare UIH 1.5T
Model uMR 588 uMR 580
Time to Market 2018 2018
Patient Bore (cm) 60 60
Liquid Helium Capacity (L) 850 850
CS technology uCS ×
Z-axis FOV (cm) 50 50
Gradient strength (mT/m) 33 33
Slew rate (T/m/s) 125 125
RF receiver channels 24 16
Homogeneity@40cm DSV (ppm) 0.45 0.45
Homogeneity@30cm DSV (ppm) 0.04 0.04
Homogeneity@20cm DSV (ppm) 0.02 0.02
Homogeneity@10cm DSV (ppm) 0.003 0.003
0

Intuitive Workflow
Save time for patient & doctors

Economic Success
Increase productivity

Comprehensive Application
Solution
Easy diagnosis
42/220
220
42mT/m; 220T/m/s