Gigantism
Gigantism
Gigantism
10 – STE
GIGANTISM
Gigantism is a rare condition that occurs due to an excess of growth hormone (GH)
during childhood, leading to excessive growth and unusually tall stature. It is a type
of acromegaly, a condition characterized by the overproduction of GH after the
growth plates have closed, which results in the enlargement of the bones of the
hands, feet, and face.
The most common cause of gigantism is a benign tumor of the pituitary gland, which
secretes excess GH. Other causes include genetic mutations that affect the GH
signaling pathway, or an abnormal response of the body to GH.
The effects of gigantism vary depending on the severity and duration of the
condition. Some common effects include increased height, enlarged hands and feet,
joint pain, muscle weakness, and vision problems. In severe cases, gigantism can
lead to serious health problems such as heart disease, diabetes, and arthritis.
Gigantism is a fascinating and rare condition that has significant implications for
affected individuals. It highlights the importance of understanding the complex
interactions between hormones, genetics, and environmental factors in human
development and health. Further research into the mechanisms underlying gigantism
could potentially lead to new treatments and improved quality of life for those
affected by this condition.