Scribd Logo
Upload

Welcome to Scribd!

  • 143 views

    Interpretation: L23 - FPSC Malviya Nagar1 A-88 Shivanand Marg, Malviyanagar Jaipur

    Uploaded by

    mahima goyal
    This document contains the results of a maternal serum screening test for Mrs. Mahima Goyal, age 28. The test results indicate AFP of 72.7 ng/mL, HCG of 20860 mIU/mL, estriol of 1.31 ng/mL, and inhibin A of 209.30 pg/mL. Based on these values and gestational age, the risk for trisomy 21 is calculated. The document also provides information on the test methodology and interpretation of results.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd

    Interpretation: L23 - FPSC Malviya Nagar1 A-88 Shivanand Marg, Malviyanagar Jaipur

    Uploaded by

    mahima goyal
    143 views4 pages
    This document contains the results of a maternal serum screening test for Mrs. Mahima Goyal, age 28. The test results indicate AFP of 72.7 ng/mL, HCG of 20860 mIU/mL, estriol of 1.31 ng/mL, and inhibin A of 209.30 pg/mL. Based on these values and gestational age, the risk for trisomy 21 is calculated. The document also provides information on the test methodology and interpretation of results.

    Original Title

    280657910_5ba2a2a5-4427-4971-8a35-1a20c122002c

    Copyright

    © © All Rights Reserved

    Available Formats

    PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    This document contains the results of a maternal serum screening test for Mrs. Mahima Goyal, age 28. The test results indicate AFP of 72.7 ng/mL, HCG of 20860 mIU/mL, estriol of 1.31 ng/mL, and inhibin A of 209.30 pg/mL. Based on these values and gestational age, the risk for trisomy 21 is calculated. The document also provides information on the test methodology and interpretation of results.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    143 views4 pages

    Interpretation: L23 - FPSC Malviya Nagar1 A-88 Shivanand Marg, Malviyanagar Jaipur

    Uploaded by

    mahima goyal
    This document contains the results of a maternal serum screening test for Mrs. Mahima Goyal, age 28. The test results indicate AFP of 72.7 ng/mL, HCG of 20860 mIU/mL, estriol of 1.31 ng/mL, and inhibin A of 209.30 pg/mL. Based on these values and gestational age, the risk for trisomy 21 is calculated. The document also provides information on the test methodology and interpretation of results.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    of 4

    .

    L23 - FPSC MALVIYA NAGAR1


    A-88 SHIVANAND MARG, MALVIYANAGAR
    JAIPUR

    Name : Mrs. MAHIMA GOYAL Collected : 16/6/2021 6:16:00PM


    Received : 16/6/2021 6:33:48PM
    Lab No. : 280657910 Age: 28 Years Gender: Female Reported : 17/6/2021 7:15:00PM
    A/c Status : P Ref By : Dr. POONAM UPADHAYAYA Report Status : Final

    Test Name Results Units Bio. Ref. Interval

    MATERNAL SERUM SCREEN 4; QUADRUPLE TEST @


    (CLIA)
    AFP 72.7 ng/mL

    HCG 20860.00 mIU/mL

    ESTRIOL, FREE 1.31 ng/mL

    INHIBIN A 209.30 pg/mL

    Interpretation
    ----------------------------------------------------------------
    | WEEKS OF | AFP | HCG | ESTRIOL,FREE | INHIBIN A|
    | GESTATION| MEDIANS | MEDIANS | MEDIANS | MEDIANS |
    | | (ng/ml) | (mIU/ml) | (ng/ml) | (pg/ml) |
    |----------|-------------|-------------|--------------|----------|
    | 14 | 27.20 | 40370 | 0.37 | 208.75 |
    |----------|-------------|-------------|--------------|----------|
    | 15 | 32.01 | 32200 | 0.55 | 222.90 |
    |----------|-------------|-------------|--------------|----------|
    | 16 | 37.67 | 25690 | 0.76 | 194.20 |
    |----------|-------------|-------------|--------------|----------|
    | 17 | 44.33 | 20490 | 1.00 | 201.30 |
    |----------|-------------|-------------|--------------|----------|
    | 18 | 52.16 | 16340 | 1.25 | 196.20 |
    |----------|-------------|-------------|--------------|----------|
    | 19 | 61.38 | 13040 | 1.50 | 226.90 |
    |----------|-------------|-------------|--------------|----------|
    | 20 | 72.33 | 10400 | 1.76 | 253.70 |
    |----------|-------------|-------------|--------------|----------|
    | 21 | 85.00 | 8295 | 1.99 | 282.10 |
    |----------|-------------|-------------|--------------|----------|
    | 22 | 100.02 | 6620 | 2.30 | 292.30 |
    ----------------------------------------------------------------

