Valvular Heart Diseases
Valvular Heart Diseases
Valvular Heart Diseases
DISEASES
REGURGITATION
Backward flow of blood through a heart
valve
STENOSIS
Narrowing or obstruction of a valve’s
orifice
PROLAPSE
Stretching of an AV valve leaflet into the
atrium during systole
A. Mitral Valve Prolapse
cause: inherited connective tissue
disorder causing an enlargement of
the mitral valve leaflet/s
usually asymptomatic
mitral click (extra heart
sound)/murmur: often the first & only
sign of MVP
B. Mitral Regurgitation
Causes: degenerative changes,
ischemia of the left ventricle, rheumatic
heart disease, myxomatous changes,
infective endocarditis, collagen-vascular
diseases, cardiomyopathy, ischemic
heart disease
Left atrium eventually hypertrophies and
dilates, lungs become congested
Systolic murmur (high-pitched, blowing
sound)
C. Mitral Stenosis
Cause: rheumatic endocarditis
Also leads to left atrial hypertrophy,
pulmonary congestion and right ventricular
failure
Symptoms develop with 1/3 to ½ reduction
of valve opening (1st: dyspnea on exertion)
Poor ventricular filling ⇢ ⇩ CO
Low-pitched, rumbling diastolic murmur,
atrial dysrhythmias
D. Aortic Regurgitation
Inflammatory lesions that deform the leaflets
of the aortic valve; infective or rheumatic
endocarditis, congenital abnormalities,
aneurysm, blunt chest trauma, deterioration
of an aortic valve replacement
Leads to left ventricular failure
High-pitched, diastolic murmur at 3rd or 4th
ICS at the left sternal border
Widened pulse pressure
Water-hammer (Corrigan’s) pulse
E. Aortic Stenosis
Causes: Degenerative calcification,
congenital leaflet malformations,
rheumatic endocarditis
Asymptomatic
Leads to left ventricular failure
BP and pulse pressure may be low
systolic crescendo-decrescendo
murmur over the aortic area, S4 heart
sound; vibration felt over base of heart
MANIFESTATIONS COMPLICATIONS