Scribd Logo
Upload

Welcome to Scribd!

  • 122 views

    Nimovet: Nimesulide Injection 10% W/V

    Uploaded by

    Mano Praveen
    Nimovet is an injectable nimesulide formulation used for pyrexia, musculoskeletal issues, and other inflammatory conditions in animals. It works as a COX-2 inhibitor and reduces prostaglandin synthesis and free radical formation. The recommended dosage is 3-5 mg per kg body weight in dogs and cats, and 2-4 mg per kg body weight in cattle, buffaloes, sheep, and goats by intramuscular injection every 24 hours. Possible side effects include mild gastritis in dogs at high doses and toxicity in the liver and kidneys.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd

    Nimovet: Nimesulide Injection 10% W/V

    Uploaded by

    Mano Praveen
    122 views1 page
    Nimovet is an injectable nimesulide formulation used for pyrexia, musculoskeletal issues, and other inflammatory conditions in animals. It works as a COX-2 inhibitor and reduces prostaglandin synthesis and free radical formation. The recommended dosage is 3-5 mg per kg body weight in dogs and cats, and 2-4 mg per kg body weight in cattle, buffaloes, sheep, and goats by intramuscular injection every 24 hours. Possible side effects include mild gastritis in dogs at high doses and toxicity in the liver and kidneys.

    Original Description:

    Useful vetnery medicine

    Original Title

    Nimovet

    Copyright

    © © All Rights Reserved

    Available Formats

    PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Nimovet is an injectable nimesulide formulation used for pyrexia, musculoskeletal issues, and other inflammatory conditions in animals. It works as a COX-2 inhibitor and reduces prostaglandin synthesis and free radical formation. The recommended dosage is 3-5 mg per kg body weight in dogs and cats, and 2-4 mg per kg body weight in cattle, buffaloes, sheep, and goats by intramuscular injection every 24 hours. Possible side effects include mild gastritis in dogs at high doses and toxicity in the liver and kidneys.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    122 views1 page

    Nimovet: Nimesulide Injection 10% W/V

    Uploaded by

    Mano Praveen
    Nimovet is an injectable nimesulide formulation used for pyrexia, musculoskeletal issues, and other inflammatory conditions in animals. It works as a COX-2 inhibitor and reduces prostaglandin synthesis and free radical formation. The recommended dosage is 3-5 mg per kg body weight in dogs and cats, and 2-4 mg per kg body weight in cattle, buffaloes, sheep, and goats by intramuscular injection every 24 hours. Possible side effects include mild gastritis in dogs at high doses and toxicity in the liver and kidneys.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    of 1

    BACK

    TO

    Nimovet PRODUCT
    RANGE

    Nimesulide Injection 10% w/v

    ROUTE OF ADMINISTRATION
    COMPOSITION Intra-muscular.
    Each ml contains: Nimesulide 100 mg
    DOSAGE INTERVAL
    DESCRIPTION At 24 hourly intervals.
    Nimesulide is a non-steroidal anti-inflammatory drug (NSAID) that has antipyretic
    and analgesic properties. The anti-inflammatory, analgesic and antipyretic activities INDICATIONS FOR USE
    of Nimesulide, a drug belonging to the same class of Sulfonanilide, have been Pyrexia, Musculoskeletal affections (Limping, Lameness, joint affections, sprain,
    demonstrated in a number of experimental models and in numerous clinical trials. The trauma, wounds, arthritis, Bursitis, Sinuvitis etc)
    compound is weakly acidic (pKa = 6.5) and differs from other NSAIDs as it contains in ENT affections (Rhinitis, Pharyngytis, Otitis etc)
    its chemical structure the acid group of the Sulfonanilide molecule. Nimesulide has Other Systemic or infectious diseases (Upper or lower respiratory tract infections,
    exhibited a pharmaceutical power similar to other agents, such as Indomethacin, FMD, Contagious ecthyma, mastitis etc)
    Diclofenac, Piroxicam and Ibuprofen in standard animal models of inflammation. The Post operative or surgical inflammatory conditions.
    analgesic potency of Nimesulide is similar to that of ibuprofen and indomethacin.
    Nonetheless Nimesulide has shown a higher antipyretic potency than indomethacin, CONTRA-INDICATIONS
    ibuprofen, aspirin and Paracetamol. Acute renal failures, Marked hepatic dysfunctions, blood dyscrasias, pregnancy,
    The mechanism by which Nimesulide exerts its action is complex. Nimesulide appears ulcerative gastro intestinal diseases, cardiac diseases and in neonates.
    to act at different stages of the inflammatory reaction and selectively, it is a COX-2
    inhibitor. Nimesulide has the unique feature of exhibiting multifaceted actions. NOT TO BE USED IN HORSES.
    Nimesulide inhibits Prostaglandin synthesis at the sites of inflammation. It acts as a
    competitive inhibitor of histamine and in-vitro reduces the super oxide anion formation SPECIAL PRECAUTIONS
    by activated neutrophils. Nimesulide and its active metabolite also appear to have Warfarin poisoning, Haemolytic diseases, renal and hepatic dysfunctions, severe
    direct anti-oxidant properties against various free radicals. It also inhibits the platelet cardiac diseases and in pregnancy.
    activating factor and integrin. Nimesulide may prevent the cartilage damage by inhibiting
    metalloprotienase and cytokines. POSSIBLE SIDE EFFECTS
    DOSAGE RECOMMENDATION: In dogs and cats, Nimesulide may be painful, especially in large doses, in a few cases,
    it may cause mild gastritis in dogs. Abortion may occur if administered to pregnant
    DOGS AND CATS animals.
    3-5 mg per Kg B.wt. In very high doses, Nimesulide may cause gastric irritation and toxicity symptoms in
    liver and Kidney.
    CATTLE, BUFFALOES, SHEEP AND GOATS Rarely, it causes acute renal failure in new borne and young calves, in puppies and
    2-4 mg. per Kg B.wt. Kitten.

    You might also like