    ------------------------------------------------------------
    | Abnormality | Cut off | Detection Rate | False Positve |
    |-------------|-------------|----------------|---------------|
    | Neural tube | >=2.5 MoM | 70-75% | 2-4% |
    | defects | | | |
    |-------------|-------------|----------------|---------------|
    | Trisomy 21 | 1:250 | 75-80% | 5% |
    | (Down) | | | |
    |-------------|-------------|----------------|---------------|
    | Trisomy 18 | 1:100 | 60% | 0.3% |
    ------------------------------------------------------------

    Note
    PatientReportSCSuperPanel.GENERAL_PANEL_ANALYTE_SC (Version: 6)

    *280657910*
    Page 1 of 4
    .

    L23 - FPSC MALVIYA NAGAR1


    A-88 SHIVANAND MARG, MALVIYANAGAR
    JAIPUR

    Name : Mrs. MAHIMA GOYAL Collected : 16/6/2021 6:16:00PM


    Received : 16/6/2021 6:33:48PM
    Lab No. : 280657910 Age: 28 Years Gender: Female Reported : 17/6/2021 7:15:00PM
    A/c Status : P Ref By : Dr. POONAM UPADHAYAYA Report Status : Final

    Test Name Results Units Bio. Ref. Interval


    · Statistical evaluation has been done using CE marked PRISCA 5 software.
    · Screening tests are based on statistical analysis of patient demographic and biochemical data. They
    simply indicate a high or low risk category. Confirmation of screen positives is recommended in the
    amniotic fluid.
    · The interpretive unit is MoM (Multiples of Median) which takes into account variables such as
    gestational age (ultrasound), maternal weight, race, insulin dependent Diabetes, multiple gestation, IVF
    (Date of Birth of Donor, if applicable), smoking & previous history of Down syndrome. Accurate
    availability of this data for Risk Calculation is critical.
    · Ideally all pregnant women should be screened for Prenatal disorders irrespective of maternal age. The
    test is valid between 14-22 weeks of gestation, but ideal sampling time is between 15-20 weeks
    gestation.

    Comments
    Second trimester screening for Prenatal disorders (Trisomy 21 & 18 and Open Neural Tube defects) is
    essential to identify those women at sufficient risk for a congenital anomaly in the fetus to warrant further
    evaluation and followup. These are screening procedures which cannot discriminate all affected pregnancies
    from all unaffected pregnancies. Screening cutoffs are established by using MoM values that maximize the
    detection rate and minimize false positives. Addition of Inhibin A analysis to the Triple test protocol increases
    the detection rate of Down syndrome from 65% to 75%.

    Dr Himangshu Mazumdar Dr.Kamal Modi Dr Nimmi Kansal


    MD, Biochemistry MD, Biochemistry MD, Biochemistry
    Senior Consultant - Clinical Chemistry Consultant Biochemist National Head - Clinical Chemistry &
    & Biochemical Genetics NRL - Dr Lal PathLabs Ltd Biochemical Genetics
    NRL - Dr Lal PathLabs Ltd NRL - Dr Lal PathLabs Ltd

    -------------------------------End of report --------------------------------

    PatientReportSCSuperPanel.GENERAL_PANEL_ANALYTE_SC (Version: 6)

    *280657910*
    Page 2 of 4
    .

