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I
ABSTRACT
This study would be conducted on Jimma University on Statistical Analysis on the Awareness of
Jimma university under graduate students towards blood donation; the case study of college of
natural science . To meet this we would collected the data by using self-administered
questionnaire, which is distributed to the respondents. The sampling tehnique is stratified random
sampling we classify strata based on their department we have seven strata.We can collect data
by simple random sampling; we have taken the representative sample n=92 from the study
population N=1654. The study would used chi-square test of association the variable age, health
status, residence area and interest of individual have significant association and binary logistic
regression. In this study the variable, residence area and interest of individuals on blood
donation have significance on the awareness of students.
II
Table of Contents page
Acknowledgment.............................................................................................................................I
Abstract...........................................................................................................................................II
Chapter One.....................................................................................................................................1
1 Introduction...................................................................................................................................1
1.1 Background of the study............................................................................................................1
1.2Statement of the problem............................................................................................................3
1.3 Objectives..................................................................................................................................3
1.3.1 General Objectives.................................................................................................................3
1.3.2 Specific Objectives.................................................................................................................3
1.4 Signifcance of the study............................................................................................................4
1.5 Limitation of the study..............................................................................................................4
Chapter Two.....................................................................................................................................5
2. Literature Review.........................................................................................................................5
2.1 Blood donation...........................................................................................................................5
Chapter Three...................................................................................................................................9
3. Methodologies .....................................................................................................................9
3.1 Study area..................................................................................................................................9
3.2 Source of population..................................................................................................................9
3.3 Study population .....................................................................................................................9
3.4 Study design.............................................................................................................................10
3.5 Sources of data type.................................................................................................................10
3.6 Data collection instrument.......................................................................................................10
3.7 Sampling technique and sample
size .determination.............................................................................................................................
...10
3.7.1 Sample size determination...................................................................................................10
3.7.2 sampling technique...........................................................................................................,...11
3.8 Study variables...................................................................................................................,....12
3.9 Methods of data analysis......................................................................................................,...12
3.9.1 Descriptive statistics..........................................................................................................,..13
3.9.2 Inferential statistics...........................................................................................................,..13
3.9.2.1 Logistic Regression.......................................................................................................,....13
3.9.3 Binary logistic regression...........................................................................................,.........13
3.9.4 Chi-square test of independence.....................................................................................,....14
Chapter four.....................................................................................................................,.............16
III
4.1 Descriptive statistics................................................................................................................16
4.2 inferential statistics..................................................................................................................19
4.2.1 chi-square..............................................................................................................................19
4.2.2 bnary logistic regression.......................................................................................................20
4.2.2.1 odds ratio interpretation.....................................................................................................21
4.2.2.2 Goodness of fit...................................................................................................................21
4.3 Discusion..................................................................................................................................22
Chapter five....................................................................................................................................23
5 conclusion.and
recommendation.............................................................................................................................23
5.1 conclusion................................................................................................................................23
5.2 recommendation.............................................................................................................,,........23
Reference.......................................................................................................................,...............24
Appendex.........................................................................................................................,,............25
VI
CHAPTER ONE
1. INTRODUCTION
Donated blood includes red blood cells and the other things that make up the blood, such as
platelets and plasma. Blood that contains all the parts is called whole blood.
You can donate blood at American Red Cross clinics or other clinics or blood banks. You may
be able to donate during blood drives at your workplace.
About 1 pint (480 mL) of blood is taken when you donate. It takes about 10 minutes. The whole
process including answering questions and having a short exam takes up to an hour.
Donated blood is tested to make sure that it is safe to use. It's also checked for its type. This
makes sure that the person who needs blood gets the right type.
Be at least 17 years old. (In some states, you can donate if you are 16 years old and get
permission from a parent.)
Weigh at least 110 lb (50 kg).
Be in good health.
Some people can't donate because of health or other issues. For example, you may not be able to
donate if:
Having a long-term illness, such as diabetes, doesn't mean you can't donate. You may be able to
give blood if your health problem is under control. But you shouldn't donate blood if you feel
like you're getting a cold or the flu.
