Agents Classified by the IARC Monographs, Volumes 1–131

No CAS. Agente Grupo Volumen Año Información adicional

99-97-8 N,N-Dimethyl-p-toluidine 2B 115 2018
99-80-9 N-Methyl-N,4-dinitrosoaniline 3 1, Sup 7 1987
99-59-2 5-Nitro-ortho-anisidine 3 27, Sup 7 1987
99-57-0 2-Amino-4-nitrophenol 3 57 1993
99-56-9 1,2-Diamino-4-nitrobenzene 3 16, Sup 7 1987
99-55-8 5-Nitro-ortho-toluidine 3 48 1990
99-08-1, Nitrotoluenes 3 65 1996
99-99-0
989-38-8 Rhodamine 6G 3 16, Sup 7 1987
98-95-3 Nitrobenzene 2B 65 1996
98-87-3, alpha-Chlorinated toluenes (benzal chloride, 2A 29, Sup 7, 1999
98-07-7, benzotrichloride, benzyl chloride) and benzoyl 71
100-44-7, chloride (combined exposures)
98-88-4
98-83-9 α-Methylstyrene 2B 101 2013
98-82-8 Cumene 2B 101 2013
98-56-6 4-Chlorobenzotrifluoride 2B 125 2020
online
98-01-1 Furfural 3 63 1995
98-00-0 Furfuryl alcohol 2B 119 2019
97-77-8 Disulfiram 3 12, Sup 7 1987
97-56-3 ortho-Aminoazotoluene 2B 8, Sup 7 1987
97-53-0 Eugenol 3 36, Sup 7 1987
96-48-0 gamma-Butyrolactone 3 11, Sup 7, 1999
71
96-45-7 Ethylenethiourea 3 Sup 7, 79 2001 NB Overall evaluation
downgraded to Group 3
with supporting
evidence from other
relevant data
96-33-3 Methyl acrylate 2B 39, Sup 7, 2019
71, 122
96-24-2 3-Monochloro-1,2-propanediol 2B 101 2013
96-23-1 1,3-Dichloro-2-propanol 2B 101 2013
96-18-4 1,2,3-Trichloropropane 2A 63 1995
96-13-9 2,3-Dibromopropan-1-ol 2B 77 2000
96-12-8 1,2-Dibromo-3-chloropropane 2B 20, Sup 7, 1999
71
96-09-3 Styrene-7,8-oxide 2A Sup 7, 60, 2019 NB Overall evaluation
121 upgraded to Group 2A
with supporting
evidence from other
relevant data
95-85-2 2-Amino-4-chlorophenol 2B 123 2020
online
95-83-0 4-Chloro-ortho-phenylenediamine 2B 27, Sup 7 1987
95-80-7 2,4-Diaminotoluene 2B 16, Sup 7 1987
95-79-4 5-Chloro-ortho-toluidine 3 77 2010
95-78-3 2,5-Xylidine 3 16, Sup 7 1987
 No CAS. Agente Grupo Volumen Año Información adicional
95-70-5 2,5-Diaminotoluene 3 16, Sup 7 1987
95-69-2 4-Chloro-ortho-toluidine 2A 77, 99 2010
95-68-1 2,4-Xylidine 3 16, Sup 7 1987
95-54-5 ortho-Phenylenediamine 2B 123 2020
online
95-53-4 ortho-Toluidine 1 Sup 7, 77, 2012
99, 100F
95-50-1 ortho-Dichlorobenzene 3 Sup 7, 73 1999
95-06-7 Sulfallate 2B 30, Sup 7 1987
94-75-7 2,4-D (2,4-dichlorophenoxyacetic acid) (See 2B 113 2018
also Chlorophenoxy herbicides)
94-59-7 Safrole 2B 10, Sup 7 1987
94-58-6 Dihydrosafrole 2B 10, Sup 7 1987
94-36-0 Benzoyl peroxide 3 36, Sup 7, 1999
71
930-55-2 N-Nitrosopyrrolidine 2B 17, Sup 7 1987
93-15-2 Methyleugenol 2B 101 2013
924-42-5 N-Methylolacrylamide 2B 60, 130 In
prep.
924-16-3 N-Nitrosodi-n-butylamine 2B 17, Sup 7 1987
92-93-3 4-Nitrobiphenyl 3 4, Sup 7 1987
92-87-5 Benzidine 1 29, Sup 7, 2012
99, 100F
92-67-1 4-Aminobiphenyl 1 1, Sup 7, 2012
99, 100F
915-67-3 Amaranth 3 8, Sup 7 1987
91-94-1 3,3'-Dichlorobenzidine 2B 29, Sup 7 1987
91-93-0 3,3'-Dimethoxybenzidine-4,4'-diisocyanate 3 39, Sup 7 1987
91-64-5 Coumarin 3 Sup 7, 77 2000
91-59-8 2-Naphthylamine 1 4, Sup 7, 2012
99, 100F
91-23-6 ortho-Nitroanisole 2A 65, 127 2021 NB Originally evaluated
online as 2-Nitroanisole
91-22-5 Quinoline 2B 121 2019
91-20-3 Naphthalene 2B 82 2002
90370-29-9 4,4',6-Trimethylangelicin plus ultraviolet A 3 Sup 7 1987
radiation
9016-87-9 Polymethylene polyphenyl isocyanate 3 19, Sup 7 1987
9011-14-7 Polymethyl methacrylate 3 19, Sup 7 1987
9011-06-7 Vinylidene chloride-vinyl chloride copolymers 3 19, Sup 7 1987
9010-98-4 Polychloroprene 3 19, Sup 7 1987
9009-54-5 Polyurethane foams 3 19, Sup 7 1987
90045-36-6 Ginkgo biloba extract 2B 108 2016
9004-66-4 Iron-dextran complex 2B 2, Sup 7 1987
9004-51-7 Iron-dextrin complex 3 2, Sup 7 1987
9003-55-8 Styrene-butadiene copolymers 3 19, Sup 7 1987
9003-54-7 Styrene-acrylonitrile copolymers 3 19, Sup .7 1987
9003-53-6 Polystyrene 3 19, Sup 7 1987
9003-39-8 Polyvinyl pyrrolidone 3 19, Sup 7, 1987
71
 No CAS. Agente Grupo Volumen Año Información adicional
9003-22-9 Vinyl chloride-vinyl acetate copolymers 3 19, Sup 7 1987
9003-20-7 Polyvinyl acetate 3 19, Sup 7 1987
9003-07-0 Polypropylene 3 19, Sup 7 1987
9003-01-4 Polyacrylic acid 3 19, Sup 7 1987
9002-89-5 Polyvinyl alcohol 3 19, Sup 7 1987
9002-88-4 Polyethylene 3 19, Sup 7 1987
9002-86-2 Polyvinyl chloride 3 19, Sup 7 1987
9002-84-0 Polytetrafluoroethylene 3 19, Sup 7 1987
9000-38-8 Kava extract 2B 108 2016
9000-07-1 Carrageenan, native 3 31, Sup 7 1987
90-94-8 Michler’s ketone [4,4´-Bis(dimethylamino) 2B 99 2010
benzophenone]
90-65-3 Penicillic acid 3 10, Sup 7 1987
90-43-7 ortho-Phenylphenol 3 73 1999
90-04-0 ortho-Anisidine (see also ortho-Anisidine 2A Sup 7, 73, 2021
hydrochloride) 127 online
89778-26-7 Toremifene 3 66 1996
892-21-7 3-Nitrofluoranthene 3 33, Sup 7 1987
89-82-7 Pulegone 2B 108 2016
89-61-2 1,4-Dichloro-2-nitrobenzene 2B 65, 123 2020
online
88-73-3, Chloronitrobenzenes (see 2-
121-73-3, Chloronitrobenzene, 3-Chloronitrobenzene, 4-
100-00-5 Chloronitrobenzene)
88-73-3 2-Chloronitrobenzene 2B 65, 123 2020
online
88-72-2 2-Nitrotoluene 2A 101 2013 NB Overall evaluation
upgraded to Group 2A
with supporting
evidence from other
relevant data
88-12-0 N-Vinyl-2-pyrrolidone 3 19, Sup 7, 1999
71
88-06-2 2,4,6-Trichlorophenol (see also 2B 117 2019
Polychlorophenols)
88-05-1 2,4,6-Trimethylaniline 3 27, Sup 7 1987
87625-62-5 Ptaquiloside 3 40, Sup 7 1987
87-86-5 Pentachlorophenol (see also 1 53, 71, 2019
Polychlorophenols) 117
87-68-3 Hexachlorobutadiene 3 73 1999
87-62-7 2,6-Dimethylaniline (2,6-Xylidine) 2B 57 1993
87-29-6 Cinnamyl anthranilate 3 Sup 7, 77 2000
868-85-9 Dimethyl hydrogen phosphite 3 48, 71 1999
86-88-4 1-Naphthylthiourea (ANTU) 3 30, Sup 7 1987
86-74-8 Carbazole 2B 32, Sup 7, 2013
71, 103
86-73-7 Fluorene 3 Sup 7, 92 2010
86-57-7 1-Nitronaphthalene 3 46 1989
86-54-4 Hydralazine 3 24, Sup 7 1987
86-30-6 N-Nitrosodiphenylamine 3 27, Sup 7 1987
 No CAS. Agente Grupo Volumen Año Información adicional
85878-63-3 7-Methylpyrido[3,4-c]psoralen 3 40, Sup 7 1987
85878-62-2 Pyrido[3,4-c]psoralen 3 40, Sup 7 1987
85502-23-4 3-(N-Nitrosomethylamino)propionaldehyde 3 Sup 7, 85 2004
85-86-9 Sudan III 3 8, Sup 7 1987
85-84-7 Yellow AB 3 8, Sup 7 1987
85-83-6 Scarlet Red 3 8, Sup 7 1987
85-68-7 Butyl benzyl phthalate 3 Sup 7, 73 1999
85-01-8 Phenanthrene 3 Sup 7, 92 2010
846-50-4 Temazepam 3 66 1996
842-07-9 Sudan I 3 8, Sup 7 1987
84-65-1 Anthraquinone 2B 101 2013
838-88-0 4,4'-Methylene bis(2-methylaniline) 2B 4, Sup 7 1987
83463-62-1 Bromochloroacetonitrile 3 52, 71 1999
832-69-9 1-Methylphenanthrene 3 Sup 7, 92 2010
83-67-0 Theobromine 3 51 1991
83-66-9 Musk ambrette 3 65 1996
83-63-6 Diacetylaminoazotoluene 3 8, Sup 7 1987
83-32-9 Acenaphthene 3 92 2010
828-00-2 Dimethoxane 3 15, Sup 7 1987
82413-20-5 Droloxifene 3 66 1996
822-36-6 4-Methylimidazole 2B 101 2013
82-68-8 Quintozene (Pentachloronitrobenzene) 3 5, Sup 7 1987
82-28-0 1-Amino-2-methylanthraquinone 3 27, Sup 7 1987
817-09-4 Trichlormethine (Trimustine hydrochloride) 2B Sup 7, 50 1990
81-88-9 Rhodamine B 3 16, Sup 7 1987
81-49-2 1-Amino-2,4-dibromoanthraquinone 2B 101 2013
81-15-2 Musk xylene 3 65 1996
81-07-2 Saccharin and its salts 3 Sup 7, 73 1999 NB Overall evaluation
downgraded to Group 3
with supporting
evidence from other
relevant data
8052-42-4, Bitumens, occupational exposure to straight- 2B 103 2013
64741-56-6 run bitumens and their emissions during road
paving
8052-42-4 Bitumens, extracts of steam-refined and air- 35, Sup 7 1987
refined; steam-refined, cracking-residue and
air-refined bitumens (see Bitumens,
occupational exposures)
8047-67-4 Saccharated iron oxide 3 2, Sup 7 1987
804-36-4 Nitrovin 3 31, Sup 7 1987
8018-07-3 Acriflavinium chloride 3 13, Sup 7 1987
8007-45-2 Coal tars (see Coal-tar distillation) 35, Sup 7 1987
8007-45-2 Coal-tar distillation 1 92, 100F 2012
8002-05-9 Crude oil 3 45 1989
8001-58-9 Creosotes 2A Sup 7, 92 2010
8001-50-1 Terpene polychlorinates (Strobane®) 3 5, Sup 7 1987
8001-35-2 Toxaphene (Polychlorinated camphenes) 2B Sup 7, 79 2001
800-24-8 Aziridyl benzoquinone 3 9, Sup 7 1987
 No CAS. Agente Grupo Volumen Año Información adicional
80-62-6 Methyl methacrylate 3 Sup 7, 60 1994
80-08-0 Dapsone 3 24, Sup 7 1987
794-93-4 Dihydroxymethylfuratrizine (see also 3 24, Sup 7 1987
Panfuran S)
794-93-4 Panfuran S (containing 2B 24, Sup 7 1987
dihydroxymethylfuratrizine)
79-94-7 Tetrabromobisphenol A 2A 115 2018 NB Overall evaluation
upgraded to Group 2A
with supporting
evidence from
mechanistic data
79-46-9 2-Nitropropane 2B 29, Sup 7, 1999
71
79-44-7 Dimethylcarbamoyl chloride 2A 12, Sup 7, 1999 NB Overall evaluation
71 upgraded to Group 2A
with supporting
evidence from other
relevant data
79-43-6 Dichloroacetic acid 2B 63, 84, 2014
106
79-34-5 1,1,2,2-Tetrachloroethane 2B 20, Sup 7, 2014
71, 106
79-10-7 Acrylic acid 3 19, Sup 7, 1999
71
79-06-1 Acrylamide 2A 60, Sup 7 1994 NB Overall evaluation
upgraded to Group 2A
with supporting
evidence from other
relevant data
79-01-6 Trichloroethylene 1 Sup 7, 63, 2014
106
79-00-5 1,1,2-Trichloroethane 3 52, 71 1999
789-07-1 2-Nitropyrene 3 46 1989
78-98-8 Methylglyoxal 3 51 1991
78-87-5 1,2-Dichloropropane 1 41, Sup 7, 2017
71, 110
78-79-5 Isoprene 2B 60, 71 1999
78-59-1 Isophorone 2B 130 In
prep.
