Disability Certificate Guidelines
Disability Certificate Guidelines
Disability Certificate Guidelines
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[la- 16&09@2014&MhMh&III]
'kdaqrkyk MkSys xkefyu] lfpo
sd/-
(Awanish K. Awasthi)
Joint Secretary to Govt. of India
Tel.No. 24369056
To
1. All Members of the Committee
2. PS to Minister (SJ&E)
3. PS to Secretary (DEPwD)
4. PPS to JS (DEPwD)
5. PA to Director (DEPwD)
¹Hkkx IIµ[k.M 3(ii)º Hkkjr dk jkti=k % vlk/kj.k 67
Annexure II
Guidelines for the purpose of assessing the extent of specified disability in a person included under the Rights of
Persons with Disabilities Act, 2016 (49 of 2016)
I. LOCOMOTOR DISABILITY
Definition.- “Locomotor disability” means a person’s inability to execute distinctive activities associated with movement
of self and objects resulting from affliction of musculoskeletal or nervous system or both.
SECTION A:
Guidelines for Evaluation of Permanent Physical Impairment (PPI) of Extremities (Upper and Lower
Extremities)
1.1. Guidelines for Evaluation of Permanent Physical Impairment (PPI) of Upper Extremities
(a) The estimation and measurement shall be made when the clinical condition has reached the stage of maximum
improvement from the medical treatment. Normally the time period is to be decided by the medical doctor who
is evaluating the case for issuing the PPI Certificate as per standard format of the certificate.
(b) The upper extremity is divided into two component parts; the arm component and the hand component.
(c) Measurement of the loss of function of arm component consists of measuring the loss of range of motion,
muscle strength and co-ordinated activities
(d) Measurement of loss of function of hand component consists of determining the prehension, sensation and
strength. For estimation of prehension opposition, lateral pinch, cylindrical grasp, spherical grasp and hook
grasp have to be assessed.
(e) The impairment of the entire extremity depends on the combination of the impairments of both components.
(f) Total disability % will not exceed 100%.
(g) Disability is to be certified as whole number and not as a fraction.
(h) Disability is to be certified in relation to that upper extremity.
1.2.1. ARM (UPPER EXTREMITY) COMPONENT
Total value of the arm component is 90%
1.2.2. Principles of evaluation of range of motion (ROM) of joints
(a) The value of maximum ROM in the arm component is 90%
(b) Each of three joints i.e. shoulder, elbow and wrist component was earlier weighed equally - 30%. However,
functional evaluation in clinical practice indicates greater limitations imposed if hand is involved. So,
appropriate weightage is given to involvement of different joints as mentioned below;
Shoulder = up to 20%, Elbow = up to 20%, Wrist = up to 10%, & Hands = up to 40%, dependent upon extent of
involvement (mild – less than 1/3, moderate – up to 2/3, or severe – almost total). If more than one joint of the upper
extremity is involved, the loss of percentage in each joint is calculated separately as above and then added together.
1.2.3. Principles of evaluation of strength of muscles:
(a) Strength of muscles can be tested by manual method and graded from 0-5 as advocated by Medical Research
Council (MRC), London, UK depending upon the strength of the muscles (Appendix -I).
(b) Loss of muscle power can be given percentages as follows:
(i) The mean percentage of loss of muscle strength around a joint is multiplied by 0.30.
(ii) If loss of muscle strength involves more than one joint the mean loss of percentage in each joint is
calculated separately and then added together as has been described for loss of motion.
1.2.4. Principles of evaluation of coordinated activities:
(a) The total value for coordinated activities is 90%
(b) Ten different coordinated activities should be tested as given in the Form A. (Appendix II - assessment
proforma for upper extremity)
68 THE GAZETTE OF INDIA : EXTRAORDINARY [PART II—SEC. 3(ii)]
(c) Each activity has a value of 9%
(d) Average normal range of different joints for reference is at Appendix III,
1.2.5. Combining values for the Arm Component:
The total value of loss of function of arm component is obtained by combining the value of loss of ROM, muscle strength
and coordinated activities, using the combining formula.
a + b (90-a)
90
where a = higher value and b = lower value
1.3.1. HAND COMPONENT:
(a) Total value of hand component is 90%
(b) The functional impairment of hand is expressed as loss of prehension, loss of sensation and loss of strength.
1.3.2. Principles of evaluation of prehension:
Total value of prehension is 30%
It includes:
(a) Opposition - 8%
Tested against - Index finger - 2%
- Middle finger - 2%
- Ring finger - 2%
- Little finger - 2%
(b) Lateral pinch - 5% - Tested by asking the patient to hold a key between the thumb and lateral side of index
finger.
(c) Cylindrical grasp - 6% Tested for
i. Large object of approx. 4 inches size - 3%
ii. Small object of 1-2 inch size - 3%
(d) Spherical grasp - 6% Tested for
i. Large object of approx. 4 inches size - 3%
ii. Small object of 1-2 inch size - 3%
(e) Hook grasp - 5% -Tested by asking the patient to lift a bag
1.3.3. Principles of Evaluation of sensation:
(a) Total value of sensation in hand is 30%.
(b) It shall be assessed according to the distribution given below:
(i) Complete loss of sensation
Thumb ray 9%
Index finger 6%
Middle finger 5%
Ring finger 5%
Little finger 5%
(ii) Partial loss of sensation: Assessment should be made according to percentage of loss of sensation in
thumb/finger(s).
1.3.4. Principles of Evaluation of strength
(a) Total value of strength is 30%.
(b) It includes:
(i) Grip strength 20%
(ii) Pinch strength 10%
¹Hkkx IIµ[k.M 3(ii)º Hkkjr dk jkti=k % vlk/kj.k 69
Strength of hand should be tested with hand dynamo-meter or by clinical method (grip method). 10% weightage to be
given to persons with involvement of dominant upper extremity (mostly right upper extremity) due to acquired
conditions (diseases/ injuries etc.).
For shortening of upper extremity, addition weightage is as follows:
First 1" - No additional weightage
For each 1" beyond first 1" - 2% additional weightage.
Additional weightage - A total of upto 10% additional weightage can be given to following accompanying factors if they
are continuous and persistent despite treatment.
(i) Deformity
In functional position 3%
In non-functional position 6%
(ii) Pain
Severe (grossly interfering with function) 9%
Moderate (interfering with function) 6%
Mild (slightly interfering with function) 3%
(iii) Loss of sensation
Complete Loss 9%
Partial Loss 6%
(iv) Complications
Superficial complications 3%
Deep complications 6%
Total % of PPI will not exceed 100% in any case.
Disability % is to be certified in relation to that extremity.
Disability % is to be mentioned as whole number, and not as a fraction.
1.3.5. Combining values of hand component:
The final value of loss of function of hand component is obtained by summing up values of loss of prehension, sensation
and strength.
1.3.6. Combining values for the Extremity:
Values of impairment of arm component and impairment of hand component should be added by using combining
formula:
a + b (90-a)/90
where a = higher value and b = lower value.
2. Guidelines for Evaluation of Permanent Physical Impairment in Lower Extremity
The measurement of loss of function in lower extremity is divided into two components, namely, mobility and stability
components.
2.1.1. MOBILITY COMPONENT
Total value of mobility component is 90% which includes range of movement (ROM) and muscle strength.
2.1.2. Principles of Evaluation of Range of Movement:
(a) The value of maximum range of movement in mobility component is 90%
(b) Each of three joints i.e. hip, knee and foot-ankle component was earlier weighed equally - 30%, but functional
evaluation in clinical practice indicates greater limitations imposed if major proximal or middle joints are
involved and, therefore, the appropriate weightage is given to involvement of proximal and middle joints, as
follows:
Hip= up to 35%, Knee= up to 35%, Ankle= up to 20%, dependent upon extent of involvement (mild – less than
1/3, moderate – up to 2/3, or severe – almost total).
70 THE GAZETTE OF INDIA : EXTRAORDINARY [PART II—SEC. 3(ii)]
If more than one joint of the limb is involved the mean loss of ROM in percentage should be calculated in
relation to individual joint separately and then added together to calculate the loss of mobility component in
relation to that particular limb.
2.1.3. Principle of Evaluation of Muscle Strength:
(a) The value for maximum muscle strength in the extremity is 90%.
(b) Strength of muscles can be tested by Manual Method and graded 0-5 depending upon the residual strength in the
muscle group.
(c) Manual muscle strength grading can be given percentage as below:
Numerical Score of Muscle Power Qualitative Score Loss of strength in %
0 Zero 100
1 Trace activity 80
2 Poor 60
3 Fair 40
4 Good 20
5 Normal 0
(d) Mean percentage of muscle strength loss around a joint is multiplied by 0.30 to calculate loss in relation to limb.
(e) If there has been a loss muscle strength involving more than one joint the values are added as has been described
for loss of ROM.
2.1.4. Combining values for mobility component:
The values of loss of ROM and loss of muscle strength should be combined with the help of combining formula: a+b
(90-a)/ 90 where a = higher value, b = lower value.
2.2. Stability Component
(a) Total value of the stability component is 90%
(b) It shall be tested by clinical method as given in Form B (Assessment Proforma for lower extremity) in
Appendix II. There are nine activities, which need to be tested, and each activity has a value of ten per cent
(10%). The percentage valued in relation to each activity depends upon the percentage of loss stability in
relation to each activity.
2.3. Extra Points
Extra points (% of impairment) are given for deformities, pain, contractures, loss of sensations and shortening etc.
For Shortening (true shortening and not apparent shortening)
First 1/2" Nil
Every 1/2" beyond first 1/2" 4%
Maximum extra points for associated problems such as deformity, pain, contractures etc. to be added are 10% (excluding
shortening).