Before you donate, a health professional will ask about your current and past health to make sure
that you can donate. Some of these questions are very personal, so you will be asked them in
private. You will be asked these questions every time you give blood, because the list of who can
give blood may change, or your health may change.
Make sure you feel good. Don't give blood if you feel ill.
Eat a good breakfast or lunch. But avoid fatty foods. They can affect some of the tests
done on donated blood to make sure it's safe.
Drink plenty of fluids.
Get plenty of sleep the night before.
Blood transfusions form a crucial and irreplaceable part in the medical management of many
diseases. The collection of blood from voluntary, non-remunerated blood donors from low risk
populations is an important measure for ensuring the availability and safety of blood transfusion.
In a state like Uttarakhand which is visited by lakhs of visitors during pilgrimage season and
where natural calamities and accidents are very common, the availability of blood is of utmost
importance.
In the Soviet period, the blood donation system operated in Lithuania exclusively on a
remunerative basis. After joining the EU, Lithuania committed itself to meeting the EU
requirements to provide all consumers within its boundaries with safe blood products made from
voluntary unpaid blood donations. However, the introduction of a non-remunerated donation
system may considerably affect donors' motivation and retention. Thus the aim of the current
research was to determine blood donation motives among the present donors and investigate
their attitude towards non-remunerated donation.
The Italian Twin Registry (ITR) has been carrying out several genetic-epidemiological studies.
Collection and storage of biological material from study participants has recently increased in the
light of biobanking development. Within this scenario, we aimed at investigating understanding,
awareness and attitude towards blood/DNA donation of research participants. About these quite
unknown dimensions more knowledge is needed from ethical and social perspectives.
1.3 Objectives
2.1Blood donation
Blood transfusions form a crucial and irreplaceable part in the medical management of many
diseases. The collection of blood from voluntary, non-remunerated blood donors from low risk
populations is an important measure for ensuring the availability and safety of blood transfusion
Efforts continue worldwide to establish and maintain sufficient numbers of regular, volunteer
blood donors to ensure an adequate and safe blood supply. The constant concern with being able
to meet the demands for blood is because of the fact that only a small percentage of the eligible
population actually chooses to donate blood on a regular basis and that a significant percentage
of eligible donors are deferred temporarily or permanently because of strict deferral criteria
Continuously being added in the name of blood safety (Custer et al., 2004; Riley et al., 2007).
At the same time, the demand for blood and blood products in most countries continues to
increase because of the rise in human life expectancy and the implementation of new and
aggressive surgical and therapeutic methods requiring large quantities of blood and blood
products (Provan, 1999; Gillespie&Hillyer, 2002; Currie et al., 2004; Greinacher et al., 2007;
Mathew et al., 2007).
The fragile balance between blood supply and demand forces blood banks to constantly search
for more efficient ways to recruit blood donors (Ferguson, 1996). The method each country
adopts to attract blood donors and to cover its needs in blood supplies varies as a function of its
socio-economic structure (Rouger&Hossenlopp, 2005).
According to data collected by the Ministry of Health, in the year 2005, there were 610 056
blood donations in Greece, of which 322 370 (52·84%) were provided by replacement donors
(RDs) who donated blood to cover the transfusion needs of relatives and friends and 270 534
(44·35%) by volunteer donors (VDs) who donated on their own initiative. A small number, 17
152 (2·81%), of donors belonged to the armed forces. This last group is highly motivated to
donate voluntarily as they are compensated with days off from duty. Despite these figures,
however, and the slight increase in blood donations in 2005 compared with previous years, 24
000 red blood cell units were imported from Switzerland to cover the national needs for blood.
There are a number of reasons why Greece, like many countries, would like to increase the
number of regular VDs. As stated above, the number of donations is insufficient to cover the
Demand leading to the importation of blood from abroad almost every year. Also, VDs are
generally associated with safer blood supplies in terms of transfusion-transmitted diseases
(Maniatis et al., 1994; Liu et al., 1998). In fact, the World Health Organization and the Council
of Europe recommend that blood and blood components should only be collected from
voluntary, non-remunerated repeat donors (Dhingra, 2002; Council of Europe, 2003). In turn,
blood donation systems that rely on volunteer blood donors who donate on a regular basis can
better manage blood supplies and schedule transfusions. Finally, it is inappropriate, from an
ethical point of view, that relatives of a patient in need of blood should, under emotional
pressure, be obliged to search for people willing to donate blood for their relative's transfusion
needs.
