Covid-19 Emergency Ventilator Outline

Eliciae MV20

The device described here is not yet

approved as a medical device in any
jurisdiction in the world. We offer this device
as a potential solution to help in the fight
against the global COVID-19 pandemic. The
device should only be used under supervision
of medical professionals and after
confirmation with the regulatory authorities of
your country.
Introduction to Metran

 Metran is a medical device manufacturer in Japan that specializes in High

Frequency Oscillation (HFO) ventilators mainly used in neonatal ICUs.
 Metran, together with forward-thinking clinicians, invented the HFO
ventilator and was the first company in the world to commercialize them.
 Today, our HFO ventilators are used in over 90% of NICUs in Japan and our
patented technology is in wide demand throughout the world.
 Metran also has a line of veterinary anesthesia ventilators which are market
share leaders in Japan and thousands of these devices have been safely
and effectively used for over 20 years.

The device described here is not yet approved as a medical device in any jurisdiction in the world. We offer this device
as a potential solution to help in the fight against the global COVID-19 pandemic. The device should only be used under
supervision of medical professionals and after confirmation with the regulatory authorities of your country.
 Metrans response to the COVID-19
Pandemic
 Most health experts believe that the COVID-19 pandemic will overflow the
limits of existing hospitals.
 To cope with this increased demand, governments will build make-shift
hospitals, and existing hospitals will add temporary beds, outside the ICU.
 We believe that not only will there not be enough traditional ICU ventilators
to meet this increased demand, but ventilators for these types of additional
beds have different requirements than ICU ventilators. Specifically, these
ventilators:
 Will be managed by people not familiar with ventilator management
 Must be extremely easy to use and safe under varied conditions
 Must be compact, easily managed
 Metran has a ventilator based on a series that was originally designed for
human patients, but was repurposed and marketed as the veterinary
ventilator Compos-X since 2011. We are now finalizing validation for a
modified configuration of this ventilator called Eliciae MV20 for use as an
emergency ventilator to respond to the COVID-19 pandemic.
The device described here is not yet approved as a medical device in any jurisdiction in the world. We offer this device
as a potential solution to help in the fight against the global COVID-19 pandemic. The device should only be used under
supervision of medical professionals and after confirmation with the regulatory authorities of your country.
The Eliciae MV20
 It provides time-cycled, pressure
limited ventilation (PCV)
 The user-interface is extremely easy
to use. Almost no setting changes
required between patients.
 The system design is very compact,
and rugged. Suitable for temporary
hospitals and beds.

The device described here is not yet approved as a medical device in any jurisdiction in the world. We offer this device
as a potential solution to help in the fight against the global COVID-19 pandemic. The device should only be used under
supervision of medical professionals and after confirmation with the regulatory authorities of your country.
 Clinical Factors

 We manufacture several types of ventilation equipment

including CPAPs, High-Flows, and ICU HFO vents. Even
high-specification ICU ventilators, which we
manufacture, are not appropriate for COVID from a
usability standpoint. Clinicians that will need to deal with
the overflow patients from the ICU will not be RTs or ICU
intensivists.
 These users may be ventilator novices and having them
try to manage a patient on a high-spec ICU ventilator
will be dangerous.
 Our solution is for cuffed-intubated patients with all
exhalation from the patient able to be collected by a
scavenging unit. It is not a mask or a nasal unit.
 Our solution is a pressure controlled, time-limited device
with automatic tidal volume supply. There will only be
very minimal setting adjustments needed between
patients, if at all. Just turn it on and it will work. Maybe
you just need to adjust the respiratory rate and FiO2
according to a simple protocol that will be developed
by a leading university hospital in Japan that we are
working with.

The device described here is not yet approved as a medical device in any jurisdiction in the world. We offer this device
as a potential solution to help in the fight against the global COVID-19 pandemic. The device should only be used under
supervision of medical professionals and after confirmation with the regulatory authorities of your country.
Ventilation modes

 Mandatory ventilation: A/C (assist/control) all breaths are mechanical

breaths. Ideal for muscle recovery: work of breathing is reduced, the
patient triggers the ventilator does the work at the same size of the
mechanical breaths. Tidal volume is always monitored.
 Backup ventilation: In this mode the Apnea setting controls the time
allowed without activation of breaths before the ventilator starts sending
mandatory breaths.
 Monitor: Keeps monitoring the tidal volume and pressure from a patient
with spontaneous breathing

The device described here is not yet approved as a medical device in any jurisdiction in the world. We offer this device
as a potential solution to help in the fight against the global COVID-19 pandemic. The device should only be used under
supervision of medical professionals and after confirmation with the regulatory authorities of your country.
Specifications
General
Name Eliciae MV20
Input power AC 100 to 240V (50 to 60Hz)
Operating 3 to 5 kgf/cm2
pressure

