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    Hematologymnemonics 151002194222 Lva1 App6891

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    This document provides several mnemonics and summaries for hematology topics to aid in learning and recall: 1) Mnemonics are given for causes of macrocytic anemia, target cell identification, signs of multiple myeloma, melanoma suspicion, bone metastases primary tumors, and clotting factor names. 2) Causes of anemias, splenomegaly, vitamin B12/folate deficiencies, and differences between acute and chronic leukemias are summarized in 3 letters or less. 3) Criteria for hypersplenism, differentiating iron deficiency from chronic disease by TIBC, microcytic anemia causes, and TTP/HUS symptoms are provided

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    Hematologymnemonics 151002194222 Lva1 App6891

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    padma
    313 views8 pages
    This document provides several mnemonics and summaries for hematology topics to aid in learning and recall: 1) Mnemonics are given for causes of macrocytic anemia, target cell identification, signs of multiple myeloma, melanoma suspicion, bone metastases primary tumors, and clotting factor names. 2) Causes of anemias, splenomegaly, vitamin B12/folate deficiencies, and differences between acute and chronic leukemias are summarized in 3 letters or less. 3) Criteria for hypersplenism, differentiating iron deficiency from chronic disease by TIBC, microcytic anemia causes, and TTP/HUS symptoms are provided

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    This document provides several mnemonics and summaries for hematology topics to aid in learning and recall: 1) Mnemonics are given for causes of macrocytic anemia, target cell identification, signs of multiple myeloma, melanoma suspicion, bone metastases primary tumors, and clotting factor names. 2) Causes of anemias, splenomegaly, vitamin B12/folate deficiencies, and differences between acute and chronic leukemias are summarized in 3 letters or less. 3) Criteria for hypersplenism, differentiating iron deficiency from chronic disease by TIBC, microcytic anemia causes, and TTP/HUS symptoms are provided

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    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    313 views8 pages

    Hematologymnemonics 151002194222 Lva1 App6891

    Uploaded by

    padma
    This document provides several mnemonics and summaries for hematology topics to aid in learning and recall: 1) Mnemonics are given for causes of macrocytic anemia, target cell identification, signs of multiple myeloma, melanoma suspicion, bone metastases primary tumors, and clotting factor names. 2) Causes of anemias, splenomegaly, vitamin B12/folate deficiencies, and differences between acute and chronic leukemias are summarized in 3 letters or less. 3) Criteria for hypersplenism, differentiating iron deficiency from chronic disease by TIBC, microcytic anemia causes, and TTP/HUS symptoms are provided

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    of 8

    Hematology Mnemonics

    Macrocytic Anaemia
    Macrocytic Anaemia Leaves Big Fat Reticulocytes

    Myxoedema, Alcohol, Liver disease, B12 def., Folate def.,


    Reticulocytosis

    Target Cells
    HOT LIPS

    Haemoglobinopathy, Obs jaundice, Thallasaemia


    Liver abscess, Iron def., Polycythaemia, Sideroblastic anaemia

    Multiple Myeloma
    BAHRAIN UV

    Bone pain, Anaemia, Hyper Ca2+, Renal failure, Amyloidosis, Infection,


    Neuropathy,(hyper) Uricaemia / viscosity

    Suspect malignancy in melanoma


    BITCHES

    Bleeds, Irregular / Itch, Tender, Colour change, Halo, Enlargement,


    Satellite lesions
    Tumours which spread to bone
    PUBLIK T

    Prostate, Uterine, Breast, Lung, Intestine (stomach), Kidney, Thyroid

    Macrocytic anemia: Causes


    " ABCDEF "

     Alcohol (liver diseases)


     B12 deficiency
     Compensatory reticulocytosis (blood loss and hemolysis)
     Drug (cytotoxic drugs and AZT)/ Dysplasia (marrow disorders)
     Endocrine (hypothyroidism)
     Folate deficieny/ Fetus (pregnancy)

    Clotting factors in Blood


    " Foolish People Try Climbing Long Slopes After Christmas. Some Crazy P
    eople Have Fallen "

    Factor I = Fibrinogen
    Factor II = Prothrombin
    Factor III = Tissue factor
    Factor IV = Calcium
    Factor V = Labile factor
    Factor VI - Does not exist as it was named initially but later on
    discovered not to play a part in blood coagulation.
    Factor VII = Stable factor
    Factor VIII = Antihemophilic factor A
    Factor IX = Antihemophilic factor B or Christmas factor (named after the
    first patient in whom the factor deficiency was documented)
    Factor X = Stuart Prower factor
    Factor XI = Antihemophilic factor C
    Factor XII = Hageman factor Factor
    XIII = Fibrin stabilising factor 5
    Splenomegaly: Causes
    " CHINA "

     Congestion – portal hypertension


     Haematological – haemolytic anaemia, sickle cell disease
     Infection – Malaria, EBV, CMV, HIV
     Neoplasm – CML, myelofibrosis, lymphoma
     Autoimmune – RA, sarcoidosis, amyloidosis

