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PENTAX i-SCAN™ with Anal Cancer


Case Study
For Medical Professionals

Patient History Patient Follow-up and


A 69-year-old male was referred for Outcome:
routine surveillance colonoscopy. He The patient subsequently underwent
denied any symptoms of bright red R-US (Rectal Endoscopic Ultrasound)
blood per rectum or any rectal pain which revealed a 1.4 cm x 2.1cm
or discharge. His family history was lesion in the distal anorectum c/w
positive with his father having being Figure 1
anal cancer stage: T2N0. He was then
diagnosed with colorectal cancer at referred to combined multi-disciplinary
age 78 years. The patient had one colo-rectal surgery and oncology clinic
prior colonoscopy 5 years earlier that and under went therapy with chemo/
demonstrated a small tubular adenoma. radiation with successful response.

Colonoscopy Findings:
A small sessile polyp was found in
Figure 2.1
the sigmoid colon and was removed
with “Cold” snare polypectomy. The
pathology was consistent with a
tubular adenoma.

Retroflexion exam in the rectum


Deepak V. Gopal,
appeared normal. However, in the MD, FRCP(C), AGAF, FACG, FASGE
forward view as the colonoscope Professor of Medicine
Figure 2.2
was withdrawn, in the anorectum, Director of Endoscopy,
Division of Gastroenterology
just at the dentate line, colonoscopy Univeristy of Wisconsin -
with white light endoscopy (WLE) School of Medicine & Public Health
suggested mucosal irregularity Madison, WI United States
(Figure 1). The i-SCAN 1 mode was
switched on and revealed a small
erythematous, friable, ulcerated
Pathology contribution:
nodular lesion in the distal ano-rectum Figure 2.3
Rashmi Agni, MD
in the posterior wall (Figure 2.1, 2.2, Associate Professor of Medicine
2.3). This area was targeted for biopsy Department of Pathology &
and the histopathology revealed Laboratory Medicine
Univeristy of Wisconsin -
squamous cell cancer of the anal canal School of Medicine & Public Health
(Figure 3 pathology). Madison, WI United States

Figure 3

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