BC-ZEMY, A Digital Therapeutic Developed by Roche Pharma France in Partnership With Voluntis
BC-ZEMY, A Digital Therapeutic Developed by Roche Pharma France in Partnership With Voluntis
BC-ZEMY, A Digital Therapeutic Developed by Roche Pharma France in Partnership With Voluntis
health and provide new options for facilitating prevention, early diagnosis of life-threatening
diseases, and management of chronic conditions outside of traditional care settings.
From mobile medical apps and software that support the clinical decisions doctors make every day
to artificial intelligence and machine learning, digital technology has been driving a revolution in
health care. Digital health tools have the vast potential to improve our ability to accurately diagnose
and treat disease and to enhance the delivery of health care for the individual. Digital tools are
giving providers a more holistic view of patient health through access to data and giving patients
more control over their health. Digital health offers real opportunities to improve medical outcomes
and enhance efficiency.
According to Maricich, it is the only treatment authorized by the FDA for patients aged 18 years and
older experiencing addiction to and dependency on stimulants, cannabis and cocaine (as well as
alcohol).
With the digital world connecting more and more to the physical world, it was only a matter of time
that the health care sector would also be affected. Lets have an overview of the various areas where
the digital health has got its application.
1. Exercise & fitness, diet & nutrition, stress mangt, smoking cessation & alcohol moderation,
consumer wearables, Blood pressure and glucose monitors, scales, and other wearable
connected devices that send measurements directly to a computer or other database.
4. Physician may recommend app-supported disease management programs some which uses
connected biometric sensors etc.
5. Also give real time therapeutic insights of the patients to the doctors.
Digital therapeutics, a subset of digital health, is a health discipline and treatment option that utilizes
a digital and often online health technologies to treat a medical or psychological condition. Digital
therapeutics can be categorized in two ways- medication augmentation & medication replacement.
Compare getting the appointment of doctor, waiting for long hours with just simply picking up your
phone and using an app.
One also doesn’t have to explain to anyone the reason for regular visits, imp in case of mental health
where there is still some amount of stigma attached to it.
Digital apps are much more engaging, while going for office.
To date we have seen digital therapeutics being developed to address the following conditions
BC- ZEMY, a digital therapeutic developed by Roche Pharma France in partnership with Voluntis,
aims to improve care support for breast cancer patients. ZEMY promotes remote monitoring i.e
allow patients to independently manage symptoms associated with their treatment. The patient
declares symptoms, such as nausea, diarrhea, fatigue, pain, etc., via a smartphone app. In real time,
the app makes personalized recommendations to manage these symptoms. This works with a set of
clinical algorithms, and sends the data to the care team. The care team can follow the progress of
their entire patient population via a corresponding web app. To guarantee the quality of the patient
recommendations, the algorithms in ZEMY were created using the international recommendations
of recognized oncology organizations such as the American Society of Clinical Oncology (ASCO), the
European Organization for Research and Treatment of Cancer (EORTC) etc. The algorithm
parameters are defined by the healthcare professional when they prescribe ZEMY.
Propeller’s sensor and app for respiratory health management is an example of medication
augmentation. It couples its digital therapeutic with inhalers to improve the patient’s adherence to
taking their medication and produces fewer asthma or COPD episodes.
A person living with asthma or COPD attaches the Propeller sensor to their inhalers and syncs the
sensor to an app on their smartphone. The sensor gathers information each time the person uses
their inhaler. That information is transmitted to the app which tracks when the inhaler was used and
how many puffs were administered, analyzes the information, looks for patterns, and then sends the
person reminders to use their inhaler, along with suggestions about how to reduce their chances of
an asthma or COPD episode.
Propeller reports people using their digital therapeutic experience up to 79% fewer asthma attacks
and up to 50% more doses are taken on schedule.
ADHD-Biofeedback- combining digital therapeutics with sensors. With this we can measure how
stressed out the child is, by exposing them to real life situations on like a VR, a gaming console and
then also adjust the content depending on how well they are responding to what have taught to
them. Akili is pioneering the development of prescription digital treatments with direct therapeutic
activity, delivered not through a pill but through a high-quality action video game experience. Akili is
advancing a broad pipeline of programs to treat cognitive deficiency and improve symptoms
associated with medical conditions across neurology and psychiatry, including attention-
deficit/hyperactivity disorder (ADHD), major depressive disorder (MDD), autism spectrum disorder
(ASD) and various inflammatory diseases.