@opachis

THINK
DELIRIUM

Improving the care

for older people
Delirium toolkit
© Healthcare Improvement Scotland 2016

The contents of this document may be copied or reproduced for use within
NHSScotland, or for educational, personal or non-commercial research purposes
only. Commercial organisations must obtain written permission from Healthcare
Improvement Scotland before copying or reproducing any part of this document.

www.healthcareimprovementscotland.org
Contents
Introduction 4

Delirium risk reduction 6

Delirium management: summary pathway 7

Identifying delirium 8

4AT single assessment tool 9

4AT guidance notes 10

TIME bundle 11

TIME bundle guidance 12

4AT combined assessment tool 13

4AT repeat assessment tool 14

Delirium learning resources 15

 Improving the care for older people
Delirium toolkit

Introduction
Delirium is a state of mental confusion. It is also known as an
‘acute confusional state’.

Illness, surgery and medications can all cause delirium. It often

starts suddenly, but usually lifts when the condition causing it
gets better. It can be frightening – not only for the person who
is unwell – but also for those around him or her.

Delirium is a serious medical emergency In collaboration with the Scottish

and statistics suggest that the prevalence Delirium Association, NHS Education
of delirium in people on medical wards for Scotland and colleagues across
in hospital is about 20–30%, while 10–50% NHSScotland, Healthcare Improvement
of people having surgery develop Scotland has developed a range of tools
delirium. People who develop delirium and resources to support improvements
may need to stay longer in hospital or in in the identification and immediate
critical care, have more hospital-acquired management of delirium. This toolkit has
complications, such as falls and pressure been produced to provide easy access to
ulcers, be more likely to need to be all of these tools and resources. The tools
admitted to long term care if they are included here have been tested by small
in hospital, and are more likely to die1. teams in test sites across NHSScotland
Delirium is a recognised problem in older and feedback from staff has informed
people that is frequently overlooked or their development.
misdiagnosed and is very distressing
to individuals and to their families and
carers.

1
NICE clinical guideline 103 http://guidance.nice.org.uk/CG103
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Delirium toolkit

Who is at risk of delirium? How can I help someone

with delirium?
Any patient can develop delirium, but
certain factors can increase the risk. You can help someone with delirium feel
These include: calmer and more in control if you:

• stay calm.
• older people – the risk increases
with age. • talk to them in short, simple sentences.
• older people taking multiple • check that they have understood
medicines. you. Repeat things if necessary.
• people with dementia. • try not to agree with any unusual or
incorrect ideas, but tactfully disagree
• people who are dehydrated.
or change the subject. Reassure
• people with an infection. them. Remind them of what is
• severely ill people. happening and how they are doing.

• people who have had surgery, • remind them of the time and date.
especially hip surgery. • make sure they can see a clock or a
• people who are nearing the end of calendar.
their life. • try to make sure that someone they
• people with sight or hearing know well is with them. This is often
difficulties. most important during the evening,
when delirium often gets worse. If
• people who have a temperature. they are in hospital, bring in some
• older people with constipation or familiar objects from home.
urinary retention. • make sure they have their glasses
and hearing aid.
• help them to eat and drink.
• have a light on at night so that
they can see where they are if they
wake up.

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 Improving the care for older people
Delirium toolkit

Delirium risk reduction

Evidence suggests that up to 33% of incident delirium can be
prevented1. A range of strategies may help reduce the risk of
delirium in an older person. NICE has outlined the following
preventative interventions2 that may help you play your part in
reducing the risk of delirium for the people in your care.
Interventions to prevent delirium

Clinical factor Preventative intervention

Cognitive impairment or • Provide appropriate lighting and clear signage. A clock (consider
disorientation providing a 24-hour clock in critical care) and a calendar should also
be easily visible to the person at risk.
• Reorientate the person by explaining where they are, who they are,
and what your role is.
• Introduce cognitively stimulating activities (for example, reminiscence).
• Facilitate regular visits from family and friends.

