Memantine AD Drug Study

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PHINMA UNIVERSITY OF ILOILO

COLLEGE OF ALLIED HEALTH SCIENCES


Nursing Department

DRUG STUDY
Drug Name Classification/ Indications Contraindications Side effects/ Adverse Effects Nursing responsibilities
Mechanism of Action
Generic Name:  Therapeutic class:  Moderate to  Those who are  CNS: aggressiveness,  Apply the eight rights of
Memantine Anti-Alzheimer Drug severe allergic to drug and agitation, anxiety, ataxia, medication administration.
Hydrochloride  Pharmacologic Class: Alzheimer its components. confusion, depression,  Give drug without regards for
N-methyl D-aspartate dementia  Use cautiously in dizziness, fatigue, food.
receptor antagonist patients with hallucinations, headache,  Give drug the day to avoid
Brand Name:  Antagonizes N-methyl seizures, CV hypokinesia, insomnia, pain, insomnia at night and possible
Namenda D-aspartate receptors, disease, or severe somnolence, syncope, vertigo, disturbance in sleep due to
the persistent hepatic or renal TIA, drowsiness. incontinence.
activation of which impairment.  CV: HF, edema, hypertension,  Explain that drug doesn’t cure
Route: seems to increase  Use cautiously in hypotension. Alzheimer disease but may
P.O. Alzheimer symptoms. patient who may  EENT: cataracts, aid patient to maintain
have an increase conjunctivitis. function for a longer period of
urine pH.  GI: anorexia, constipation, time.
Dosage:  Use cautiously in diarrhea, nausea, vomiting,  Tell patient or caregiver to
5 mg pregnant and abdominal pain. report adverse effects.
breast-feeding  GU: incontinence, urinary  Urge patient to avoid alcohol
women. frequency, UTI. during treatment.
Frequency:  Hematologic: anemia  Advise patient not to take
O.D.
 Metabolic: weight loss or gain herbal or OTC products
 Musculoskeletal: arthralgia, without consulting prescriber.
back pain  Monitor patient carefully for
 Respiratory: bronchitis, adverse reactions as patient
coughing, dyspnea, flulike may not be able to recognize
symptoms, pneumonia, URI. changes or communicate
 Skin: rash effectively.
 Other: abnormal gait, falls,
injury, flulike symptoms

PREPARED BY: BEATRICE V. MANINGAS BSN 3

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