Drug Study
Drug Study
Drug Study
DRUG STUDY
DRUG STUDY
minimize or during
prevent them. therapy.
Monitoring: Teach
patient to
Monitor patients recognize
for signs and and report
symptoms of low signs and
magnesium level, symptoms of
such as abnormal low
HR or rhythm, magnesium
palpitation, levels.
muscle spasms,
tremors, or
seizures. Advise
Monitor for patient to
therapeutic notify doctor
effect, adverse immediately
effects, changes if they have
in the client’s abdominal
condition. pain or
diarrhea.
Evaluation:
Evaluate for
therapeutic
response
(relief of GI
symptoms).
DRUG STUDY
Generic Name: Treatment of severe Diffuses into organism, Frequent: Systemic: Most serious adverse Hypersensitivity to Assessment: Inform patient that
Metronidazole anaerobic infection interacting with DNA Anorexia, nausea, dry reactions reported in metronidazole. assess for infection urine may be red-
when oral medication is causing a loss of mouth, metallic taste. patients treated with Pregnancy (first before and during brown or dark.
Trade Name: not possible is helical DNA structure Vaginal: Symptomatic metronidazole injection trimester with treatment
Flagyl contraindicated when and strand breakage, cervicitis/vaginitis, have been convulsive trichomoniasis), use of Assess for rash, Avoid alcohol,
immediate anti-aerobic inhibiting protein abdominal cramps, seizures, encephalopathy disulfiram within 2 wks, urticaria alcohol-containing
therapy is required. synthesis. uterine pain. , aseptic meningitis use of alcohol during preparations
Dose:
optic and peripheral therapy or within 3 Implementation: (cough syrups,
500mg
Occasional: neuropathy, the latter days of discontinuing obtain cultures elixirs) for at least
Systemic: Diarrhea, characterized mainly by before therapy 48 hrs after the last
Form: numbness
constipation, vomiting, Obtain baseline dose.
Intravenous Infusion or paresthesia of
dizziness, CBC, LFT.
erythematous rash, an extremity.
Route: Question for Avoid tasks that
urticaria, reddish-brown history of require alertness,
IV urine hypersensitivity to motor skills until
metronidazole, response to drug is
Drug Classification:
other established.
Antiprotozoas
nitroimidazole
derivatives (and Educate about the
Safe Dose Range: parabens with
1,000 to 1,500 mg/day possible adverse
topical). effect
DRUG STUDY
(ulceration/change mouth, face, lips,
of oral mucosa, tongue, or throat
furry tongue,
vaginal discharge,
genital/anal
pruritus)
Evaluation:
. Evaluate the
effectiveness of
drug therapy.
DRUG STUDY
Generic Name: Symptomatic treatment Blocks Drowsiness, Extrapyramidal Hypersensitivity to Assessment: Avoid tasks that
Metoclopramide of diabetic dopamine/serotonin restlessness, reactions (Motor metoclopramide. Assess for require alertness,
gastroparesis, receptors in fatigue, lethargy, restlessness, Concurrent use of dehydration motor skills until
Trade Name: prevent/treat chemoreceptor trigger dizziness, anxiety, medications likely (poor skin turgor, response to drug
Parkinsonism,
Reglan nausea/vomiting after zone of the CNS. headache, insomnia, to produce dry mucous is established.
surgery Enhances breast tardive dyskinesia). membranes, Report involuntary
extrapyramidal
acetylcholine response tenderness, altered Neuroleptic reactions. longitudinal eye, facial, limb
Dose: 10 mg
in upper menstruation, malignant Situations in which furrows in movement
GI tract, causing constipation, rash, dry syndrome GI motility may be tongue). (extrapyramidal
increased motility and mouth, galactorrhea, (diaphoresis, fever, dangerous (e.g., GI Assess for reaction).
Form: accelerated gastric gynecomastia. hemorrhage, GI nausea, Avoid alcohol.
unstable
Tablets; Injection emptying without perforation/ vomiting,
solution B/P, muscular
stimulating gastric, obstruction. abdominal
biliary, or pancreatic rigidity) has been
History of seizure distention, bowel
Route: secretions; increases reported. sounds.
disorder
PO, IV lower esophageal Pheochromocytom Implementation:
sphincter a Be aware that
Drug Classification: tone. metoclopramide
Antiemetic therapy should
Therapeutic Effect: not be used in
Safe Dose Range: Accelerates patients with
PO: 10 mg q6h intestinal transit, depression
IV: 5-10 mg promotes gastric because of
emptying. Relieves increased risk of
nausea, vomiting. suicidal ideation.
Use
metoclopramide
cautiously in
patients with
hypertension
because it may
increase
catecholamine
levels. Monitor
blood pressure
throughout
therapy.
For I.V. use, do
Republic of the Philippines
PALAWAN STATE UNIVERSITY
Puerto Princesa City
DRUG STUDY
not dilute doses
of 10 mg or less.
Give drug over 1
to 2 minutes. For
doses larger than
10 mg, dilute in
50 ml normal
saline solution,
half-normal
(0.45) saline
solution, D5W, or
lactated Ringer’s
solution and
infuse over at
least 15 minutes.
Avoid rapid I.V.
delivery because
it may cause
anxiety,
restlessness, and
drowsiness.
Monitoring:
Monitor for
anxiety,
restlessness,
extrapyramidal
symptoms (EPS)
during IV
administration
Monitor patient,
especially one
with heart failure
or cirrhosis, for
possible fluid
retention or
volume overload
due to transient
increase in
Republic of the Philippines
PALAWAN STATE UNIVERSITY
Puerto Princesa City
DRUG STUDY
plasma
aldosterone
level.
Monitor patient
for abnormal
behaviors or
thoughts
suggestive of
suicidal ideation
because
depression may
occur while
taking
metoclopramide
even in patients
without a history
of depression.
Evaluation:
Evaluate for
therapeutic response
from gastroparesis
(nausea, vomiting,
bloating).