Laboratory Course Task 1

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LABORATORY COURSE TASK 1

Complete the table:  Enumerate 5 transfusion reactions and their causes. List the clinical signs
and nursing interventions for each transfusion reactions.  (5 pts per row)

TRANSFUSION CLINICAL SIGNS NURSING


REACTION / CAUSE INTERVENTIONS

1. Acute hemolytic reactions  Chills Stop transfusion immediately.


This can happen if  Low blood pressure Hydrate with normal saline.
there's red blood cell damage  Renal failure Maintain airway, breathing &
before the transfusion due to  Back pain circulation.
heat or an imbalance in the
cells.
2. Delayed hemolytic  Mild fever Stop transfusion immediately.
reactions  Jaundice Hydrate with normal saline.
This may happen when  Decreased post Maintain airway, breathing &
an antigen (toxin or foreign transfusion hematocrit. circulation, obtain pre-
substance) gets reintroduced transfusion bank specimens.
into your blood If ordered, replace lost blood
with additional transfusion.
3. Anaphylactic reactions  Lack of fever Stop transfusion immediately.
Similar to a simple  Urticaria Hydrate with normal saline.
allergic reaction but is more  Dyspnea Maintain airway, breathing &
severe  Chest tightness circulation, and administer
 Hypotension steroids & epinephrine as
 Decreased oxygen ordered.
saturation
4. Febrile non-hemolytic  Fever Stop transfusion immediately.
reactions  Chills Hydrate with normal saline.
This may happen when  Flushing Maintain airway, breathing &
your donor's white blood cells  Nausea most common circulation.
produce cytokines type
(substances that work with
the immune system)
5. Septic (bacteria  Fever Stop transfusion immediately.
contamination) reactions  Chills or rigors Hydrate with normal saline.
This may happen if the  Low blood pressure Maintain airway, breathing &
blood is contaminated with  Abdominal pain circulation. Give broad
bacteria or bacteria waste spectrum antibiotics as
products. ordered. Notify blood bank &
lab. Draw cultures for testing.

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