7782-49-2 Selenium and selenium compounds 3 9, Sup 7 1987
7758-19-2 Sodium chlorite 3 52 1991
7758-01-2 Potassium bromate 2B Sup 7, 73 1999
77500-04-0 MeIQx (2-Amino-3,8-dimethylimidazo[4,5- 2B Sup 7, 56 1993
f]quinoxaline)
77439-76-0 3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)- 2B 84 2004
furanone
7722-84-1 Hydrogen peroxide 3 36, Sup 7, 1999
71
77094-11-2 MeIQ (2-Amino-3,4-dimethylimidazo[4,5- 2B Sup 7, 56 1993
f]quinoline)
77-78-1 Dimethyl sulfate 2A 4, Sup 7, 1999 NB Overall evaluation
71 upgraded to Group 2A
with supporting
evidence from other
 No CAS. Agente Grupo Volumen Año Información adicional
relevant data
77-09-8 Phenolphthalein 2B 76 2000
7664-93-9 Strong-inorganic-acid mists containing
sulfuric acid (see Acid mists)
765-34-4 Glycidaldehyde 2B 11, Sup 7, 1999
71
7647-01-0 Hydrochloric acid 3 54 1992
7631-86-9 Silica, amorphous 3 Sup 7, 68 1997
76180-96-6 IQ (2-Amino-3-methylimidazo[4,5-f]quinoline) 2A Sup 7, 56 1993 NB Overall evaluation
upgraded to Group 2A
with supporting
evidence from other
relevant data
76-44-8 Heptachlor 2B Sup 7, 53, 2001
79
76-03-9 Trichloroacetic acid 2B 63, 84, 2014
106
76-01-7 Pentachloroethane 3 41, Sup 7, 1999
71
759-73-9 N-Ethyl-N-nitrosourea 2A 17, Sup 7 1987 NB Overall evaluation
upgraded to Group 2A
with supporting
evidence from other
relevant data
7572-29-4 Dichloroacetylene 3 39, Sup 7, 1999
71
75321-20-9 1,3-Dinitropyrene 2B 46, 105 2014
7519-36-0 N-Nitrosoproline 3 17, Sup 7 1987
75-88-7 2-Chloro-1,1,1-trifluoroethane 3 41, Sup 7, 1999
71
75-87-6 Chloral 2A 63, 84, 2014
106
75-60-5 Dimethylarsinic acid 2B 100C 2012
75-56-9 Propylene oxide 2B Sup 7, 60 1994
75-55-8 2-Methylaziridine (Propyleneimine) 2B 9, Sup 7, 1999
71
75-52-5 Nitromethane 2B 77 2000
75-45-6 Chlorodifluoromethane 3 41, Sup 7, 1999
71
75-38-7 Vinylidene fluoride 3 39, Sup 7, 1999
71
75-35-4 Vinylidene chloride 2B 39, Sup 7, 2019
71, 119
75-27-4 Bromodichloromethane 2B 52, 71 1999
75-25-2 Bromoform 3 52, 71 1999
75-21-8 Ethylene oxide 1 Sup 7, 60, 2012 NB Overall evaluation
97, 100F upgraded to Group 1
based on mechanistic
and other relevant data
75-09-2 Dichloromethane (Methylene chloride) 2A Sup 7, 71, 2017
110
75-07-0 Acetaldehyde 2B 36, Sup 7, 1999
71
 No CAS. Agente Grupo Volumen Año Información adicional
75-07-0 Acetaldehyde associated with consumption 1 100E 2012
of alcoholic beverages
75-02-5 Vinyl fluoride 2A Sup 7, 63, 2008 NB (1) Overall
97 evaluation upgraded to
Group 2A based on
mechanistic and other
relevant data; (2) For
practical purposes, vinyl
fluoride should be
considered to act
similarly to the human
carcinogen vinyl
chloride
75-01-4 Vinyl chloride 1 Sup 7, 97, 2012
100F
75-00-3 Chloroethane 3 52, 71 1999
7496-02-8 6-Nitrochrysene 2A Sup 7, 46, 2014 NB Overall evaluation
105 upgraded to Group 2A
with supporting
evidence from other
relevant data
7481-89-2 Zalcitabine 2B 76 2000
7460-84-6 Glycidyl stearate 3 11, Sup 7 1987
7446-09-5 Sulfur dioxide 3 54 1992
7440-48-4, Cobalt metal with tungsten carbide 2A 86 2006
12070-12-1
7440-48-4 Cobalt metal (without tungsten carbide or 2A 52, 86, In
other metal alloys) 131 prep.
7440-47-3 Chromium, metallic 3 Sup 7, 49 1990
7440-43-9 Cadmium and cadmium compounds 1 58, 100C 2012
7440-41-7 Beryllium and beryllium compounds 1 Sup 7, 58, 2012
100C
7440-38-2 Arsenic and inorganic arsenic compounds 1 23, Sup 7, 2012
100C
7440-29-1 Thorium-232 and its decay products 1 78, 100D 2012
7440-07-5 Plutonium 1 78, 100D 2012
7440-02-0 Nickel, metallic 2B Sup 7, 49 1990
7439-97-6 Mercury and inorganic mercury compounds 3 58 1993
7439-92-1 Lead 2B 23, Sup 7 1987
74-96-4 Bromoethane 3 52, 71 1999
74-88-4 Methyl iodide 3 41, Sup 7, 1999
71
74-87-3 Methyl chloride 3 41, Sup 7, 1999
71
74-85-1 Ethylene 3 Sup 7, 60 1994
74-83-9 Methyl bromide 3 41, Sup 7, 1999
71
73459-03-7 5-Methylangelicin plus ultraviolet A radiation 3 Sup 7 1987
723-46-6 Sulfamethoxazole 3 Sup 7, 79 2001
7220-79-3 Methylene blue 3 108 2016
72-57-1 Trypan blue 2B 8, Sup 7 1987
72-43-5 Methoxychlor 3 20, Sup 7 1987
72-20-8 Endrin 3 5, Sup 7 1987
 No CAS. Agente Grupo Volumen Año Información adicional
71267-22-6 N'-Nitrosoanatabine (NAT) 3 37, Sup 7, 2007
89
712-68-5 2-Amino-5-(5-nitro-2-furyl)-1,3,4-thiadiazole 2B 7, Sup 7 1987
71-58-9 Medroxyprogesterone acetate 2B 21, Sup 7 1987
71-55-6 1,1,1-Trichloroethane 2A 20, Sup 7, In
71, 130 prep.
