TCM 09 2020 TCM Resource
TCM 09 2020 TCM Resource
TCM 09 2020 TCM Resource
Chinese Medicine
Sibao Chen
Nov. 4, 2020
Traditional Chinese Medicine (TCM)
Formula
Chinese
Patent Medicine
(CPM)
Chinese Material
Chinese Herbal Medica Decoction
medicine (CMM,中藥材)
Mineral-derived
CMM
Numbers of CMM
"Guan" medicines 關藥
"Bei" medicines 北藥
"Huai" medicines 懷藥
"Zhe" medicines 浙藥
" Jiannan" medicines 江南藥
" Chuan" medicines 川藥
" Yungui" medicines 雲貴藥
" Guang" medicines 廣藥
" Xi" medicines 西藥
“ Zang” (Tibet) medicines 藏藥
"Guan" medicines 關藥
CMM (中藥材) Botanical origin
人參 Ginseng Radix et Rhizoma Panax ginseng
Production Regions:Zhejiang.
Functions:Invigorates blood,disperses
stasis, moves Qi, stops pain.
Therapeutic use: Apply to chest impediment
and heart pain, flank and abdomen pain,
headache, waist pain, hernia pain, sinew and
bone pain, dysmenorrhea, amenorrhea,
postpartum blood stasis and abdominal pain,
江南藥: ARMM growing in provinces south of the Huai River (淮河): Hunan (湖南),
Hubei(湖北), Jiangsu(江蘇), Anhui(安徽), Fujian(福建), Jiangxi(江西)
TCM Production region Plan Origin
Notoginseng Radix
三七 Panax notoginseng
et Rhizoma
Gentiana manshurica, G.
Gentianae Radix et
龍膽 scabra, G. triflora, G.
Rhizoma
rigescens
Nardostachyos Radix et
甘松 Naradostachys jatamansi
Rhizoma
Moschus
麝香
Moschus berezovkii, Moschus sifanicus,
Moschus moschiferus
張萬福.湖北民族學院學報(醫學版),1999(02):51-55.
Lycii Fructus 枸杞子 Lycium barbarum Intraspecific differentiation of
The soil salt content of different habitats has a certain Chrynthemi Flos 菊花
effect on the polysaccharide content of Lycium barbarum
fruit. It has a long history of cultivation, and
frequent mutual introduction.
The quality of wild Salvia miltiorrhiza from Dao Di area in China and its correlation with soil
parameters and climate factors. Phytochem Anal,2020,31(4):1–8.
Chuanxiong Rhizoma
川芎
Ligusticum chuanxiong
The rhizomes of Ligusticum chuanxiong cultivated in the dam area are partly
transported to the mountain for breeding in early January.
Most of them would be cultivated in the soil until mid-May as the medicinal
material.
中國中藥雜志,2011,36(16):2303-2305.
Scutellariae Radix 黃芩: Scutellaria baicalensis
Genuine origin: Chengde Hebei (河北承德)
Main active components :flavonoids, mainly baicalin, wogonin, baicalein and wogonin,
which have antipyretic, anti-inflammatory, and antioxidant activities.
Baicalin: content of baicalin have locality feature.
Chengde Hebei > Yuncheng Shanxi > Linyi Shandong > Dingxi Gansu.
中草藥,2017,48(06):1225-1228. 生態學報,2014,34(16):4734-4745.
How to evaluate the quality of ACMM?
What’s quality and efficacy criteria of ACMM?
---Case study
Study on Quality-efficiency Evaluation of Scutellaria baicalensis from
Different Origins Based on Content Constituent Characteristics of
Flavonoids and in vitro Antiviral Activity
The anti-RSV effects of S4 from genuine origins (Hebei Chengde) and its
corresponding simulated sample E4 were the strongest.
1. Natural Factor:
Germplasm,
Genuine origin,
Medicinal parts
2.Human Factor:
collection and processing, experience identification
and quality evaluation
彭華勝,郝近大,黃璐琦.道地藥材形成要素的沿革與變遷[J].中藥材,2015,38(08):1750-1755.
Evolution and Changes of the Forming Elements of Authentic Medicinal Materials
Aurantii Fructus Immaturus
枳實
original materials
Arnebiae Radix
紫草
original materials
Change of the genuineness of medicinal
materials (藥材道地性變遷)
-- Rehmanniae Radix 地黃
《名醫別錄》 《本草經集注》 《本草圖經》 《本草綱目》
Change of Medicinal parts
---Lonicera Japonicae 金銀花
Change of Raw materials
--Asini Corii Colla 阿膠
《齊民要術》 《本草圖經》
《名醫別錄》
Reasons for the changes in the formation elements
In a strict sense, humanistic attribute of Dao-di herbs belonged to medical culture of Han
Nationality.