(a) Deformity
In functional position 3%
In non-functional position 6%
(b) Pain
Severe (grossly interfering with function) 9%
Moderate (interfering with function) 6%
Mild (slightly interfering with function) 3%
(c) Loss of sensation
Complete Loss 9%
Partial Loss 6%
(d) Complications
¹Hkkx IIµ[k.M 3(ii)º Hkkjr dk jkti=k % vlk/kj.k 71
Superficial complications 3%
Deep complications 6%
SECTION B:
3. Guidelines for Evaluation of Permanent Physical Impairment of the Spine
Basic guidelines:
3.1. Permanent physical impairment caused by spinal injuries or deformity may change over the years, the certificate
issued in relation to spine may have to be reviewed as per the standard guidelines for disability certification.
3.2. Permanent physical impairment should be awarded in relation to the Spine.
1. TRAUMATIC LESIONS
Cervical Spine Injuries:
No. Cervical Spine Injuries Percentage of PPI in relation to the
Spine
i. 25% or more compression of one or two adjacent vertebral bodies with 20%
No involvement of posterior elements, No nerve root involvement,
moderate Neck rigidity and persistent Soreness.
ii. Posterior element damage with radiological evidence of moderate
dislocation/subluxation including whiplash injury
A) With fusion healed, No permanent motor or sensory changes
10%
B) Persistent pain with radiologically demonstrable instability.
25%
iii. Severe Dislocation:
a) Fair to good reduction with or without fusion with no residual motor 10%
or sensory involvement
b) Inadequate reduction with fusion and persistent radicular pain
15%
The additional weightage is to be added using combining formula: a+b (90-a)/ 90 (a = higher value, b = lower value).
4.6. Torso Imbalance:
In addition to the above PPI should also be evaluated in relation the torso imbalance. The torso imbalance should be
measured by dropping a plumb line from C7 spine and measuring the distance of plumb line from gluteal crease.
Deviation of Plumb line PPI
Up to 1.5 cm 4%
1.6 – 3.0 cm 8%
3.1 – 5.0 cm 16%
5.1 and above 32%
Head Tilt over C7 spine PPI
Up to 15⁰ 4%
More than 15⁰ 10%
Associated Problems as given below: To be added directly but the total value of PPI in relation to trunk should
not exceed 100%.
(a) Pain
-mildly interfering with ADL* 4%
-moderately restricting ADL 6%
-severely restricting ADL 10%
*
ADL - Activities of Daily Living
74 THE GAZETTE OF INDIA : EXTRAORDINARY [PART II—SEC. 3(ii)]
(b) Cosmetic Appearance:
-No obvious disfiguration with clothes on Nil
-mild disfigurement 2%
-severe disfigurement 4%
(c) Leg Length Discrepancy:
-First1/2 " shortening Nil
-Every1/2" beyond first1/2" 4%
(d) Neurological deficit - Neurological deficit should be calculated as per established method of evaluation of PPI in
such cases. Value thus obtained should be added using combining formula.
4.7. KYPHOSIS
Kyphosis is a larger-than-normal forward bend in the spine, most commonly in the upper back.
The normal range of thoracic kyphosis (according to the Scoliosis Research Society) is between 20°-40°, and any
curvature higher than 40° is considered abnormal.
Evaluation should be done on the similar guidelines as used for scoliosis stated above with the following modifications:
Spinal Kyphotic Deformity Permanent Physical Impairment
Less than 40⁰ Nil
41-50⁰ 10%
51-60⁰ 20%
61-70⁰ 30%
71-80⁰ 40%
81-90⁰ 50%
91-100⁰ 60%
4.8. Torso Imbalance - Plumb line dropped from external ear normally falls at ankle level.
The deviation from normal should be measured from ankle anterior joint line to the plumb line.
Less than 5 cm in front of ankle 4%
5 to 10 cm in front of ankle 8%
10 to 15 cm in front of ankle 16%
More than 15 cm in front of ankle 32%
(Add directly)
4.9. Miscellaneous conditions:
Those conditions of the spine which cause stiffness and pain etc. but are not listed above are rated as follows:
No. Condition % of PPI
i. Subjective symptoms of pain, no involuntary muscle spasm, Nil
not substantiated by demonstrable structural pathology
ii. Pain, persistent muscles spasm and stiffness of spine, 20
substantiated by mild radiological changes
iii. Same as ii. above with moderate radiological changes 25
iv. Same as ii. above with severe radiological changes involving 30
any one of the regions of spine
v. Same as iv. above involving the whole spine 40
¹Hkkx IIµ[k.M 3(ii)º Hkkjr dk jkti=k % vlk/kj.k 75
SECTION C:
5. Guidelines for Evaluation of Permanent Physical Impairment in Persons with Amputation (Amputees):
5.1. Basic Guidelines:
(a) In cases of multiple amputees, the % of permanent impairment is to be computed by using the combining
formula: a+b (90-a)/ 90 (a = higher value, b = lower value).
(b) If the stump is unfit for fitting the prosthesis additional weightage of 5% should be added to the value.
(c) Any complication in form of stiffness of proximal joint, neuroma, infection, etc., should be given upto a total of
10% additional weightage.
(d) Involvement of dominant upper limb (right upper limb in majority of individuals) in acquired amputation should
be given 10% additional weightage.
5.2. Upper Limb Amputations:
No. Level of Upper Limb Amputation % of permanent
impairment in relation to
that specific limb
1. Fore-quarter amputation 100
2. Shoulder Disarticulation 90
3. Trans Humeral (Above Elbow) upto upper 1/3 of arm 85
4. Trans Humeral (Above Elbow) upto lower 1/3 of arm 80
5. Elbow disarticulation 75
6. Trans Radial (Below Elbow) upto upper 1/3 of forearm 70
7. Trans Radial (Below Elbow) upto lower 1/3 of forearm 65
8. Wrist disarticulation 60
9. Hand through carpal bones 55
10. Thumb through C.M. or though 1st MC joint 30
11. Thumb disarticulation through metacarpophalangeal Joint or through 25
proximal phalanx
12. Thumb disarticulation through inter phalangeal joint or Through distal 15
phalanx
13. Amputation through Proximal phalanx or Disarticulation through MP joint of
Index finger 15
Middle finger 5
Ring finger 3
Little finger 2
14. Amputation through Middle phalanx or Disarticulation through PIP joint of
Index finger 10
Middle finger 4
Ring finger 2
Little finger 1
15. Amputation through Distal phalanx or disarticulation through DIP joint of
Index finger 5
Middle finger 2
Ring finger 1
Little finger 1
76 THE GAZETTE OF INDIA : EXTRAORDINARY [PART II—SEC. 3(ii)]
6. Guidelines for Evaluation of Permanent Physical Impairment of Congenital deficiencies of the extremities
Congenital limb deficiency simply means the partial or total absence of a limb at birth. These may be sporadic or
syndromic.
A variety of limb classification systems have been used over the years. The current and accepted form of classification
that has been adopted internationally since 1998 is the ISPO (International Society for Prosthetics and Orthotics)
classification system.
Common examples of congenital limb deficiencies include congenital femoral deficiency, proximal focal femoral
deficiency and congenital tibial deficiency in lower limb and congenital radial longitudinal deficiency (radial club hand)
and congenital ulnar longitudinal deficiency in upper limb.
TRANSVERSE DEFICIENCIES
6.1. Functionally congenital transverse limb deficiencies are comparable to acquired amputations and can be called
synonymously as congenital amputation. However, in some cases revision of amputation is required to fit in a prosthesis.
6.2. The transverse limb deficiencies therefore should be assessed on basis of the guidelines applicable to the evaluation
of PPI in cases of amputees as given in the preceding chapter.
For example: PPI
Transverse deficiency Rt. Arm complete (shoulder disarticulation) 90%
Transverse deficiency at thigh complete (hip disarticulation) 90%
Transverse deficiency Proximal Upper arm (Above elbow) 85%
Transverse deficiency at lower thigh (Above knee, Lower 1/3) 80%
Transverse deficiency forearm complete (elbow disarticulation) 75%
Transverse deficiency lower forearm (Below Elbow) 65%
Transverse deficiency carpal complete (wrist disarticulation) 60%
Transverse deficiency Metacarpal complete (Disarticulation
through carpal bones) 55%
¹Hkkx IIµ[k.M 3(ii)º Hkkjr dk jkti=k % vlk/kj.k 77
LONGITUDINAL DEFICIENCIES
Basic Guidelines
6.3. In cases of longitudinal deficiencies of limbs, due consideration shall be given to functional impairment.
6.4. In upper limb, loss of ROM, loss muscular strength and hand functions like prehension, etc shall be tested while
assessing the case for PPI.
6.5. In lower limb clinical method of stability component and shortening of lower limb shall be given due weightage.
6.6. Apart from functional assessment, the lost joint/part of body should also be valued as per distribution given in the
Guidelines for Evaluation of PPI in upper extremity and lower extremity amputation. The values so obtained shall be
added with the help of combining formula.
6.7. In cases of loss of single bone in forearm the evaluation shall be based on the principles of evaluation of Arm
component which include Evaluation of ROM, Muscle strength-and coordinated activities. The values so obtained shall
be added together with the help of combining formula.
6.8. In cases of loss of single bone in leg the evaluation should be based on the principles of evaluation of mobility
component and stability components of the lower extremity. The values obtained should be added together with the help
of combining formula.
SECTION D:
Guidelines for Evaluation of permanent physical impairment in persons with Club Foot and other conditions
7. Club Foot:
Clubfoot is a common deformity of the foot. It is most often noticed at birth. However, similar looking deformity can be
seen in other conditions as well. Deformity may be mild, moderate, or severe.
Severity of Clubfoot Deformity is commonly assessed in clinical settings in India using a Scoring method developed by
Shafique Pirani.