71-43-2 Benzene 1 29, Sup 7. 2018
100F, 120
7099-43-6 5,6-Cyclopenteno-1,2-benzanthracene 3 92 2010
70-30-4 Hexachlorophene 3 20, Sup 7 1987
70-25-7 N-Methyl-N´-nitro-N-nitrosoguanidine (MNNG) 2A 4, Sup 7 1987 NB Overall evaluation
upgraded to Group 2A
with supporting
evidence from other
relevant data
69655-05-6 Didanosine 3 76 2000
693-98-1 2-Methylimidazole 2B 101 2013
69-53-4 Ampicillin 3 50 1990
6870-67-3 Jacobine 3 10, Sup 7 1987
68603-42-9 Coconut oil diethanolamine condensate 2B 101 2013
684-93-5 N-Methyl-N-nitrosourea 2A 17, Sup 7 1987 NB Overall evaluation
upgraded to Group 2A
with supporting
evidence from other
relevant data
68308-34-9 Shale oils 1 35, Sup 7, 2012
100F
68006-83-7 MeA-alpha-C (2-Amino-3-methyl-9H- 2B 40, Sup 7 1987
pyrido[2,3-b]indole)
680-31-9 Hexamethylphosphoramide 2B 15, Sup 7, 1999
71
68-76-8 Tris(aziridinyl)-para-benzoquinone 3 9, Sup 7 1987
(Triaziquone)
68-12-2 N,N-Dimethylformamide 2A 47, 71, 2018
115
67730-11-4 Glu-P-1 (2-Amino-6-methyldipyrido[1,2-a:3',2'- 2B 40, Sup 7 1987
d]imidazole)
67730-10-3 Glu-P-2 (2-Aminodipyrido[1,2-a:3',2'- 2B 40, Sup 7 1987
d]imidazole)
67-72-1 Hexachloroethane 2B 73 1999
67-66-3 Chloroform 2B Sup 7, 73 1999
67-63-0 Isopropyl alcohol 3 15, Sup 7, 1999
71
67-45-8 Furazolidone 3 31, Sup 7 1987
67-20-9 Nitrofurantoin 3 50 1990
66733-21-9 Erionite 1 42, Sup 7, 2012
100C
66-75-1 Uracil mustard 2B 9, Sup 7 1987
66-27-3 Methyl methanesulfonate 2A 7, Sup 7, 1999 NB Overall evaluation
71 upgraded to Group 2A
with supporting
evidence from other
relevant data
 No CAS. Agente Grupo Volumen Año Información adicional
65996-93-2 Coal-tar pitch 1 35, Sup 7, 2012
100F
65271-80-9 Mitoxantrone 2B 76 2000
64742-93-4 Bitumens, occupational exposure to oxidized 2A 103 2013
bitumens and their emissions during roofing
6459-94-5 CI Acid Red 114 2B 57 1993
64436-13-1 Arsenobetaine and other organic arsenic 3 100C 2012
compounds that are not metabolized in
humans
6416-57-5 Sudan Brown RR 3 8, Sup 7 1987
641-48-5 1,2-Dihydroaceanthrylene 3 92 2010
64-67-5 Diethyl sulfate 2A 54, 71 1999 NB Overall evaluation
upgraded to Group 2A
with supporting
evidence from other
relevant data
64-17-5 Ethanol in alcoholic beverages 1 96, 100E 2012
6373-74-6 CI Acid Orange 3 3 57 1993
637-07-0 Clofibrate 3 Sup 7, 66 1996
6368-72-5 Sudan Red 7B 3 8, Sup 7 1987
6358-53-8 Citrus Red No. 2 2B 8, Sup 7 1987
632-99-5 Magenta 2B Sup 7, 57, 2012
99, 100F
631-64-1 Dibromoacetic acid 2B 101 2013
63041-90-7 6-Nitrobenzo[a]pyrene 3 Sup 7, 46 1989
630-20-6 1,1,1,2-Tetrachloroethane 2B 41, Sup 7, 2014
71, 106
63-92-3 Phenoxybenzamine hydrochloride 2B 24, Sup 7 1987
63-25-2 Carbaryl 3 12, Sup 7 1987
627-12-3 n-Propyl carbamate 3 12, Sup 7 1987
62450-07-1 Trp-P-2 (3-Amino-1-methyl-5H-pyrido[4,3- 2B 31, Sup 7 1987
b]indole)
62450-06-0 Trp-P-1 (3-Amino-1,4-dimethyl-5H-pyrido[4,3- 2B 31, Sup 7 1987
b]indole)
621-64-7 N-Nitrosodi-n-propylamine 2B 17, Sup 7 1987
62-75-9 N-Nitrosodimethylamine 2A 17, Sup 7 1987 NB Overall evaluation
upgraded to Group 2A
with supporting
evidence from other
relevant data
62-73-7 Dichlorvos 2B Sup 7, 53 1991
62-56-6 Thiourea 3 Sup 7, 79 2001
62-55-5 Thioacetamide 2B 7, Sup 7 1987
62-53-3 Aniline (see also Aniline hydrochloride) 2A 27, Sup 7, 2021
127 online
62-50-0 Ethyl methanesulfonate 2B 7, Sup 7 1987
62-44-2 Phenacetin 1 24, Sup 7, 2012 NB Overall evaluation
100A upgraded to Group 1
with supporting
evidence from other
relevant data
618-85-9 3,5-Dinitrotoluene 3 65 1996
 No CAS. Agente Grupo Volumen Año Información adicional
6164-98-3 Chlordimeform 3 30, Sup 7 1987
615-53-2 N-Methyl-N-nitrosourethane 2B 4, Sup 7 1987
615-28-1 ortho-Phenylenediamine dihydrochloride 2B 123 2020
online
615-05-4 2,4-Diaminoanisole 2B Sup 7, 79 2001
613-35-4 N,N'-Diacetylbenzidine 2B 16, Sup 7 1987
611-06-3 2,4-Dichloro-1-nitrobenzene 2B 123 2020
online
61-82-5 Amitrole 3 79, Sup 7 2001 NB Overall evaluation
downgraded to Group 3
with supporting
evidence from other
relevant data
61-57-4 Niridazole 2B 13, Sup 7 1987
609-20-1 2,6-Dichloro-para-phenylenediamine 3 39, Sup 7 1987
607-57-8 2-Nitrofluorene 2B 46, 105 2014
606-20-2 2,6-Dinitrotoluene 2B 65 1996
604-75-1 Oxazepam 2B Sup 7, 66 1996
603-48-5 Leucogentian violet (see also Gentian violet) 3 129 2022
online
602-87-9 5-Nitroacenaphthene 2B 16, Sup 7 1987
602-60-8 9-Nitroanthracene 3 33, Sup 7 1987
60153-49-3 3-(N-Nitrosomethylamino)propionitrile 2B Sup 7, 85 2004
60102-37-6 Petasitenine 3 31, Sup 7 1987
60-57-1, Dieldrin, and aldrin metabolized to dieldrin 2A 5, Sup 7, 2019
309-00-2 117
60-57-1 Dieldrin (see Dieldrin, and aldrin metabolized
to dieldrin)
60-56-0 Methimazole 3 79 2001
60-35-5 Acetamide 2B 7, Sup 7, 1999
71
60-11-7 para-Dimethylaminoazobenzene 2B 8, Sup 7 1987
60-09-3 para-Aminoazobenzene 2B 8, Sup 7 1987
599-79-1 Sulfasalazine 2B 108 2016
5989-27-5 d-Limonene 3 56, 73 1999 NB Overall evaluation
downgraded to Group 3
with supporting
evidence from other
relevant data
59865-13-3, Ciclosporin (see Cyclosporine)
79217-60-0
59865-13-3, Cyclosporine 1 50, 100A 2012
79217-60-0
59820-43-8 HC Yellow No. 4 3 57 1993
598-55-0 Methyl carbamate 3 12, Sup 7 1987
59536-65-1 Polybrominated biphenyls 2A 41, Sup 7, 2016 NB Overall evaluation
107 upgraded to Group 2A
with supporting
evidence from other
relevant data, namely
mechanistic similarity
with polychlorinated
biphenyls classified in
 No CAS. Agente Grupo Volumen Año Información adicional
Group 1
593-70-4 Chlorofluoromethane 3 41, Sup 7, 1999
71
593-60-2 Vinyl bromide 2A 39, Sup 7, 2008 NB (1) Overall
71, 97 evaluation upgraded to
Group 2A based on
mechanistic and other
relevant data; (2) For
practical purposes, vinyl
bromide should be
considered to act
similarly to the human
carcinogen vinyl
chloride
59277-89-3 Aciclovir 3 76 2000
592-62-1 Methylazoxymethanol acetate 2B 10, Sup 7 1987
59-89-2 N-Nitrosomorpholine 2B 17, Sup 7 1987
59-87-0 Nitrofural (Nitrofurazone) 3 50 1990
59-05-2 Methotrexate 3 26, Sup 7 1987
581-89-5 2-Nitronaphthalene 3 46 1989
58-93-5 Hydrochlorothiazide 2B 50, 108 2016
58-89-9 Lindane (see also Hexachlorocyclohexanes) 1 113 2018
58-55-9 Theophylline 3 51 1991
58-14-0 Pyrimethamine 3 13, Sup 7 1987
58-08-2 Caffeine 3 51 1991
57835-92-4 4-Nitropyrene 2B 46, 105 2014
57465-28-8 3,4,5,3’,4’-Pentachlorobiphenyl (PCB-126) 1 100F 2012 See Polychlorinated
biphenyls, dioxin-like,
with a TEF according to
WHO
57117-31-4 2,3,4,7,8-Pentachlorodibenzofuran 1 100F 2012 NB Overall evaluation
upgraded to Group 1
based on mechanistic
and other relevant data
57018-52-7 1-tert-Butoxypropan-2-ol 2B 88, 119 2019
57-88-5 Cholesterol 3 31, Sup 7 1987
57-74-9 Chlordane 2B Sup 7, 53, 2001
79
57-68-1 Sulfamethazine 3 79 2001 NB Overall evaluation
downgraded to Group 3
with supporting
evidence from other
relevant data
57-57-8 beta-Propiolactone 2B 4, Sup 7, 1999
71
57-41-0 Phenytoin 2B Sup 7, 66 1996
57-39-6 Tris(2-methyl-1-aziridinyl)phosphine oxide 3 9, Sup 7 1987
57-14-7 1,1-Dimethylhydrazine 2B 4, Sup 7, 1999
71
57-06-7 Allyl isothiocyanate 3 73, Sup 7 1999
569-64-2, Malachite green (see also Leucomalachite 3 129 2022
14426-28-9, green) online
2437-29-8
569-61-9 CI Basic Red 9 2B 57, 99 2010
 No CAS. Agente Grupo Volumen Año Información adicional
56894-91-8 1,4-Bis(chloromethoxymethyl)benzene 3 15, Sup 7, 1999
71
563-47-3 3-Chloro-2-methylpropene, technical grade 2B 63, 115 2018
563-41-7 Semicarbazide hydrochloride 3 12, Sup 7 1987
562-10-7 Doxylamine succinate 3 79 2001
56-75-7 Chloramphenicol 2A Sup 7, 50 1990 NB Overall evaluation
upgraded to Group 2A
with supporting
evidence from other
relevant data
56-55-3 Benz[a]anthracene 2B 92, Sup 7 2010
56-53-1 Diethylstilbestrol 1 21, Sup 7, 2012
100A
56-38-2 Parathion 2B 30, Sup 7, 2017
112
56-25-7 Cantharidin 3 10, Sup 7 1987
56-23-5 Carbon tetrachloride 2B 20, Sup 7, 1999
71
56-04-2 Methylthiouracil 2B Sup 7, 79 2001
5589-96-8 Bromochloroacetic acid 2B 101 2013
556-52-5 Glycidol 2A 77 2000 NB Overall evaluation
upgraded to Group 2A
with supporting
evidence from other
relevant data
55557-02-3 N-Nitrosoguvacoline 3 Sup 7, 85 2004
55557-01-2 N-Nitrosoguvacine 3 Sup 7, 85 2004
555-84-0 1-[(5-Nitrofurfurylidene)amino]-2- 2B 7, Sup 7 1987
imidazolidinone
5522-43-0 1-Nitropyrene 2A Sup 7, 46, 2014 NB Overall evaluation
105 upgraded to Group 2A
with supporting
evidence from other
relevant data
551-74-6 Mannomustine dihydrochloride 3 9, Sup 7 1987
55-98-1 1,4-Butanediol dimethanesulfonate (see
