Hormonal Control of Human Reproduction: Female: Hormone Source Function

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Hormonal Control of Human Reproduction: Female

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The Ovarian and Menstrual Cycle
 Ovarian Cycle – governs the preparation of endocrine tissues and release of eggs
 Menstrual Cycle – governs the preparation and maintenance of the uterine lining
 These cycles occur concurrently and are coordinated over a 22-32 day cycle, with an average length of 28 days
Hormones Involved
Hormone Source Function
Gonadotropin- hypothalamus produced and sent to the anterior pituitary when
releasing hormone reproductive hormones are required
(GnRH)
Follicle Stimulating anterior pituitary stimulates the development of the egg cells called ova from
Hormone (FSH) gland the follicles
Luteinizing Hormone anterior pituitary plays a role in the development of ova, induction of
(LH) gland ovulation and stimulation of estradiol and progesterone
Estrogen Ovaries reproductive hormone in females assists in endometrial
regrowth, ovulation and calcium absorption; responsible for
the secondary characteristics of females.
Estradiol During follicular phase one of the four types of estrogen being produced; works
and ovulation: follicle with progesterone.
During luteal phase:
corpus luteum
Progesterone Corpus luteum maintains the endometrium to help in ensuring pregnancy
and inhibits FSH and LH release
Inhibin Follicle Cells inhibits FSH production, LH also plays a role in the
development of the ova, induction of ovulation and
stimulation of estradiol and progesterone production by
the ovaries.

Effects of Hormones in each Phase


PHASES
Follicular Phase
Effects of Hormones Ovulation Luteal Phase
(First half of the ovarian
(14th Day) (15th-28th Day)
cycle)
Pituitary Hormones LH and FSH stimulate LH and FSH stimulate maturaion LH stimulates growth of a
several follicles to grow. of one of the growing follicles. corpus luteum from
( Luteinizing Hormone follicular tissue left behind
[LH] and Follicle after the ovulation
Stimulating Hormone
[FSH])
Ovarian Hormones Follicles produce low Growing follicles begin to The corpus luteum secretes
levels of estradiol that: produce high level of estradiol estradiol and progesterone
(Estradiol and 1. Inhibit GnRH secretion which that
Progesterone) by the hypothalamus
keeping LH and FSH 1. Stimulate GnRH secretion by 1. Block GnRH production
Levels low the hypothalamus. LH and FSH by the hypothalamus and
2. Cause the endometrial Levels rise, resulting in ovulation LH and FSH production by
arteries to constrict about a day later the pituitary
resulting in menstruation
2. Cause the endometrium to 2. Cause the endometrium
thicken. to further develop

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