Ventilation
Ventilation Time cycle, pressure limited (PCV)
type
Mode Mandatory ventilation (A/C), Backup
Mandatory ventilation: A/C
selection ventilation, Monitor Backup ventilation: Mandatory
PIP 0 to 80cmH2O 1cmH2O resolution A/C breaths will be supplied
PEEP 0 to 20cmH2O 1cmH2O resolution when apnea is detected.
Breath rate 1 to 255 BPM 1BPM resolution
Monitor: Vt monitor capability
Inspiration 0.1 to 3.0sec 0.1sec resolution (no
time inverse ratio allowed)
Breath Flow-based, 0.1 to 10.0 Lpm sensitivity The device described here is not yet approved as a medical device in any jurisdiction in the world. We

Detection offer this device as a potential solution to help in the fight against the global COVID-19 pandemic. The
device should only be used under supervision of medical professionals and after confirmation with the
regulatory authorities of your country.
Alarms
Paw high LED alarm, audio alarm and auto alarm setting
Paw low LED alarm, audio alarm and auto alarm setting
Low gas supply LED alarm, audio alarm and auto alarm setting
Power failure LED alarm, audio alarm
Apnea LED alarm, audio alarm
Alarm mute 30 seconds

Monitoring
Tidal volume 20mL to 2,000mL ±10%+10mL
PIP 0 to 80cmH2O ±10%
PEEP 0 to 20cmH2O ±10%
Airway pressure -10cmH2O to 80cmH2O ±2cmH2O
Apnea time 1 to 60 sec. Depending on flow trigger

Others
Dimensions 260mm(W)×190mm(H)×283mm(D)
Weight 6kg The device described here is not yet approved as a medical device in any jurisdiction in the world. We offer this device
as a potential solution to help in the fight against the global COVID-19 pandemic. The device should only be used under
supervision of medical professionals and after confirmation with the regulatory authorities of your country.
 Fresh gas supply
connector
Exhaust port on the
back, which can
be attached to a
gas scavenging
system
Heat and moisture
exchanger (HME)

Fresh gas inlet

connector

22mm circuit
• This gas can be supplied by a blender if FiO2 control is required.
• This fresh gas enters the circuit near the patient-connection port, through a Jackson Rees
type connector.
• The flow rate is supplied at a higher rate than the minute-volume ventilation of the patient,
to ensure all gas going to the patient is from the fresh gas supply.
The device described here is not yet approved as a medical device in any jurisdiction in the world. We offer this device
as a potential solution to help in the fight against the global COVID-19 pandemic. The device should only be used under
supervision of medical professionals and after confirmation with the regulatory authorities of your country.
 Metran Supply

 Metran will aim to supply the following:

 Eliciae MV20 main unit
 Test lung
 Disposable patient circuits *
 Heat & Moisture Exchanger with bacterial and viral filtration *
 Key requirements for HME are (1) Resistance <1.3cm@30L/Min & <3.0cm@60L/min and
(2)
* For the items with asterisk, Metran will aim to supply a limited quantity along with deliveries of the
main unit, but it will be advisable to secure a local supply chain for replacement items.

The device described here is not yet approved as a medical device in any jurisdiction in the world. We offer this device
as a potential solution to help in the fight against the global COVID-19 pandemic. The device should only be used under
supervision of medical professionals and after confirmation with the regulatory authorities of your country.
Heat & Moisture Exchange (HME)
 Heat and Moisture Exchange with Bacterial and Viral Filtration efficiency. E
 Below is a typical specification for the HME.xample: (KEY POINT: Resistance
<1.3cm@30L/Min & <3.0cm@60L/min
 & Min Vt >200ml)

The device described here is not yet

approved as a medical device in
any jurisdiction in the world. We offer
this device as a potential solution to
Selection according to patient help in the fight against the global
COVID-19 pandemic. The device
should only be used under supervision
of medical professionals and after
confirmation with the regulatory
authorities of your country.
Blender
 To provide mixed air and oxygen to the patient with the fraction of inspired
oxygen needed (KEY POINT: Blender must have a flow controller and be
able to supply a minimum 15L/min of blended gas)

Supply of
fresh gas to
the patient.

The device described here is not yet approved as a medical device in any jurisdiction in the world. We offer this device
as a potential solution to help in the fight against the global COVID-19 pandemic. The device should only be used under
supervision of medical professionals and after confirmation with the regulatory authorities of your country.
Services / Accessories needed include

- oxygen supply (0.3~0.5MPa)

- compressed air (0.3~0.5MPa)
- treatment for the exhaust air to prevent
cross-infection from the patient’s expired
breath, e.g. scavenging system
- power supply. If using battery, power
consumption is 40VA
- final patient interface (endotracheal tube)

The device described here is not yet approved as a medical device in any jurisdiction in the world. We offer this device
as a potential solution to help in the fight against the global COVID-19 pandemic. The device should only be used under
supervision of medical professionals and after confirmation with the regulatory authorities of your country.