Busulfan)
55-98-1 Busulfan 1 4, Sup 7, 2012
100A
55-98-1 Myleran (see Busulfan)
55-18-5 N-Nitrosodiethylamine 2A 17, Sup 7 1987 NB Overall evaluation
upgraded to Group 2A
with supporting
evidence from other
relevant data
548-62-9 Gentian violet (see also Leucogentian violet) 2B 129 2022
online
54749-90-5 Chlorozotocin 2A 50 1990 NB Overall evaluation
upgraded to Group 2A
with supporting
evidence from other
relevant data
5456-28-0 Ethyl selenac 3 12, Sup 7 1987
545-55-1 Tris(1-aziridinyl)phosphine oxide 3 9, Sup 7 1987
 No CAS. Agente Grupo Volumen Año Información adicional
545-06-2 Trichloroacetonitrile 3 52, 71 1999
5431-33-4 Glycidyl oleate 3 11, Sup 7 1987
542-88-1, Bis(chloromethyl)ether; chloromethyl methyl 1 4, Sup 7, 2012
107-30-2 ether (technical-grade) 100F
542-78-9 Malonaldehyde 3 36, Sup 7, 1999
71
542-75-6 1,3-Dichloropropene (technical-grade) 2B 41, Sup 7, 1999
71
542-56-3 Isobutyl nitrite 2B 122 2019
541-73-1 meta-Dichlorobenzene 3 73 1999
540-73-8 1,2-Dimethylhydrazine 2A 4, Sup 7, 1999 NB Overall evaluation
71 upgraded to Group 2A
with supporting
evidence from other
relevant data
54-85-3 Isonicotinic acid hydrazide (Isoniazid) 3 4, Sup 7 1987
54-31-9 Furosemide (Frusemide) 3 50 1990
54-05-7 Chloroquine 3 13, Sup 7 1987
53973-98-1 Carrageenan, degraded (Poligeenan) 2B 31, Sup 7 1987
53973-98-1 Poligeenan (see Carrageenan, degraded)
5385-75-1 Dibenzo[a,e]fluoranthene 3 Sup 7, 92 2010
536-33-4 Ethionamide 3 13, Sup 7 1987
532-82-1 Chrysoidine 3 8, Sup 7 1987
531-82-8 N-[4-(5-Nitro-2-furyl)-2-thiazolyl]acetamide 2B 7, Sup 7 1987
531-76-0 Merphalan 2B 9, Sup 7 1987
5307-14-2 1,4-Diamino-2-nitrobenzene 3 Sup 7, 57 1993
53-70-3 Dibenz[a,h]anthracene 2A Sup 7, 92 2010 NB Overall evaluation
upgraded to Group 2A
with supporting
evidence from other
relevant data
53-03-2 Prednisone 3 26, Sup 7 1987
52918-63-5 Deltamethrin 3 53 1991
52645-53-1 Permethrin 3 53 1991
523-50-2 Angelicin plus ultraviolet A radiation 3 40, Sup 7 1987
523-44-4 CI Acid Orange 20 3 8, Sup 7 1987
523-44-4 Orange I (see CI Acid Orange 20)
520-18-3 Kaempferol 3 31, Sup 7 1987
52-68-6 Trichlorfon 3 30, Sup 7 1987
52-46-0 Apholate 3 9, Sup 7 1987
52-24-4 Thiotepa 1 Sup 7, 50, 2012
100A
52-01-7 Spironolactone 3 Sup 7, 79 2001
518-75-2 Citrinin 3 40, Sup 7 1987
51630-58-1 Fenvalerate 3 53 1991
5160-02-1 D & C Red No. 9 3 Sup 7, 57 1993
51481-61-9 Cimetidine 3 50 1990
5141-20-8 Light Green SF 3 16, Sup 7 1987
5131-60-2 4-Chloro-meta-phenylenediamine 3 27, Sup 7 1987
513-37-1 1-Chloro-2-methylpropene 2B 63 1995
 No CAS. Agente Grupo Volumen Año Información adicional
51264-14-3 Amsacrine 2B 76 2000
510-15-6 Chlorobenzilate 3 30, Sup 7 1987
51-79-6 Ethyl carbamate (Urethane) 2A 7, Sup 7, 2010
96
51-75-2 Nitrogen mustard 2A 9, Sup 7 1987
51-52-5 Propylthiouracil 2B Sup 7, 79 2001
51-21-8 5-Fluorouracil 3 26, Sup 7 1987
51-18-3 2,4,6-Tris(1-aziridinyl)-s-triazine 3 9, Sup 7 1987
51-03-6 Piperonyl butoxide 3 30, Sup 7 1987
51-02-5 Pronetalol hydrochloride 3 13, Sup 7 1987
50926-11-9 Indium tin oxide 2B 118 2018
online
509-14-8 Tetranitromethane 2B 65 1996
505-60-2 Mustard gas (see Sulfur mustard)
505-60-2 Sulfur mustard 1 9, Sup 7, 2012
100F
501-30-4 Kojic acid 3 79 2001
50-76-0 Actinomycin D 3 10, Sup 7 1987
50-55-5 Reserpine 3 24, Sup 7 1987
50-44-2 6-Mercaptopurine 3 26, Sup 7 1987
50-41-9 Clomiphene citrate 3 21, Sup 7 1987
50-33-9 Phenylbutazone 3 13, Sup 7 1987
50-32-8 Benzo[a]pyrene 1 Sup 7, 92, 2012 NB Overall evaluation
100F upgraded to Group 1
based on mechanistic
and other relevant data
50-29-3 DDT (4,4'-dichlorodiphenyltrichloroethane) 2A Sup 7, 53, 2018
113
50-18-0, Cyclophosphamide 1 26, Sup 7, 2012
6055-19-2 100A
50-07-7 Mitomycin C 2B 10, Sup 7 1987
50-06-6 Phenobarbital 2B Sup 7, 79 2001
50-00-0 Formaldehyde 1 Sup 7, 62, 2012
88, 100F
494-38-2 Acridine orange 3 16, Sup 7 1987
494-03-1 N,N-Bis(2-chloroethyl)-2-naphthylamine (see
Chlornaphazine)
494-03-1 Chlornaphazine 1 4, Sup 7, 2012
100A
493-52-7 Methyl red 3 8, Sup 7 1987
492-80-8 Auramine 2B 1, Sup 7, 2012
99, 100F
492-17-1 2,4'-Diphenyldiamine 3 16, Sup 7 1987
484-20-8 5-Methoxypsoralen 2A 40, Sup 7 1987 NB Overall evaluation
upgraded to Group 2A
with supporting
evidence from other
relevant data
480-81-9 Seneciphylline 3 10, Sup 7 1987
480-54-6 Retrorsine 3 10, Sup 7 1987
4680-78-8 Guinea Green B 3 16, Sup 7 1987
 No CAS. Agente Grupo Volumen Año Información adicional
4657-93-6 5-Aminoacenaphthene 3 16, Sup 7 1987
4549-40-0 N-Nitrosomethylvinylamine 2B 17, Sup 7 1987
4548-53-2 Ponceau SX 3 8, Sup 7 1987
446-86-6 Azathioprine 1 26, Sup 7, 2012
100A
443-48-1 Metronidazole 2B 13, Sup 7 1987
439-14-5 Diazepam 3 Sup 7, 66 1996
4342-03-4 Dacarbazine 2B 26, Sup 7 1987
42397-65-9 1,8-Dinitropyrene 2B Sup 7, 46, 2014
105
42397-64-8 1,6-Dinitropyrene 2B 46, 105 2014
420-12-2 Ethylene sulfide 3 11, Sup 7 1987
4170-30-3 Crotonaldehyde 2B 63 (corr. 2021
65), 128 online
409-21-2 Silicon carbide whiskers 2A 111 2017
40762-15-0 Doxefazepam 3 66 1996
4063-41-6 4,5'-Dimethylangelicin plus ultraviolet A 3 Sup 7 1987
radiation
396-01-0 Triamterene 2B 108 2016
3902-71-4 4,5',8-Trimethylpsoralen 3 40, Sup 7 1987
38571-73-2 1,2,3-Tris(chloromethoxy)propane 3 15, Sup 7, 1999
71
3844-45-9 Brilliant Blue FCF, disodium salt 3 16, Sup 7 1987
3795-88-8 5-(Morpholinomethyl)-3-[(5-nitrofurfurylidene) 2B 7, Sup 7 1987
amino]-2-oxazolidinone
3778-73-2 Isophosphamide 3 26, Sup 7 1987
3771-19-5 Nafenopin 2B 24, Sup 7 1987
37620-20-5 N'-Nitrosoanabasine (NAB) 3 37, Sup 7, 2007
89
3761-53-3 Ponceau MX 2B 8, Sup 7 1987
37319-17-8 Pentosan polysulfate sodium 2B 108 2016
3697-24-3 5-Methylchrysene 2B Sup 7, 92 2010
3688-53-7 AF-2 [2-(2-Furyl)-3-(5-nitro-2-furyl)acrylamide] 2B 31, Sup 7 1987
366-70-1 Procarbazine hydrochloride 2A 26, Sup 7 1987 NB Overall evaluation
upgraded to Group 2A
with supporting
evidence from other
relevant data
3570-75-0 2-(2-Formylhydrazino)-4-(5-nitro-2- 2B 7, Sup 7 1987
furyl)thiazole
3567-69-9 Carmoisine 3 8, Sup 7 1987
3564-09-8 Ponceau 3R 2B 8, Sup 7 1987
33543-31-6 2-Methylfluoranthene 3 Sup 7, 92 2010
3351-32-4 2-Methylchrysene 3 Sup 7, 92 2010
3351-31-3 3-Methylchrysene 3 Sup 7, 92 2010
3351-30-2 4-Methylchrysene 3 Sup 7, 92 2010
3351-28-8 1-Methylchrysene 3 Sup 7, 92 2010
335-67-1 Perfluorooctanoic acid (PFOA) 2B 110 2017
33419-42-0, Etoposide in combination with cisplatin and 1 76, 100A 2012
15663-27-1, bleomycin
 No CAS. Agente Grupo Volumen Año Información adicional
11056-06-7
33419-42-0 Etoposide 1 76, 100A 2012 NB Overall evaluation
upgraded to Group 1
based on mechanistic
and other relevant data
334-88-3 Diazomethane 3 7, Sup 7 1987
333-41-5 Diazinon 2A 112 2017 NB Overall evaluation
upgraded to Group 2A
based on mechanistic
evidence
33229-34-4 HC Blue No. 2 3 57 1993
331-39-5 Caffeic acid 2B 56 1993
3296-90-0 2,2-Bis(bromomethyl)propane-1,3-diol 2B 77 2000
3252-43-5 Dibromoacetonitrile 2B 52, 71, 2013
101
320-67-2 Azacitidine 2A 50 1990 NB Overall evaluation
upgraded to Group 2A
with supporting
evidence from other
relevant data
3173-72-6 1,5-Naphthalene diisocyanate 3 19, Sup 7, 1999
71
315-22-0 Monocrotaline 2B 10, Sup 7 1987
315-18-4 Zectran 3 12, Sup 7 1987
314-13-6 Evans blue 3 8, Sup 7 1987
313-67-7 Aristolochic acid 1 82, 100A 2012 NB Overall evaluation
upgraded to Group 1
based on mechanistic
and other relevant data
313-67-7 Aristolochic acid, plants containing 1 82, 100A 2012
3118-97-6 Sudan II 3 8, Sup 7 1987
309-00-2 Aldrin (see Dieldrin, and aldrin metabolized to
dieldrin)
308076-74-6 Silicon carbide, fibrous 2B 111 2017
308068-56-6 Carbon nanotubes, multiwalled MWCNT-7 2B 111 2017
308068-56-6 Carbon nanotubes, multiwalled, other than 3 111 2017
MWCNT-7
308068-56-6 Carbon nanotubes, single-walled 3 111 2017
308068-56-6 Multiwalled carbon nanotubes MWCNT-7 (see
Carbon nanotubes, multiwalled MWCNT-7)
308068-56-6 Multiwalled carbon nanotubes other than
MWCNT-7 (see Carbon nanotubes,
multiwalled, other than MWCNT-7)
308068-56-6 Single-walled carbon nanotubes (see Carbon
nanotubes, single-walled)
3068-88-0 beta-Butyrolactone 2B 11, Sup 7, 1999
71
30516-87-1 Zidovudine (AZT) 2B 76 2000
305-03-3 Chlorambucil 1 26, Sup 7, 2012
100A
30310-80-6 N-Nitrosohydroxyproline 3 17, Sup 7 1987
303-47-9 Ochratoxin A 2B Sup 7, 56 1993
303-34-4 Lasiocarpine 2B 10, Sup 7 1987
 No CAS. Agente Grupo Volumen Año Información adicional
302-17-0 Chloral hydrate 2A 63, 84, 2014
106
302-01-2 Hydrazine 2A 4, Sup 7, 2018