It is based on six clinical signs (three signs of hind foot and three signs of mid-foot). Each sign is scored 0 (normal), 0.5
(mildly abnormal) or 1 (severely abnormal). The amount of deformity is “scored” and recorded as “Hindfoot Score”,
“Midfoot Score” and as a summed “Total Score”.
The Hindfoot Score (HS) is the sum of the scores for Posterior Crease (PC), Rigid Equinus (RE), and Empty Heel (EH).
HS value is a measurement of contracture posteriorly from 0 (no deformity) to 3 (severe deformity).
The Midfoot Score (MS) is the sum of the scores for Medial Crease (MC), CLB, and Lateral Head of Talus (LHT). MS
value is measurement of contracture medially from 0 (no deformity) to 3 (severe deformity).
The Total Score (TS) is a sum of the HS and MS.
TS value is measurement of overall deformity from 0 (no deformity) to 6 (severe deformity).
The following scoring system using Pirani severity score for calculating disability in clubfoot:
Total Score % of Impairment
0 0
0.5 3
1 7
1.5 10
2 14
2.5 17
3 20
3.5 24
4 27
4.5 31
5 35
5.5 37
6 40
78 THE GAZETTE OF INDIA : EXTRAORDINARY [PART II—SEC. 3(ii)]
Note:-
(i) Disability is to be certified as whole number and not as a fraction.
(ii) Disability is to be certified in relation to that lower extremity.
(iii) In cases with bilateral involvement, % PPI is calculated for each side and then combining formula is used.
(iv) Total disability % will not exceed 100%.
8.1. Lymphoedema:
Chronic lymphedema is an important condition regardless if it is classified as primary or secondary and cannot simply be
described as an accumulation of protein-rich fluid. It is a chronic degenerative and inflammatory process affecting the
soft tissues, skin, lymph vessels and nodes and may result in severe and often disabling swelling.
Lymphedema may present in the extremities, trunk, abdomen, head and neck and external genitalia and can develop
anytime during the course of a lifetime in primary cases; secondary cases may occur immediately following the surgical
procedure or trauma, within a few months, a couple of years, or twenty years or more after treatment.
8.2. Its severity is assessed and graded as follows:-
• Grade 1: 5% to 10% interlimb discrepancy in volume or circumference at point of greatest visible difference;
swelling or obscuration of anatomic architecture on close inspection; pitting edema.
• Grade 2: More than 10% to 30% interlimb discrepancy in volume or circumference at point of greatest visible
difference; readily apparent obscuration of anatomic architecture; obliteration of skin folds; readily apparent
deviation from normal anatomic contour.
• Grade 3: More than 30% interlimb discrepancy in volume; lymphorrhea; gross deviation from normal anatomic
contour; interfering with activities of daily living.
• Grade 4: Progression to malignancy (e.g., lymphangiosarcoma); amputation indicated; disabling lymphedema.
Lymphoedema Grade Permanent Physical Impairment
1 Less than 10%
2 10 – 39%
3 40 – 50%
4 more than 50%
Note:-
(i) Disability is to be certified as whole number and not as a fraction.
(ii) Disability is to be certified in relation to that extremity.
(iii) In cases with bilateral/ more than one limb involvement, % PPI is calculated for each limb and then combining
formula is used.
(iv) Total disability % will not exceed 100%.
9. Charcot’s Joint
Charcot joint or neuropathic joint, or Charcot arthropathy is a progressive condition of the musculoskeletal system that is
characterized by joint dislocations, pathologic fractures, and debilitating deformities. The hallmark deformity associated
with this condition is midfoot collapse, described as a “rocker-bottom” foot.
Charcot arthropathy results in progressive destruction of bone and soft tissues at weight bearing joints; in its most severe
form, it may cause significant disruption of the bony architecture. Charcot arthropathy can occur at any joint; however, it
occurs most commonly in the lower extremity, at the foot and ankle. The Charcot foot has been documented to occur as a
consequence of various peripheral neuropathies; however, diabetic neuropathy has become the most common etiology.
Numerous classification systems exist for the categorization of the Charcot foot according to the severity/location and
complexity of the condition. Most of the classification systems of Charcot foot include radiographic and anatomical
findings; however, Lee C Roger’s classification is based on the stage/complexity and location of the Charcot foot
deformity, which offers a more prognostic view of the condition. In addition, this classification system depicts the risk
factors for amputation with increasing severity and location of Charcot foot deformity.
Given below is the % of impairment in Charcot’s arthropathy based on Roger’s classification:
¹Hkkx IIµ[k.M 3(ii)º Hkkjr dk jkti=k % vlk/kj.k 79
Location and Stage Forefoot Midfoot Rearfoot/Ankle
Acute Charcot without 15% 20% 25%
deformity
Charcot with deformity 20% 25% 30%
Charcot with deformity 30% 35% 40%
and ulceration
Charcot with deformity 40% 45% 50%
and osteomyelitis
Note:-
(i) Disability is to be certified as whole number and not as a fraction.
(ii) Disability is to be certified in relation to that extremity.
(iii) In cases with bilateral limb involvement, % PPI is calculated for each limb and then combining formula is used.
(iv) Total disability % will not exceed 100%.
SECTION E:
10. Guidelines for Evaluation of Locomotor Disability due to chronic Neurological conditions.
Basic Guidelines:
10.1. Assessment in neurological conditions is not the assessment of disease but the assessment of its effects, i.e. clinical
manifestations.
10.2. These guidelines shall only be used for central and upper motor neurone lesions.
10.3. For assessment of lower motor neurone lesions, muscular disorders and other locomotor conditions, methods of
evaluation as mentioned above will be used.
10.4. Normally any neurological assessment for the purpose of certification has to be done six months after the onset of
disease; however, exact time period is to be decided by the Medical Doctor who is evaluating the case and has to
recommend the review of certificate as given in the standard format of certificate.
10.5. Total percentage of physical impairment in any neurological condition shall not exceed 100%.
10.6. In mixed cases the highest score will be taken into consideration. The lower score will be added to it by the help of
combining formula:
a + b (90-a) / 90
10.7. Additional rating of 10% will be given for involvement of dominant upper extremity.
10.8. Additional weightage up to 10% can be given for loss of sensation in each extremity but the total physical
impairment should not exceed 100%.
Motor System Disability
11. Stroke
11.1. The modified Rankin Scale (mRS) is a commonly used scale for measuring the degree of disability or dependence
in the daily activities of people who have suffered a stroke or other causes of neurological disability.
The scale runs from 0-6, running from perfect health without symptoms to death.
• 0 - No symptoms.
• 1 - No significant disability. Able to carry out all usual activities, despite some symptoms.
• 2 - Slight disability. Able to look after own affairs without assistance, but unable to carry out all previous
activities.
• 3 - Moderate disability. Requires some help, but able to walk unassisted.
• 4 - Moderately severe disability. Unable to attend to own bodily needs without assistance, and unable to walk
unassisted.
• 5 - Severe disability. Requires constant nursing care and attention, bedridden, incontinent.
80 THE GAZETTE OF INDIA : EXTRAORDINARY [PART II—SEC. 3(ii)]
• 6 - Dead.
Mouth: Sometimes, the lips may be partly or totally destroyed, exposing the teeth. Eating and speaking can become
difficult. Up to 20%
Esophagus: Inhalation of acid vapors creating upper digestive tract problems Up to 20%
In addition, significant respiratory function impairment is to be assessed based on the guidelines as given in respective
section and weightage added depending on severity of involvement.
Miscellaneous: An additional weightage of up to 10% shall be given based on gender, age, occupation, and any other
physical impairment not mentioned above.
SECTION H:
15. Cerebral Palsy affected Persons with disabilities
15.1. Definition- "cerebral palsy" means a group of non-progressive neurological condition affecting body movements
and muscle coordination, caused by damage to one or more specific areas of the brain, usually occurring before, during
or shortly after birth.
15.2. The Gross Motor Function Classification System (GMFCS) should be used for evaluating cerebral palsy affected
individuals. It is based on self-initiated movement, with emphasis on sitting, transfers, and mobility. This is a five-level
classification system, and the primary criterion is that the distinctions between levels must be meaningful in daily life.
Distinctions are based on functional limitations, the need for hand-held mobility devices (such as walkers, crutches, or
canes) or wheeled mobility, and to a much lesser extent, quality of movement. At present, expanded and revised version
of GMFCS is available (GMFCS- E&R).
GMFCS Level Description of Mobility status % of permanent
impairment in
relation to whole
body
Level I • Can walk indoors and outdoors and Less than 40%
climb stairs without using hands for
support
• Can perform usual activities such as
running and jumping
• Has decreased speed, balance and
coordination
Note:- (i) In a person with cerebral palsy, other than problems of movement or posture, there may be other limitations
such as visual impairment, hearing impairment, speech impairment, epilepsy, mental sub-normality (low IQ) etc. These
are assessed separately as per the guidelines and the final disability % calculated using the combining formula: a+b (90-
a)/ 90 (a = higher value, b = lower value).
(ii) Total permanent physical impairment/disability % will not exceed 100%.
(iii) Disability is to be certified in relation to the whole body.
Manual Ability Classification System (MACS)
15.3. The Manual Ability Classification System (MACS) describes how children with cerebral palsy (CP) use their hands
to handle objects in daily activities. MACS describes five levels. The levels are based on the children’s self-initiated
ability to handle objects and their need for assistance or adaptation to perform manual activities in everyday life.
15.4. MACS can be used for children aged 4–18 years. MACS spans the entire spectrum of functional limitations found
among children with cerebral palsy and covers all sub-diagnoses.
15.5. Level I includes children with minor limitations, while children with severe functional limitations will usually be
found at levels IV and V. MACS levels are stable over time.
