The Brain Regeneration Guide
The Brain Regeneration Guide
The Brain Regeneration Guide
In this document, you will learn what brain regeneration, BDNF and neuroplasticity are and
why are they important for brain health. You will understand the most common things that
can damage your brain. I will also share 12 powerful ways to heal your brain cells and support
your brain health naturally.
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What is Brain Regeneration?
Your brain is one of your most important organs. It is the center of all of your body’s functions
and systems. It serves as a command center for your nervous system that perceives stimuli,
activates responses, and obtains and sends signals across your body to keep you safe and
healthy. Your brain is also the place where your memory is stored and learning, cognition, and
individual growth is happening.
Clearly, the health of your brain is critical and should be protected. You may think that it is
normal for your brain to decline with age, however, that is not necessarily the case. Nutrition,
lifestyle habits, and other factors all affect your brain health. More importantly, and contrary
to old beliefs, your brain is able to generate new brain cells.
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How Brain Regeneration Works
Most of your brain cells are formed while you were in your mother’s womb. Other neural cells
of your brain developed during infancy. Until recent decades, doctors believed a certain level
of brain degeneration is inevitable because your brain had a limited capacity to regenerate.
Now we know better.
New research from the last two decades suggests that your brain is actually able to create
new cells throughout your lifespan and brain regeneration is possible. Your brain actually still
creates about 700 new neurons per day in the hippocampus. This allows the hippocampus to
maintain its central function.
The science of neurogenesis suggests that aerobic exercise, brain exercises, stress relief, and
other lifestyle habits can encourage brain regeneration, improve your brain health, and may
help to prevent or treat degenerative diseases, such as Alzheimer’s and Parkinson’s disease,
or reverse damage from traumatic brain injury (1, 2, 3, 4, 5, 6).
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BDNF and Synaptic Plasticity
Brain-derived neurotrophic factor or BDNF is a protein produced inside your nerve cells
to help your brain to communicate and function properly. It protects neurons, encourages
their growth, improves their functions, and helps them to survive by protecting them from
premature cell death. It also strengthens the signal between neurons by binding to the
receptors at the synapses.
BDNF is essential for optimal brain function and a key player in brain regeneration. It plays an
important role in learning and memory. It regulates various body functions, including eating
and drinking.
5
Brain Regeneration and Synaptic Density
Synapses are junctions between neurons that allow communication. Synaptic plasticity is the
change that happens at synapses and affects the quality of the communication between two
neurons. Short-term synaptic plasticity is a rapid, sub-second change that reverts to normal
quickly.
Long-term synaptic plasticity is a longer change that may last for minutes, hours, days, or
years. Long-term synaptic plasticity is critical for our brain’s ability to store information and
for our memory.
Research has shown that BDNF is critical for long-term enhancement of synaptic efficacy. It
improves neural development and synaptic plasticity, hence it may lower the risk of
neurodegenerative and psychiatric disorders, such as dementia, Alzheimer’s disease,
Huntington disease, and depression (7, 8, 9, 10, 11, 12, 13).
6
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Brain Degeneration: Causes, Symptoms & Solutions
Your brain is a powerful organ. It is the command center of your nervous system and the
center of all of your body’s functions and systems. It’s responsible for your memory, learning,
mental energy, and mood. Yet, brain degenerative disorders are rampant in our world. In the
US alone 5 million people are dealing with Alzheimer’s disease, and that’s just one form of
brain degeneration.
Brain degeneration is clearly a serious issue and its symptoms, including memory problems,
confusion, and mood changes can be quite scary. Chances are, you want to avoid these
symptoms, protect your brain, and stay mentally sharp, preserve your memory, and have a
good mood for the rest of your life. Thankfully, there are some natural strategies that can
help you with that.
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What Is Brain Degeneration?
Brain degeneration is a serious problem that our aging society is facing today.
