HOQOL: Measuring Quality of Life

Introducing the WHOQOL instruments

The Constitution of the World Health Organization (WHO) defines health as "A state of complete physical,
mental, and social well-being not merely the absence of disease . . .". It follows that the measurement of
health and the effects of health care must include not only an indication of changes in the frequency and
severity of diseases but also an estimation of well being and this can be assessed by measuring the
improvement in the quality of life related to health care. Although there are generally satisfactory ways of
measuring the frequency and severity of diseases this is not the case in so far as the measurement of well
being and quality of life are concerned. WHO, with the aid of 15 collaborating centres around the world, has
therefore developed two instruments for measuring quality of life (the WHOQOL-100 and the WHOQOL-
BREF), that can be used in a variety of cultural settings whilst allowing the results from different
populations and countries to be compared. These instruments have many uses, including use in medical
practice, research, audit, and in policy making.
WHO defines Quality of Life as an individual's perception of their position in life in the context of the
culture and value systems in which they live and in relation to their goals, expectations, standards and
concerns. It is a broad ranging concept affected in a complex way by the person's physical health,
psychological state, personal beliefs, social relationships and their relationship to salient features of their
environment.
Strengths of the WHOQOL instruments
The WHOQOL instruments were developed cross-culturally
The WHOQOL-100 was developed simultaneously in 15 field centres around the world. The important
aspects of quality of life and ways of asking about quality of life were drafted on the basis of statements
made by patients with a range of diseases, by well people and by health professionals in a variety of cultures.
The instrument was rigorously tested to assess its validity and reliability in each of the field centres and is
currently being tested to assess responsiveness to change. The WHOQOL-BREF, an abbreviated 26 item
version of the WHOQOL-100, was developed using data from the field-trial version of the WHOQOL-100.
The WHOQOL instruments can be used in particular cultural settings, but at the same time results are
comparable across cultures. The WHOQOL is now available in over 20 different languages and its
development in further languages is progressing.
The WHOQOL instruments place primary importance on the perception of the
individual
Most assessments in medicine are obtained by examinations by health workers and laboratory tests. The
WHOQOL instruments, by focusing on individuals' own views of their well being, provide a new
perspective on disease. For example, that diabetes involves poor body regulation of blood glucose is well
understood, but the effect of the illness on the perception that individuals have of their social relationships,
working capacity, and financial status has received little systematic attention. The WHOQOL instruments
are tools that will enable this type of research to be carried out. They not only inquire about the functioning
of people with diabetes, across a range of areas but also how satisfied the patients are with their functioning
and with effects of treatment.
Systematic development of the WHOQOL-100
The method used to develop the WHOQOL-100 involved considerable research and checking over several
years to ensure that it accurately measures the issues that are important to a person's quality of life, and that
it does so reliably. The institutions which participated in this research now serve as reference centres and can
provide technical support to users in their cultural setting (see later section for contact information). In return
for this support, centres request a copy of data collected to be sent to them.
The Instruments have different forms for different uses
The core WHOQOL instruments can assess quality of life in a variety of situations and population groups. In
addition, modules are being developed to allow more detailed assessments of specific populations (e.g.
cancer patients, refugees, the elderly and those with certain diseases, such as HIV/AIDS.
Administration of the WHOQOL instruments
The national versions of the WHOQOL
The WHOQOL instruments are available in over 20 different languages. The appropriate language version,
and permission for using it, can be obtained from the appropriate national centre, as listed on pages 7-8.
Centres may request a copy of data collected for collation in a national data set. A methodology has been
developed for new centres wishing to develop further language versions of the WHOQOL-100 or the
WHOQOL-BREF. This information can be obtained from The WHOQOL Group, Programme on Mental
Health, World Health Organisation, CH-1211, Geneva 27, Switzerland. The WHOQOL-BREF is self-
administered if respondents have sufficient ability: otherwise, interviewer-assisted or interview-administered
forms should be used.
Scoring the WHOQOL instruments
The WHOQOL-100 produces scores relating to particular facets of quality of life (e.g. positive feelings,
social support, financial resources), scores relating to larger domains(e.g. physical, psychological, social
relationships) and a score relating to overall quality of life and general health. The WHOQOL-BREF
produces domain scores, but not individual facet scores. Details on scoring are included in manuals available
from The WHOQOL Group, Programme on Mental Health, World Health Organisation, CH-1211 Geneva
27, Switzerland. Syntax files for checking and cleaning data, and for computing facet and domain scores are
also available from The WHOQOL Group.
