Etiologic Factors

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Etiologic Factors:

- Exposure to air pollution


- Breathing secondhand smoke Medical Management:
- Working with chemicals, dust and
fumes - Bronchodilators. Bronchodilators relieve
- A genetic condition called Alpha-1 bronchospasm by altering the smooth muscle
deficiency tone and reduce airway obstruction by
allowing increased oxygen distribution
throughout the lungs and improving alveolar
ventilation.
- Corticosteroids. A short trial course of oral
Signs and Symptoms: corticosteroids may be prescribed for patients
to determine whether pulmonary function
 Smoking depresses the activity of
improves and symptoms decrease.
scavenger cells and affects the
- Other medications. Other pharmacologic
respiratory tract’s ciliary cleansing
treatments that may be used in COPD include
mechanism.
alpha1-antitrypsin augmentation therapy,
 Occupational exposure. Prolonged antibiotic agents, mucolytic agents, antitussive
and intense exposure to agents, vasodilators, and narcotics.
occupational dust and chemicals,
indoor air pollution, and outdoor air Management of Exacerbations
pollution all contribute to the
- Optimization of bronchodilator medications is
development of COPD.
first-line therapy and involves identifying the
 Genetic abnormalities. The well-
best medications or combinations of
documented genetic risk factor is a
medications taken on a regular schedule for a
deficiency of alpha1- antitrypsin, an
specific patient.
enzyme inhibitor that protects the
- Hospitalization. Indications for hospitalization
lung parenchyma from injury.
for acute exacerbation of COPD include severe

dyspnea that does not respond to initial
therapy, confusion or lethargy, respiratory
muscle fatigue, paradoxical chest wall
movement, and peripheral edema.
Nursing Management:
- Oxygen therapy. Upon arrival of the patient in
 Assess patient’s exposure to risk the emergency room, supplemental oxygen
factors. therapy is administered and rapid assessment
 Assess the patient’s past and present is performed to determine if the exacerbation
medical history. is life-threatening.
 Assess the signs and symptoms of - Antibiotics. Antibiotics have been shown to be
COPD and their severity. of some benefit to patients with increased
 Assess the patient’s knowledge of the dyspnea, increased sputum production, and
disease. increased sputum purulence.
 Assess the patient’s vital signs.
 Assess breath sounds and pattern.

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