15.6. The certifying medical authority needs to know the following to use MACS:
The child’s ability to handle objects in important daily activities, for example during play and leisure, eating and
dressing, is to be considered as per the following scale:-
Level I. Handles objects easily and successfully. At most, limitations in the ease of performing manual asks requiring
speed and accuracy. However, any limitations in manual abilities do not restrict independence in daily activities.
Level II. Handles most objects but with somewhat reduced quality and/or speed of achievement. Certain activities
may be avoided or be achieved with some difficulty; alternative ways of performance might be used but manual abilities
do not usually restrict independence in daily activities.
Level III. Handles objects with difficulty; needs help to prepare and/or modify activities. The performance is slow
and achieved with limited success regarding quality and quantity. Activities are performed independently if they have
been set up or adapted.
Level IV. Handles a limited selection of easily managed objects in adapted situations. Performs parts of activities
with effort and with limited success. Requires continuous support and assistance and/or adapted equipment, for even
partial achievement of the activity.
Level V. Does not handle objects and has severely limited ability to perform even simple actions. Requires total
assistance.
SECTION I:
16. Leprosy Cured Persons with disabilities
16.1. Definition- "leprosy cured person" means a person who has been cured of leprosy but is suffering from-
(i) loss of sensation in hands or feet as well as loss of sensation and paresis in the eye and eye-lid but with no
manifest deformity;
(ii) manifest deformity and paresis but having sufficient mobility in their hands and feet to enable them to engage in
normal economic activity;
(iii) extreme physical deformity as well as advanced age which prevents him/her from undertaking any gainful
occupation, and the expression "leprosy cured" shall construed accordingly.
16.2. WHO grading of disability in Leprosy:
Highest grade for each eye or hand or foot = 2. Maximum EHF sum score = 12. (E= Eyes, H= Hands, F= Feet)
Grade Eyes Hands Feet
0 No eye problem due to leprosy; No anaesthesia, no visible No anaesthesia, no visible
no evidence of visual loss deformity or damage deformity or damage
1 Eye problem due to leprosy Anaesthesia present, but no Anaesthesia present, but no
present, but vision not severely visible deformity or damage visible deformity or damage
affected as a result of these
(vision: 6/60 or better; can count
fingers at 6 metres).
2 Severe visual impairment (vision Visible deformity or damage Visible deformity or damage
worse than 6/60, inability to count present (such as present (such as
fingers at 6 metres). Also includes cracks/wounds, claw fingers, cracks/wounds, claw toes,
lagophthalmos, iridocyclitis and wrist drop, contractures, foot drop, contractures,
corneal opacities amputation etc.) amputation etc.)
16.3. For sensory testing of hands and feet, light touch (just enough to indent the skin very slightly) of the tip of ball
point pen is recommended.
16.4. For testing loss of corneal sensation, light touch of the clean cotton wisp from the lateral side is recommended. It is
also to be noted whether blinking of the eyes is normal or not.
16.5. Muscle power is tested clinically by Voluntary Muscle testing of commonly examined peripheral nerves and graded
as per the Medical Research Council, London Scale.
EHF (Eyes, Hands, Feet) Grade Score is calculated.
Higher the Score, greater the Disability. Maximum EHF Score possible is 12.
EHF Score is 0-1, then % of Disability is up to 20%.
EHF Score is 2-3, then % of Disability is 20% to 40%.
EHF Score is 4-5 then % of Disability is 41% to 60%.
EHF Score is 6-7 then % of Disability is 61% to 70%.
EHF Score is 8-9 then % of Disability is 71% to 80%.
EHF Score is 10-11 then % of Disability is 81% to 90%.
EHF Score is 12 then % of Disability is 91 to 100%.
16.6. In a leprosy cured person with involvement of dominant upper extremity (mostly right hand), additional 10%
weightage is to be given. Total permanent physical impairment/disability % will not exceed 100%. In a leprosy cured
¹Hkkx IIµ[k.M 3(ii)º Hkkjr dk jkti=k % vlk/kj.k 87
persons, review may be done after two years, if needed or desired by the affected person, in view of likely worsening of
deformities in some persons.
SECTION J:
17. Guidelines for Evaluation of PPI in cases of Short Stature/Dwarfism:
17.1. Definition.- "Dwarfism" means a medical or genetic condition resulting in an adult height of 4 feet 10 inches (147
centimeters) or less.
17.2. The evaluation of a short statured person shall be considered irrespective of whether it is of proportionate variety or
disproportionate variety and is accompanied by an underlying pathological conditions,
Every 1" vertical height reduction shall be valued as 4% permanent physical Impairment in relation to whole body.
Associated skeletal deformities such as contractures or deformities shall be evaluated, separately and total percentage of
both shall be added by combining formula.
SECTION K:
18. Muscular Dystrophy
18.1. Definition.- "muscular dystrophy" means a group of hereditary genetic muscle disease that weakens the muscles
that move the human body and persons with multiple dystrophy have incorrect and missing information in their genes,
which prevents them from making the proteins they need for healthy muscles. It is characterised by progressive skeletal
muscle weakness, defects in muscle proteins, and the death of muscle cells and tissue.
18.2. After detailed clinical examination, each of the features namely, weakness, contractures, scoliosis, cardiac or
pulmonary involvement are evaluated and disability is computed based on the criteria for each of these and added to the
locomotor disability component, using the combining formula: a + b (90-a)/ 90 (a = higher value, b = lower value).
Disability is to be expressed in relation to the whole body. Total % of disability will not exceed 100%. Due to
progressive nature of this disease, review may be necessary after a period, such as 2 years or as desired by the patient or
as decided by the disability board.
18.3 Medical Authority and instruments required for certification of locomotor disability
18.3.1 The Medical Superintendent or Chief Medical Officer or Civil Surgeon or any other equivalent authority as
notified by the State Government shall be the head of the certification board for the purpose of certification of locomotor
disability including cerebral palsy, leprosy cured, dwarfism, acid attack victims and muscular dystrophy. The Board shall
comprise of:
(i) Medical Superintendent or Chief Medical Officer or Civil Surgeon
(ii) Specialist in Physical Medicine and Rehabilitation or Specialist in Orthopedics
(iii) One specialist as nominated by Chief Medical Officer as per the condition of the person with disability.
18.3. 2. The most important resource is the knowledge and skill of the Members/Experts involved in the process.
However, a few items listed below may also be required:
a. A measuring tape for measuring – vertical height of the person, degree of chest expansion, shortening of an
extremity, or difference in girth of a limb etc.,
b. Goniometers – small, medium and large, for measuring range of motion at different joints,
c. Hand-held dynamometer,
d. Clean cotton piece for testing corneal sensation,
e. A ball point pen for testing sensory deficit e.g., in leprosy-cured person,
f. X-ray films, e.g., in cases with spinal deformity, amputation, arthritis, club foot, congenital limb deficiency,
fractures etc.
• For Visual acuity the line should be read completely, in case of partial line read, one line below that line should
be taken for visual acuity.
90 THE GAZETTE OF INDIA : EXTRAORDINARY [PART II—SEC. 3(ii)]
Matrix Table
6/6 to HMCF to
6/24 6/36 6/60 3/60 2/60 1/60
6/18 PL-
Right Eye Vision [Best Corrected Visual Acuity (BCVA)]
HMCF to
30% 60% 60% 60% 80% 90% 90% 100%
PL-
• Yellow- Right eye is Better eye Brown- Left eye is better eye
• Percent disability is marked inside the box corresponding to the visual acuity for both eyes
Field of Vision around centre of fixation
Left Eye
<40° to <20° to
<10°
20° 10°
<40° to
40% 50% 60%
20°
Right Eye
<20° to
50% 70% 80%
10°
• Yellow- Right eye is Better eye Brown- Left eye is better eye (only better eye Fields to be taken in to
account for determining the %)
19.4. Medical Authority.
The medical authority shall comprise of one ophthalmologist and certificate of disability shall be countersigned by
Medical Superintendent or Chief Medical Officer or Civil Surgeon or any other equivalent authority as notified the State
Government.
¹Hkkx IIµ[k.M 3(ii)º Hkkjr dk jkti=k % vlk/kj.k 91
III A. HEARING IMPAIRMENT (DEAF AND HARD OF HEARING)
20.1. Definition:
(a) “Deaf" means persons having 70 DB hearing loss in speech frequencies in both ears;
(b) "Hard of hearing" means person having 60 DB to 70 DB hearing loss in speech frequencies in both ears;
20.2. Guidelines for Assessment:
20.2.1. Measurement Air Conduction Thresholds (ACT):
(a) ACT is to be measured using standard Pure Tone Audiometry by an Audiologist for Right Ear and Left
Ear separately.
(b) In case of non-reliable ACT, additional tests are recommended such as Immittance, and Speech
audiometry or Auditory Brainstem Response (ABR) Testing.
(c) Measuring ACT may be difficult in children aged 3-5 years. In such cases, Conditioned Pure Tone
audiometry/Visual Reinforcement Audiometry (VRA) shall be conducted. ABR or Auditory Steady
State Response (ASSR) testing can be advised for the estimation of ACT in infant and young children.
20.2.2 . Computation of Percentage of Hearing Disability:
(a) Monaural Percentage of Hearing Disability
(i) Calculate Pure tone average of ACT for 500 Hz, 1000 Hz, 2000 Hz, 4000 Hz for Right Ear and Left ear
separately (whenever there is no response at any frequency ACT is to be considered as 95dB).
(ii) Monaural percentage of hearing disability is to be calculated as per the ready reckoner given below
separately for Right Ear and Left Ear.