Dehydration or constipation • Encourage the person to drink. Consider offering subcutaneous or

intravenous fluids if necessary.
• Seek advice if necessary when managing fluid balance in people with
comorbidities (for example, heart failure or chronic kidney disease).

Hypoxia • Assess for hypoxia and optimise oxygen saturation if necessary.

Immobility or limited • Encourage the person to:

mobility – mobilise soon after surgery
– walk (provide walking aids if needed – these should be accessible
at all times).
• Encourage all people, including those unable to walk, to carry out active
range-of-motion exercises.

Infection • Look for and treat infection.

• Avoid unnecessary catheterisation.
• Implement infection control procedures in line with ‘Infection control’
(NICE clinical guideline 2).

Multiple medications • Carry out a medication review for people taking multiple drugs, taking
into account both the type and number of medications.

Pain • Assess for pain. Look for non-verbal signs of pain, particularly in
people with communication difficulties.
• Start and review appropriate pain management in any person in whom
pain is identified or suspected.

Poor nutrition • Follow the advice given on nutrition in ‘Nutrition support in adults’
(NICE clinical guideline 32).
• If the person has dentures, ensure they fit properly.

Sensory impairment • Resolve any reversible cause of the impairment (such as impacted ear wax).
• Ensure working hearing and visual aids are available to and used by
people who need them.

Sleep disturbance • Avoid nursing or medical procedures during sleeping hours, if possible.
• Schedule medication rounds to avoid disturbing sleep.
• Reduce noise to a minimum during sleep periods*.
* See ‘Parkinson’s disease’ (NICE clinical guideline 35) for information about sleep hygiene.

1
Inouye SK, Bogardus ST, Charpentier PA et al. (1999) A multicomponent intervention to prevent delirium in hospitalised
older patients. N Engl J Med, 340, 669–76
2
NICE clinical guideline 103 http://guidance.nice.org.uk/CG103
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Delirium management: summary pathway

THINK DELIRIUM
History of acute change in mental status This pathway does
Change in cognition, behaviour, physical condition, ability to perform ADLs NOT relate to
*See comprehensive pathway for high risk groups alcohol or
substance misuse.
If this is suspected
Clinical suspicion of delirium or “local tool” positive use appropriate
local pathway.
[ e.g. 4AT or CAM ]

Act on acute, severe causes

e.g. infection/sepsis, hypoxia, hypoglycaemia, medicine intoxication This pathway is
appropriate for
adult patients
Clinical team should take informant history and assess capacity (18 years & over)
(e.g. is AWI Section 47 needed for basic care?) [ IQCODE AD8 ]

General observations,
arousal level, neurology, Use local tool(s) to record baseline cognition/arousal level
constipation (PR),
bladder and skin [ MOCA GPCOG AMT10 AMT4 AVPU ]
*see comprehensive Clinical assessment and full physical examination
pathway

Medication review Investigation Optimise management

See comprehensive pathway See comprehensive pathway of co-morbidity
See comprehensive pathway

Management
Treat all underlying causes
N.B. In up to 30% of cases no cause is found.
Even if no clear causes, uphold the diagnosis of delirium and manage as follows:

Medical & Nursing Environmental & Treatment of

Management General Measures Delirium Symptoms
• Document delirium, explain to patient & • Ensure glasses available and • Encourage frequent family visits to reassure
carer and provide information leaflet hearing aids are working & support care
• Assess and treat pain (e.g. by using the (check for ear wax) • Consider additional staff
Abbey Pain Scale or similar) • Sleep chart • Assess for psychotic symptoms and treat if
• Ensure O2 saturation > 95% (see comprehensive pathway) distressing
• Aim for regular mobilisation
•
(caution if COPD/Type 2 resp failure)
Avoid or treat constipation • +
Ensure adequate diet taken, keep
• If patient symptoms threaten their safety or the
safety of others use low dose of one medication
• Avoid catheterisation if possible daily food & fluid charts (*see comprehensive pathway)
• Use local person centred care • Reduce stress to patient (start low - go slow method) and review drug use
documentation e.g. “Getting to Know Me” (see comprehensive pathway) at least every 24 hours (*see local pathway).
• Consider if swallow is safe • Avoid bed moves & ensure • Inform next of kin of medication changes
orientation • Assess capacity (AWI Act & Mental Health Act)
• Avoid unnecessary interventions