71, 115
3018-12-0 Dichloroacetonitrile 3 52, 71 1999
29975-16-4 Estazolam 3 66 1996
299-75-2 Treosulfan 1 26, Sup 7, 2012
100A
298-81-7 Methoxsalen (8-methoxypsoralen) plus 1 24, Sup 7, 2012
ultraviolet A radiation 100A
298-00-0 Methyl parathion 3 30, Sup 7 1987
29767-20-2 Teniposide 2A 76 2000 NB Overall evaluation
upgraded to Group 2A
with supporting
evidence from other
relevant data
2973-10-6 Diisopropyl sulfate 2B 54, 71 1999
2955-38-6 Prazepam 3 66 1996
29291-35-8 N-Nitrosofolic acid 3 17, Sup 7 1987
29069-24-7 Prednimustine 3 50 1990
2871-01-4 HC Red No. 3 3 57 1993
28434-86-8 3,3'-Dichloro-4,4'-diaminodiphenyl ether 2B 16, Sup 7 1987
28407-37-6 CI Direct Blue 218 2B 129 2022
online
2835-39-4 Allyl isovalerate 3 36, Sup 7, 1999
71
2832-40-8 Disperse Yellow 3 3 48 1990
2784-94-3 HC Blue No. 1 2B 57 1993
2783-94-0 Sunset Yellow FCF 3 8, Sup 7 1987
2757-90-6 Agaritine 3 31, Sup 7 1987
27208-37-3 Cyclopenta[cd]pyrene 2A Sup 7, 92 2010 NB Overall evaluation
upgraded to Group 2A
with supporting
evidence from other
relevant data
271-89-6 Benzofuran 2B 63 1995
26782-43-4 Hydroxysenkirkine 3 10, Sup 7 1987
26471-62-5 Toluene diisocyanates 2B 39, Sup 7, 1999
71
2646-17-5 Oil Orange SS 2B 8, Sup 7 1987
26308-28-1 Ripazepam 3 66 1996
262-12-4 Dibenzo-para-dioxin 3 69 1997
26148-68-5 A-alpha-C (2-Amino-9H-pyrido[2,3-b]indole) 2B 40, Sup 7 1987
2602-46-2 CI Direct Blue 6 (see Benzidine, dyes
metabolized to)
25962-77-0 trans-2-[(Dimethylamino)methylimino]-5-[2-(5- 2B 7, Sup 7 1987
nitro-2-furyl)-vinyl]-1,3,4-oxadiazole
25812-30-0 Gemfibrozil 3 66 1996
25732-74-5 Acepyrene (3,4-dihydrocyclopenta[cd]pyrene) 3 92 2010
25038-54-4 Nylon 6 3 19, Sup 7 1987
25013-16-5 Butylated hydroxyanisole (BHA) 2B 40, Sup 7 1987
 No CAS. Agente Grupo Volumen Año Información adicional
25013-15-4 Vinyl toluene 3 60 1994
24938-64-5 para-Aramid fibrils 3 68 1997
2475-45-8 Disperse Blue 1 2B 48 1990
24560-98-3 cis-9,10-Epoxystearic acid 3 11, Sup 7, 1999
71
2432-99-7 11-Aminoundecanoic acid 3 39, Sup 7 1987
243-17-4 Benzo[b]fluorene 3 92, Sup 7 2010
2429-74-5 CI Direct Blue 15 2B 57 1993
2426-08-6 1-Butyl glycidyl ether 2B 125 2020
online
2425-85-6 CI Pigment Red 3 3 57 1993
2425-06-1 Captafol 2A 53 1991 NB Overall evaluation
upgraded to Group 2A
with supporting
evidence from other
relevant data
239-35-0 Benzo[b]naphtho[2,1-d]thiophene 3 103 2013
2386-90-5 Bis(2,3-epoxycyclopentyl)ether 3 47, 71 1999
2385-85-5 Mirex 2B 20, Sup 7 1987
238-84-6 Benzo[a]fluorene 3 92, Sup 7 2010
23746-34-1 Potassium bis(2- 3 12, Sup 7 1987
hydroxyethyl)dithiocarbamate
23537-16-8 Rugulosin 3 40, Sup 7 1987
2353-45-9 Fast Green FCF 3 16, Sup 7 1987
23255-93-8 Hycanthone mesylate 3 13, Sup 7 1987
23246-96-0 Riddelliine 2B 10, Sup 7, 2002
82
23214-92-8 Adriamycin 2A 10, Sup 7 1987 NB Overall evaluation
upgraded to Group 2A
with supporting
evidence from other
relevant data
2318-18-5 Senkirkine 3 31, Sup 7 1987
2303-16-4 Diallate 3 30, Sup 7 1987
22975-76-4 4,4'-Dimethylangelicin plus ultraviolet A 3 Sup 7 1987
radiation
22966-79-6 Oestradiol mustard 3 9, Sup 7 1987
226-36-8 Dibenz[a,h]acridine 2B 32, Sup 7, 2013
103
22571-95-5 Symphytine 3 31, Sup 7 1987
22506-53-2 3,9-Dinitrofluoranthene 2B 46, 65, 2014
105
225-51-4 Benz[c]acridine 3 32, Sup 7, 2013
103
225-11-6 Benz[a]acridine 3 32, Sup 7, 2013
103
2243-62-1 1,5-Naphthalenediamine 3 27, Sup 7 1987
224-53-3 Dibenz[c,h]acridine 2B 103 2013 NB Overall evaluation
upgraded to Group 2B
with supporting
evidence from other
relevant data
 No CAS. Agente Grupo Volumen Año Información adicional
224-42-0 Dibenz[a,j]acridine 2A 32, Sup 7, 2013 NB Overall evaluation
103 upgraded to Group 2A
with supporting
evidence from other
relevant data
224-41-9 Dibenz[a,j]anthracene 3 Sup 7, 92 2010
22398-80-7 Indium phosphide 2A 86 2006 NB Overall evaluation
upgraded to Group 2A
22349-59-3 1,4-Dimethylphenanthrene 3 Sup 7, 92 2010
22248-79-9 Tetrachlorvinphos 2B 30, Sup 7, 2017
112
21884-44-6 Luteoskyrin 3 10, Sup 7 1987
218-01-9 Chrysene 2B 92 2010
217-59-4 Triphenylene 3 Sup 7, 92 2010
2168-68-5 Bis(1-aziridinyl)morpholinophosphine sulfide 3 9, Sup 7 1987
2164-17-2 Fluometuron 3 30, Sup 7 1987
215-58-7 Dibenz[a,c]anthracene 3 Sup 7, 92 2010
214-17-5 Benzo[b]chrysene 3 92 2010
213-46-7 Picene 3 92 2010
21259-20-1 T2-Trichothecene 3 31, Sup 7 1987
211-91-6 Benz[l]aceanthrylene 3 92 2010
20941-65-5 Ethyl tellurac 3 12, Sup 7 1987
20830-81-3 Daunomycin 2B 10, Sup 7 1987
20830-75-5 Digoxin 2B 108 2016
207-83-0 13H-Dibenzo[a,g]fluorene 3 92 2010
207-08-9 Benzo[k]fluoranthene 2B 92 2010
2068-78-2 Vincristine sulfate 3 26, Sup 7 1987
206-44-0 Fluoranthene 3 Sup 7, 92 2010
20589-63-3 3-Nitroperylene 3 46 1989
205-99-2 Benzo[b]fluoranthene 2B 92 2010
205-82-3 Benzo[j]fluoranthene 2B 92 2010
205-12-9 Benzo[c]fluorene 3 92, Sup 7 2010
203-33-8 Benzo[a]fluoranthene 3 92, Sup 7 2010
203-20-3 Naphtho[2,1-a]fluoranthene 3 92 2010
203-12-3 Benzo[ghi]fluoranthene 3 92, Sup 7 2010
20268-51-3 7-Nitrobenz[a]anthracene 3 46 1989
202-98-2 4H-Cyclopenta[def]chrysene 3 92 2010
202-94-8 11H-Benz[bc]aceanthrylene 3 92 2010
202-33-5 Benz[j]aceanthrylene 2B 92 2010 NB Overall evaluation
upgraded to Group 2B
with supporting
mechanistic and other
relevant data
20073-24-9 3-Carbethoxypsoralen 3 40, Sup 7 1987
198-55-0 Perylene 3 Sup 7, 92 2010
196-78-1 Benzo[g]chrysene 3 92 2010
1954-28-5 Triethylene glycol diglycidyl ether 3 11, Sup 7, 1999
71
195-19-7 Benzo[c]phenanthrene 2B 92, Sup 7 2010 NB Overall evaluation
upgraded to Group 2B
 No CAS. Agente Grupo Volumen Año Información adicional
with supporting
evidence from other
relevant data
194-59-2 7H-Dibenzo[c,g]carbazole 2B 32, Sup 7, 2013
103
1937-37-7 CI Direct Black 38 (see Benzidine, dyes
metabolized to)
1936-15-8 CI Orange G 3 8, Sup 7 1987
1936-15-8 Orange G (see CI Orange G)
193-39-5 Indeno[1,2,3-cd]pyrene 2B Sup 7, 92 2010
193-09-9 Naphtho[2,3-e]pyrene 3 92 2010
192-97-2 Benzo[e]pyrene 3 92, Sup 7 2010
192-65-4 Dibenzo[a,e]pyrene 3 Sup 7, 92 2010
192-51-8 Dibenzo[e,l]pyrene 3 92 2010
192-47-2 Dibenzo[h,rst]pentaphene 3 Sup 7, 92 2010
1918-02-1 Picloram 3 53 1991
1912-24-9 Atrazine 3 53, 73 1999 NB Overall evaluation
downgraded to Group 3
with supporting
evidence from other
relevant data
191-30-0 Dibenzo[a,l]pyrene 2A Sup 7, 92 2010 NB Overall evaluation
upgraded to Group 2A
with supporting
evidence from other
relevant data
191-26-4 Anthanthrene 3 92, Sup 7 2010
191-24-2 Benzo[ghi]perylene 3 92, Sup 7 2010
191-07-1 Coronene 3 32, Sup 7, 1987
92
1897-45-6 Chlorothalonil 2B Sup 7, 73 1999
189-64-0 Dibenzo[a,h]pyrene 2B Sup 7, 92 2010
189-55-9 Dibenzo[a,i]pyrene 2B 92 2010
18883-66-4 Streptozotocin 2B 17, Sup 7 1987
18540-29-9 Chromium (VI) compounds 1 Sup 7, 49, 2012
100C
1836-75-5 Nitrofen (technical-grade) 2B 30, Sup 7 1987
1746-01-6 2,3,7,8-Tetrachlorodibenzo-para-dioxin 1 Sup 7, 69, 2012
100F
17117-34-9 3-Nitrobenzanthrone 2B 105 2014 NB Overall evaluation
upgraded to Group 2B
with supporting
evidence from other
relevant data
1706-01-0 3-Methylfluoranthene 3 Sup 7, 92 2010
1705-85-7 6-Methylchrysene 3 Sup 7, 92 2010
16984-48-8 Fluorides (inorganic, used in drinking-water) 3 27, Sup 7 1987
1694-09-3 Benzyl violet 4B 2B 16, Sup 7 1987
1689-82-3 4-Hydroxyazobenzene 3 8, Sup 7 1987
1675-54-3 Bisphenol A diglycidyl ether (Araldite) 3 47, 71 1999
16568-02-8 Gyromitrin 3 31, Sup 7 1987
16543-55-8, N'-Nitrosonornicotine (NNN) and 4-(N- 1 Sup 7, 89, 2012 NB Overall evaluation
 No CAS. Agente Grupo Volumen Año Información adicional
64091-91-4 Nitrosomethylamino)-1-(3-pyridyl)-1-butanone 100E upgraded to Group 1
(NNK) based on mechanistic
and other relevant data
1634-04-4 Methyl tert-butyl ether 3 73 1999
1615-80-1 1,2-Diethylhydrazine 2B 4, Sup 7, 1999
71
16071-86-6 CI Direct Brown 95 (see Benzidine, dyes
metabolized to)
16065-83-1 Chromium (III) compounds 3 49 1990
1582-09-8 Trifluralin 3 53 1991
15721-02-5 2,2',5,5'-Tetrachlorobenzidine 3 27, Sup 7 1987
15663-27-1 Cisplatin 2A 26, Sup 7 1987 NB Overall evaluation
upgraded to Group 2A
with supporting
evidence from other
relevant data
15625-89-5 Trimethylolpropane triacrylate, technical 2B 122 2019
grade
156-51-4 Phenelzine sulfate 3 24, Sup 7 1987
156-10-5 para-Nitrosodiphenylamine 3 27, Sup 7 1987
15503-86-3 Isatidine 3 10, Sup 7 1987
15501-74-3 Sepiolite 3 Sup 7, 68 1997
154-93-8 Bischloroethyl nitrosourea (BCNU) 2A 26, Sup 7 1987
15262-20-1 Radium-228 and its decay products 1 78, 100D 2012
