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    The study aimed to compare the prevalence of potentially inappropriate medication (PIM) use in older patients across different healthcare settings in the Czech Republic. Results showed that the prevalence of PIM use was highest in acute care (86.8%), followed by ambulatory care (74.1%), and lowest in community pharmacy practices (38.4%). Factors associated with higher odds of PIM prescribing included older age, polypharmacy, and depression. The study concluded that PIM prescribing was very common, especially in acute and ambulatory care settings, and interventions are still needed to reduce inappropriate prescribing for older patients, particularly in these settings. Implementing tools to assess and manage PIMs could help lower older patients' exposure to poly

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    The study aimed to compare the prevalence of potentially inappropriate medication (PIM) use in older patients across different healthcare settings in the Czech Republic. Results showed that the prevalence of PIM use was highest in acute care (86.8%), followed by ambulatory care (74.1%), and lowest in community pharmacy practices (38.4%). Factors associated with higher odds of PIM prescribing included older age, polypharmacy, and depression. The study concluded that PIM prescribing was very common, especially in acute and ambulatory care settings, and interventions are still needed to reduce inappropriate prescribing for older patients, particularly in these settings. Implementing tools to assess and manage PIMs could help lower older patients' exposure to poly

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    The study aimed to compare the prevalence of potentially inappropriate medication (PIM) use in older patients across different healthcare settings in the Czech Republic. Results showed that the prevalence of PIM use was highest in acute care (86.8%), followed by ambulatory care (74.1%), and lowest in community pharmacy practices (38.4%). Factors associated with higher odds of PIM prescribing included older age, polypharmacy, and depression. The study concluded that PIM prescribing was very common, especially in acute and ambulatory care settings, and interventions are still needed to reduce inappropriate prescribing for older patients, particularly in these settings. Implementing tools to assess and manage PIMs could help lower older patients' exposure to poly

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    ESCP22SY 1461 Preview 1

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    The study aimed to compare the prevalence of potentially inappropriate medication (PIM) use in older patients across different healthcare settings in the Czech Republic. Results showed that the prevalence of PIM use was highest in acute care (86.8%), followed by ambulatory care (74.1%), and lowest in community pharmacy practices (38.4%). Factors associated with higher odds of PIM prescribing included older age, polypharmacy, and depression. The study concluded that PIM prescribing was very common, especially in acute and ambulatory care settings, and interventions are still needed to reduce inappropriate prescribing for older patients, particularly in these settings. Implementing tools to assess and manage PIMs could help lower older patients' exposure to poly

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    Abstract Submission for ESCP 2022 Symposium

    Public Health

    ESCP22SY-1461
    COMPARATIVE RESULTS ON POTENTIALLY INAPPROPRIATE MEDICATION (PIM) USE IN CZECH OLDER
    PEOPLE IN ACUTE, AMBULATORY CARE AND COMMUNITY PHARMACY PRACTICES: RESULTS FROM THE
    INOMED AND THE EUROAGEISM ESR7 PROJECT
    Jovana Brkic* 1, Ingrid Kummer1, Olena Antonenko1, Areman Bhagya Sri1, Deepak Kumar Bandari 1, Gabriela Vaculova 1,
    Silvia Gresakova1, Akshaya Srikanth Bhagavathula1, Jindra Reissigova2, Daniela Fialova1, 3
    1Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Kralove, Charles University, Hradec

    Kralove, 2Department of Statistical Modelling, Institute of Computer Science, Czech Academy of Sciences, 3Department
    of Geriatrics and Gerontology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic

    Is this work original?: Yes


    Please specify your abstract type: Research abstract
    Background and Objective: Potentially inappropriate medication (PIM) use in older patients has been shown to be highly
    prevalent, but the prevalences widely differ between different settings of care. However, the situation with the prescribing
    of these medications improves with the implementation of clinical pharmacy services in various settings of care. Thus, the
    aim of our study was to compare the prevalence of PIM use in different settings of care in the Czech Republic. This
    abstract presents only preliminary findings.
    Method: We conducted a national study in 3 settings of care − acute care, ambulatory care, and pharmacy practices. In
    each setting of care, 3 bigger facilities from 3 different regions were selected (minimum of 150 patients per facility). All
    older patients aged 65+ were assessed in the period 2018-2020 using the EuroAgeism H2020 ESR7 study protocol
    based on comprehensive geriatric assessment (CGA). This protocol includes more than 350 patient characteristics −
    socio-demographic, clinical assessments, medical history, selected laboratory values and information on medication use.
    As a source of data, medical records, interviews with patients and/or their caregivers and interviews with healthcare
    professionals were used, along with clinical assessments. We used descriptive statistics for determining the prevalence
    of PIM use according to a combination of 3 explicit criteria developed for the European region and applicable to various
    settings of care (Laroche's list, EU(7)-PIM list and PRISCUS list). Stepwise logistic regression was applied to determine
    the factors related to the PIM prescribing. R-software version 4.1.1 was used for data analyses.
    Main outcome measures: The main outcome measure was the prevalence of PIM use.
    Results: Our sample consisted of 1602 patients (589 from acute care, 563 from ambulatory care and 450 from
    community pharmacy practices). The majority of participants were females (56.5%). The prevalence of PIM use was
    68.7% in the total sample, in acute care 86.8%, in ambulatory care 74.1%, and in community pharmacy practices 38.4%.
    The odds of being prescribed PIM were higher in patients aged 75 years and older (OR=1.6; 95%CI(1.2-2.1)), using
    polypharmacy (5+ medications) 8.3 (6.2-11.2), and having depression 1.7 (1.1-2.6), but lower for pharmacy practice
    setting 0.4 (0.3-0.5) and ambulatory care setting 0.6 (0.4-0.8).
    Conclusion: PIM prescribing in the Czech Republic was very high (around 70%), particularly in acute care and
    ambulatory care and predominant in high-risk older patients. Thus, interventions to reduce the very frequent prescribing
    of PIMs to older people are still needed, particularly in these care settings. Implementing PIM assessment and
    management tools might considerably reduce the burden of exposure of older people to the simultaneous risk of
    polypharmacy and PIM use.
    References: The research group was supported by projects: Inomed NO.CZ.02.1.01/0.0/0.0/18_069/0010046,
    EuroAgeism Horizon 2020 MSCF-ITN-764632, Cooperatio research program KSKFI.- Faculty of Pharmacy, Charles
    University, START/MED/093 CZ.02.2.69/0.0/0.0/19_073/0016935, SVV260 551 and I-CARE4OLD H2020 -
    965341 projects.
     

    Disclosure of Interest: None Declared

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