Dräger Flow Acceleration Feature v5.5.21

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Dräger Flow Acceleration Feature

Prof. Robert L. Chatburn, MHHS, RRT-NPS, FAARC ​5/5/2021

The Savina ventilator (Dräger) has a mode called Volume-Controlled Ventilation IPPV.
According to the operator’s manual, the settings for this mode include tidal volume, frequency,
inspiration time, PEEP, and flow acceleration. The manual describes flow acceleration this way:
“With the parameter »FlowAcc« the pressure and flow increase can be influenced. A greater
Flow acceleration produces a steeper pressure and flow increase. Flow acceleration (and the
inspiration time) can be used to adapt the pressure and flow curve to suit the individual patient’s
needs.” This is illustrated in Figure 1.

Figure 1. Effects of flow acceleration setting on pressure and flow waveforms.

Upon questioning the manufacturer representative (Broos, Erwin [email protected];


Senior Product Manager, Respiratory Care, Office: +49-451-882-3392, Mobile: +49-170-
8544224) I got this explanation:
“In volume controlled ventilation Savina is using FlowAcceleration as a simple straight pressure
slope with the constant steepness of the set FlowAcc (range is 5 to 200 mbar/sec). The slope
starts at PEEP level and ends if the desired VT is applied. In the simulated data (Figure 2) we
have compared ideal VC, ideal PC and FlowAcc for the same volume target.
The underlying control principle for the driving force in Savina VC-modes is pressure control.
The required pressure is generated by a turbine in combination with a valve (inspiratory valve).
The pressure is directly controlled by this valve. In the proper sense Savina is a pressure
controlled ventilator. However, in volume controlled modes the inspiratory flow is directly
measured and integrated to (display) volume. If the desired volume is reached the driving
pressure is reduced immediately. The desired VT is reached very accurately with every cycle in
contrast to PRVC (respectively Draegers Autoflow) where VT fluctuates with every breath.”

Figure 2. Simulated data (C=26ml/mbar, R=22mbar/l/s, vt=350ml, flowAcc=30mbar/s)


Dräger did not supply the equation for controlling pressure but I assume it is something like that
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derived by in the paper by Marini and Crooke (see Figure 3).

Figure 3. Clip from paper by Marini and Crooke describing constant volume ventilation by means of pressure control using a
linear model for airway pressure as a function of time. The slope of the pressure rise, a, is analogous to the Flow Acceleration
setting.

Taxonomy
We will now deduce the taxonomy of modes on the Savina ventilator with the Flow Acceleration
feature activated.
Control Variable
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The definition of volume control is that both tidal volume and flow are preset. In contrast, the
definition of pressure control is that either the inspiratory pressure target is preset of inspiratory
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pressure is proportional to the patient’s inspiratory effort. From the description above (and the
communication from the manufacturer), the Flow Acceleration feature in the mode called IPPV
is clearly a form of pressure control. This is despite the explanation in the operator’s manual that
this is a “volume control” mode. The operator sets a target tidal volume and an inspiratory time,
but not the inspiratory flow time, hence inspiratory flow is determined by pressure control
algorithm and will change as the load changes (ie, respiratory system resistance and compliance).
Furthermore, the manual states that “inspiration time (ie, inspiratory flow time) is not adjustable,
but it is the result of the compliance and resistance of the patient’s lungs together with the set
values tidal volume and flow acceleration.”
Breath Sequence
Intermittent Positive Pressure Ventilation (IPPV) is evidently a form of continuous mandatory
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ventilation, as opposed to intermittent mandatory ventilation. The manual says “The Start of the
mandatory inspiration can be synchronized with the patient’s inhalation effort with the help of
the variable flow trigger. The flow trigger can only be completely turned off in IPPV (IPPVAssist
–> IPPV).” The manual further states that “The steepness of the pressure increase from PEEP
level to the inspiration level can further be adapted with the ventilation parameter FlowAcc in
SIMV and IPPV to suit the patient’s needs.” Hence, we see that the ventilator produces both
CMV and IMV breath sequences.
Targeting Schemes
There are seven basic targeting schemes used by all ventilators. From the descriptions shown in
Table 1, we can see that only set-point targeting applies to Flow Acceleration. However, it is a
unique application in the preset target is not the peak value of the pressure waveform (ie,
inspiratory pressure) but rather the slope of the pressure waveform.
Table 1. Targeting schemes for modes of ventilation.
Mode Classifications
Because there are several features that can be activated in combination, many more modes are
available than what are listed in the table of contents of the operator’s manual.
Modes with Set-Point Targeting
From the above analysis, the modes that use Flow Acceleration on the Dräger Savina ventilator
are as follows:
• IPPV: PC-CMVs
• IPPVassist: PC-CMVs
• SIMV: PC-IMV(1)s,s
• SIMV/ASB: PC-IMV(1)s,s
But there is an added complication: this ventilator allows the addition of a Pressure Limited
Ventilation (PLV) feature. This allows the operator to set a maximum inspiratory pressure limit
(Pmax) in IPPV, IPPVAssist and SIMV and SIMV/ASB modes (Figure 4). In this case, the first
part of inspiration is pressure control with the flow assist algorithm and the last part is pressure
control with a simple static inspiratory pressure target. Thus, if PLV is activated on top of Flow
Acceleration, we would like to account for this complication, particularly because the pressure
waveform might look a lot like volume control with dual targeting. The way to do this is to
specify that there are two “varieties” of the modes above. One is simple set-point targeting using
the pressure slope and the other uses two forms of set-point targeting; (1) Flow Acceleration
alone), and (2) target slope with target inspiratory pressure together (Flow acceleration plus
Pressure Limited). This situation is similar to the way that there are three distinct varieties of PC-
CSVr: NAVA, PAV, and Tube Compensation.
Figure 4. Pressure Limited Ventilation using the Pinsp setting.

Modes with Adaptive Targeting


Another feature on the Savina ventilator is called AutoFlow. This is the name for pressure
control with adaptive targeting (ie, inspiratory pressure target is automatically adjusted to
achieve an average tidal volume, over several breaths, equal to the preset tidal volume). If
AutoFlow is activated on top of Flow Acceleration, the mode classifications change to:
• IPPV: PC-CMVsa
• IPPVassist: PC-CMVsa
• SIMV: PC-IMV(1)sa,s
• SIMV/ASB: PC-IMV(1)sa,s
This is shown in Figure 5.

Figure 5. AutoFlow activated in addition to Flow Acceleration.


References
1. ​Marini JJ, Crooke PS. A general mathematical model for respiratory dynamics relevant
to the clinical setting. Am Rev Respir Dis. 1993;147(1):14-24.
2. ​Chatburn RL, El-Khatib M, Mireles-Cabodevila E. A taxonomy for mechanical
ventilation: 10 fundamental maxims. Respir Care. 2014;59(11):1747-1763.

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