Zofran (Ondansetron)
Zofran (Ondansetron)
Zofran (Ondansetron)
Why is your patient getting this medication For IV meds, compatibility with IV drips and/or
Nausea solutions
Administer undiluted immediately before induction of
anesthesia or postoperatively if nausea and vomiting occur
shortly after surgery, Dilute doses for prevention of nausea
and vomiting associated with chemotherapy in 50 ml of
D5W, 0.9% NaCl, D5/0.9% NaCl, D5/0.45% NaCl.
Solution is clear and colorless. Stable for 7 days at room
temperature following dilution.
Mechanism of action and indications Nursing Implications (what to focus on)
(Why med ordered) Contraindications/warnings/interactions
Blocks the effects of serotonin at 5-HT3-receptor Hypersensitivity,
sites (selective antagonist) located in vagal nerve
terminals and the chemoreceptor trigger zone in the L
CNS. i
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Interactions with other patient drugs, OTC or Lab value alterations caused by medicine
herbal medicines (ask patient specifically) May cause transient ↑ in serum bilirubin, AST, and ALT
None known for this patient levels.
Be sure to teach the patient the following about this
medication
Instruct patient to take ondansetron as directed, Advise
patient to notify health care professional immediately if
involuntary movement of eyes, face, or limbs occurs.