Scribd Logo
Upload

Welcome to Scribd!

  • 268 views

    Adenomyosis Pathophysiology

    Uploaded by

    Zerfa Nishreen
    Endometriosis occurs when endometrial tissue grows outside the uterus, such as in the myometrium. Risk factors include being of reproductive age, having multiple pregnancies, and a history of uterine surgeries or trauma. The basalis endometrium invaginates into the myometrium due to increased growth factors, leading to ectopic endometrial proliferation, smooth muscle cell hyperplasia and hypertrophy, increased prostaglandins, an enlarged endometrial surface area and vascularization, and abnormal uterine contractions resulting in heavy menstrual bleeding and dysmenorrhea.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd

    Adenomyosis Pathophysiology

    Uploaded by

    Zerfa Nishreen
    268 views1 page
    Endometriosis occurs when endometrial tissue grows outside the uterus, such as in the myometrium. Risk factors include being of reproductive age, having multiple pregnancies, and a history of uterine surgeries or trauma. The basalis endometrium invaginates into the myometrium due to increased growth factors, leading to ectopic endometrial proliferation, smooth muscle cell hyperplasia and hypertrophy, increased prostaglandins, an enlarged endometrial surface area and vascularization, and abnormal uterine contractions resulting in heavy menstrual bleeding and dysmenorrhea.

    Original Title

    ADENOMYOSIS PATHOPHYSIOLOGY

    Copyright

    © © All Rights Reserved

    Available Formats

    PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Endometriosis occurs when endometrial tissue grows outside the uterus, such as in the myometrium. Risk factors include being of reproductive age, having multiple pregnancies, and a history of uterine surgeries or trauma. The basalis endometrium invaginates into the myometrium due to increased growth factors, leading to ectopic endometrial proliferation, smooth muscle cell hyperplasia and hypertrophy, increased prostaglandins, an enlarged endometrial surface area and vascularization, and abnormal uterine contractions resulting in heavy menstrual bleeding and dysmenorrhea.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    268 views1 page

    Adenomyosis Pathophysiology

    Uploaded by

    Zerfa Nishreen
    Endometriosis occurs when endometrial tissue grows outside the uterus, such as in the myometrium. Risk factors include being of reproductive age, having multiple pregnancies, and a history of uterine surgeries or trauma. The basalis endometrium invaginates into the myometrium due to increased growth factors, leading to ectopic endometrial proliferation, smooth muscle cell hyperplasia and hypertrophy, increased prostaglandins, an enlarged endometrial surface area and vascularization, and abnormal uterine contractions resulting in heavy menstrual bleeding and dysmenorrhea.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    of 1

    Downgrowth & Invagination of RISK FACTORS:

    the basalis endometrium into REPRODUCTIVE AGE,


    the myometrium MULTIPARITY, HX OF
    UTERINE SURGERIES &
    TRAUMA
    Increased expression of growth
    factors (TGF-β family) such as
    myostatin, follistatin and activin A.

    Ectopic endometrial
    proliferation

    Smooth muscle cell


    hyperplasia & hypertrophy
    Increase level of
    prostaglandin.
    Increased endometrial surface
    area, vascularization & abnormal HEAVY MENSTRUAL
    uterine contractions. BLEEDING
    DYSMENORRHEA

    You might also like