Thus, the effort of the blood donation system in our country has two goals:
(1) The overall increase of blood units collected to ensure self-sufficiency in blood supply and
(2) The conversion of RDs into regular, VDs to increase the safety and facilitate the management
of the available blood supply.
In many countries of sub-Saharan Africans (SSA), family and replacement donors are
predominant (Takpoet al., 2007), reaching over 70% of blood donor populations in most
instances. These are either relatives or friends of the family, and in some instances are
’undercover’ paid donors, brought in to cater for their relative's blood needs. Clearly, such
donors present a greater risk than voluntary, regular, non-remunerated blood donors (VNRBD)
and should be discouraged as much as possible. However, VNRBD are scarce in SSA, where
according to Tapkoet al., (2007) they represent less than 50% of blood donors in 15 countries of
the 38 investigated. WHO advocates for 80–100% voluntary donations and for the organization
of centralized transfusion (Takpoet al., 2007). Doing away with the family replacement donors
would be desirable but should not worsen the insufficient blood supply. Replacement donors are
in the majority because they are readily available and cheaper to obtain, whereas supply based on
a voluntary donor system is more expensive for many countries (Hensheret al., 2000; Allainet al.,
2004; Lara et al., 2007).
Some controversy exists about there being insufficient voluntary donations. Countries need to
find ways of maintaining sufficient blood supply and improving blood safety from the available
replacement donors. In brief, the reason why replacement donors remain the main source of
blood in SSA is that it costs less to procure and fits well with the African culture of extended
family support.
Looking at blood donors in West and Central Africa, reports indicate that there is some disparity.
For example, a multicentre survey in Africa (TayouTagnyet al., 2009) reported that family
donors constituted 70 and 74·5% in Mali and Cameroon, whereas they constituted less than 20%
in Cote d’Ivoire and Burkina Faso (Takpoet al., 2007). Interestingly, in the Southern part of
Africa, some countries have more than 80% VNRBD including South Africa (De Coning, 2004).
Nevertheless, others still use replacement donors to some scale. Interestingly, it has been clearly
documented in a recent review that donor recruitment, quality assurance systems and blood
distribution mechanisms are major contributors to the high costs of blood from centralized
transfusion centers, with the costs of blood in this system being about four to eight times more
expensive than blood from hospital-based systems which rely on replacement donors (Bates et
al., 2007). The sustainability of centralized voluntary donor systems and their compatibility with
the levels of healthcare resource that exist in poor countries needs to be thought through,
although the burden of patients' families finding replacement donors might exacerbate poverty
and an unsafe blood supply. Thus, the availability of blood in most health facilities depends on
the blood donor system operated there.
Donor Age:
Several studies within the African context suggest that the African blood donor is mostly young.
In Kenya, Rajab et al. (2005) reported a mean age of 28·9 ± 8·5 years among their blood donors;
in Burkina Faso, Nébiéet al. (2007) reported a mean of 28 ± 7·9 years. In other countries of
East/Southern Africa, the mean ages reported are less than 28 years in Mozambique and Uganda
(Cunha et al., 2007; Hladik et al., 2006). Furthermore, in Rwanda, TayouTagny et al. (2009)
observed that more than 75% are less than 30 years.
These mean ages are 10–15 years less than those observed in European countries. For example,
in 2003 the proportion of blood donors under the age of 35 was less than 50% in France,
Belgium and the United Kingdom, and less than 45% in Switzerland and Finland
(Lefrère&Rouger, 2006). This difference may be explained by the fact that the voluntary donor
programmes in Africa tend to be centered on secondary school and university students
(Mandisodza et al., 2006).
Donor Gender:
Most studies in Africa report a male dominance in blood donation programmes. Agbovi et al.