Triggers for Referral to Liaison Psychiatry

Repeat delirium assessment • Severe agitation or distress not
The comprehensive pathway when clinically indicated until responding to standard measures
provides more detailed information. two successive daily negatives • Doubt about diagnosis
• If detention under the Mental Health Act
is being considered

Patient Improving Patient NOT Improving

• Reduce and discontinue any new anti-agitation drugs after 5-7 days or if severe delirium, refer to a geriatrician
• Repeat cognitive tool

Delirium can persist for

Ongoing Cognitive Impairment No Ongoing Cognitive Impairment weeks or months after
• Note delirium and inform patient’s GP • Inform patient’s GP of delirium and the risk the causes are treated
• Follow local cognitive impairment pathway of dementia in the future if an older patient

www.scottishdeliriumassociation.com
The SDA pathways are not exhaustive. Additional or alternative assessments, investigations, management strategies or treatments may be
necessary for individuals. Clinical judgement & decisions should be made by the appropriate responsible healthcare professional.
@scotdelirium
Version 1.02 FINAL – Sept 2014; Review by Aug 2015

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 Improving the care for older people
Delirium toolkit

Identifying delirium
The 4 ‘A’s Test or 4AT is an assessment tool Through testing of detection methods and
for delirium and cognitive impairment. initiation of the TIME bundle (see page 11),
The 4AT tool (www.the4at.com) is we have also created a combined tool
designed to be used by any health to detect, manage, and review delirium
professional at first contact with the through the repeat assessment.
patient, and at other times when delirium
is suspected. It incorporates the Months These tools are the start of a process to
Backwards test and the Abbreviated manage the medical emergency delirium.
Mental Test - 4 (AMT4), which are short The tools aim to help clinicians to follow
tests for cognitive impairment. The 4AT appropriate care pathways and help plan
is rapid to administer. As an assessment ongoing care and assessment to ensure
tool it does not provide a formal diagnosis safe, effective, person-centred delivery of
but a positive score should trigger more care for older people every time.
formal assessment.

It is important to involve families or carers in identifying delirium. You may want to

consider using the Single Question to Identify Delirium (SQID) which simply asks
relatives or carers, “Do you think [name of patient] has been more confused, sleepy or
drowsy?”

This simple question can help identify change and help keep families and carers involved.

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4AT single assessment tool

Name: Date: / /
Date of birth: Zero time: :
CHI number:

Practitioner name: Practitioner signature:

Designation:

[1] Alertness
This includes patients who may be markedly drowsy (eg. difficult to rouse and/or obviously sleepy
during assessment) or agitated/hyperactive. Observe the patient. If asleep, attempt to wake with speech
or gentle touch on shoulder. Ask the patient to state their name and address to assist rating.
Normal (fully alert, but not agitated, throughout assessment) 0

Mild sleepiness for <10 seconds after waking, then normal 0

Clearly abnormal 4

[2] AMT4
Age, date of birth, place (name of the hospital or building), current year.
No mistakes 0

1 mistake 1

2 or more mistakes/untestable 2

[3] Attention
Ask the patient: “Please tell me the months of the year in backwards order, starting at December.”
To assist initial understanding one prompt of “What is the month before December?” is permitted.
Achieves 7 months or more correctly 0

Starts but scores < 7 months / refuses to start 1

Untestable (cannot start because unwell, drowsy, inattentive) 2

[4] Acute change or fluctuating course

Evidence of significant change or fluctuation in: alertness, cognition, other mental function (eg.
paranoia, hallucinations) arising over the last 2 weeks and still evident in the last 24 hours.
No 0

Yes 4

4AT Score
4 or above: possible delirium +/- cognitive impairment
1-3: possible cognitive impairment
0: delirium or severe cognitive impairment unlikely
(but delirium still possible if [4] information incomplete)

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 Improving the care for older people
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4AT guidance notes

The 4AT is an assessment tool designed for rapid and sensitive initial
assessment of cognitive impairment.

