8.5 Biotechnology Applications

Biotechnology Applications - Applications
In Medicine
Biotechnology is a broad field that deals with the exploitation of living organisms to
develop products beneficial for sustainable development. It harnesses cellular and molecular
processes to develop products and technologies that could help in improving human life on
earth. It has a variety of applications that focus on human welfare. Let us have an overview
of major Biotechnology applications and its scope in today’s scenario.
Biotechnology Applications
Biotechnology is widely used in different fields such as medicine, agriculture, food
processing, etc. to produce useful products for human benefits.
The major biotechnology applications are discussed below in detail.
Biotechnology Applications in Medicine
Biotechnology has a variety of applications in the field of medicine. Some of the

biotechnology applications in medicine include the following:
Recombinant Insulin
Insulin is required by diabetic patients to remove excess sugar from the blood. Diabetic
patients have a very low level of insulin or no insulin produced by the body. Therefore, they
need external insulin to control blood glucose levels.
Later it
was discovered that the insulin produced by the pancreas of the pigs can be used by humans.
But there were not enough pigs to provide the quantities of insulin required. This led to the
cloning of the human insulin gene.
The specific gene sequence that codes for human insulin were introduced in E.coli bacteria.
The gene sequence altered the genetic composition of the E.coli cells. Within 24 hours
several E.coli bacteria containing the recombinant human insulin gene were produced. The
recombinant human insulin was isolated from E.coli cells.
Gene Therapy
Gene Therapy holds the most promising answer to the problem of genetic diseases. Gene
therapy is used to treat genetic disorders usually by the insertion of a normal gene or correct
gene for the defective or inactive gene into an individual with the help of vectors such as
retrovirus, adenovirus, and herpes simplex virus.
The normal gene replaces the defective or inactive gene and carries out its functions. The
therapy has the highest chances of developing a permanent cure if introduced in the earliest
stages of life.
Molecular Diagnosis
Medical diagnosis is another application of biotechnology in the health sector. Many times
the pathogen concentration increases by the time the disease is diagnosed. Hence, early
diagnosis and knowledge of pathophysiology are essential for an effective cure. This can be
achieved with the help of techniques such as Recombinant DNA Technology, Polymerase
Chain Reaction (PCR) and Enzyme-Linked Immunosorbent Assay (ELISA), etc.
Pharmacogenomics
Pharmacogenomics has led to the production of drugs that are best suited to an individual’s
genetic makeup. It can be applied in diseases such as cancer, depression, HIV, asthma, etc.
Edible Vaccines
Vaccines are obtained by animals and cell cultures. These vaccines contain inactivated
pathogens.
The transgenic plants can produce antigens that can be used as edible vaccines. Antigenic
proteins from several pathogens can be expressed in plants such as tomato and banana.
Transgenic sugarbeet can treat foot and mouth disease of animals, transgenic banana and
tomato can cure diseases such as cholera and hepatitis B.
Other Biotechnology Applications
1. Fermentation is an ancient invention of biotechnology. Alcohol and bread are being

produced since ages with the help of microorganisms such as yeast. In today’s
scenario, the cultures have been purified and genetically refined to produce high-
quality food products.
2. Crop improvement by crossing the plant breeds with desired traits is another
application of biotechnology in the agriculture sector.
3. Transgenic plants are genetically engineered to produce plants with desired
characteristics.
4. Tissue culture is another application of biotechnology to produce a large number of
plants with an explant. It also helps in increasing the number of endangered plant
species.
5. It is also helpful in forensics for the identification of criminals, or in paternal
disputes.

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Biotechnology Applications - Applications

The major biotechnology applications are discussed below in detail.

Biotechnology Applications in Medicine

Biotechnology has a variety of applications in the field of medicine. Some of the

Other Biotechnology Applications

1. Fermentation is an ancient invention of biotechnology. Alcohol and bread are being

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