Distribution range of Dao-di herbs was determined by sphere of influence of central
plains dynasty.
The temperature has been decreasing, in the past 2000 years.
During this period, the temperature rose and fell several times with a cycle of centuries,
but the warm period became shorter and weaker.
彭華勝,郝近大,黃璐琦.近2000年來氣候變化對道地藥材產區變遷的影響——以澤瀉與枳殼為例[J].中國中藥雜志,2013,38(13):2218-2222.
Effect of climate change on genuine medicinal materials producing areas during last 2OOO years—Alisma orientale and Citrus aurtantium as examples
彭華勝,郝近大,黃璐琦.中國邊疆省份道地藥材分布與地緣政治格局關系[J].中國中藥雜志,2013,38(17):2901-2905.
Relationship between geopolitical political structure and distribution of Dao-di herbs in frontier provinces of China
Alismatis Rhizoma
澤瀉
Alisma orientale,
A . plantago-aquatica
Panax notoginseng was originally wild, The long-term respect and use of wild
and the genuine production region was in
Atractylodes macrocephala has
Baise, Guangxi.
gradually reduced the wild resources.
In the 1930s, P. notoginseng was The cultivation began in Zhejiang as
planted on a large scale in Wenshan,
early as the Ming Dynasty.
Yunnan.
牛加水.道地藥材的產區變化.中國民間療法,2020,28(04):91-92.
Changes in the production area of genuine medicinal materials
Fritillariae Thunbergii Bulbus
浙貝母
Fritillaria thunbergii
李華珍.浙貝母藥材道地性遷移的原因調查.中國中醫藥信息雜志,2006(08):37.
Investigation on the Reasons for the Local Migration of Fritillaria thunbergii
Dioscoreae Rhizoma
山藥
Dioscorea opposita
馮學鋒,黃璐琦,格小光,楊連菊,楊京玉.山藥道地藥材形成源流考[J].中國中藥雜志,2008(07):859-862.
Textual research on origin and development of genuine medicinal herbs of Shanyao
Aucklandiae Radix 木香
Aucklandia lappa Amomi Fructus 砂仁
Amomum villosum, A. longiligulare
Aucklandia lappa is native to India.
In 1935, Aucklandia lappa was Amomi Fructus is native to
introduced into Yunnan. Since then, Yangjiang, Guangdong.
the genuine origin is Yunnan. Amomi Fructus was introduced
into Yunnan and Hainan.
1.肖小河,金城,趙中振,肖培根,王永炎.論中藥質量控制與評價模式的創新與發展.中國中藥雜志,2007(14):1377-1381.
Probe into innovation and development of pattern of quality control and evaluation for Chinese medicine
2.謝彩香,宋經元,韓建萍,黃林芳,李西文.中藥材道地性評價與區劃研究[J].世界科學技術-中醫藥現代化,2016,18(06):950-958.
Research on Genuineness Evaluation and Regionalization of Chinese Medicinal Materials
Component Structure
張明華,封亮,胡紹英,賈曉斌.藥材道地性的物質基礎本質:組分結構的獨特性[J].中國中藥雜志,2013,38(01):136-140.
Essence of material base in geoherbs: specificality of constituent structure
Misunderstandings about ARMM(道地藥材)
1. Environmental factors are the unique factors for the formation of ARMM.
Planting
and breeding Processing
technology technology
2. ARMM are the best medicinal materials, ARMM must be better than the non-genuine.
① Genuine high-quality medicinal materials are one of the best medicinal materials.
② Although some high-quality medicinal materials are not genuine, they may be better than
genuine.
3. The more genuine the medicinal material is, the higher the content of ingredient is.
①index component≠gold standard
②The leftover material of the medicinal materials may be higher than the ingredient content of
good specification grade.
4. Genuine medicinal materials are unchanged.
Genuine and non-genuine medicinal materials are completely separable.
Genuine and non-genuine are relative and continuous, not necessarily obviously separable.
肖小河, 等.中國中藥雜志,2009,34(05):519-523.
Acknowledgement:
Pictures of TCM present in this PPT are from Chinese Medicinal Materials
Images Database published by Hong Kong Baptist University
(https://library.hkbu.edu.hk/electronic/libdbs/mmd/index.html), and Internet.
THANKS