0 MetaboAnalyst 5.0 Overview

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MetaboAnalyst 5.

0
-- a web-based platform for streamlined
metabolomics data analysis

2022-07-12
A long way to towards version 5.0
Key Focus Details
1.0 Statistical analysis for targeted Focused on data processing, normalization and statistical analysis of
metabolomics metabolomics data;

2.0 Functional analysis for targeted Added metabolite set enrichment analysis (MSEA) and metabolic
metabolomics pathway analysis, as well as two-factor and time-series analyses.

3.0 Translational applications Added biomarker analysis, power analysis, and joint-pathway analysis.
Completely updated the web interface

4.0 Global metabolomics and Completely revamped web framework for scalable performance, with
reproducible analysis three new modules (MS peaks to pathways, biomarker meta-analysis,
and network explorer), together with a companion R package
(MetaboAnalystR)
5.0 Big data analytics - from raw Leveraging local server - public cloud - user browsers to deliver end-
spectra to functional insights to-end metabolomics data analysis, with support for spectral
processing, comprehensive functional analysis and meta-analysis.
Users can now switch between compatible modules, better graphics
….
User Traffic (Google Analytics)

From 200 users/month to 15,000


users/month

>3.5 million jobs submitted from


>100,000 users in the past 12 months
Design Concept (under the hood)

Divide & distribute Engaging &


On-demand computing
computing empowering users
Help Us Help You
Before you contact,
• Have you read the Data Format and Tutorials?
These resources provides detailed explanations for common questions received from users. Please first go through these
resources as listed on the left bar.

• Have you tried to use OmicsForum for some answers?


OmicsForum (www.omicsforum.ca) is a newly launched platform for users to communicate and share experience when
they are doing omics analysis with any tools from our team. FAQs of MetaboAnalyst are provided there and updated
more frequently.

• Have you tried our example data to see if the issue still exists?
Most of the time, the issue is related to improper data format. Although we try to give informative error messages during
data uploading, there are always exceptions. If our example works, download and examine our example datasets to get
better idea

• Did you provide enough details so that the issue can be reproduced?
Remote troubleshooting requires more information in order to figure out the exact cause of the issue. Please
• Indicate which example data you used, or provide a copy of your data;
• Document all steps leading to the issue. Sometimes screenshots may be necessary
Acknowledgements
New Tutorials for MetaboAnalyst 5.0

1. MS Spectral Processing
2. Functional Analysis (MS Peaks)
3. Meta-Analysis (MS Peaks)
4. Joint Pathway Analysis
5. Enrichment Analysis
6. Network Explorer ①
7. Statistical Analysis ② ③
[metadata table]
⑤ 

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