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    Antianginal Drugs - Classification and Mechanism

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    Ahmed YT
    Angina is a type of chest pain caused by lack of oxygen to the heart muscle. There are two main types: classical angina caused by exertion and Prinzmetal's angina which occurs at rest. Drugs used to treat angina work by different mechanisms of action, including nitrates, beta blockers, calcium channel blockers, potassium channel openers, and others. Potassium channel openers like nicorandil are used not only for angina but also for hypertension, heart failure, myocardial infarction, and other conditions.

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    Antianginal Drugs - Classification and Mechanism

    Uploaded by

    Ahmed YT
    376 views1 page
    Angina is a type of chest pain caused by lack of oxygen to the heart muscle. There are two main types: classical angina caused by exertion and Prinzmetal's angina which occurs at rest. Drugs used to treat angina work by different mechanisms of action, including nitrates, beta blockers, calcium channel blockers, potassium channel openers, and others. Potassium channel openers like nicorandil are used not only for angina but also for hypertension, heart failure, myocardial infarction, and other conditions.

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    Antianginal Drugs- Classification and Mechanism

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    Angina is a type of chest pain caused by lack of oxygen to the heart muscle. There are two main types: classical angina caused by exertion and Prinzmetal's angina which occurs at rest. Drugs used to treat angina work by different mechanisms of action, including nitrates, beta blockers, calcium channel blockers, potassium channel openers, and others. Potassium channel openers like nicorandil are used not only for angina but also for hypertension, heart failure, myocardial infarction, and other conditions.

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    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    376 views1 page

    Antianginal Drugs - Classification and Mechanism

    Uploaded by

    Ahmed YT
    Angina is a type of chest pain caused by lack of oxygen to the heart muscle. There are two main types: classical angina caused by exertion and Prinzmetal's angina which occurs at rest. Drugs used to treat angina work by different mechanisms of action, including nitrates, beta blockers, calcium channel blockers, potassium channel openers, and others. Potassium channel openers like nicorandil are used not only for angina but also for hypertension, heart failure, myocardial infarction, and other conditions.

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    © All Rights Reserved
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    Antianginal Drugs

    Classification & Mechanism of Action


    Based on KD Tripathi

    Angina is a chest pain or we can say that it is a signal informing us that there is lack of oxygen supply to myocardium. This is generally occurring
    at the left side of the chest. It has 02 main types- (1) Classical Angina (Common form) - Those type of angina which may arise due to over work
    like- exercise, emotion etc. (2) Variant or prinzmetal’s Angina (uncommon form) - Attack occurs at rest or during sleep and doesn’t disappear
    after rest.

    Nitrates Beta Blocker Ca+ Channel K+ Channel Opener Others


    Propranolol, Metoprolol, Blocker Nicorandil Dipyridamole, Trimetazidine,
    Atenolol, and others Phenyl alkylamine- Ranolazine, Oxyphedrine
    Verapamil,
    Short Acting Benzothiazepine-
    Glyceryl Trinitrate Diltiazem,
    (GTN, Nitro Glycerin) Dihydropyridines-
    Nifedipin, Felodipine,
    Amlodipine, Nitrendipine,
    Nimodipine, Lacidipine,
    Long Acting Lercanidipine, Benidipine
    Isosorbide dinitrate, Isosorbide
    mononitrate, Erythrityl tetranitrate
    Pentaerythritol tetranitrate

    Other Clinical
    Application of K+ Channel Opener
    1. Angina Pectoris
    2. Hypertension
    3. Congestive heart failure
    4. Myocardial salvage in MI
    5. Alopecia
    6. Bronchial asthma
    7. Urinary urge incontinence
    8. Premature labour (Ref- KD Tripathi)

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