Items 1-3 are rated solely on observation Alertness: Altered level of alertness is very
of the patient at the time of assessment. likely to be delirium in general hospital
settings. If the patient shows significant
Item 4 requires information from one altered alertness during the bedside
or more sources, for example your own assessment, score 4 for this item.
knowledge of the patient, other staff
who know the patient (for example AMT4 (Abbreviated Mental Test -
ward nurses), GP letter, case notes, 4): This score can be extracted from
carers. The tester should take account items in the AMT10 if the latter is done
of communication difficulties (hearing immediately before.
impairment, dysphasia, lack of common
language) when carrying out the test and Attention: the Months Backwards test
interpreting the score. assesses attention, the main cognitive
deficit in delirium; most patients with
A score of 4 or above suggests delirium delirium will show deficits. Other types
but is not diagnostic: more detailed of cognitive impairment, for example
assessment of mental status may be dementia, can also lead to deficits on this
required to reach a diagnosis. test.

A score of 1-3 suggests cognitive Acute change or fluctuating course:

impairment and more detailed cognitive Fluctuation can occur without delirium
testing and informant history-taking are in some cases of dementia, but marked
required. fluctuation usually indicates delirium.
To help elicit any hallucinations and/
A score of 0 does not definitively exclude or paranoid thoughts ask the patient
delirium or severe cognitive impairment: questions such as, “Are you concerned
more detailed testing may be required about anything going on here?”; “Do you
depending on the clinical context. feel frightened by anything or anyone?”;
“Have you been seeing or hearing
anything unusual?”

For more information, please visit:

www.the4at.com

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Improving the care for older people
Delirium toolkit

TIME bundle

Name: Date: / /
Date of birth: Zero time: :
CHI number:

Practitioner name: Practitioner signature:

Designation:

Initiate TIME within 2 hours Assessed/ Results Abnormality

(initial and write time of completion) sent seen found
Think exclude and treat possible triggers
NEWS (think sepsis six)
Blood glucose
Medication history (identify new
T medications/change of dose/medication
recently stopped)
Pain review (Abbey Pain Scale)
Assess for urinary retention
Assess for constipation
Investigate and intervene to correct underlying causes
Assess Hydration and start fluid balance chart
Bloods (FBC, U&E, Ca, LFTs, CRP, Mg, Glucose)
I Look for symptoms/signs of infection (skin,
chest, urine, CNS) and perform appropriate
cultures/imaging depending on clinical
assessment (see sepsis six)
ECG (ACS)
Management Plan Completed
M
Initiate treatment of ALL underlying causes found above
Engage and Explore (complete within 2 hours or if family/carer not present within 24 hours)
Engage with patient/family/carer – explore if this is usual behaviour.
Ask: How would you like to be involved?
E
Explain diagnosis of delirium to patient and family/carers
(use delirium leaflet)
Document diagnosis of delirium

© Healthcare Improvement Scotland 2014 v3.0 Testing May 2014

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 Improving the care for older people
Delirium toolkit