151-56-4 Aziridine 2B 9, Sup 7, 1999 NB Overall evaluation
71 upgraded to Group 2B
with supporting
evidence from other
relevant data
15086-94-9 Eosin 3 15, Sup 7 1987
150-69-6 Dulcin 3 12, Sup 7 1987
150-68-5 Monuron 3 Sup 7, 53 1991
150-13-0 para-Aminobenzoic acid 3 16, Sup 7 1987
14901-08-7 Cycasin 2B 10, Sup 7 1987
149-30-4 2-Mercaptobenzothiazole 2A 115 2018
149-29-1 Patulin 3 40, Sup 7 1987
14808-60-7 Silica dust, crystalline, in the form of quartz or 1 Sup 7, 68, 2012
cristobalite 100C
14807-96-6 Talc containing asbestiform fibres (see 42, Sup 7 1987
Asbestos)
14807-96-6 Talc not containing asbestos or asbestiform 3 42, Sup 7, 2010
fibres 93
14807-96-6 Talc-based body powder (perineal use of) 2B 93 2010
148-82-3 Melphalan 1 9, Sup 7, 2012
100A
148-24-3 8-Hydroxyquinoline 3 13, Sup 7 1987
148-18-5 Sodium diethyldithiocarbamate 3 12, Sup 7 1987
1464-53-5 1,2:3,4-Diepoxybutane (see Monographs on 11, Sup 7 1987
1,3-Butadiene)
14596-37-3 Phosphorus-32, as phosphate 1 78, 100D 2012
14484-64-1 Ferbam 3 12, Sup 7 1987
 No CAS. Agente Grupo Volumen Año Información adicional
144-34-3 Methyl selenac 3 12, Sup 7 1987
143-67-9 Vinblastine sulfate 3 26, Sup 7 1987
143-50-0 Chlordecone (Kepone) 2B 20, Sup 7 1987
142-83-6 2,4-Hexadienal 2B 101 2013
142-04-1 Aniline hydrochloride (see also Aniline) 2A 127 2021
online
141-90-2 Thiouracil 2B Sup 7, 79 2001
141-37-7 3,4-Epoxy-6-methylcyclohexylmethyl-3,4- 3 11, Sup 7, 1999
epoxy-6-methylcyclo-hexanecarboxylate 71
141-32-2 n-Butyl acrylate 3 39, Sup 7, 1999
71
14047-09-7 3,3′,4,4′-Tetrachloroazobenzene 2A 117 2019 NB Overall evaluation
upgraded to Group 2A
1402-68-2 Aflatoxins 1 Sup 7, 56, 2012
82, 100F
1401-55-4 Tannic acid and tannins 3 10, Sup 7 1987
140-88-5 Ethyl acrylate 2B 39, Sup 7, 2019
71, 122
140-57-8 Aramite® 2B 5, Sup 7 1987
140-56-7 para-Dimethylaminoazobenzenediazo sodium 3 8, Sup 7 1987
sulfonate
140-11-4 Benzyl acetate 3 40, Sup 7, 1999
71
13983-17-0 Wollastonite 3 Sup 7, 68 1997
13982-63-3 Radium-226 and its decay products 1 78, 100D 2012
13909-09-6 1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-
nitrosourea (Methyl-CCNU) (see Semustine)
13909-09-6 Semustine [1-(2-Chloroethyl)-3-(4- 1 Sup 7, 2012
methylcyclohexyl)-1-nitrosourea, Methyl- 100A
CCNU]
139-94-6 Nithiazide 3 31, Sup 7 1987
139-65-1 4,4'-Thiodianiline 2B 27, Sup 7 1987
139-13-9 Nitrilotriacetic acid and its salts 2B 48, 73 1999 NB Evaluated as a
group
139-05-9 Cyclamates (sodium cyclamate) 3 Sup 7, 73 1999
138-59-0 Shikimic acid 3 40, Sup 7 1987
137-30-4 Ziram 3 Sup 7, 53 1991
137-26-8 Thiram 3 Sup 7, 53 1991
137-17-7 2,4,5-Trimethylaniline 3 27, Sup 7 1987
136-40-3 Phenazopyridine hydrochloride 2B 24, Sup 7 1987
135-88-6 N-Phenyl-2-naphthylamine 3 16, Sup 7 1987
135-20-6 Cupferron 2B 127 2021
online
13483-18-6 1,2-Bis(chloromethoxy)ethane 3 15; Sup 7, 1999
71
13463-67-7 Titanium dioxide 2B 47, 93 2010
1345-04-6 Antimony trisulfide, see Trivalent antimony
134-32-7 1-Naphthylamine 3 4, Sup 7 1987
134-29-2 ortho-Anisidine hydrochloride (see also ortho- 2A 127 2021
Anisidine) online
1338-16-5 Iron sorbitol-citric acid complex 3 2, Sup 7 1987
 No CAS. Agente Grupo Volumen Año Información adicional
1336-36-3 Polychlorinated biphenyls 1 18, Sup 7, 2016
107
1333-86-4 Carbon black 2B Sup 7, 65, 2010
93
1332-21-4, Asbestos (all forms, including actinolite, 1 14, Sup 7, 2012 NB Mineral substances
12172-73-5, amosite, anthophyllite, chrysotile, crocidolite, 100C (e.g. talc or vermiculite)
12001-29-5, tremolite) that contain asbestos
12001-28-4 should also be regarded
as carcinogenic to
humans *The presence
of an asterisk indicates
that the registration is
for a substance which
CAS does not treat in its
regular CA index
1330-20-7 Xylenes 3 47, 71 1999
133-06-2 Captan 3 30, Sup 7 1987
13292-46-1 Rifampicin 3 24, Sup 7 1987
13256-22-9 N-Nitrososarcosine 2B 17, Sup 7 1987
13233-32-4 Radium-224 and its decay products 1 78, 100D 2012
132-65-0 Dibenzothiophene 3 103 2013
132-27-4 Sodium ortho-phenylphenate 2B Sup 7, 73 1999
1318-02-1 Zeolites other than erionite (clinoptilolite, 3 68 1997
phillipsite,mordenite, non-fibrous Japanese
zeolite, synthetic zeolites)
1317-60-8 Haematite 3 1, Sup 7 1987
1317-42-6 Cobalt(II) sulfide 3 52, 131 In
prep.
1314-62-1 Vanadium pentoxide 2B 86 2006
1313-27-5 Molybdenum trioxide 2B 118 2018
online
131-79-3 Yellow OB 3 8, Sup 7 1987
1309-64-4 Antimony trioxide, see Trivalent antimony
1309-37-1 Ferric oxide 3 1, Sup 7 1987
1308-06-1 Cobalt(II,III) oxide 3 52, 131 In
prep.
1307-96-6 Cobalt(II) oxide 2B 52, 131 In
prep.
13045-94-8 Medphalan 3 9, Sup 7 1987
1303-00-0 Gallium arsenide (see Arsenic and inorganic 86, 100C 2012
arsenic compounds)
13010-47-4 1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea 2A 26, Sup 7 1987 NB Overall evaluation
(CCNU) upgraded to Group 2A
with supporting
evidence from other
relevant data
129-73-7 Leucomalachite green (see also Malachite 2B 129 2022
green) online
129-43-1 1-Hydroxyanthraquinone 2B 82 2002
129-20-4 Oxyphenbutazone 3 13, Sup 7 1987
129-17-9 Blue VRS 3 16, Sup 7 1987
129-15-7 2-Methyl-1-nitroanthraquinone (uncertain 2B 27, Sup 7 1987
purity)
 No CAS. Agente Grupo Volumen Año Información adicional
129-00-0 Pyrene 3 Sup 7, 92 2010
128-66-5 Vat Yellow 4 3 48 1990
128-37-0 Butylated hydroxytoluene (BHT) 3 40, Sup 7 1987
127-69-5 Sulfafurazole (Sulfisoxazole) 3 24, Sup 7 1987
127-19-5 N,N-Dimethylacetamide 2B 123 2020
online
127-18-4 Tetrachloroethylene (Perchloroethylene) 2A Sup 7, 63, 2014
106
127-07-1 Hydroxyurea 3 76 2000
12663-46-6 Cyclochlorotine 3 10, Sup 7 1987
126-99-8 Chloroprene 2B Sup 7, 71 1999
126-85-2 Nitrogen mustard N-oxide 2B 9, Sup 7 1987
126-72-7 Tris(2,3-dibromopropyl) phosphate 2A 20, Sup 7, 1999 NB Overall evaluation
71 upgraded to Group 2A
with supporting
evidence from other
relevant data
126-07-8 Griseofulvin 2B Sup 7, 79 2001
125-33-7 Primidone 2B 108 2016
12427-38-2 Maneb 3 12, Sup 7 1987
124-58-3 Methylarsonic acid 2B 100C 2012
124-58-3 Monomethylarsonic acid (see Methylarsonic
acid)
124-48-1 Chlorodibromomethane 3 52, 71 1999
123-91-1 1,4-Dioxane 2B 11, Sup 7, 1999
71
123-35-3 β-Myrcene 2B 119 2019
123-33-1 Maleic hydrazide 3 4, Sup 7 1987
123-31-9 Hydroquinone 3 15, Sup 7, 1999
71
122320-73-4 Rosiglitazone 3 108 2016
122-66-7 1,2-Diphenylhydrazine 2B 130 In
prep.
122-60-1 Phenyl glycidyl ether 2B 47, 71 1999
122-42-9 Propham 3 12, Sup 7 1987
122-39-4 Diphenylamine 2B 130 In
prep.
122-34-9 Simazine 3 53, 73 1999
12192-57-3 Aurothioglucose 3 13, Sup 7 1987
12174-11-7 Attapulgite (see Palygorskite)
12174-11-7 Palygorskite (Attapulgite) (long fibres, > 5 2B 68 1997
micrometres)
12174-11-7 Palygorskite (Attapulgite)(short fibres, < 5 3 68 1997
micrometres)
12122-67-7 Zineb 3 12, Sup 7 1987
121-88-0 2-Amino-5-nitrophenol 3 57 1993
121-75-5 Malathion 2A 30, Sup 7, 2017
112
121-69-7 N,N-Dimethylaniline 3 57 1993
121-66-4 2-Amino-5-nitrothiazole 3 31, Sup 7 1987
 No CAS. Agente Grupo Volumen Año Información adicional
121-14-2 2,4-Dinitrotoluene 2B 65 1996
12070-12-1, Tungsten carbide with cobalt metal (see
7440-48-4 Cobalt metal with tungsten carbide)
12001-79-5 Vitamin K substances 3 76 2000
120-80-9 Catechol 2B 15, Sup 7, 1999
71
120-71-8 para-Cresidine 2B 27, Sup 7 1987
120-58-1 Isosafrole 3 10, Sup 7 1987
120-12-7 Anthracene 3 92, Sup 7 2010
119-93-7 3,3'-Dimethylbenzidine (ortho-Tolidine) 2B 1, Sup 7 1987
119-90-4 3,3'-Dimethoxybenzidine (ortho-Dianisidine) 2B 4, Sup 7 1987
119-61-9 Benzophenone 2B 101 2013
119-34-6 4-Amino-2-nitrophenol 3 16, Sup 7 1987
118399-22-7 Nodularins 3 94 2010
118-96-7 2,4,6-Trinitrotoluene 3 65 1996
118-92-3 Anthranilic acid 3 16, Sup 7 1987
118-74-1 Hexachlorobenzene 2B Sup 7, 79 2001
117-81-7 Bis(2-ethylhexyl) phthalate (see Di(2-
ethylhexyl) phthalate)
117-81-7 Di(2-ethylhexyl)phthalate 2B Sup 7, 77, 2013
101
117-79-3 2-Aminoanthraquinone 3 27, Sup 7 1987
117-39-5 Quercetin 3 Sup 7, 73 1999
117-10-2 Dantron (Chrysazin; 1,8- 2B 50 1990
Dihydroxyanthraquinone)
116355-83-0 Fusarium moniliforme, toxins derived from 2B 56 1993
(fumonisin B1, fumonisin B2, and fusarin C)
116355-83-0 Fumonisin B1 2B 82 2002
1163-19-5 Decabromodiphenyl oxide 3 48, 71 1999
116-14-3 Tetrafluoroethylene 2A 19, Sup 7, 2017 NB Overall evaluation
71, 110 upgraded to Group 2A
on the basis of
sufficient evidence in
experimental animals
with a striking and
atypical pattern of
tumours
116-06-3 Aldicarb 3 53 1991