(2006) in Togo reported 61% of their donor population to be males; Nébiéet al. (2007) reported
71·2% in blood donors in Burkina Faso, whereas Allain et al. (2008) reported that 90% of 3801
Ghanaian donors were males. In the recent survey in Central, Western and Eastern francophone
Africa regions, all seven countries surveyed reported less than 30% females in their donor
population (TayouTagny et al., 2009).
Donor Motivation:
Successful strategies have been introduced in various region s to supplement blood supply and
improve safety. For example, the Club 25 concept in Zimbabwe, where teenagers 16 years and
above are encouraged to donate 25 times in their lifetimes, has increased voluntary units of blood
and forms a vital part of the National Blood Transfusion Service (Mvere, 2002). The club 25
requires very high standards of dedication which are not easily reached in most of our settings,
but should be encouraged as a good practice. In South Africa, it has been clearly demonstrated
that it is useful to create a younger donor base to groom these young people as donors of the
future and to create a culture of blood donation amongst young communities. Efforts are needed
to retain voluntary donors. Added safety relies essentially on repeat donations, and hence the
need for donor motivation to come back. In Ghana, a niche of repeat volunteer donors has been
generated with little expense by creating a socially acceptable environment at a local radio
station premises (Allainet al., 2008).
During the 4-year period reported (2003–2006), 60% repeat donations have been collected from
3801 donors. Consequently, the overall voluntary donor percentage increased steadily from
44·1% in 2003 to 62·4% in 2006, and the prevalence of viral markers decreased dramatically
(e.g. a two-thirds reduction in HBsAg prevalence). In Ghana, this program has demonstrated
that providing an environment that adapts to the local cultural background is effective not only in
recruiting first-time donors but also in generating repeat donations at low cost (Allainet al.,
2008).
CHAPTER THREE
3. METHODOLOGIE
3.1 Study Area
Jimma University (JU) is one of the leading higher education institutions in the country located
south west of Ethiopia at Jimma town. Jimma University College of Agriculture and Veterinary
Medicine (JUCAVM) was established in 1952 as Jimma Agricultural Technical School (JATS)
following the agreement signed between the United States of America and the Imperial
Ethiopian Government under the joint affiliation of Ethiopian Ministry of Education (MoE) and
the Oklahoma State University (former Oklahoma Agricultural and Mechanical College) for the
period between 1952 and 1956. From 1956 to 1968, the school was jointly administered under
the Ethiopian Ministry of Agriculture (MoA) and the Oklahoma State University. Following the
termination of the agreement with the Oklahoma State University, the school was under the
exclusive administration of the Ethiopian MoA for the period 1968 to 1979 and it was renamed
as Jimma Institute of Agriculture (JIA). From 1979 to 1990, the institute was under the
administration of Commission for Higher Education and the naming was once again tailored to
Jimma Junior College of Agriculture (JJCA).
At the end of 1990, the affiliation of the college was under the Higher Education Main
Department (HEMD) with a name Jimma College of Agriculture (JCA). In 1994, the college was
once again transferred back to the Ethiopian Ministry of Education (MoE) until the year 1999
that marked the amalgamation of Jimma Institute of Health Sciences (founded in 1983) and
Jimma College of Agriculture (JCA) as cofounders of Jimma University.
Cross sectional study would be conducted to collect all information from under graduate
students of college of natural science
no = 97
n=
n= = 91.16
n = 92
ni = *n
N = total population
n= , i = 1, 2,.......,7
n1 = *92 = 13.68 14
n2 = *92 = 10.4 10
n3 =
n4 = *92 = 14.90685
n5 = *92 = 13.96
n6 = *92 = 13.516
n7 = *92 = 11.84767 12
Department Ni ni
Mathematics 246 14
Physics 187 10
Biology 246 14
Chemistry 268 15
Statistics 251 14
sport 243 13
Total 1654 92
High Low
Sex of the
respondent
Male 38 29 67 72.8
Female 18 7 25 27.2
Total 56 46 92 100
18-21 25 6 31 33.7
Age of the
respondent
22-25 21 24 45 48.9
>=26 10 6 16
17.4
Total 56 36 92 100
Excellent 29 31 60 65.2
Total 56 36 92
100
Table 2 the chi square test of independent between the students’ awareness to on blood donation and
socioeconomic, demographic and health factor in JU on collage of natural science.