Psychometric properties of the WHOQOL instruments
Both the WHOQOL-100 and the WHOQOL-BREF have been shown to display good discriminant validity,
content validity and test-retest reliability. Their sensitivity to change is currently being assessed. Domain
scores produced by the WHOQOL-BREF have been shown to correlate at around 0.9 with The WHOQOL-
100 domain scores.
The uses of the WHOQOL instruments
In medical practice
In clinical practice the WHOQOL instruments may be used with other forms of assessment, giving valuable
information that can indicate areas in which a person is most affected and help the practitioner in making the
best choices in patient care. In addition they may be used to measure change in quality of life over the course
of treatment.
Improving the doctor-patient relationship
By increasing the physician's understanding of how disease affects a patient's quality of life, the interaction
between patient and doctor will change and improve. This gives more meaning and fulfilment to the work of
the doctor and leads to the patient being provided with more comprehensive health care. Because a more
complete form of assessment covering different aspects of patients' functioning is being carried out, patients
themselves may find their health care more meaningful.
In assessing the effectiveness and relative merits of different treatments
The WHOQOL instruments can form a part of the evaluation of treatments. For example, chemotherapy for
cancer may prolong a person's life, but may only do so at considerable cost to their quality of life. By using
the WHOQOL instruments to look at changes in the person's well being over the course of treatment, a
much fuller picture can be gained.
In health services evaluation
In the periodic review of the completeness and quality of medical services, the patients' concerns are of
importance. The instruments provide an invaluable supplementary appraisal of health care services, by
 yielding a measure of the relationship between the health care service and patients' quality of life, and also
by directly presenting a measure of patients' perception of the quality and availability of health care.
In research
The WHOQOL instruments provide new insights into the nature of disease by assessing how disease impairs
or impacts the subjective well being of a person across a whole range of areas.
In policy making
When health providers implement new policies it is important that the effect of policy changes on the quality
of life of people in contact with health services is evaluated. The WHOQOL instruments allow such
monitoring of policy changes.
The Structure of the WHOQOL-100
The structure of the WHOQOL-100 reflects the issues that a group of scientific experts as well as lay people
in each of the field centres felt were important to quality of life. The six broad domains of quality of life, and
the twenty-four facets covered are shown below. Four items are included for each facet, as well as four
general items covering subjective overall QOL and health, producing a total of 100 items in the assessment.
All items are rated on a five point scale (1-5).
Domains and facets incorporated within domains
Overall Quality of Life and General Health
Physical Health
 Energy and fatigue
 Pain and discomfort
 Sleep and rest
Psychological
 Bodily image and appearance
 Negative feelings
 Positive feelings
 Self-esteem
 Thinking, learning, memory and concentration
Level of Independence
 Mobility
 Activities of daily living
 Dependence on medicinal substances and medical aids
 Work capacity
Social Relations
 Personal relationships
 Social support
 Sexual activity
Environment
 Financial resources
 Freedom, physical safety and security
 Health and social care: accessibility and quality
 Home environment
 Opportunities for acquiring new information and skills
 Participation in and opportunities for recreation/leisure
 Physical environment (pollution/noise/traffic/climate)
 Transport
Spirituality/Religion/Personal beliefs
 Religion/Spirituality/Personal beliefs (Single facet)
 Structure of the WHOQOL-BREF
 The WHOQOL-BREF contains two items from the Overall Quality of Life and General Health, and
one item from each of the 24 facets included in The WHOQOL-100. Recent analysis of The
WHOQOL-100 structure has suggested the possibility of merging domains 1 and 3, and also
 merging domains 2 and 6, thereby creating four domains of quality of life. In our current approach
to scoring the WHOQOL-BREF, these domains have been merged therefore and four major
domains are assessed: physical, psychological, social relationships and environment. The
WHOQOL-BREF is currently being field tested.

Future Developments
A number of WHOQOL centres have begun to develop additional modules to The WHOQOL which will
provide greater detail on particular aspects of the quality of life of those, for instance, with certain diseases.
Some studies have led to the development of national items to supplement the core WHOQOL. These reflect
special aspects of quality of life not included in the core because they are not universally valued. A scoring
system is being developed which will permit these national items or modules to be included in national data
analyses.