20.3.1. Definition: "Speech and language disability" means a permanent disability arising out of conditions such as
laryngectomy or aphasia affecting one or more components of speech and language due to organic or neurological
causes
20.3.2. Conditions affecting Speech Components for which Speech Disability certificate can be issued
• Laryngectomy
• Glossectomy
• Bilateral vocal cord paralysis
• Maxillofacial anomalies
• Dysarthria
• Apraxia of Speech
20.3.3. Computation of Percentage Speech Disability
(a) Speech Intelligibility Test
The verbal output of person should be evaluated using either Perceptual Speech intelligibility rating scale (AYJNISHD,
2003) or Perceptual Rating Scale (SRMC, Chennai) and percentage of Speech Intelligibility Affected (SIA) to be
measured based on score as given below:
Score Percentage of Speech Intelligibility
Affected (SIA)
1 0-15
2 16-30
3 31-39
4 40-55
5 56-75
6 76-89
7 90- 100
(b) Voice Test
Consensus Auditory Perceptual Evaluation of Voice (CAPE-V) orDysphonia Severity Index (DSI) can be used for
measuring percentage of Overall Voice Clarity Affected (OVCA) which includes roughness, breathiness, strain,
pitch and loudness. Average score to be given weighted for the percentage of overall voice clarity affected
Score Percentage of overall voice clarity
affected (OVCA)
1 0-15
2 16-30
3 31-39
4 40-55
5 56-75
6 76-89
7 90-100
¹Hkkx IIµ[k.M 3(ii)º Hkkjr dk jkti=k % vlk/kj.k 93
20.4.4. Medical Authority. The Medical Superintendent or Chief Medical Officer or Civil Surgeon or any other
equivalent authority as notified by the State Government shall be the head of the certification medical authority for the
purpose of certification of hearing disability, and speech and language disability. The certification medical authority shall
comprise of:
(i) Medical Superintendent or Chief Medical Officer or Civil Surgeon or any other equivalent authority
(ii) ENT Specialist
(iii) One specialist (audiologist/speech language pathologist) as nominated by the Medical Superintendent
or Chief Medical Officer or Civil Surgeon or any other equivalent authority as notified by the State
Government.
22.4. Diagnostic Tool - National Institute for Mental Health and Neurosciences (NIMHANS) battery shall be applied
for diagnostic test for SLD.
22.5. Medical Authority: The Medical Superintendent or Chief Medical Officer or Civil Surgeon or any other equivalent
authority as notified by the State Government shall be head the certification authority. The medical authority will
comprise of:
(a) The Medical Superintendent or Chief Medical Officer or Civil Surgeon or any other equivalent
authority as notified by the State Government
(b) Pediatrician or Pediatric Neurologist (where available)
(c) Clinical or Rehabilitation Psychologist
(d) Occupational therapist or Special Educator or Teacher trained for assessment of SLD.
22.6. Validity of Certificate: The certification will be done for children aged eight years and above only. The child will
have to undergo repeat certification at the age of 14 years and at the age of 18 years. The certificate issued at 18 years
will be valid life-long.
Figure 1. The suggested flow for identification and certification of Children with suspected Intellectual Disability
96 THE GAZETTE OF INDIA : EXTRAORDINARY [PART II—SEC. 3(ii)]
Figure 2. The suggested flow for identification and certification of Children with suspected Specific Learning Disability.
V. MENTAL ILLNESS
23.1. Definition: "mental illness" means a substantial disorder of thinking, mood, perception, orientation or memory that
grossly impairs judgment, behaviour, capacity to recognise reality or ability to meet the ordinary demands of life, but
does not include retardation which is a condition of arrested or incomplete development of mind of a person, specially
characterised by subnormality of intelligence.
23.2. The examination process will consist of components as required namely, clinical assessment, IDEAS scale
and/or IQ assessment.
23.3. Indian Disability Evaluation and Assessment Scale (IDEAS) administration (see Appendix IV) is to be used for
mental illness.
23.4. In some cases where there is suspicion of intellectual deficits or additional intellectual evaluation is required for
any reason, Standardised IQ test may be carried out. Categories on IQ score will be:
(i) Mild Mental Disabilities: The range of 50 to 69 (standardised IQ test) is indicative of mild
disability.
(ii) Moderate Mental Disability: The IQ is in the range of 35 to 49
(iii) Severe Mental Disability: The IQ is in the range of 20 to 34.
(iv) Profound Mental Disability: The IQ in this category estimated to be under 20.
¹Hkkx IIµ[k.M 3(ii)º Hkkjr dk jkti=k % vlk/kj.k 97
23.5. In cases where the mental behavioural condition requires only IDEAS, then only IDEAS can be administered
and degree of disability certified.
23.6. In cases where the mental behavioural condition requires only IQ, then a standardised IQ test shall be used to
certify degree of disability.
23.7. In some cases, only one test may not estimate disability comprehensively. Such a person may have borderline or
normal score on one test with disability score on the other. In such cases both IQ and IDEAS shall be used, the score
indicating more severe disability should be the degree of disability for that person.
24. Medical Authority: The Medical Superintendent or Chief Medical Officer or Civil Surgeon or any other equivalent
authority as notified by the State Government shall be head of the certification authority with the following two other
members:-
(a) Psychiatrist for clinical assessment,
(b) Trained psychologist to administer IQ tests.
25.1. Definition:
Chronic neurological conditions, such as—
(i) "multiple sclerosis" means an inflammatory, nervous system disease in which the myelin sheaths around the axons
of nerve cells of the brain and spinal cord are damaged, leading to demyelination and affecting the ability of nerve
cells in the brain and spinal cord to communicate with each other;
(ii) "parkinson's disease" means a progressive disease of the nervous system marked by tremor, muscular rigidity, and
slow, imprecise movement, chiefly affecting middle-aged and elderly people associated with degeneration of the
basal ganglia of the brain and a deficiency of the neurotransmitter dopamine.
25.2. The disability caused due to chronic neurological conditions such as multiple sclerosis, parkinsons disease is multi
dimensional involving manifestation in muscular skeleton system and also psycho social behaviour. The disability in
musculo-skeletal system on account of these conditions shall be assessed in terms of Section E (para 10-10.8 of
Annexure II) of these guidelines relating to assessment of locomotor disability due to chronic neurological conditions and
the psychosocial disability (mental illness) shall be assessed by using the IDEAS as at Appendix IV. Comprehensive
disability on account of these conditions shall then be calculated by using the formula a + b (90-a).
90
Where “a” will be the higher score and
And “b” will be the lower score. However, the maximum total percentage of multiple disabilities shall
not exceed 100%.
25.3. Neurological conditions which are reversible and without sequel are not certifiable. Only neurological conditions
which are permanent are certifiable. Permanent disability certificate can be issued in irreversible/progressive cases. If
needed in specific cases, a re-evaluation of disability can be done after a period of one year.
25.4. The disability certificate shall mention Chronic Neurological Conditions (name of disease).
25.5. Medical Authority: The Medical Superintendent or Chief Medical Officer or Civil Surgeon or any other
equivalent authority as notified by the State Government shall be the head of the certification authority with the
following two other members:-
(a) Pediatrics for childhood chronic neurological conditions/psychiatrist for mental illness due to chronic
neurological conditions/neurologist for chronic neurological conditions without mental illness
(b) Specialist for certifying locomotor disability
(c) Trained psychologist (clinical or rehabilitation) to administer IQ test
98 THE GAZETTE OF INDIA : EXTRAORDINARY [PART II—SEC. 3(ii)]
25.6. Standardized IQ test may be carried out if required. Categories on IQ score will be:
(a) Mild Disability: The range of 50 to 69 (standardized IQ test) is indicative of mild disability.
(b) Moderate Disability: The IQ is in the range of 35 to 49.
(c) Severe Disability: The IQ is usually in the range of 20 to 34.
(d) Profound Disability: The IQ in this category estimated is to be lesser than 20.
25.7. In cases where the chronic neurological condition requires only IDEAS, then only IDEAS can be administered and
degree of disability certified.
25.8. In cases where the chronic neurological condition requires only IQ, then a standardized IQ test should be used to
certify degree of disability.
25.9. In some cases, only one test may not estimate disability comprehensively. Such a person may have borderline score
on one test with marked disability score on the other. In such cases both IQ and IDEAS shall be used. The score
indicating more severe disability shall be the degree of disability for that person.
37. Thalassemia
37.1. Thalassaemia refers to group of blood diseases characterized by decreased or absent synthesis of globin chains.
Most thalassaemia are inherited as recessive traits. From clinical point of view most relevant types are α and β
thalassaemias. Currently based on their clinical severity and transfusion requirement, these thalassaemia syndromes can
be classified phenotypically into two main groups; transfusion dependent thalassaemias (TDTs) and Non-transfusion
dependent thalassaemias (NTDTs).
37.2. Screening is based on estimation of Hemoglobin (Hb) by digital Hemoglobinometer and NESTROFT (Naked eye
single tube osmatic fragility test) as the primary screening test, followed by Complete Blood Counts (CBC) and HPLC
test, for the screen positive cases. Serum Ferritin is done in required cases to confirm concomitant iron deficiency anemia
in suspected thalassemia carriers.
37.3. The guiding elements of National Health Mission (NHM) Guidelines on Hemoglobinopathies are-
(1) Haemoglobinopathies are genetic disorders with an autosomal recessive inheritance implying that
(a) They are equally prevalent in males and females
(b) Have a ‘carrier’ and ‘disease’ state
(c) The abnormal gene is passed on from one generation to another
(2) The carrier state refers to a person carrying only one abnormal gene. Such individuals do not have any disease and
clinically have no symptoms,
(3) The disease state occurs when an individual’s both genes are abnormal, one abnormal gene being inherited from
each of the parents.
(4) A couple where both the partners are carriers of an abnormal gene (mutated gene)
(a) have a 25% risk in each pregnancy of giving birth to a child with disease state.