From the above Pearson Chi-Square table, the corresponding p-value of the
socioeconomic, demographic and health factors of sex and attitudes are greater
than α=0.05 level of significance. Then we don’t reject the null hypothesis. We
can conclude that the variable sex and attitudes have no significant association
between the awareness of the respondents towards blood donation. This shows
that the respondent’s awareness towards on blood donation did not affected by
the variable sex and attitudes.
From the above Pearson Chi-Square table2, the corresponding p-value of the
socioeconomic, demographic and health factors of health status, previous
residence area and interest of individuals are less than α=0.05 level of
significance. Then we reject the null hypothesis. We can conclude that the
respondent’s age, health status, previous residence area and interest of
individuals have significant association between the awareness of the students
Respondents towards blood donation. This shows the age, health status, previous
residence area and interest of individuals of the respondents did affect the
awareness towards on blood donation.
4.2.2 Binary Logistic Regression
From the above logistic regression table, the model of logistic for the level of awareness of the
respondent:
Log (p/1-p) =βo+β1sex (1) +β2age (1) +β3age (2) + β 4health (1) +β5health (2)+β6residence area (1) +β7interest (1) + β8attitudes(1)
Logit (p/1-p)=-2.904-.852sex (1) – 1.085age (1)+.285age (2)+0.488health (1) -1.17health (2)
+1.926residence area (1)+1.973interest (1)+1.003attitudes(1)
From the above logistic regression table the variables sex, age, health status and attitudes
towards blood donation have corresponding p-value is greater than α value and the variables
residence area and interest of individuals towards blood donation corresponding p-value is less
than α value. Therefore we conclude that the parameter of independent variables Sex, age,
attitude and health status have no significant effect on awareness towards on blood donation but,
the parameter of independent variables previous residence area and interest of individuals are
significant effect on awareness towards blood donation.
4.2.2.1The odds ratio interpretation
The estimated odds 6 .861 indicates that the students whose previous residence area was urban
for the effects of the awareness towards on blood donation who have high awareness was 6.861
times that of the student whose previous residence area was rural .
The estimated odds 7.194 indicates that the students interested for the effects of the awareness
towards on blood donation that have high awareness 7.194 times that of the student not interested
for the effect of the awareness towards on blood donation.
Sex, age, health status and attitudes of students are have no significant effect on the awareness of
students towards blood donation.
4.2.2.2Goodness of fit
1 4.347 8 .825
H0: the model fit is good
H1: the model fit is not good
From the above Hosmer and Lemeshow test the p-value greater than α (0.05) value so we fail to
reject H0 and we conclude that the model fitted is good .The greater p-value show we have a
good model in our case the model match (significant)
4.3 DISCUSSION
Among 92 students, 60.9% of the students have high level awareness towards blood donation
and 39.1% of the students have low level of awareness on blood donation (from A.M.U in 2011
done research among 96 sample 30% students have low level of awareness the remaining 70%
have high level of awareness).
Among 92 sample of students, 72.8% of the students was male and 27.2% of students was
female, 33.7% of the respondents was age between 18 &21 and 48.9% of the respondents was
age between 22& 25 and 17.4% of the respondents was greater than or equal to 26 ages,65.2% of
the students have an excellent health status and 28.3% of the students have good health status
6.5% of the students have poor health status ,47.8% of the students was previously lived in urban
area and52.2% of the students was lived in rural area as well as 58.7% of students have
interested to donate blood and 41.3% of students have not interested to donate blood, 56.5% of
students have positive attitudes towards blood donation , 43.5% have negative attitudes towards
blood donation.
In our study respondent’s age, health status, previous residence area and interest of individuals
have significant association between the awareness of the students towards blood donation (in
A.M.U 2011 age, previous residence area and interest of individuals have significant association
between the awareness of the students towards blood donation but not health status ). Attitude of
students have no association in our study but in Greece (Custer, 2004; Riley , 2007) have
significant association on blood donation
In our study independent variables Sex, age, attitude and health status have no significant effect
(in A.M.U interest, residence, age significant ) on awareness towards on blood donation but, the
parameter of independent variables previous residence area and interest of individuals are
significant effect on awareness towards blood donation in our study.