    L23 - FPSC MALVIYA NAGAR1


    A-88 SHIVANAND MARG, MALVIYANAGAR
    JAIPUR

    Name : Mrs. MAHIMA GOYAL Collected : 16/6/2021 6:16:00PM


    Received : 16/6/2021 6:33:48PM
    Lab No. : 280657910 Age: 28 Years Gender: Female Reported : 17/6/2021 7:15:00PM
    A/c Status : P Ref By : Dr. POONAM UPADHAYAYA Report Status : Final

    Test Name Results Units Bio. Ref. Interval


    IMPORTANT INSTRUCTIONS

    *Test results released pertain to the specimen submitted .*All test results are dependent on the quality of the sample received by the Laboratory .
    *Laboratory investigations are only a tool to facilitate in arriving at a diagnosis and should be clinically correlated by the Referring Physician .*Sample
    repeats are accepted on request of Referring Physician within 7 days post reporting.*Report delivery may be delayed due to unforeseen
    circumstances. Inconvenience is regretted.*Certain tests may require further testing at additional cost for derivation of exact value. Kindly submit
    request within 72 hours post reporting.*Test results may show interlaboratory variations .*The Courts/Forum at Delhi shall have exclusive
    jurisdiction in all disputes/claims concerning the test(s) & or results of test(s).*Test results are not valid for medico legal purposes. * Contact
    customer care Tel No. +91-11-39885050 for all queries related to test results.
    (#) Sample drawn from outside source.

    PatientReportSCSuperPanel.GENERAL_PANEL_ANALYTE_SC (Version: 6)

    *280657910*
    Page 3 of 4
    .

    MATERNAL SERUM SCREEN 4 RESULTS


    Name MAHIMA GOYAL Race Asian
    Ref. By IVF no
    Lab. No. 280657910 Diabetes yes Smoking no
    Date of Birth 17/07/92 Weight 61 kg Previous Trisomy
    unknown
    Age at 21 pregancies
    Delivery 29.3 Years Twins No Sampling Date 15/06/21
    Measured Serum Values, Corrected MOM's and Risk Evaluation
    Analyte Value Units Corr. MOM's LMP Date :
    AFP 72.7 ng/mL 1.44
    Ultrasound Date : 15/06/21
    fE3 1.3 ng/mL 0.83
    Gestational Age by USG : 19 + 5
    HCG 20860.0 mIU/mL 1.32
    Inhibin-A 209.3 pg/ml 0.92 Gestational Age at sampling date : 19 + 5
    Risk
    Trisomy 21 Risk
    1:10 at term
    <1:10000

    Trisomy 18 Risk
    1:100 <1:10000
    1:250 Cut off
    Neural Tube
    Defects Risk
    1:1000 1:4986

    1:10000 Age Risk


    1:1039
    13 15 17 19 21 23 25 27 29 31 33 35 37 39 41 43 45 47 49 Age

    NEURAL TUBE DEFECTS SCREENING TRISOMY 21 SCREENING


    SCREEN NEGATIVE SCREEN NEGATIVE
    The calculated risk for spina bifida is 1:4986. There The calculated risk for Trisomy 21 is below the cut
    is no statistical indication for spina bifida. off which represents a low risk.
    Anencephaly has been excluded by ultrasound. It is expected that among more than 10000 women
    with the same data, there is one woman with a trisomy
    21 pregnancy.
    The calculated risk by PRISCA depends on the
    accuracy of the information provided by the referring
    TRISOMY 18 SCREENING physician.
    SCREEN NEGATIVE Please note that Risk calculations are statistical
    The calculated risk for trisomy 18 is <1:10000. approaches and have limited diagnostics value.
    There is no statistical indication for trisomy 18
    risk

    COMMENTS
    DR. NIMMI KANSAL
    AUTHORIZED BY
    Report Printing Date: 17. Jun 2021 PRISCA 5.2.0.13 Dr. Lal Pathlabs Pvt. Ltd.
    Page 4 of 4
    below cut off Below Cut Off, but above Age Risk above cut off

    You might also like