(b) have 25% chance in every pregnancy of having a ‘normal’ child.
(c) have a 50% chance in each pregnancy to give birth to a ‘carrier’ child.
102 THE GAZETTE OF INDIA : EXTRAORDINARY [PART II—SEC. 3(ii)]
Thus, a carrier couple can have ‘normal’, ‘carrier’ or ‘disease’ affected children.
(5) Thalassemia Major, and Thalassemia Intermedia are the major disorders that require lifelong management and
are to be considered for prevention.
(6) Untreated Thalassemia Major is invariably fatal by 2-5 years of age. Commonly Thalassemia Major (TM) is
managed by regular blood transfusions (Packed Red Blood Cells) and iron chelation therapy. Availability of
leuko-depleted packed red blood cells (pRBC) and iron chelators are to be ensured for adequate management
along with facilities for regular monitoring. Adequately treated patients can live a fulfilling life.
(7) It is possible to know whether the child to be born will be affected by disease, or be a carrier or normal by
detecting the mutations of both parents in the fetal tissue. The process is called Prenatal Diagnosis (PND).
Thalassemia Major is a severe and life threatening disease, hence, termination of pregnancy is permitted under
Indian laws.
(8) Newborn screening can detect abnormal hemoglobin variants. On the other hand, thalassemia major is difficult
to detect by newborn screening and can be detected hematologically mostly after 3-6 months of age and
confirmed at one year of age.
(9) Carrier state is asymptomatic, but can be detected by relatively simple blood tests, opening up the possibility of
controlling hemoglobinopathies by preventing birth of affected children.
(10) Cost effective population screening programmes are possible for detection of carriers, as low cost screening tests
with high negative predictive value are available for detection of carriers of β-thalassemia.
37.4. DETECTION AND DIAGNOSIS OF Thalassemia-Appendix VI
(a) -Complete Blood Counts (CBC)
(b) Severe anemia with microcytic hypochromic red cell indices
(Hb<7g/dl; MCV: 50-70fl; MCH: 12-20pg; )
(c) Peripheral blood smears:
(d) RBCs showing anisopoikilocytosis (tear drop cells, target cells), microcytosis hypochromia, and nucleated red
cells markedly increased in relation to degree of anemia
(A) Hemoglobin (HPLC),
HPLC pattern in β-thalassemia: HbA : 0-30% HbF : 70-100% HbA2 : 2-5%
(B) Normal Values:
Hb: 12-17 gm/dl, MCV: 80-100 fl, MCH:27-32 pg, Normocytic Normochromic
HbA: 96-98%, HbF: <2%, HbA2: 2.3-3.3%
(C) Transfusion Regimen: Pre-transfusion Hemoglobin (Hb) should be kept between 9- 10.5 g/dl.
The frequency of transfusions varies from every 2-4 weeks depending on the age, weight of child and other
factors.
(D) Evaluation of Iron Overload:
(i) Serum Ferritin: Serum ferritin reflects the overall iron stores in the body tissues.
(ii) MRI of liver and heart
(iii) Liver Biopsy
The serum ferritin levels shall be assessed after 10 to 15 transfusions and chelation therapy should be initiated when the
serum ferritin value is more than 1000µg/L.
Serum ferritin and Echocardiography should be made available at most of district hospital.
37.5. COMPLICATIONS OF IRON OVERLOAD, MULTIPLE TRANSFUSION AND INDICATIONS OF
SPLENECTOMY
(a) Even with adequate iron chelation patients may go on to develop complications. Iron overload results in toxicity
to the heart, liver, and harms the endocrine system- affecting growth and development.
(b) It can even result in skeletal and bone mineralization problems.
(c) The patients may be affected by transfusion transmitted diseases like hepatitis B, C or HIV.
(d) Toxicity from iron chelation medicines, if occurs may also need to be managed.
(e) Therefore, a multi-specialist team including a pediatrician, cardiologist, gastroenterologist, and endocrinologist
are necessary.
(f) Psychological counseling and support are needed to deal with the consequences of a chronic disease.
(g) Splenectomy is needed only in few cases where hypersplenism is symptomatic and BT requirement exceeds
>250 CC of packed cell RBC/kg/year requirement. Splenectomy is associated with many late complications.
¹Hkkx IIµ[k.M 3(ii)º Hkkjr dk jkti=k % vlk/kj.k 103
38. Scoring system for assessment of disability
(a) Mild anemia refractory to iron supplementation, and microcytic hypochromic with hepatosplenomegaly and
confirmed by Hb electrophoresis but asymptomatic and no BT# requirement
(b) Thalssaemia Major with monthly BT# requirement but Haemoglobin maintained at 10 –should receive some
benefit like time out, special leave, social security and free treatment-TRANFUSION DEPENDANT and
exertional dyspnoea on walking few yards more than class 2 as per NYHA and AHA
(c) Above plus Thal-major with monthly BT# with signs of bone marrow hyperplasia and osteoporosis decided by
bone Dexa scan
(d) Note at this stage should be seen by mutidisability board and should be seen by orthopedician.
(e) above plus Iron chelator requirement osteoporosis and Serum ferritin less than 1000ng/ml
(f) Thal major as in level 4 plus with Bimonthly BT# requirement and all the above
(g) 6.Thal major > than bimonthly BT requirement with features of hyperspenism and more than 250 ML packed
cell transfusion/Kg per year plus features of level 5
(h) 7. Thal major with splenctomy with infection and plus features as in level 6
(i) Thal major with features as above at level 7 plus haemosiderosis and serum ferritin level > 1000ng/ml and with
multi organ failure decided by Echocardiogram, LFT and GTT
(j) Th major with features at level 8 plus with BT associated infections like HBV, CMIV, HIV, HBC etc
38.1. DISABILITY GRADING
At level 1 -< 40%
At level 2 - 41-50%
At level 3 -51-60%
At level 4 -61-65%
At level 5 -66-70
At level 6- 71-75%
At level 7 -76-79%
At level 8 -80-85%
At level 9 ->85%
38.2. In nutshell- when diagnosis of Thalassemia major confirmed by appropriate clinical examination and laboratory
tests as specified above and has progressive pallor with Hb persistently low ie <7gm% and have failure to thrive and
require regular BT to maintain Hb above 10 shall be entry point for disability eligibility and with passage of time, as and
when new complications develops disability shall be reassessed as mentioned above and higher score should be awarded.
# BT principles
-i) should be from voluntary donor, matched for major blood group like ABO and Rh plus C,E and kell preferably
ii) Should be leucodepleted
iii) screened for HIv, hepatitis B and C
iv) PCV should be around 70% in transfused blood
v) transfused volume should be 12-15ml.kg over 3-4 hours
vi) should be monitored for febrile reaction
vii) should not be more than one week old
viii) should have CPD 1 as anticoagulant
ix) washed RBC or irradiated RDC or RBC obtained by apheresis are better and desirable
39. Haemophilia
39.1. What is Haemophilia:
(a) Haemophilia is an X-linked congenital bleeding disorder caused by a deficiency of coagulation factor VIII
(FVIII) (in hemophilia A) or factor IX (FIX) (in hemophilia B).
(b) The deficiency is the result of mutations of the respective clotting factor genes.
(c) Hemophilia has an estimated frequency of approximately one in 10,000 births.
(d) Estimations based on the WFH’s annual global surveys indicate that the number of people with hemophilia in
the world is approximately 4,00,000
(e) Hemophilia A is more common than hemophilia B, representing 80–85% of the total hemophilia population.
(f) Hemophilia generally affects males on the maternal side. However, both F8 and F9 genes are prone to new
mutations, and as many as 1/3 of all cases are the result of spontaneous mutation where there is no prior family
history
(g) Accurate diagnosis of hemophilia is essential to inform appropriate management.
(h) Hemophilia should be suspected in patients presenting with a history of:
(i) Easy bruising in early childhood
104 THE GAZETTE OF INDIA : EXTRAORDINARY [PART II—SEC. 3(ii)]
(ii) “spontaneous” bleeding (bleeding for no apparent/known reason), particularly into the joints, muscles,
and soft tissues or brain
(iii) Excessive bleeding following trauma or surgery
(i) A family history of bleeding is obtained in about two-thirds of all patients.
(j) A definitive diagnosis depends on factor assay to demonstrate deficiency of Factor VIII or Factor IX.
(k) But disease can be suspected with family history, male child with echymosis or bleed without any obvious or
trivial trauma and abnormal activated partial thromboplastin time(aPTT) and normal platelet count and
Prothombin time
39.2. Bleeding manifestations
The characteristic phenotype in hemophilia is the bleeding tendency.
(a) Some patients may not bleed throughout life.
(b) Patients with mild hemophilia may not bleed excessively until they experience trauma or surgery.
(c) The severity of bleeding in hemophilia is generally correlated with the clotting factor level
(d) Most bleeding occurs internally into the joints or muscles
(e) Some bleeds can be life-threatening and require immediate treatment
39.3. Eligibility for certification
(a) History (including family history) especially males being affected and females are spared
(b) Review of previous medical records
(c) Physical examination
(d) Baseline coagulation profile (prothrombin time, partial thromboplastin time and thrombin time)
(e) Factor assay (if available)
39.4. Confirmation of diagnosis individual factor assay from recognized laboratory shall be made available (Appendix
VII)
39.5. Disability grading shall be as follows:-
For example, if the percentage of hearing disability is 30% and visual disability is 20%, then by applying the
combining formula given above, the total percentage of multiple disabilities will be calculated as follows:-
30 + 20(90-30) = 43%
90
40.2.3 For certifying more than two disabilities, each disability will be evaluated and the degree of disability will be
calculated by the notified Specialists in the area. Based on the score received for each disability, they will be graded
from the most severe to the least severe. The formula:
a + b (90-a)
90
will be successively applied to subsequent disability till the last disability is covered. This calculation is subject to
maximum of 100%.