    Causes of Massive splenomegaly


    " 3 M’s "
    Henoch–Schönlein purpura
    P's of HS Purpura:
    Palpable Purpura
    Pressure (Blanches on pressure)
    Pruritis
    Pain abdomen and joints
    Positive Guaiac sign in faeces
    Proteinuria
    Prednisolone given in treatment
    Platlet count may be raised but not low (DD: ITP)

    Sickle Cell Anemia


    In SICKle cell anemia (HBS), the abnormality is in the SICKsth position
    of Beta chain of HB. Valine is present instead of Glutamic acid,
    i.e. Glutamic acid Goes.
    Or remember: Sickle cell anemia is a Genetic Variation - Glutamic is
    replaced byValine

    BT, CT, PT, PTT


    Bleeding time gives Platlet response ( Remember BP )
    Clotting time gives idea about Coagulation pathway ( Remember CC )

    Also remember the following about Prothrombin Time (PT) and Partial
    Thromboplastin Time (PTT):
    PTT - Intrinsic and common pathway
    PT - Extrinsic and common pathway
    ( Remember this by imagining that Peter is going to take part in a Tea
    drinking contest. To be IN to the contest Peter must drink two Teas
    (TT) - PTT gives idea about INtrinsic and common pathway. If Peter
    drinks only one T, he is OUT = Extrinsic and common pathway
    represented by PT )

    Hodgkin's lymphoma classification

    A: Asymptomatic
    B: Bad
    Show Details / Rate It
    ---Anonymous Contributor

    Wiskott-Aldrich syndrome: symptom triad

    "PET WASP":
    Pyrogenic infections
    Eczema
    Thrombocytopenia
    · WASP is the name of the causitive agent: Wiskott-Aldrich
    Syndrome Protein.
    · Alternatively: Wiskott=Hot, Aldrich=Itch, Syndrom=Throm.
    Show Details / Rate It
    ---Robert O'Connor University College Dublin

    Sarcoidosis summarized

    SARCOIDOISIS:
    Schaumann calcifications
    Asteroid bodies/ [ACE] increase/ Anergy
    Respiratory complications/ Renal calculi/ Restrictive lung
    disease/ Restrictive cardiomyopathy
    Calcium increase in serum and urine/ CD4 helper cells
    Ocular lesions
    Immune mediated noncaseating granulomas/ [Ig] increase
    Diabetes insipidus/ [D vit.] increase/ Dyspnea
    Osteopathy
    Skin (Subcutaneous nodules, erythema nodosum)
    Interstitial lung fibrosis/ IL-1
    Seventh CN palsy
    Show Details / Rate It
    ---Rinku Uberoi UNIBE

    Apoptosis vs. necrosis

    "LIFELESS" (since cells are dead):


    · Differences are in:
    Leaky membranes
    Inflammatory response
    Fate
    Extent
    Laddering
    Energy dependent
    Swell or shrink
    Stimulus
    · See attached table for apoptosis and necrosis properties for
    each of the above.

    Show Details / Rate It


    ---Robert O'Connor University College Dublin
    Leukemias: acute vs. chronic rules of thumb

    ABCDE:
    Acute is:
    Blasts predominate
    Children
    Drastic course
    Elderly
    Few WBC's (so Fevers)
    · Chronic is all the opposites:
    Mature cells predominate
    Middle aged
    Less debilitating course
    Elevated WBC's, so not a history of fevers and infections
    Show Details / Rate It
    ---Anonymous Contributor

    Hypersplenism: criteria

    "Hyper Splenism Ravages Cells":


    Hypercellular or normal marrow
    Splenomegaly
    Response to splenectomy
    Cytopenias
    Show Details / Rate It
    ---Dr. Harsh Sharma BJMC, Pune, India

    Anemia: TIBC finding to differentiate iron deficiency vs. chronic


    disease

    TIBC levels at the:


    Top=Iron deficiency.
    Bottom=Chronic disease.
    Show Details / Rate It
    ---Robert O'Connor University College Dublin
    Microcytic anemia: causes

    "Find Those Small Cells":


    Fe deficiency
    Thalassemia
    Sideroblastic
    Chronic disease
    Show Details / Rate It
    ---K. Dang University of Toronto

    Megaloblastic anemia: vitamin B12 deficiency vs. folate


    deficiency

    Vitamin B12 deficiency also affects Brain (optic neuropathy,


    subacute combined degeneration, paresthesia).
    · Folate deficiency is not associated with neurological symptoms.
    Show Details / Rate It
    ---Glen Davis Cornell University Medical College

    Symptoms of TTP/HUS

    "Nasty Fever Ruined My Tubes":


    Neurological symptoms
    Fever
    Renal failure
    Microangiopathic hemolytic anemia
    Thrombocytopenia
    Warfarin metabolism

     Pharmacology

    ' SLOW':

     Small lipid-soluble molecule


     Liver is the site of action
     Oral route of administration.
     Warfarin

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