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    Statin Dose Intensity and Equivalency Chart (UMHS 2014) PDF

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    MavisVermilion
    This table provides information on statin dose intensity and equivalency. It lists several statins and their doses that achieve high-intensity therapy with a 50% or greater reduction in LDL-C, moderate-intensity therapy with a 30-50% reduction, and low-intensity therapy with less than a 30% reduction. The table also includes the estimated cost per month of treatment with each statin and dose. Shading is used to distinguish between doses that achieve high versus moderate intensity based on published treatment guidelines.

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    Statin Dose Intensity and Equivalency Chart (UMHS 2014) PDF

    Uploaded by

    MavisVermilion
    3K views1 page
    This table provides information on statin dose intensity and equivalency. It lists several statins and their doses that achieve high-intensity therapy with a 50% or greater reduction in LDL-C, moderate-intensity therapy with a 30-50% reduction, and low-intensity therapy with less than a 30% reduction. The table also includes the estimated cost per month of treatment with each statin and dose. Shading is used to distinguish between doses that achieve high versus moderate intensity based on published treatment guidelines.

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    This table provides information on statin dose intensity and equivalency. It lists several statins and their doses that achieve high-intensity therapy with a 50% or greater reduction in LDL-C, moderate-intensity therapy with a 30-50% reduction, and low-intensity therapy with less than a 30% reduction. The table also includes the estimated cost per month of treatment with each statin and dose. Shading is used to distinguish between doses that achieve high versus moderate intensity based on published treatment guidelines.

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    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    3K views1 page

    Statin Dose Intensity and Equivalency Chart (UMHS 2014) PDF

    Uploaded by

    MavisVermilion
    This table provides information on statin dose intensity and equivalency. It lists several statins and their doses that achieve high-intensity therapy with a 50% or greater reduction in LDL-C, moderate-intensity therapy with a 30-50% reduction, and low-intensity therapy with less than a 30% reduction. The table also includes the estimated cost per month of treatment with each statin and dose. Shading is used to distinguish between doses that achieve high versus moderate intensity based on published treatment guidelines.

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    Table 5.

    Statin Dose Intensity and Equivalency Chart*

    Statin %LDL-C HMG-CoA Reductase Inhibitor


    Intensity Reduction Rosuvastatin Atorvastatin Pitavastatin Simvastatin Lovastatin Pravastatin Fluvastatin
    63
    62
    61 40 mg
    High- ($196)
    60
    Intensity
    59
    (lowers
    58 80mg
    LDL-C ≥
    56 20 mg ($9 gen, $236 br)
    50%)
    54 ($196)
    52
    50 10 mg
    48 ($196) 40mg
    46 ($9 gen, $236 br)
    44
    42 20mg
    Moderate- 40 ($9 gen, $236 br)
    40 mg
    Intensity 38 4 mg
    ($4 g, $202 br)
    (lowers 36 ($81) 80 mg
    LDL-C 30% 80mg ($25 g, 173
    to < 50%) 34
    ($4 gen, br)
    20 mg
    $306 br) 40 mg
    2 mg ($4 g, $202 br)
    32 ($25gen, 173 80mg
    ($81)
    5 mg br) ($95 gen,
    30 ($196) 40mg $300 br)
    10mg 10 mg
    ($4 gen,
    28 ($7 gen, $165 br) ($4 g, $116 br) 20mg
    $153)
    Low- 26 ($17 gen,
    20 mg 117 br)
    Intensity 24 1 mg 40mg
    ($4 gen,
    (lowers ($81) ($95 gen, 150
    22 5 mg $43 br)
    LDL-C < br)
    ($4 g, $82 br)
    30%) 20 10 mg 10mg 20mg
    ($4 gen, ($19 gen, 58 ($95 gen, 150
    18
    $43 br) br ) br)

    Note: The shading reflects doses listed in the ACC/AHA Guideline on Treatment of Blood Cholesterol (2013) as reflecting high-intensity therapy (≥ 50%
    reduction in LDL-C, darker shading) and moderate-intensity therapy (30% to 50% reduction in LDL-C, lighter shading).
    *In one trial atorvastatin 40 mg was used for down-titration if unable to tolerate 80 mg.

    UMHS Lipid Therapy Guideline, May 2014

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