5.1 CONCLUSTION
The above result and discussion leads us to the following conclusions:
As analyzed, the independence between the level of awareness towards on blood
donation with sex, age, attitude and heath status have no significant effect on the
awareness of students towards on blood donation. This shows that the level of
awareness towards on blood donation is not affected by sex, age, attitude and health
status of students.
Generally from the analysis of chi-square test, the awareness towards on blood
donation is highly associated with respondent’s age, previous residence area health
status and interest of individuals on blood donation. Logistic regression shows that
awareness towards on blood donation is affected by interest of individuals on blood
donation and residence area of individuals.
5.2 RECOMMENDATION
From the comment and suggestion forwarded by the students and conclusion above we would
like to recommend as follow:
The college should advise (teach) about blood donation for students.
The students should make their mind free from saying blood donation is harmful.
The college and blood bank should have a time of penal discussion on how students
can donate blood freely.
The college should give an idea support and establish the blood donor clubs which are
actively participated related the available blood supply in the country.
REFERANCE
1. Alvarez-Ossorio L, Kirchner H, Kluter H, Schlenke P.(2000) Low ferritin levels indicate
the need for iron supplementation: strategy to minimize iron-depletion in regular blood
donors. Transfusion Medicine.
2. Cunha , 2007; Hladik et al., 2006
3. Custer B, Johnson ES, Sullivan SD, Hazlet TK, Ramsey ST, Hirschler NV, Murphy EL,
Busch MP. (2004) Quantifying losses to the donated blood supply due to donor deferral
and miscollection. Transfusion.
4. Custer et al., 2004; Rile, 2007
5. Danvey JR. (2004) Recruiting blood donors: challenges and opportunities. Transfusion.
6. Dhingra N. (2002) Blood safety in developing world and WHO initiatives. VoxSanguinis.
7. Dhingra, 2002; Council of Europe, 2003
8. Medicine.
9. Provan, 1999; Gillespie&Hillyer, 2002
10. Provan, 1999; Gillespie&Hillyer, 2002; Currie, 2004; Greinacher, 2007; Mathew, 2007).
11. Rouger&Hossenlopp, 2005
12. TayouTagny, 2009).
APPENDEX
Questionnaire
Dear respondent, this questionnaire is prepared to collect data on statistical analysis on the
awareness and attitude towards blood donation in JU in case of under graduate students in
collage of natural science. This questionnaire must fill by under graduate in collage of natural
science students. Your appropriate response is handy for the successful completion of the study.
Mark your answer in the box below (X) give your appropriate response to open ended questions
1) Sex: male Female
2) Age [18-21] [22, 25] >=26
3) Your health status: excellent good poor
4) Your previous residence area urban rural
5) Have you ever donated blood? Yes no
6) In question “5” If ‘no’ why?
7) What is your awareness level on blood donation? High low
8) Did someone ask you to donate blood? Yes no
9) If ‘yes’ in“8” who asked you? Friend’s parents workers of blood bank
10) Do you have interest to donate your blood? Yes no
11) In question “10”If ‘no’ how did you find out about the need to donate
blood?...................................................................................................
12) What is your attitude towards blood donation? Positive negative
13) If you want to donate blood, for whom do you donate? Family relatives (friends)
for anyone
14) Do you agree that money should be paid to donors? Yes no
15) In question “14” If ‘yes’
16) Do you think that blood donation is harmful to donors? Yes no do not know
17) In question’16’ if ‘yes’ why?.............................................................................
18) Do you think that the blood in the blood bank is safe? Yes no do not know
19) What do you think that when blood transfusion is necessary?
…………………………………………………………
20) Department………………………………………….
Parameter coding
rural 48 .000
no 38 .000
male 67 .000
ኢየሱስ ጌታ ነዉ
በብዙ መከራ ዉስጥ እግዚአብሔር ደረሰልኝ