For example a person may have disabilities 1, 2 and 3, the score for 1 is the highest equal to (a); score for the second is
equal to (b) (second highest); and score for 3 is (c) the lowest score. According to the above formula:
a + b (90-a) = x
90
(score of disability 1 and 2 = x)
This (x) will become (a) for the purpose of calculation of disability 3 which is C.
x + c (90-x) = y
90
(score of disabilities 1, 2 and 3 = y)
Such calculation will continue till the last disability is covered subject to a maximum of 100%.
41. Medical Authority
The certification medical authority for certifying multiple disability shall comprise of the following:-
(a) The Medical Superintendent or Chief Medical Officer or Civil Surgeon or any other equivalent authority as
notified by the State Government – Chairperson
(b) Specialist required for assessing the disabilities as per the requirement of respective guidelines.
Appendix I
[see paragraph 1.2.3(a)]
Muscle strength grading (Medical Research Council- MRC Scale):
Grade Description
0 No contraction of muscle being tested
1 Flicker or trace of contraction of muscle being tested
2 Active contraction of the muscle with gravity eliminated
3 Active contraction of the muscle against gravity
4 Active contraction of the muscle against gravity and resistance
5 Normal strength
¹Hkkx IIµ[k.M 3(ii)º Hkkjr dk jkti=k % vlk/kj.k 107
Appendix II
[see paragraph 1.2.4 (b) and 2.2(b)]
FORM A:
ASSESSMENT PROFORMA FOR UPPER EXTREMITY
Name ___________..Age_______.Sex_____.
Reg. No. ........................................
Diagnosis______.
Address____________
O.P.D________.Deptt_________.
ARM COMPONENT (Total Value 90%)
ARM Component Normal Rt. Lt. Loss Loss Mean Sum Combining %
COMPONENT of of % of % value Rt. Summary
Value Side Side
loss loss Lt. value for
% %
(Degrees) Rt. Rt. component
Rt. Lt. Lt. Lt.
Side Side
Range of
Movement
(Active) Value
90%
Shoulder
Range of
Movement
(Active) Value
90%
Elbow
Range
of
Movement
(Active) Value
90%
Wrist
Muscle 1. Flexion
Strength Value 2. Extension
90% 3. Rotation -
Shoulder Ext
4. Rotation -
Int.
5. Abduction
6. Adduction
108 THE GAZETTE OF INDIA : EXTRAORDINARY [PART II—SEC. 3(ii)]
Muscle 1. Flexion
Strength Value 2. Extension
90% 3. Pronation
Elbow 4. Supination
Muscle 1. Dors Flexion
Strength Value 2. Palmar
90% Flexion
Wrist 3. Radial
Deviation
4. Ulnardeviatior
Coordinated 1. Lifting
overhead objects
Activities
remove and
Value 90% placing at the
same place 9%
2. Touching nose
with end of
extremity 9%
3. Eating Indian
Style 9%
4. Combing and
Plaiting 9%
5. Putting on a
shirt/kurta 9%
6. Ablution glass
of water 9%
7. Drinking Glass
of water 9%
8. Buttoning 9%
9 Tie Nara Dhoti
9%
10. Writing 9%
Summary value for upper extremity is calculated from component and hand component values.
Add 10% for dominant extremity.
10% Additional weightage to be given to infection, deformity, malalignment, contracture, cosmetic appearance and
abnormal mobility.
Form B
ASSESSMENT PROFORMA FOR LOWER EXTREMITY
Name ___________..Age_______.Sex_____.
Reg. No. ........................................
Diagnosis______....................................................................................................
Address____________............................................................................................
O.P.D________.Deptt_________.
MOBILITY COMPONENT (Total Value (90%)
Joint Component Normal Rt. Lt. Loss Loss Mean Mean Combining %
Rt. value Rt. Summary
Value Side Side of of %
Lt. value of
Lt.
% % Rt. mobility
component
Rt. Lt. Lt.
Side Side
Range of
Movement
(Active)
HIP
Range of
Movement
(Active)
Knee
Range of
Movement
(Active)
Ankle &
Foot
110 THE GAZETTE OF INDIA : EXTRAORDINARY [PART II—SEC. 3(ii)]
Muscles
Strength
HIP
Muscles
Strength
KNEE
Muscles
Strength
ANKLE &
FOOT
Appendix III
[see paragraph 1.2.4(d)]
Average Normal Range (degrees) at different Joints:
Joint Movement Average Normal Range
(degrees)
Shoulder Flexion 0-180
Extension (hyper) 0-50
Abduction 0-180
Adduction 0-50
Medial (Internal) rotation 0-80
Lateral (External) rotation 0-90
Elbow Flexion 0-150
Extension 0
Forearm Pronation 0-80
Supination 0-85
Wrist Flexion 0-80
Extension 0-70
¹Hkkx IIµ[k.M 3(ii)º Hkkjr dk jkti=k % vlk/kj.k 111
Radial deviation 0-20
Ulnar deviation 0-50
Thumb CMC Abduction 0-70
Flexion 0-15
Extension 0-20
Opposition Tip of thumb to base or tip of fifth
digit
Thumb MCP Flexion 0-50
Thumb IP Flexion 0-80
Digits 2-5 Flexion 0-90
MCP
Extension 0-30
PIP Flexion 0-90
DIP Flexion 0-90
Hyperextension 0-10
Appendix IV
[see paragraph 23.3 and 25.2]
Indian Disability Evaluation and Assessment Scale (IDEAS)
Indian Disability Evaluation and Assessment Scale (IDEAS) is a scale for measuring and quantifying disability in mental
disorders, to be used for assessment of disability related to mental illness, as given below.
Items -
I. Self Care: Includes taking care of body hygiene, grooming, health including bathing, toileting, and dressing, eating,
and taking care of one's health.
II. Interpersonal Activities (Social Relationships): Includes initiating and maintaining interactions with others in
contextual and social appropriate manner.
III. Communication and Understanding: Includes communication and conversation with others by producing and
comprehending spoken/written/non-verbal messages.
IV. Work: Three areas are Employment/Housework/ Education Measures on any aspect.
1. Performing in Work/Job: Performing in work/employment (paid) employment/self-employment/
family concern or otherwise. Measure ability to perform tasks at employment completely and
efficiently and in proper time. Includes seeking employment.
2. Performing in Housework: Maintaining household including cooking, caring for other people at home,
taking care of belongings etc. Measures ability to take responsibility for and perform household tasks
completely and efficiently and in proper time.
3. Performing in school/college: Measures performance education related tasks.
Scores for each item:
0- NO disability (none, absent, negligible)
1- MILD disability (slight, low)
2- MODERATE disability (medium, fair)
3- SEVERE disability (high, extreme)
4- PROFOUND disability (total cannot do)
TOTAL SCORE : Add scores of the above 4 items (self-care, interpersonal activities, communication and
understanding, and work) and obtain a total score
Global Disability -
Total Disability score + DOI score = Global Disability Score Percentages:
0 No Disability = 0%
1-6 Mild Disability = < 40 %
7-13 Moderate Disability = 40 - 70 %
14-19 Severe Disability = 71-99%
20 Profound Disability = l00%
Cut off for welfare measures = 40%
Manual for "IDEAS"
In order to score this instrument, information from all possible sources should be obtained. This will include interview of
patient, the care given and case notes when available.
I. SELF CARE: This should be regarded as activity guided by social norms and conventions. The broad areas covered
are
a. Maintenance of personal hygiene and physical health.
b. Eating habits
c. Maintenance of personal belongings and living space
d. Does s/he look after himself, wash his clothes regularly, take a bath and brush his teeth?
e. DOES s/he have regular meals?
f. Does s/he take food of right quality and quantity?
g. What about her/his table manners?
h. Does s/he take care of personal belongings with reasonable standard of cleanliness and orderliness?
0 = No disability: Patient's level and pattern of self-care are normal, within the social cultural and economic
context.
1 = Mild: Mild deterioration in self-care and appearance (not bathing, shaving, changing clothes for the
occasion as expected). Does not have adverse consequences such as hazards to her/his health. No
embarrassment to family.
2 = Moderate: Lack of concern for self-care should be clearly established such as mild deterioration of physical
health, obesity, tooth decay & body odours.
3 = Severe: Decline in self-care should be marked in all areas. Patient wearing torn clothes would only wash if
made to and would only care if told. Evidence of serious hazards to physical health. (Malnutrition, infection,
patient unacceptable in public).
4 = Profound: Total or near total lack of self-care (Example: risk to physical survival, needs feeding, washing,
putting on clothes etc., constant supervision necessary)
II. Inter Personal Activities
Includes patient's response to questions, requests and demands of others, activities or regulating emotions, activities of
initiating, maintaining and terminating interactions and activities of engaging in physical intimacy.
Guiding Questions
a. What is her/his behaviour with others?
b. Is s/he polite?
c. Does s/he respond to questions!
d. Is s/he able to regulate verbal and physical aggression?
e. Is s/he able to act independently in social interactions?
f. How does s/he behave with strangers?
g. Is s/he able to maintain friendship?
h. Does s/he show physical expression of affection and desire?
Scoring
0= No : Patient gets along reasonably well with people, personal relationships. No friction in inter-personal
relationships.
114 THE GAZETTE OF INDIA : EXTRAORDINARY [PART II—SEC. 3(ii)]
1= Mild : Some friction on isolated occasions. Patient known to be nervous or irritable but generally tolerated
by others.
2= Moderate: Factual evidence that pattern of response to people is unhealthy. May be seen or more than few
occasions. Could isolate herself/himself from others and avoid company.
