H7N9 Outbreak
H7N9 Outbreak
H7N9 Outbreak
2014
Jun; 108(4): 169–170.doi: 10.1179/2047772414Z.000000000206 about Epidemic of avian
influenza A (H7N9) virus in China, it was reported that A new avian influenza A (H7N9) has
emerged in eastern China since February 2013. Using epidemiological data from the Chinese
Center for Disease Control and Prevention, Li et al. described the laboratory-confirmed cases of
human influenza H7N9 infection in China initially identified in February through the first of
December. They reported 139 patients infected with the H7N9 virus, which peaked between
March and April. The age range of the patients was between 2 and 91 years old (median 61
years). The majority of infected individuals were male (71%) and lived in urban areas (73%).
Most had a history of recent exposure to live animals, be that in live bird markets or as poultry
workers. Probable human-to-human transmission of H7N9 was suspected in four cluster
families as some of the infected household members had no history of any exposure to animals
or live bird markets or had any direct or indirect contact with poultry.
Genetic analysis suggests that this novel H7N9 virus is triple-re-assorted. It is a low pathogenic
avian influenza (LPAI) virus found in live market poultry and wild birds. In contrast to the H5N1
virus, which was lethal in infected birds, H7N9 does not cause illness or death in infected
animals. Therefore, it is difficult to identify the source and perform surveillance in poultry thus
complication efforts to clear or destroy the source of the infection to prevent outbreaks in
humans. Comparison between H7N9 and H5N1 has been tabulated elsewhere.
as a health team in the hospital that is dealing with disaster events in this case is the H7N9
Outbreak we must be Understanding the symptoms of the disease, the mode of transmission,
and the countermeasures. Thus far, most patients with this infection have developed severe
pneumonia. Symptoms include fever, cough and shortness of breath. Information is still limited
about the full spectrum of disease that infection with influenza A(H7N9) virus might cause.
Laboratory test results provided by WHO collaborating centres for reference and research on
influenza in China and the United States suggest that the virus is susceptible to the
neuraminidase inhibitors oseltamivir and zanamivir.
It is considered likely that the new A(H7N9) viruses stem from a reassortment of three virus
strains that infect only birds. It is likely that many of the people who have been infected with
A(H7N9) virus were infected through contact with infected birds. Most of the individuals who
have been confirmed with the virus have had contact with animals or with an animal
environment, but it is not yet known how persons became infected. The possibility of animal-to-
human transmission is being investigated, as is the possibility of person-to-person transmission.