Neurodegenerative or brain degenerative diseases cause brain and nerve deterioration
over time. They lead to memory issues, confusion, personality changes, and other symptoms
depending on the type of brain degeneration. Some brain degenerative disorders, such
as dementia, Alzheimer’s disease, and Parkinson’s disease develop and worsen overtime as
you age, while others, such as Tay-Sachs disease are genetic and develop at an earlier age.
Brain degenerative problems are on a rise. About 5 million people are affected by Alzheimer’s
disease, 1 million with Parkinson’s disease, 400,000 with multiple sclerosis (MS), 30,000
with Huntington’s disease, and 30,000 with amyotrophic lateral sclerosis (ALS) in the United
States alone (14, 15, 16)
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Major Symptoms of Brain Degeneration
Symptoms of brain degeneration may depend on the type of neurodegenerative disorder you
may be experiencing. Common symptoms include:
• Memory loss
• Forgetfulness
• Confusion
• Mood changes
• Loss of inhibition
• Anxiety
• Apathy
• Agitation
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New symptoms can develop and symptoms usually get worse over time as the condition
progresses. There is currently no cure for neurodegenerative diseases, however, early
diagnosis and treatment can be highly beneficial.
Your diet, lifestyle, and overall health all affect your brain health. Let’s take a look at the
major causes of brain degeneration.
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Blood Sugar Imbalances
When you hear the term blood sugar imbalances, you probably think about diabetes. Blood
sugar imbalances, however, not only increase your risk of diabetes but also compromise your
brain health. If your diet is high in processed carbs and refined sugar and low in vegetables,
healthy fat, and clean protein, you are setting yourself up for blood sugar imbalances.
Blood sugar imbalances may lead to memory issues, brain fog, irritability, mood fluctuations,
lightheadedness, cravings, and fatigue. Eating a high carb quick snack or meal may give you a
burst of energy, but it will also lead to a sugar drop soon after characterized by brain fog and
tiredness (19, 20).
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Environmental Toxicity
Toxins are unfortunately all around us in our polluted air, municipal tap water, non-organic
and processed foods, plastic products, moldy indoor spaces, and conventional beauty, body,
and household products. The problem is that all these environmental toxins may have a
serious impact on our brain and overall health.
Neurotoxins, such as ethanol (in alcohol), glutamate, mycotoxins, nitric oxide, botulinum toxin
(in Botox), tetrodotoxin, and tetanus toxin, are particularly damaging to your neurological
functioning. Environmental toxicity may lead to memory problems, brain fog, dementia,
neurodegenerative diseases, mood swings, irritability, fatigue, anxiety, depression, and
mental health issues (21, 22, 23).
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Sedentary Lifestyle
You may think that exercise and movement are only important for your physical strength,
toned look, or cardiovascular fitness. The truth is that they are critical for your brain health as
well.
Regular movement is especially crucial for the areas of your brain that are important
for memory formation. Leading a sedentary lifestyle may increase your risk of memory
problems, learning troubles, and cognitive decline (24, 25).
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Chronic Stress and Poor Sleep Habits
The amygdala in your brain is responsible for emotional processing. When you are under
stress, your amygdala signals your hypothalamus which is response will increase your heart
rate, heightens your senses, leads to heavier breathing and greater oxygen intake, increases
cortisol levels and rushes adrenaline across your system. The problem is that if you are
experiencing chronic stress, this stress response never ends which leads to cortisol build-up.
Cortisol is not only important for your stress response, but it also helps your hippocampus,
the part of your brain where your memories are processed and stored. When there is too
much cortisol in your system due to chronic stress, it can wear your brain down. It can impair
brain and memory function, disrupt synapse regulation, and kill brain cells. Chronic stress
has a seriously negative effect on your memory and learning and increases your risk of brain
degeneration (26, 27, 28).
