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    Assignment 1

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    amrit khatri

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    © All Rights Reserved
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    Assignment 1

    Uploaded by

    amrit khatri
    13 views2 pages

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    © © All Rights Reserved

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    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    13 views2 pages

    Assignment 1

    Uploaded by

    amrit khatri

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    of 2

    Assignment 1: Roll no :87

    Summary on ‘Maternal Dietary Patterns during Pregnancy Are Associated


    with Newborn Body Composition’

    The nutritional and metabolic environment of the mother during pregnancy determines the health
    and chronic disease of the offspring. Maternal nutrition during pregnancy determines the
    relationship between the adiposity during the birth and risk of overweight and obesity later in life
    of offspring. Various studies concluded the macronutrient intake associate with newborn body
    fat however studies describing data driven maternal dietary patterns associated with newborn
    born composition is still lacking. For this research, 1410 pregnant women from outpatient
    prenatal clinics were studied at University of Colorado Hospital from 2009 to 2014. Associations
    between dietary patterns and newborn fat mass, fat-free mass, and adiposity were estimated by
    using linear regression models among 764 ethnically diverse mother-infant pairs. Two dietary
    patterns were obtained by assessing the mother’s dietary through reduced-rank regression. First
    dietary pattern was characterized by poultry, nuts, cheese, fruits and whole grains and second
    pattern by starchy vegetables, eggs, fruits and low intake of diary, dark green vegetables, whole
    grain and soy. Average daily intake of total energy(kilocalories) by mother was regressed and
    residuals in subsequent analyses to examine the effects of dietary composition independent of
    total energy intake. Within 3 days of birth newborn body composition was measured by using air
    displacement plethysmography. From the study, 1 st dietary pattern was associated with greater
    Gestation Weight Gain but low maternal glucose and no differences in newborn adiposity.
    However, in 2nd dietary pattern greater maternal fasting glucose and greater newborn birth weight
    and adiposity was associated. Tertiles of each of the two dietary patterns differed the
    characteristics of the mother and infants. Women in the highest tertile of adherence to first
    dietary pattern had a lower average BMI compared with women in the lowest tertile of adherence
    which was contrasting. In the cohort, it was also found that, increased adiposity at birth is a
    strong predictor of increased adiposity at 5 months, independent of maternal and perinatal
    variables as well as infant feeding characteristics.

    From the study, it is concluded that patterns of the maternal diet during pregnancy is an
    important determinant of newborn body composition in spite of maternal obesity, total energy
    intake and physical activity. Greater maternal glucose and greater newborn adiposity is observed
    in women who adhered to a dietary pattern characterized by the intake of eggs, potatoes and
    other starchy vegetables, and non-whole grains. There may be a subtype of GWG that is
    metabolically favorable, at least with regard to maternal glucose concentrations during
    pregnancy and newborn adiposity. Greater intake of poultry, nuts and seeds, whole grains,
    cheese, and fruits by the women have greater weight gain but no other apparent adverse
    metabolic effects and no increase in newborn adiposity. These provide the evidence supporting
    the influence of maternal diet during pregnancy on the health of mother and child and also
    newborn composition.

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