115-96-8 Tris(2-chloroethyl) phosphate 3 48, 71 1999
115-32-2 Dicofol 3 30, Sup 7 1987
115-28-6 Chlorendic acid 2B 48 1990
115-07-1 Propylene 3 Sup 7, 60 1994
115-02-6 Azaserine 2B 10, Sup 7 1987
1143-38-0 Dithranol 3 13; Sup 7 1987
1120-71-4 1,3-Propane sultone 2A 4, Sup 7, 2017 NB Overall evaluation
71, 110 upgraded to Group 2A
with supporting
evidence from other
relevant data
1116-54-7 N-Nitrosodiethanolamine 2B 17, Sup 7, 2000
77
 No CAS. Agente Grupo Volumen Año Información adicional
111189-32-3 Naphtho[1,2-b]fluoranthene 3 92 2010
111025-46-8 Pioglitazone 2A 108 2016
111-76-2 2-Butoxyethanol 3 88 2006
111-44-4 Bis(2-chloroethyl)ether 3 9, Sup 7, 1999
71
111-42-2 Diethanolamine 2B 77, 101 2013
11056-06-7 Bleomycins 2B 26, Sup 7 1987 NB Overall evaluation
upgraded to Group 2B
with supporting
evidence from other
relevant data
110-91-8 Morpholine 3 47, 71 1999
110-86-1 Pyridine 2B 77, 119 2019
110-57-6 trans-1,4-Dichlorobutene 3 15, Sup 7, 1999
71
110-00-9 Furan 2B 63 1995
109-99-9 Tetrahydrofuran 2B 119 2019
109-70-6 1-Bromo-3-chloropropane 2B 125 2020
online
108-99-6 β-Picoline 3 122 2019
108-95-2 Phenol 3 47, 71 1999
108-94-1 Cyclohexanone 3 47, 71 1999
108-88-3 Toluene 3 47, 71 1999
108-78-1 Melamine 2B Sup 7, 73, 2019
119
108-60-1 Bis(2-chloro-1-methylethyl)ether 3 41, Sup 7, 1999
71
108-46-3 Resorcinol 3 15, Sup 7, 1999
71
108-45-2 meta-Phenylenediamine 3 16, Sup 7 1987
108-30-5 Succinic anhydride 3 15, Sup 7 1987
108-10-1 Methyl isobutyl ketone 2B 101 2013
108-05-4 Vinyl acetate 2B Sup 7, 63 1995
1072-52-2 2-(1-Aziridinyl)ethanol 3 9, Sup 7 1987
1071-83-6 Glyphosate 2A 112 2017
107-30-2 Chloromethyl methyl ether (see
Bis(chloromethyl)ether; chloromethyl methyl
ether)
107-14-2 Chloroacetonitrile 3 52, 71 1999
107-13-1 Acrylonitrile 2B 71 1999
107-06-2 1,2-Dichloroethane 2B 20, Sup 7, 1999
71
107-05-1 Allyl chloride 3 36, Sup 7, 2020
71, 125 online
107-02-8 Acrolein 2A 63 (corr. 2021
65), Sup online
7, 128
106-99-0 1,3-Butadiene 1 Sup 7, 54, 2012
71, 97,
100F
106-94-5 1-Bromopropane 2B 115 2018
 No CAS. Agente Grupo Volumen Año Información adicional
106-93-4 Ethylene dibromide 2A 15, Sup 7, 1999 NB Overall evaluation
71 upgraded to Group 2A
with supporting
evidence from other
relevant data
106-91-2 Glycidyl methacrylate 2A 125 2020
online
106-89-8 Epichlorohydrin 2A 11, Sup 7, 1999 NB Overall evaluation
71 upgraded to Group 2A
with supporting
evidence from other
relevant data
106-88-7 1,2-Epoxybutane 2B 47, 71 1999 NB Overall evaluation
upgraded to Group 2B
with supporting
evidence from other
relevant data
106-87-6 4-Vinylcyclohexene diepoxide 2B Sup 7, 60 1994
106-51-4 para-Quinone 3 15, Sup 7, 1999
71
106-50-3 para-Phenylenediamine 3 16, Sup 7 1987
106-47-8 para-Chloroaniline 2B 57 1993
106-46-7 para-Dichlorobenzene 2B Sup 7, 73 1999
10599-90-3 Chloramine 3 84 2004
10595-95-6 N-Nitrosomethylethylamine 2B 17, Sup 7 1987
105735-71-5 3,7-Dinitrofluoranthene 2B 46, 65, 2014
105
105650-23-5 PhIP (2-Amino-1-methyl-6-phenylimidazo[4,5- 2B 56 1993
b]pyridine)
10540-29-1 Tamoxifen 1 66, 100A 2012 NB There is also
conclusive evidence
that tamoxifen reduces
the risk of contralateral
breast cancer in breast
cancer patients
105-74-8 Lauroyl peroxide 3 36, Sup 7, 1999
71
105-60-2 Caprolactam 3 39, Sup 7, 1999 Moved to Group 3
71 following 2019 update
to the IARC
Monographs Preamble
105-55-5 N,N'-Diethylthiourea 3 79 2001
105-11-3 para-Benzoquinone dioxime 3 29, Sup 7, 1999
71
104-94-9 para-Anisidine 3 27, Sup 7 1987
10380-28-6 Copper 8-hydroxyquinoline 3 15, Sup 7 1987
103-90-2 Acetaminophen (see Paracetamol)
103-90-2 Paracetamol (Acetaminophen) 3 50, 73 1999
103-33-3 Azobenzene 3 8, Sup 7 1987
103-23-1 Di(2-ethylhexyl) adipate 3 Sup 7, 77 2000
103-11-7 2-Ethylhexyl acrylate 2B 60, 122 2019
103-03-7 Phenicarbazide 3 12, Sup 7 1987
102-71-6 Triethanolamine 3 77 2000
102-50-1 meta-Cresidine 3 27, Sup 7 1987
 No CAS. Agente Grupo Volumen Año Información adicional
101043-37-2 Microcystin-LR 2B 94 2010
101-90-6 Diglycidyl resorcinol ether 2B 36, Sup 7, 1999
71
101-80-4 4,4'-Diaminodiphenyl ether 2B 29, Sup 7 1987
101-77-9 4,4'-Methylenedianiline 2B 39, Sup 7 1987
101-68-8 4,4'-Methylenediphenyl diisocyanate 3 19, Sup 7, 1999
71
101-61-1 Michler’s base [4,4´-methylenebis(N,N- 2B 27, Sup 7, 2010
dimethyl)benzenamine] 99
101-25-7 Dinitrosopentamethylenetetramine 3 11, Sup 7 1987
101-21-3 Chloropropham 3 12, Sup 7 1987
101-14-4 4,4'-Methylenebis(2-chloroaniline) (MOCA) 1 Sup 7, 57, 2012 NB Overall evaluation
99, 100F upgraded to Group 1
based on mechanistic
and other relevant data
10098-97-2 Strontium-90 (see Fission products)
10048-32-5 Parasorbic acid 3 10, Sup 7 1987
10048-13-2 Sterigmatocystin 2B 10, Sup 7 1987
10043-92-2 Radon-222 and its decay products 1 43, 78, 2012
100D
10043-66-0 Iodine-131 (see Radioiodines)
100-75-4 N-Nitrosopiperidine 2B 17, Sup 7 1987
100-42-5 Styrene 2A 60, 82, 2019
121
100-41-4 Ethylbenzene 2B 77 2000
100-40-3 4-Vinylcyclohexene 2B Sup 7, 60 1994
100-17-4 para-Nitroanisole 2B 123 2020
online
100-00-5 4-Chloronitrobenzene 2B 65, 123 2020
online
Aloe vera, whole leaf extract 2B 108 2016
Clonorchis sinensis (infection with) 1 61, 100B 2012
Fusarium graminearum, F. culmorum, and F. 3 Sup 7, 56 1993
crookwellense, toxins derived from
(zearalenone, deoxynivalenol, nivalenol, and
fusarenone X)
Fusarium sporotrichioides, toxins derived 3 56 1993
from (T-2 toxin)
Helicobacter pylori (infection with) 1 61, 100B 2012
Microcystis extracts 3 94 2010
Opisthorchis felineus (infection with) 3 61 1994
Opisthorchis viverrini (infection with) 1 61, 100B 2012
Schistosoma haematobium (infection with) 1 61, 100B 2012
Schistosoma japonicum (infection with) 2B 61 1994
Schistosoma mansoni (infection with) 3 61 1994
Acheson process, occupational exposure 1 111 2017
associated with
Acid mists, strong inorganic 1 54, 100F 2012
Acrylic fibres 3 19, Sup 7 1987
Acrylonitrile-butadiene-styrene copolymers 3 19, Sup 7 1987
Alcoholic beverages 1 44, 96, 2012
No CAS. Agente Grupo Volumen Año Información adicional
100E
Alpha particles (see Radionuclides)
Aluminium production 1 34, Sup 7, 2012
92, 100F
Anaesthetics, volatile 3 11, Sup 7 1987
Androgenic (anabolic) steroids 2A Sup 7 1987
Areca nut 1 85, 100E 2012
Arecoline 2B 128 2021
online
Art glass, glass containers and pressed ware 2A 58 1993
(manufacture of)
Auramine production 1 Sup 7, 99, 2012
100F
BK polyomavirus (BKV) 2B 104 2014
Benzidine, dyes metabolized to 1 99, 100F 2012 NB Overall evaluation
upgraded to Group 1
based on mechanistic
and other relevant data
Beta particles (see Radionuclides)
Betel quid with tobacco 1 Sup 7, 85, 2012
100E
Betel quid without tobacco 1 Sup 7, 85, 2012
100E
Biomass fuel (primarily wood), indoor 2A 95 2010
emissions from household combustion of
Bisulfites 3 54 1992
Bitumens, occupational exposure to hard 2B 103 2013
bitumens and their emissions during mastic
asphalt work
Boot and shoe manufacture and repair (see 25, Sup 7 1987
Leather dust, Benzene)
Bracken fern 2B 40, Sup 7 1987
Calcium carbide production 3 92 2010
Carbon electrode manufacture 2A 92 2010
Carpentry and joinery 2B 25, Sup 7 1987
Ceramic implants 3 74 1999
Chimney sweeping (see Soot) 92 2010
Chlorinated drinking-water 3 52 1991
Chlorinated paraffins of average carbon chain 2B 48 1990
length C12 and average degree of
chlorination approximately 60%
Chlorophenols (see Polychlorophenols)
Chlorophenoxy herbicides 2B 41, Sup 7 1987
Coal dust 3 68 1997
Coal gasification 1 Sup 7, 92, 2012
100F
Coal, indoor emissions from household 1 95, 100E 2012
combustion of
Cobalt and cobalt compounds, see Soluble
cobalt(II) salts, Cobalt metal (without
tungsten carbide or other metal alloys),
Cobalt(II) oxide, Cobalt(II,III) oxide, Cobalt(II)
No CAS. Agente Grupo Volumen Año Información adicional
sulfide, and Other cobalt(II) compounds (not
including Soluble cobalt(II) salts, Cobalt(II)
oxide, Cobalt(II,III) oxide, or Cobalt(II) sulfide)
Cobalt metal without tungsten carbide, see
Cobalt metal (without tungsten carbide or
other metal alloys)
Cobalt sulfate and other soluble cobalt(II)
salts, see Soluble cobalt(II) salts
Coffee, drinking 3 51, 116 2018 NB There is "evidence
online suggesting lack of
carcinogenicity" in
humans of coffee
drinking for cancers of
the pancreas, liver,
female breast, uterine
endometrium, and
prostate. Inverse
associations with
coffee drinking have
been observed with
cancers of the liver and
uterine endometrium.