If you are experiencing poor sleep on a regular basis, it may have a serious impact on your
brain and overall health. Poor sleep may increase the likelihood of chronic stress, high
cortisol, fatigue, and chronic inflammation. These factors may contribute to brain fog,
memory troubles, learning difficulties, mood swings, and low mood. Sleep deprivation
may also increase the risk of dementia, Alzheimer’s disease, and other neurodegenerative
diseases (29, 30, 31).
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Gut Infections and Dysbiosis
Again, if you think about your gut health, your brain may not be the first thing that comes to
mind. However, there is a clear and strong connection between your gut and brain health.
Just think about it. Before a speaking engagement, new date, or any other important event,
you may experience gut problems or at least butterflies in your stomach.
This connection between your gut and brain not only happens when short-term exciting or
stressful events occur, but the communication between these two organs is on-going, long-
term, and intimate. Gut dysbiosis and gut infections lead to an imbalance in your entire body
and increase chronic inflammation.
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What Is Brain Autophagy
The word autophagy comes from the Greek word ‘auto-phegein’ or ‘self-eating’. It refers
to the process of cellular recycling where the cell itself metabolizes various components in
order to reuse them and build new and healthier cell structures.
Your cells contain a number of important components called organelles. When your cells are
exposed to stressors, such as nutrient deprivation, they create a double-membrane structure
called phagophore. The phagophore is very flexible and able to surround cellular components
and deliver them to lysosomes. Lysosomes are unique organelles that are able to degrade
particular components by releasing degrading enzymes upon them. The major driver of any
autophagy is cellular stress. Your body is seeking balance and homeostasis. When stress,
such as nutrient deprivation from fasting or exercise happens, your body needs to prepare
for survival. To do this, it breaks down older or damaged cells and cellular organelles to leave
room for the creation of new and healthier ones for better energy efficiency.
Brain autophagy refers to the process of autophagy in your brain. It allows the removal of old
and damaged brain cells and the creation of new and healthy brain cells. Brain autophagy is
essential for memory, cognition, and brain health, and may help to reduce brain degeneration
(36, 37, 38, 39).
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Creating Resilient Brain Mitochondria
Did you know that there are 10,000 mitochondria per brain cell? That’s a lot
of mitochondria to take care of and keep healthy. They are the powerhouse of your brain
cells, so their healthy functioning is critical. Mitochondrial dysfunction increases the risk of
brain degeneration and brain health problems, so it is incredibly important to keep your brain
mitochondria well-functioning.
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Top 12 Brain Regeneration Strategies
Chances are, you want to say good-bye to brain fog, memory issues, learning troubles, mental
fatigue, and low mood. You certainly want to protect your brain from neurodegeneration,
dementia, and Alzheimer’s disease.
Read on to learn the top 12 ways to protect and heal your brain cells naturally. Practicing
some form of all of these strategies is important for optimizing your mental health and
keeping your brain healthy and strong.
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Anti-Inflammatory Diet
Eating an anti-inflammatory diet rich in nutrient-dense foods is critical for your brain health.
Begin by removing all inflammatory foods, including refined sugar, gluten, refined oils, deep-
fried and processed foods, conventional dairy, grain-fed meat and eggs, soda and sugary
drinks, and foods that you are sensitive to.
Instead, eat an anti-inflammatory diet with lots of greens, vegetables, low glycemic index
fruits, herbs, spices, healthy fats, grass-fed meat, and wild-caught fish. You can see the best
foods and herbs to focus on in the image below.
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Intermittent Fasting
Intermittent fasting is a fasting strategy that cycles between fasting and eating over a period
of time. It helps cellular repair, autophagy, immune regulation, inflammation levels, and
insulin sensitivity, and decreases the risk of chronic diseases, including neurodegenerative
conditions, such as Alzheimer’s (41).
Spiritual leaders and philosophers such as Plato have talked about the benefits of fasting on
improving mental efficiency, creativity, intuition and sense of well-being. If you want to learn
more about the benefits of intermittent fasting and how to practice intermittent fasting, I
recommend this article.