Principal Investigators and Field Sites Involved in the Development of the WHOQOL
Instruments
The WHOQOL instruments are provided to serious researchers and must be used in the local national
language. In order to obtain permission for use of the language versions listed below it is necessary to
contact the collaborating sites directly.
Spanish (Argentina)
Dr Sylvia Bonicatto, FUNDONAR, Fundacion Oncologica Argentina, Calle 37 Numero 423, La Plata 1900,
Argentina, Tel/Fax: ..54 21 25 3406, e-mail: [email protected]
Chinese (Australian)
Dr Gao Yongping, Hebei Mental Health Center, 10 Weisheng Road, Baoding City, Hebei Province 071000,
People's Republic of China, Tel: 2022688
English (Australian)
Professor Helen Herrman, Department of Psychiatry, St. Vincent's Mental Health Service and University of
Melbourne Department of Psychiatry, 41 Victoria Parade, Fitzroy, Vic. 3065, Australia, Tel:..61 3 9288
4751, Fax:..61 3 9288 4802, e-mail: [email protected]
Portuguese (Brazil)
Dr Marcelo Fleck, University of the State of Rio Grande do Sul, Department of Psychiatry and Legal
Medicine, Rua Ramiro Barcelos, 2350 Sala 177C - HCPA, CEP 90035-003 Bairro Rio Branco, Porto
Alegre, Brazil, Tel/Fax: ..55 51 330 5655, Fax: ..55 51 330 8965, e-mail: [email protected]
Bulgarian
Dr Nikolai Butorin, National Centre for Interdisciplinary Human Studies, 15 Dim. Nestorov Str., 1431 Sofia,
Bulgaria, Tel: ..359 2 59 80 39, Fax: ..359 2 59 11 19, e-mail: [email protected] or
[email protected]
English (Canadian)
Dr Anita E. Molzahn, Faculty of Human and Social Development, University of Victoria, POB 1700,
Victoria BC, Canada, V8W 2Y2, Tel: ..1 250 721 8050, Fax: ..1 250 721 7067, e-mail:
[email protected]
French (Canadian)
Dr Ginette Page, School of Nursing, University of Quebec at Rimouski, 300 avenue des Ursulines,
Rimouski, PQ, Canada, G5L 3A1, Tel: ..1.418 723 1986 ext. 1618, Fax: ..1 418 724 1525, e-mail:
[email protected]
Chinese
Professor Jiqian Fang, Department of Medical Statistics and Community Medicine, School of Public Health,
Sun Yat-Sen University of Medical Sciences, 510089 GuangZhou, People's Republic of China, Fax: ..86 20
8776 5679, e-mail: [email protected]
Croatian
Professor Z. Metelko, Professor S. Szabo, Mrs M. Pibernik-Okanovic, Vuk Vrhovac Institute, University
Clinic for Diabetes, Endocrinology, and Metabolic Diseases, Medical Faculty, University of Zagreb, Dugi
Dol 4A, 10000 Zagreb, Croatia, Tel:..385 1 2 33 22 22, Fax...385 1 2 33 15 15, Private address for
correspondence with Dr S. Szabo: Svacicev trg 13, 10000 Zagreb, Croatia
Czech
Dr Eva Dragomirecka, Psychiatric Demography Unit, Prague Psychiatric Center, Ustavni 91, CZ-181 03
Praha 8-Bohnice, Czech Republic, Tel: ..420 2 855 9483 or 66003 140 to 142, Fax: ..420 2 66003 143 or
855 9805, e-mail: [email protected]
Danish
Professor Per Bech, Psychiatric Research Unit, Frederiksborg General Hospital, DK-3400 Hillerod,
Denmark, Tel: ..45 48 29 32 52, Fax: ..45 42 26 38 77, e-mail: [email protected]
Arabic (Egypt)
Professor Mohammed I Kamel, Community Medicine Department, Faculty of Medicine, Shamplion Street,
21521 Alexandria, Egypt, Tel:..203 484 09 15, Fax:..203 586 33 36, e-mail: [email protected]
Estonian
Professor Mare Teichmann, Tallinn Technical University, Ehitajate tee 5, EE-0026 Tallinn, Estonia,
Tel: ..372 2 53 22 18, Fax: ..372 2 53 24 46, e-mail: [email protected]
