Abstracts: Abstracts of Papers That Were Published in The IFSCC MAGAZINE, Volume 9, No 3, 2006
Abstracts: Abstracts of Papers That Were Published in The IFSCC MAGAZINE, Volume 9, No 3, 2006
Abstracts: Abstracts of Papers That Were Published in The IFSCC MAGAZINE, Volume 9, No 3, 2006
Abstracts
Abstracts of papers that were published in the IFSCC MAGAZINE,
Volume 9, No 3, 2006
species while protecting the beneficial flora. packaged product to panellists. The given
Using a quick and reliable in vitro screening product was applied to the face twice a day
method we found several plant extracts (e.g. for 8 weeks. Instrumental measurements of
Ginseng or Black currant) which inhibit the the skin colour (a* and L* parameter), skin
inflammation-causing bacterium Propionibac- capacitance, skin tensile properties (R0, R2,
terium acnes, but do not affect beneficial spe- R6), skin thickness and skin microrelief
cies like coagulase-negative staphylococci. In parameters (Ra and Rz) were taken at base-
addition, it could also be demonstrated that a line and after 4 and 8 weeks of use. Clinical
prebiotic product line for treatment of and subjective evaluations were also carried
inflamed (or acne prone) skin showed the out at each control visit. Moreover, the
predicted effects on the microflora composi- amount of cream consumed during usage
tion in a first in vivo trial, i.e. decrease of was calculated by weighing the given jars at
Propionibacterium acnes at a constant level of each visit. Statistical analysis of the data
total bacteria. After 3 weeks, the microflora obtained showed a significant improvement
of 91% of the volunteers had been rebalanced in all instrumental parameters for both
in this way. Furthermore, these formulations groups (‘fancy’ and ‘plain’ packaging),
have been shown to exhibit excellent skin although no significant differences were
compatibility compared to an antibacterial detected between the two groups at any time.
product. Thus, prebiotic substances have the The improvement was higher in the ‘plain’
potential to provide a gentle and sustainable group for most instrumental parameters
alternative to undirected antibacterial ingre- except for micro-relief parameters where the
dients which can cause irritation, and fre- outcome was better in the ‘fancy’ group. Pro-
quently only show short time effects. motion of facial muscle relaxation deriving
Paper presented at the IFSCC Conference from the application of the fancy-packaged
2005, Florence, Italy. cream could be a possible explanation for this
finding. Also the product’s efficacy and sen-
sory properties were perceived with a higher
Objective Evaluation of the Placebo positive impact in the fancy group. The better
performance of the plain packaging group
Effect in Cosmetic Treatments.
could be related to daily application of the
A Randomized Controlled Study ‘proper’ amount of cream. In fact, this group
F. Distante, V. Pagani1, A. Bonfigli1, L. Rigano consumed a larger amount of cream than the
1
and J. Fluhr2 ‘fancy’ group. These results show that a true
1
ISPE – Institute of Skin and Product placebo effect cannot be induced by pack-
Evaluation, Via Bruschetti, 1, 20125 Milan, aging characteristics, although they can
Italy, 2Department of Dermatology, University slightly influence the degree of the expected
of Jena, 07743 Jena, Germany skin benefits in different ways. Moreover,
proper daily dosage of the product appears to
A product’s packaging and claimed efficacy be a key factor in improving the biophysical
may stimulate pleasant emotions during the skin properties related to anti-ageing and
use of cosmetics, thus enhancing their per- restoring effects.
ceived benefits. The aim of this study was to Paper presented at the IFSCC Conference
evaluate if smart packaging and strongly 2005, Florence, Italy.
claimed efficacy attributes can influence the
objectively measured efficacy, allowing a true
placebo effect to be associated with a given
cosmetic treatment. A marketed anti-aging Hydroxy Dimethoxybenzyl Malonate:
gluconolactone-based formulation was selec- A Novel Anti-(Photo)ageing Concept
ted for the study and packaged both in a T. Rudolph, P. Bühle, J. Beck, F. Pflücker,
fancy sophisticated jar and in an unbranded K.-A. Reiffen and H. Buchholz
plain container. Thirty-six female volunteers Merck KGaA, Frankfurter Strasse 250, 64293
(age range: 30–55 years) with facial photo- Darmstadt, Germany
ageing were selected for the study and ran-
domly assigned to the fancy or plain Ideally, anti-(photo)ageing concepts should
packaged product. Pre-agreed messages provide maximum efficacy, perfect stability
aimed at extolling the product’s cosmetic and cosmetic (formulation) elegance. The
effects accompanied delivery of the fancy- need for high efficacy paired with excellent