Extended Fasting
Extended fasting is another way to improve brain autophagy. Extended fasting goes a step
beyond intermittent fasting. While intermittent fasting only goes for anywhere between 12
to 23 hours of fasting a day, extended fasting least for at least a day, usually several hours, and
in some cases even longer.
22
Extended fasting normally involves no food for the fasting period, only calorie-free liquids,
including water and herbal tea. I only recommend extended fasting to those who are
experienced with and do well on more advanced intermittent fasting protocols.
I am not saying you have to follow a ketogenic diet all the time, you can vary your nutrition,
but actively working to get into ketosis from time to time is extremely beneficial for brain
regeneration (42, 43, 44, 45, 46, 47, 48, 49, 50, 51).
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Regular Movement and Exercise
As you’ve learned earlier, regular movement and exercise are not only part of a healthy
lifestyle, but are essential for brain health. They may help to lower chronic inflammation,
reduce stress levels, and decrease the risk of memory problems, learning troubles, and
cognitive decline.
I recommend that you exercise at least 20 to 30 minutes minimally 5 times a week. Try a
combination of cardiovascular exercise, strength and resistance training, and low-impact
exercise. Aim to stay active throughout the day by choosing to take the stairs, taking a walk at
lunch, stretching regularly, gardening, and dancing for your favorite song.
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Reduce Stress and Practice Gratitude
Reducing your stress levels is non-negotiable for brain regeneration and mental health.
To reduce your stress, try regular meditation, daily prayer, breathwork, journaling, regular
exercise, relaxation recordings, daily gratitude, and nature walks. Practice positive self-talk
and affirmations for a powerful mindset and mood shift.
Practice daily gratitude and prayer. Keep a daily gratitude journal and count your blessing
throughout the day. Remember, when you are in a state of gratitude, negative energy, stress,
and anxiety have no room.
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Prioritize Good Sleep
Prioritizing good-quality sleep is critical for your brain regeneration and mental health. It is
essential for rest, repair, and cellular rejuvenation. Develop a regular nighttime routine that
relaxes your body before sleep and works for you. Avoid sugar and caffeine throughout the
day, especially in the evening.
Turn off your electronics several hours before bedtime. Engage in relaxing activities.
Meditate, journal, reading, read, stretch, and sip on some herbal tea. Make sure that you have
a comfortable bed, bedding, and pillows. Try some black-out curtains or a sleep mask.
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Support Gut Health
As you’ve learned, your brain and gut are closely connected, hence supporting your gut is
absolutely necessary to heal your brain cells. Eating a gut-friendly, anti-inflammatory, and
nutrient-dense diet is a must.
Additionally, support a gut microbiome balance with healthy bacteria by eating probiotic-rich
foods, such as sauerkraut, kimchi, and kefir, and taking a daily probiotic supplement.
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Neurobic Exercises
Neurobics is a term used to describe the physiological effects of unique and non-routine ways
of thinking and moving and their effects on the brain to improve memory, learning, mood, and
mindset. These exercises can help stimulate brain regeneration by challenging the brain to
think and move in unique ways.
Neurobics exercises include balancing on one leg, crossword puzzles, trying a new
instrument, using your non-dominant hand, barefoot walking, and journaling. To learn more
about the benefits of neurotics exercises, I read this article (52, 53, 54, 55, 56).
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29
Reduce Your Toxic Load
To optimize your brain health, you cannot forget about reducing your toxic load. Eat organic
foods as much as possible. Remove conventional beauty, body, and household products, and
replace them with organic, natural, or homemade alternatives.
Spend time in nature as much as possible. Getting good water filtration is also especially
important. You can also get a quality Berkey filter or take it up a notch and use a hydrogen
water system which adds molecular hydrogen to combat oxidative stress and improve
immune health.