French
Dr Nicole Quemada, Centre collaborateur de l'OMS, INSERM Centre Paul Broca, 2ter rue d'Alesia, F -
75014 Paris, France, Tel:..33 1 40 78 92 55, Fax:..33 1 45 80 72 93 Dr Alain Leplege, INSERM U 292,
Hopital de Bicetre, F-94275 Le Kremlin Bicetre Cdx, France, Tel: ..33 1 49 59 19 78 or ..33 1 48 78 04 45,
Fax: ..33 1 45 21 20 75, e-mail: [email protected]
German
Professor M.C. Angermeyer, Dr R. Kilian, Universit�tsklinikum, Klinik und Poliklinik f�r Psychiatrie,
Johannisallee 20, D-04317 Leipzig, Germany, Tel: ..49 171 508 94 49, Fax: ..49 341 97 24 509, e-mail:
[email protected]
Greek
Dr Maria Coccosis, Eginition Hospital, 74 Vas. Sophias Avve., 115 28 Athens, Greece, Tel:..30 1 728 9408
or 7791315 or 6130356, Fax: ..30 1 8048429 or 7242032 or 6800053, e-mail: [email protected]
Chinese (Hong Kong)
Mr Leung Kwok-fai, Hong Kong Project team on Chinese version WHOQOL, Hong Kong Hospital
Authority, c/o Department of Occupational Therapy, Queen Elizabeth Hospital, 30 Gascoigne Road,
Kowloon, Hong Kong, Tel: ..852 2958 6166 or 6077, Fax: ..852 2958 6719, e-mail: [email protected]
Hungarian
Dr Judit Harangozo, Semmelweis University of Medicine, Department of Psychiatry and Psychotherapy,
Balassa u. 6, H-1083 Budapest, Hungary, Tel/Fax: ..36 1 210 0336 or 210 0339, email:
[email protected] and Dr Lajos Kullmann, National Institute for Medical Rehabilitation, P.O. Box
1, H-1528 Budapest 123, Hungary, Tel: ..36 1 200 8830, Fax: ..36 1200 8834
Hindi (India)
Dr Shekhar Saxena, Department of Psychiatry, All India Institute of Medical Sciences, Ansari Nagar, New
Delhi 110029, India, Tel:..91 11 686 4851, Fax:..91 11 686 2663, e-mail: [email protected]
Tamil (India)
Dr Shuba Kumar, Clinical Epidemiology Unit, Physiology Block (Level 1), Chennai Medical College,
Chennai 600 003, India, Tel: ..91 44 561, 550, Fax: ..91 44 580 153, e-mail: gems%[email protected]
Kannada (India)
Dr Prabha S. Chandra, National Institute of Mental Health and Neurosciences, Bangalore 560 029, Inde,
Fax. 91 80 663 18 30, Email: [email protected]
Hebrew (Israel)
Dr Marianne Amir, Department of Behavioral Sciences, The Cukier Goldstein-Goren Building, Ben-Gurion
University of the Negev, P.O.B. 653, 84105 Beer-Sheva, Israel, Tel: ..972 76 472085, Fax: ..972 76 472932,
e-mail: [email protected]
Italian
Dr Giovanni de Girolamo, Istituto Superiore di Sanit�, Laboratorio di epidemiologia e Biostatistica,
Reparto di Epidemiologia Clinica, Viale Regina Elena 299, I-00161 Roma, Italy, Tel: ..39 6 4990 2787, ..39
6 4990 (switchboard), Fax: ..39 6 4938 7173, e-mail: [email protected]
Japanese
Dr Miyako Tazaki, Science University of Tokyo, Kagurzaka 1-3, Shinjuku-ku, Tokyo, Japan, Tel:..81 3
3260 4271, Fax:..81 3 3260 0322, e-mail: [email protected]
Korean
Dr Sung Kil Min, Department of Psychiatry, Yonsei University College of Medicine, GPO Box 8044, Seoul,
Korea, Fax: ...82 2 313 0891
Lithuanian
Professor A. Juozulynas, Kauno str 37 / 59, Center of the Health Law and Economics, 2006 Vilnius,
Lituania
Malay version
Dr Hasanah Che Ismail, Department of Psychiatry, Universiti of Sains Malaysia, Kubang Kerian, Kelantan,
Malaysia, Fax: 09 765 3370, e-mail: [email protected]
Norwegian
Dr Mary Kalfoss, Oslo College, Department of Nursing Education, Bjerregaardsgt. 21, N-0172 Oslo,
Norway, Tel: ..47 22 453 769, Fax. ..47 22 453 799, e-mail: [email protected]