Coke production 1 Sup 7, 92, 2012
100F
Continuous glass filament (see Glass
filament)
Dental materials 3 74 1999
Diesel engine exhaust (see Engine exhaust,
diesel)
Diesel fuel, marine 2B 45 1989 NB Overall evaluation
upgraded to Group 2B
with supporting
evidence from other
relevant data
Diesel fuels, distillate (light) 3 45 1989
Dry cleaning (occupational exposures in) 2B 63 1995
Dyes metabolized to benzidine (see
Benzidine, dyes metabolized to)
Electric fields, extremely low-frequency 3 80 2002
Electric fields, static 3 80 2002
Engine exhaust, diesel 1 46, 105 2014
Engine exhaust, gasoline 2B 46, 105 2014
Epstein-Barr virus 1 70, 100B 2012
Estrogen therapy, postmenopausal 1 72, 100A 2012
Estrogen-progestogen menopausal therapy 1 72, 91, 2012
(combined) 100A
Estrogen-progestogen oral contraceptives 1 72, 91, 2012 NB There is also
(combined) 100A convincing evidence in
humans that these
agents confer a
protective effect against
cancer in the
endometrium and ovary
Firefighter (occupational exposure as a) 2B 98 2010
Fission products, including strontium-90 1 100D 2012
No CAS. Agente Grupo Volumen Año Información adicional
Flat-glass and specialty glass (manufacture 3 58 1993
of)
Fluorescent lighting 3 55 1992
Fluoro-edenite fibrous amphibole 1 111 2017
Foreign  bodies (see Ceramic implants, Dental
materials, Implanted foreign bodies, Metallic
implants, Organic polymeric materials,
Orthopaedic implants, Polymeric implants,
Silicone breast implants)
Frying, emissions from high-temperature 2A 95 2010
Fuel oils, distillate (light) 3 45 1989
Fuel oils, residual (heavy) 2B 45 1989
Furniture and cabinet making (see Wood 25, Sup 7 1987
dust)
Gamma-Radiation (see X- and Gamma-
Radiation)
Gasoline 2B 45 1989 NB Overall evaluation
upgraded to Group 2B
with supporting
evidence from other
relevant data
Gasoline engine exhaust (see Engine exhaust,
gasoline)
Glass filament, continuous 3 43, 81 2002
Goldenseal root powder 2B 108 2016
Haematite mining (underground) 1 1, Sup 7, 2012
100D
Hair colouring products (personal use of) 3 57, 99 2010
Hairdresser or barber (occupational exposure 2A 57, 99 2010
as a)
Hepatitis B virus (chronic infection with) 1 59, 100B 2012
Hepatitis C virus (chronic infection with) 1 59, 100B 2012
Hepatitis D virus 3 59 1994
Hexachlorocyclohexanes 2B 20, Sup 7 1987
High-temperature frying (see Frying)
Household combustion of biomass fuel (see
Biomass fuel, indoor emissions from
household combustion of)
Household combustion of coal (see Coal,
indoor emissions from household
combustion)
Human T-cell lymphotropic virus type I 1 67, 100B 2012
Human T-cell lymphotropic virus type II 3 67 1996
Human herpesvirus type 4 (see Epstein-Barr
virus)
Human herpesvirus type 8 (see Kaposi
sarcoma herpesvirus)
Human immunodeficiency virus type 1 1 67, 100B 2012
(infection with)
Human immunodeficiency virus type 2 2B 67 1996
(infection with)
Human papillomavirus genus beta (except 3 90, 100B 2012
types 5 and 8) and genus gamma
No CAS. Agente Grupo Volumen Año Información adicional
Human papillomavirus type 68 2A 100B 2012
Human papillomavirus types 16, 18, 31, 33, 1 64, 90, 2012 NB The HPV types that
35, 39, 45, 51, 52, 56, 58, 59 100B have been classified as
carcinogenic to humans
can differ by an order of
magnitude in risk for
cervical cancer
Human papillomavirus types 26, 53, 66, 67, 2B 100B 2012
70, 73, 82
Human papillomavirus types 30, 34, 69, 85, 97 2B 100B 2012 NB Classified by
phylogenetic analogy to
the HPV genus alpha
types classified in
Group 1
Human papillomavirus types 5 and 8 (in 2B 100B 2012
patients with epidermodysplasia
verruciformis)
Human papillomavirus types 6 and 11 3 90, 100B 2012
Hypochlorite salts 3 52 1991
Implanted foreign bodies of metallic 3 74 1999
chromium or titanium and of cobalt-based,
chromium-based, and titanium-based alloys,
stainless steel and depleted uranium
Implanted foreign bodies of metallic cobalt, 2B 74 1999
metallic nickel and an alloy powder
containing 66-67% nickel, 13-16% chromium,
and 7% iron
Insulation glass wool 3 43, 81 2002
Involuntary smoking (see Tobacco smoke,
second-hand)
Ionizing radiation (all types) 1 100D 2012
Iron and steel founding (occupational 1 34, Sup 7, 2012
exposure during) 100F
Isopropyl alcohol manufacture using strong 1 Sup 7, 2012
acids 100F
Isopropyl oils 3 15, Sup 7, 1999
71
JC polyomavirus (JCV) 2B 104 2014
Jet fuel 3 45 1989
Kaposi sarcoma herpesvirus 1 70, 100B 2012
Lead compounds, inorganic 2A Sup 7, 87 2006
Lead compounds, organic 3 23, Sup 7, 2006 NB Organic lead
87 compounds are
metabolized at least in
part, to ionic lead both
in humans and animals.
To the extent that ionic
lead, generated from
organic lead, is present
in the body, it will be
expected to exert the
toxicities associated
with inorganic lead
Leather dust 1 100C 2012
Leather goods manufacture 3 25, Sup 7 1987
No CAS. Agente Grupo Volumen Año Información adicional
Leather tanning and processing 3 25, Sup 7 1987
Lumber and sawmill industries (including 3 25, Sup 7 1987
logging)
MOPP and other combined chemotherapy 1 Sup 7, 2012
including alkylating agents 100A
Madder root (Rubia tinctorum) 3 82 2002
Magenta production 1 Sup 7, 57, 2012
99, 100F
Magnetic fields, extremely low-frequency 2B 80 2002
Magnetic fields, static 3 80 2002
Malaria (caused by infection with 2A 104 2014
Plasmodium falciparum in holoendemic
areas)
Mate, hot (see Very hot beverages)
Mate, not very hot (drinking) 3 51, 116 2018
online
Merkel cell polyomavirus (MCV) 2A 104 2014
Metabisulfites 3 54 1992
Metallic implants prepared as thin smooth 2B 74 1999
films
Methylmercury compounds 2B 58 1993 NB Evaluated as a
group
Mineral oils, highly-refined 3 33, Sup 7 1987
Mineral oils, untreated or mildly treated 1 33, Sup 7, 2012
100F
Modacrylic fibres 3 19, Sup 7 1987
Neutron radiation 1 75, 100D 2012 NB Overall evaluation
upgraded to Group 1
with supporting
evidence from other
relevant data
Nickel compounds 1 Sup 7, 49, 2012
100C
Nickel refining (see Nickel compounds) 11 1976
Night shift work 2A 98, 124 2020 NB Volume 98
online evaluated shiftwork that
involves circadian
disruption
Nitrate or nitrite (ingested) under conditions 2A 94 2010
that result in endogenous nitrosation
Non-arsenical insecticides (occupational 2A 53 1991
exposures in spraying and application of)
Oestrogen (see Estrogen)
Opium consumption 1 126 2021
online
Oral contraceptives, combined estrogen-
progestogen (see Estrogen-progestogen oral
contraceptives)
Organic polymeric materials 3 74 1999
Orthopaedic implants of complex 3 74 1999
composition and cardiac pacemakers
Other cobalt(II) compounds (not including 3 52, 86, In
Soluble cobalt(II) salts, Cobalt(II) oxide, 131 prep.
No CAS. Agente Grupo Volumen Año Información adicional
Cobalt(II,III) oxide, and Cobalt(II) sulfide)
Outdoor air pollution 1 109 2016
Outdoor air pollution, particulate matter in 1 109 2016
Paint manufacture (occupational exposure in) 3 47 1989
Painter (occupational exposure as a) 1 47, 98, 2012
100F
Particulate matter in outdoor air pollution
(see Outdoor air pollution, particulate matter
in)
Paving and roofing with coal-tar pitch (see 35, Sup 7, 2010
Coal-tar pitch) 92, 100F
Pentavalent antimony 3 131 In
prep.
Petroleum refining (occupational exposures 2A 45 1989
in)
Petroleum solvents 3 47 1989
Phenacetin, analgesic mixtures containing 1 Sup 7, 2012
100A
Pickled vegetables (traditional Asian) 2B 56 1993
Polychlorinated biphenyls, dioxin-like, with a 1 107 2016 NB Overall evaluation
Toxicity Equivalency Factor (TEF) according upgraded to Group 1
to WHO (PCBs 77, 81, 105, 114, 118, 123, 126, with strong supporting
156, 157, 167, 169, 189) evidence from other
relevant data
Polychlorinated dibenzo-para-dioxins (other 3 69 1997
than 2,3,7,8-tetrachlorodibenzo-para-dioxin)
Polychlorinated dibenzofurans (see 2,3,4,7,8- 3 69 1997
Pentachlorodibenzofuran)
Polychlorophenols and their sodium salts 2B 53, 71 1999
(mixed exposures) (see Pentachlorophenol;
2,4,6-Trichlorophenol)
Polymeric implant prepared as thin smooth 2B 74 1999
films (with the exception of poly-glycolic acid)
Printing inks 3 65 1996
Printing processes (occupational exposures 2B 65 1996
in)
Processed meat (consumption of) 1 114 2018
Proflavine salts 3 24, Sup 7 1987
Progestins 2B Sup 7 1987
Progestogen-only contraceptives 2B 72 1999
Pulp and paper manufacture 3 25, Sup 7 1987
Radiofrequency electromagnetic fields 2B 102 2013
Radioiodines, including iodine-131 1 78, 100D 2012
Radionuclides, alpha-particle-emitting, 1 78, 100D 2012 NB Specific
internally deposited radionuclides for which
there is sufficient
evidence in humans are
also listed individually
as Group 1 agents
Radionuclides, beta-particle-emitting, 1 78, 100D 2012 NB Specific
internally deposited radionuclides for which
there is sufficient
evidence in humans are
also listed individually
No CAS. Agente Grupo Volumen Año Información adicional
as Group 1 agents
Red meat (consumption of) 2A 114 2018
Refractory ceramic fibres 2B 43, 81 2002
Rock (stone) wool 3 43, 81 2002
Rubber manufacturing industry 1 28, Sup 7, 2012
100F
SV40 polyomavirus 3 104 2014
Salted fish, Chinese-style 1 56, 100E 2012
Silicone breast implants 3 74 1999
Slag wool 3 43, 81 2002
Solar radiation 1 55, 100D 2012
Soluble cobalt(II) salts 2A 52, 86, In
131 prep.
Soot (as found in occupational exposure of 1 35, Sup 7, 2012
chimney sweeps) 92, 100F
Special-purpose fibres such as E-glass and 2B 81 2002
'475' glass fibres
Sulfites 3 54 1992
Sunlamps and sunbeds (see Ultraviolet-
emitting tanning devices)
Surgical implants (see Ceramic implants,
Dental materials, Implanted foreign bodies,
Metallic implants, Organic polymeric
materials, Orthopaedic implants, Polymeric
implants, Silicone breast implants)
Tea 3 51 1991
Tetrakis(hydroxymethyl)phosphonium salts 3 48, 71 1999
Textile manufacturing industry (work in) 2B 48 1990
Tobacco smoke, second-hand 1 83, 100E 2012
Tobacco smoking 1 83, 100E 2012
Tobacco, smokeless 1 Sup 7, 89, 2012
100E
Toxins derived from certain Fusarium species
(see Fusarium)
Trivalent antimony 2A 47, 131 In
prep.
Ultraviolet radiation (wavelengths 100-400 1 55, 100D*, 2018 *Volume 100D
nm, encompassing UVA, UVB, and UVC) 118# online concluded that there is
sufficient evidence for
ocular melanoma in
welders; #Volume 118
concluded that
ultraviolet emissions
from welding are
carcinogenic to humans
(Group 1). There is
sufficient evidence in
humans for the
carcinogenicity of
ultraviolet emissions
from welding)
Ultraviolet-emitting tanning devices 1 100D 2012
Urethane (see Ethyl carbamate)
Very hot beverages at above 65 °C (drinking) 2A 116 2018
 No CAS. Agente Grupo Volumen Año Información adicional
online
Weapons-grade tungsten (with nickel and 2B 131 In
cobalt) alloy prep.
Welding fumes 1 49, 118 2018
online
Wood dust 1 62, 100C 2012
Wood smoke (see Biomass fuel, indoor
emissions from household combustion)
X- and Gamma-Radiation 1 75, 100D 2012

Last updated: 2022-04-08 16.47am (CEST)