Use Magnesium
One of the key nutrients to address for proper brain regeneration is magnesium. Magnesium
is critical for brain health, mental health, relaxation, and stress relief.
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Use Autophagy Enhancing Herbs
Autophagy is your body’s natural method of detoxification. It allows your body to recycle and
get rid of old and unhealthy cells leaving room for the creation of new and healthy cells to
replace them. To heal your brain cells, I recommend autophagy-enhancing herbs, including
matcha green tea, ginger, turmeric, resveratrol, citrus bergamot, oregano, sage, rosemary,
and quercetin.
31
Use Mitochondrial Support Nutrients
For optimal brain health, I also recommend that you support your mitochondrial health. Mito
Support™ was designed to support the function of the mitochondria, which is the
powerhouse of your cell and the key cellular health.
32
Bonus: Heat Therapy
To support brain autophagy, you may want to consider heat therapy. The stress of the heat
urges your body to destroy old and damaged cells and create new and healthy cells through
the process of autophagy. Heat shock proteins (HSP) are a group of proteins that your cells
produce as a response to exposure to stressful conditions they encounter.
They play an important role in your body’s cellular repair system. They may help to stabilize
new proteins and refold damaged proteins. Saunas, UV light therapy, taking hot healing baths,
or using a heating pad on sore muscles may be forms of heat therapy (57).
For optimal immune support, brain support and other health benefits, I recommend an
infrared sauna by Synergy Science as a great affordable option with safe, deep penetrating,
detoxifying, and immune-supporting benefits.
33
Bonus: Cold Therapy
Along with heat therapy, I recommend that you consider cold therapy as well for increased
brain autophagy. In this case, the stress from the cold leads to autophagy, the removal of old
and damaged cells and the creation of new and healthy cells. Cold shock proteins or cold
shock domain (CSD) is a protein domain of about 70 amino acids.
Cold shock proteins may help your cells to survive under stressful conditions. While heat
shock proteins help your cells to survive conditions warmer than optimal, cold shock proteins
help survival in lower than optimal temperature. Cold therapy methods include cryotherapy
chambers, jumping into a cold pool, or taking a cold shower.
I recommend combining hot and cold therapy. You may want to sit in a sauna then take a cold
shower or jump into the pool. An even simpler way is finishing up your warm shower with a
cold shower (58, 59, 60, 61).
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Bonus: Red Light Therapy
Red light therapy (RLT) is a powerful therapeutic technique that may improve brain
autophagy. IT has been used for a variety of therapeutic purposes in alternative healing,
including wounds, scars, skin issues, inflammation, pain, sleep, and hair growth. It increases
cellular energy and antioxidant activity in your body. (62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72,
73).
If you are looking for a powerful, safe, effective, yet affordable red light therapy option,
I recommend Mito Red Light Therapy Device. To learn more about red light therapy, I
recommend this article.
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Bonus: Consider Hyperbaric Oxygen Therapy
For additional support, consider hyperbaric oxygen therapy. It has been shown to raise tissue
oxygen levels, encourage new blood vessel growth, increase your body’s defense system,
reduce swelling, increase stem cells, and support optimal health.
Brain regeneration can be enhanced with the use of hyperbaric oxygen therapy on a regular
basis. To learn more about hyperbaric oxygen therapy, I recommend reading this article (74,
75, 76, 77, 78).
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Final Thoughts
Brain degeneration is a serious issue that affects millions of people in the US and around the
world. The symptoms of brain degeneration memory problems, confusion, and mood changes.
To protect your brain from brain degeneration, follow my tips and try my natural solutions.
You may notice improvements not only in your cognition, mental sharpness, mood, and
energy but also in your overall health. If you want to work with a functional health coach,
I recommend this article with tips on how to find a great coach. At my clinic, we offer long-
distance and local, in-person functional health coaching programs. For further support with
your brain health recovery and other health goals, just reach out and our fantastic coaches
are here to support your journey.
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