3= Severe: Behaviour in social situations is undesirable and generalized. Causes serious problems in daily
living/or work. Patient is socially ostracized.
4= Profound: Patient in serious and lasting conflict, serious danger to problems of others. Family afraid of
potential consequences.
III. Communication and Understanding
Understanding spoken messages as well as written and non-verbal messages and ability to deduce messages in order to
communicate with others.
1. Questions
a. Does s/he avoid talking to people?
b. When people come home what does s/he do?
c. Does s/he ever visit others?
d. Is s/he able to start, maintain and end a conversation?
e. Does s/he understand body language and emotions of others such as smiling, crying, screaming, etc.,
f. Does s/he indulge in reading and writing?
g. Do you encourage her/him to be more sociable?
Scoring:
0 = No disability: Patient mixes, talks and generally interacts with people as much as can be expected in
her/his socio-cultural context. No evidence of avoiding people.
1= Mild: Patient described as uncommunicative or solitary in social situations. Signs of social anxiety might be
reported.
2= Moderate: A very narrow range of social contacts, evidence of active avoidance of people on some
occasions and interference with performance of social rules causes concern to family.
3= Severe: Evidence of more generalized, active avoidance of contact with people (leave the room when
visitors arrive and would not answer the door or phone).
4= Profound: Hardly has any contacts and actively avoids people nearly all the time. Eg : may lock
herself/himself inside the room. Verbal communication is nil or a bare minimum.
IV. Work
This includes employment, housework and educational performance. Score only one category in case of an overlap.
Employment:
Guiding Questions
a. Is s/he employed/unemployed?
b. If employed, does s/he go to work regularly?
c. Does s/he like his job and coping well with it?
d. Can you rely on her/him financially?
e. If unemployed, does s/he make efforts to find job?
Scoring:
0= No disability: Patient goes to work regularly and output and quality of work performance are within
acceptable levels for the job.
1= Mild: Noticeable decline in patient's ability to work, to cope with it and meet the demands of work. May
threaten to quit.
2= Moderate: Declining work performance, frequent absences, lack of concern about all this. Financial
difficulties foreseen.
3= Severe: Marked decline in work performance, disruptive at work, unwilling to adhere to disciplines of work.
Threat of losing his job.
¹Hkkx IIµ[k.M 3(ii)º Hkkjr dk jkti=k % vlk/kj.k 115
4= Profound: Has been largely absent from work, termination imminent. Unemployed and making no efforts to
find jobs.
In similar ways, housewives should be rated on the amount, regularity and efficiency in which tasks in the following
areas are completed. Consider the amount of help required completing these. Acquiring daily necessities, making, storing
and serving of food, cleaning the house, working with those helping with domestic duties such as maids, cooks etc.,
looking after possessions and valuable in the house.
Students - Assess a score on performance in school/college, regularity, discipline, interest in future studies, behaviour at
the educational institution. Those who had to discontinue education on account of mental disability and unable to
continue further should be given a score of 4.
IDEAS SCORING SHEET
ITEMS 0 1 2 3 4
Self care
Interpersonal Activities
Work
A. TOTAL SCORE
B. DOI SCORE.
Appendix V
[see paragraph 31]
Screening tests for screening for carriers of haemoglobinopathies for sickle cell cases
NESTROFT Test (Naked Eye Single Tube Red cell Osmotic Fragility Test)
DCIP test (Di-Chlorophenol-Indo-Phenol) Solubility Test
NESTROFT TEST
Nestroft Test: For Beta thalassemia trait, this test has a high specificity and sensitivity and is easy to perform. The
positive test has to be followed by a confirmatory test Sensitivity of 91-100%, specificity of 85.47%. Positive predictive
value of 66% and negative predictive value of 97- 100%.
Screening protocols for Hemoglobinopathies in community settings and public health facilities Initial screening (1
and 2)
Test tube based Turbidity tests in Community settings (one or more tube tests may be included depending on
prevalence)
116 THE GAZETTE OF INDIA : EXTRAORDINARY [PART II—SEC. 3(ii)]
NESTROFT (For Thalassemia major)
SOLUBILITY TEST (For HbS)
Appendix VI
[see paragraph 37.4]
Test Name Description
Estimation of Hemoglobin in gm % by digital Hemoglobinometer using a finger prick sample in field / screening point
(school).
NESTROFT Naked Eye Single Tube Red cell Osmotic Fragility Test in a single tube with a saline concentration of
0.36%. Can be done on finger -prick sample as screening test for selecting samples for Hb HPLC for detection of β
Thalassemia Trait - CBC Complete Blood Counts are obtained by an automated Blood Cell Counter. Used for
determination of Hb level and for RBC parameters (RBC, MCV, MCH, MCHC and RDW) for evaluation of type of
anemia. MCV and MCH are the most important indices in diagnosis of thalassemiaPS or GBP Microscopic examination
of a stained peripheral blood smear (PS) on a glass slide provides a General Blood Picture. Required to evaluate cases
mainly of severe anemia and moderate anemia. GBP in thalassemia major and severe TI is quite characteristic and highly
supportive of diagnosis.
Reticulocyte count - Reticulocytes (or Retics) are young RBCs identified by staining by supravital stains like New
Methylene Blue. They are usually found to be increased in hemolytic anemias when there is destruction of normal
population of RBCs. G6PD enzyme levels are normal in young RBCs even in G6PD deficiency thus a falsely normal or
high level of G6PD enzyme may be obtained if test done after clinical symptoms have appeared
Solubility test is used as a simple low cost screening test for sickle cell Hemoglobin (HbS) based on the property of
insolubility of HbS in a high molarity phosphate buffer solution forming tactoids (water crystals) producing turbid
solution. It does not distinguish between heterozygous or homozygous states. HbD and HbG showing similar mobility as
HbS on electrophoresis are soluble. False positives are common due to polycythemia and other abnormal hemoglobins
and high HbF may result in a ‘false negative’ test thus should be used only as a screening test. The test is unreliable upto
6 months of age due to high HbF and thus cannot be used for newborn screening
Sickling Test It is a simple functional test for distinguishing Hb S disorders- HbSS; HbS/E; HbS /β0thal, HbS/ β+thal;
HbS/HbD; from other variants having same mobility as HbS.The test is based on ‘sickling’ of RBCs in reduced
oxygenation. There are some other rare variants other than HbS that also produce sickling.
Serum Ferritin by ELISA
At some stage of the diagnostic protocol, it may become important to determine iron status to arrive at diagnosis. It may
be necessary to exclude iron deficiency and in carriers of thalassemia and variant hemoglobins or to establish coexistent
iron deficiency that may alter hematologic parameters. Normal or increased iron are found in thalassemia. Quantitative
assay of serum Ferritin is a cost effective method for establishing iron deficiency.
Hb HPLC The test based on automated High Performance Liquid Chromatography of Hemoglobin to separate different
hemoglobin fractions is used for detection ofThalassemia and common hemoglobinopathies.
¹Hkkx IIµ[k.M 3(ii)º Hkkjr dk jkti=k % vlk/kj.k 117
Appendix VII
[ see paragraph 39.4.]
Diagnosis of hemophilia
The majority of patients with hemophilia have a known family history of the condition. However, about one-third of
cases occur in the absence of a known family history. Most of these cases without a family history arise due to a
spontaneous mutation in the affected gene. Other cases may be due to the affected gene being passed through a long line
of female carriers.
If there is no known family history of hemophilia, a series of blood tests can identify which part or protein factor of the
blood clotting mechanism is defective if an individual has abnormal bleeding episodes.
Screening Tests
Screening tests are blood tests that show if the blood is clotting properly. Types of screening tests:
The complete blood count in particular the platelet count and bleeding time test should be measured as well as two
indices of blood clotting, the prothrombin time (PT) and activated partial thromboplastin time (aPTT). A normal platelet
count, normal PT, and a prolonged aPTT are characteristic of hemophilia A and hemophilia B.
Complete Blood Count (CBC)
This common test measures the amount of hemoglobin , the size and number of red blood cells and numbers of different
types of white blood cells and platelets found in blood. The CBC is normal in people with hemophilia. However, if a
person with hemophilia has unusually heavy bleeding or bleeds for a long time, the hemoglobin and the red blood cell
count can be low.
Activated Partial Thromboplastin Time (APTT) Test
This test measures how long it takes for blood to clot. It measures the clotting ability of factors VIII (8), IX (9), XI (11),
and XII (12). If any of these clotting factors are too low, it takes longer than normal for the blood to clot. The results of
this test will show a longer clotting time among people with hemophilia A or B. in this process of coagulation is
stimulated by contact kaolin or collagen or ellagic acid. Normal value ie 30-32 seconds and are cheap and available at
most of places
Prothrombin Time (PT) Test
This test also measures the time it takes for blood to clot. It measures primarily the clotting ability of factors I (1), II (2),
V (5), VII (7), and X (10). If any of these factors are too low, it takes longer than normal for the blood to clot. The results
of this test will be normal among most people with hemophilia A and B.
Note these tests are simple, easy to perform and act as screening tests and are available at most of places
Specific tests (factor assay) for the blood clotting factors can then be performed to measure factor VIII or factor IX levels
and confirm the diagnosis. Factor assays are required to diagnose and confirm a bleeding disorder. This blood test
shows the type of hemophilia and the severity. It is important to know the type and severity in order to create the best
treatment plan.
I. Factor VIII is the protein which is lacking in hemophilia A.
II. Factor IX is the protein which is lacking in hemophilia B.
[No. 16-09/2014-DD-III]
SHAKUNTALA DOLEY GAMLIN, Secy.
Uploaded by Dte. of Printing at Government of India Press, Ring Road, Mayapuri, New Delhi-110064
and Published by the Controller of Publications, Delhi-110054.