Urdu (Pakistan)
Dr Malik H. Mubbashar, Department of Psychiatry, Rawalpindi General Hospital, Rawalpindi, Pakistan,
Tel: ..92 51 844030 (hospital) ..92 51 453157, Fax: ..92 51 411165 or ..92 5142 9606
Spanish (Panama)
Dr Jaime Arroyo Sucre, Apartado 6651, Panama 5, Panama, Tel:..507 261 5297, Fax:..507 226 4477, e-mail:
[email protected]
Polish
Professor Laura Wolowicka, Karol Marcinowski University of Medical Sciences, Faculty of Nursing and
Health Sciences, A. Wrosek Collegium, 79 Dabrowskiego str. 60, 60-529 Poznan, Poland, Tel: ..48 61 8477
458, Fax: ..48 61 8477 490
Russian
Dr M. Kabanov, Dr G. Burkovsky, Dr A. Lomachenkov, V.M. Bekhterev Psychoneurological Research
Institute, 3 Bekhterev Street, St. Petersburg 193019, Russian Federation, Tel:..7 81 2 567 54 06, Fax:..7 81 2
567 7128 or 27, e-mail: [email protected]
Arabic (Saudi Arabia)
Dr Abdallah Mangoud, Family and Community Medicine, King Fahd University Hospital, P.O. Box 40107,
Al-Khobar 31952, Saudi Arabia, Tel: ..9663 894 3600, Fax: ..9663 864 6945
Slovakian
Dr Damian Kovac, Institute of Experimental Psychology, Slovak Academy of Sciences, Dubravska Cesta 9,
81364 Bratislava, Slovakia, Tel: ..421 7 378 3417, Fax: ..421 7 375584, e-mail: [email protected]
Spanish
Dr Ramona Lucas Carrasco, Armonia 5, 2-3, 08035 Barcelona, Spain, Tel: ..34 93 428 22 97, Fax: ..34 93
428 25 59, e-mail: [email protected] or [email protected]
Swedish
Dr Martin Eisemann, Unit of Medical Psychology, Department of Psychiatry and WHO Collaborating
Centre, Umea University, S-901 85 Umea, Sweden, Tel: ..46 90 785 6320, Fax: ..46 90 135 324 , e-mail:
[email protected]
Thai
Mr Kitikorn Meesapya, Bureau of Mental Health, Technical Development Department of Mental Health,
Ministry of Public Health, Tivanon Rd., Nonthaburi 11000, Thailand, Tel:..66 2 9511300-40 Ext. 8205,
Fax:..66 2 9511384 or 9511386, e-mail: [email protected]
Dutch
Professor G. Van Heck, Mrs J. De Vries, Department of Psychology, Tilburg University, P.O. Box, 90153
NL-5000 LE Tilburg, The Netherlands, Tel:..31 13 466 2522, Fax:..31 13 466 2370, e-mail:
[email protected]
Turkish
Dr Caner Fidaner, Associate Professor of Public Health, Deputy Chief Director of Dr Beh�et Uz Paediatric
Hospital, Director of Izmir Cancer Registry Center, Address for correspondence: Ozlem sokak 7, 35310
G�zelbah�e/Izmir, Turkey, Tel/Fax:..90 232 238 2393 (office), ..90 232 234 3560 (home), e-mail:
[email protected] or [email protected]
English (UK)
Dr S. Skevington, University of Bath, School of Social Sciences, Claverton Down, Bath BA2 7AY, United
Kingdom, Tel:..44 1225 826826, Fax:..44 1225 826381, e-mail: [email protected]
English (USA)
Dr Donald Patrick, Department of Health Services, H689, University of Washington, Box 357660, Seattle,
Washington 98195-7660, USA, Tel:..1 206 616 2981, Fax:..1 206 543 3964, e-mail:
[email protected] Assistant: Cynthia Long, Tel..1 206 616 2979, e-mail:
[email protected]
Zambia
Dr Alan Haworth, Department of Psychiatry, School of Medicine, University of Zambia, POB 30043,
Lusaka, Zambia, Tel: ..260 1 290 395, Fax: ..260 1 252 219 or 223 209 or 222 834, e-mail:
[email protected]
Shona (Zimbabwe)
Dr Jane Mutambirwa, Department of Psychiatry, University of Zimbabwe, P.O. Box A 178, Avondale,
Harare, Zimbabwe, Tel:..263 4 791 631, Fax:..263 4 333 407 or 724 912, e-mail: [email protected]