TIME bundle guidance

Within 2 hours or if
First 2 hours family/carer not present
within 24 hours

Triggers Investigate Manage Engage

Severe illness FBC, U&Es, CRP, First and Families and

LFTs, Glucose, foremost treat carers can give
Trauma/surgery Mg, Ca, PO4 underlying you a history of
urinalysis causes change. Always
Pain Consider ABG speak to them
Manage sepsis to obtain history
Infection/sepsis Culture, urine, and baseline
sputum, wounds. Refer to delirium function.
Dehydration Consider blood management:
culture (Sepsis comprehensive Families and
Hypoxia Six), CXR pathway for friends can help
complete care reorientate.
Hypoglycaemia Always carry guidance*
out routine Always document
Medications observations DO NOT USE delirium
(EWS) including RESTRAINT diagnosis.
Alcohol and drugs AVPU and Think
withdrawal Glucose AVOID Reassure families
ANTIPSYCHOTIC and carers.
Urinary retention/ Start fluid MEDICATIONS
constipation balance – these may
worsen delirium
Think about or contribute to
hydration status the risk of falls
and immobility
(see delirium
comprehensive
pathway)*

*Delirium comprehensive pathway can be found at www.scottishdeliriumassociation.com

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4AT combined assessment tool

4AT assessment tool with delirium checklist

Name: Date: / /
Date of birth: Zero time: :
CHI number:

Practitioner name: Practitioner signature:

Designation:

[1] Alertness
This includes patients who may be markedly drowsy (eg. difficult to rouse and/or obviously sleepy during assessment) or agitated/
hyperactive. Observe the patient. If asleep, attempt to wake with speech or gentle touch on shoulder.
Ask the patient to state their name and address to assist rating.
Normal (fully alert, but not agitated, throughout assessment) 0
Mild sleepiness for <10 seconds after waking, then normal 0
Clearly abnormal 4
[2] AMT4
Age, date of birth, place (name of the hospital or building), current year
No mistakes 0
1 mistake 1
2 or more mistakes/untestable 2
[3] Attention
Ask the patient: “Please tell me the months of the year in backwards order, starting at December.”
To assist initial understanding one prompt of “What is the month before December?” is permitted.
Achieves 7 months or more correctly 0
Starts but scores < 7 months / refuses to start 1
Untestable (cannot start because unwell, drowsy, inattentive) 2
[4] Acute change or fluctuating course
Evidence of significant change or fluctuation in: alertness, cognition, other mental function (eg. paranoia, hallucinations)
arising over the last 2 weeks and still evident in the last 24 hours.
No 0
Yes 4
Total

if scored 4 or more this is possible if scored 1-3 possible cognitive impairment. If scored 0 delirium or severe cognitive
delirium +/- cognitive impairment More detailed cognitive assessment and impairment unlikely (but delirium still possible if
informant history taking are required [4] information incomplete)

Initiate TIME within 2 hours Assessed/ Results Abnormality

(initial and write time of completion) sent seen found
Think exclude and treat possible triggers
NEWS (think Sepsis Six)
Blood glucose
T Medication history (identify new medications/change of dose/medication recently stopped)
Pain review (Abbey Pain Scale)
Assess for urinary retention
Assess for constipation
Investigate and intervene to correct underlying causes
Assess hydration and start fluid balance chart
Bloods (FBC, U&E, Ca, LFTs, CRP, Mg, Glucose)
I
Look for symptoms/signs of infection (skin, chest, urine, CNS) and perform appropriate
cultures/imaging depending on clinical assessment (see Sepsis Six)
ECG (ACS)
Management Plan Completed
M
Initiate treatment of ALL underlying causes found above
Engage and Explore (complete within 2 hours or if family/carer not present within 24 hours)
Engage with patient, family and carers – explore if this is usual behaviour.
E Ask: How would you like to be involved?
Explain diagnosis of delirium to patient, family and carers (use delirium leaflet)
Document diagnosis of delirium

© Healthcare Improvement Scotland 2014 v3.1 Testing Sep 2014

Delirium 4AT+Checklist 0 3.indd 1 17/09/2014 14:03

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 Improving the care for older people
Delirium toolkit

4AT repeat assessment tool

4AT repeat assessment tool

Tester:
Date:
Time:

[1] Alertness
This includes patients who may be markedly drowsy (eg. difficult to rouse and/or obviously sleepy during assessment) or
agitated/hyperactive. Observe the patient. If asleep, attempt to wake with speech or gentle touch on shoulder.
Ask the patient to state their name and address to assist rating.
Normal (fully alert, but not agitated, throughout assessment) 0 0 0 0
Mild sleepiness for <10 seconds after waking, then normal 0 0 0 0
Clearly abnormal 4 4 4 4

[2] AMT4
Age, date of birth, place (name of the hospital or building), current year.
No mistakes 0 0 0 0
1 mistake 1 1 1 1
2 or more mistakes/untestable 2 2 2 2

[3] Attention
Ask the patient: “Please tell me the months of the year in backwards order, starting at December.”
To assist initial understanding one prompt of “What is the month before December?” is permitted.
Achieves 7 months or more correctly 0 0 0 0
Starts but scores < 7 months / refuses to start 1 1 1 1
Untestable (cannot start because unwell, drowsy, inattentive) 2 2 2 2

[4] Acute change or fluctuating course

Evidence of significant change or fluctuation in: alertness, cognition, other mental function (eg. paranoia, hallucinations)
arising over the last 2 weeks and still evident in the last 24 hours.
No 0 0 0 0
Yes 4 4 4 4

4AT Score Total

4 or above: possible delirium +/- cognitive impairment
1-3: possible cognitive impairment
0: delirium or severe cognitive impairment unlikely
(but delirium still possible if [4] information incomplete)

© Healthcare Improvement Scotland 2014 v3.1 Testing Sep 2014

Delirium 4AT+Checklist 0 3.indd 2 17/09/2014 14:03

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Improving the care for older people
Delirium toolkit

Delirium learning resources

Learnpro modules
Education videos
NHS Education for Scotland, in
collaboration with colleagues from Healthcare Improvement Scotland has
across NHSScotland, has developed a produced a series of videos to help
range of learning resources to support educate and raise awareness of delirium.
staff and enhance their knowledge and The videos include Professor Alasdair
understanding of delirium. Although MacLullich, University of Edinburgh,
the Improving Care for Older People helping to explain what delirium is,
programme focuses on acute general the focus and importance of our work,
hospital care, it is essential that all staff and how our programme is helping to
working across health and social care are improve the care of older people in acute
able to recognise delirium, seek medical care. You can view the video gallery by
advice, provide appropriate support and searching for ‘OPAC video gallery’ at
take steps to reduce the risk of delirium. www.healthcareimprovementscotland.org
To support the diversity of learning
needs across the workforce the learning Staff, patients’ and families’
resources consist of two modules, which
are accessible on Learnpro as well as an
experiences report
interactive mobile application available on
In conjunction with University of West of
iOS and android.
Scotland, we also produced a report to
• The module ‘An Introduction to provide details of a project undertaken
Delirium’ provides the baseline to explore staff, patients’ and families’
knowledge and skills required by all experiences of episodes of delirium in an
staff working in health and social care acute hospital setting.
settings including in a person’s own We were keen to explore what it felt like
home. to both give and receive care during an
• The module ‘Delirium: Prevention, episode of delirium to:
Management and Support’ has been
• enhance our learning about caring for
designed to enhance the knowledge
patients and family during an episode
and skills of all health professionals
of delirium
working across all care sectors. It
• help us to improve communication,
will enable them to feel confident of
and
their ability to identify, treat, prevent
• contribute to the development of a
and provide appropriate support
guidance document for the delirium
to people with delirium and their
bundle.
families and carers.
This is a qualitative study which highlights
The mobile application is available to all
the importance of continued engagement
staff, but is specifically aimed at health
with everyone involved during these
professionals who use or potentially could
episodes. You can find the report at
value learning using smart phone/tablet
www.healthcareimprovementscotland.org
technology.

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