Research On Anabolic Steroids
Research On Anabolic Steroids
Research On Anabolic Steroids
Photo by NIDA
Health care providers can prescribe steroids to treat hormonal issues, such as delayed
puberty. Steroids can also treat diseases that cause muscle loss, such as cancer and
AIDS. But some athletes and bodybuilders misuse these drugs in an attempt to boost
performance or improve their physical appearance.
The majority of people who misuse steroids are male weightlifters in their 20s or 30s.
Anabolic steroid misuse is much less common in women. It is difficult to measure
steroid misuse in the United States because many national surveys do not measure it.
However, use among teens is generally minimal. The 2016 NIDA-funded Monitoring the
Future study has shown that past-year misuse of steroids has declined among 8th and
10th graders in recent years, while holding steady for 12th graders.
cycling—taking multiple doses for a period of time, stopping for a time, and then
restarting
There is no scientific evidence that any of these practices reduce the harmful medical
consequences of these drugs.
Anabolic steroids work differently from other drugs of abuse; they do not have the
same short-term effects on the brain. The most important difference is that steroids do
not directly activate the reward system to cause a “high”; they also do not trigger rapid
increases in the brain chemical dopamine, which reinforces most other types of drug
taking behavior.
Misuse of anabolic steroids might lead to negative mental effects, such as:
mania
People who inject steroids increase their risk of contracting or transmitting HIV/AIDS or hepatitis.
Aside from mental effects, steroid use commonly causes severe acne. It also causes the
body to swell, especially in the hands and feet.
Long-Term Effects
Anabolic steroid misuse might lead to serious, even permanent, health problems such
as:
enlarged heart, high blood pressure, and changes in blood cholesterol, all of which
increase the risk of stroke and heart attack, even in young people
In men:
shrinking testicles
baldness
development of breasts
In women:
male-pattern baldness
enlarged clitoris
deepened voice
In teens:
stunted growth (when high hormone levels from steroids signal to the body to stop bone growth too
early)
stunted height (if teens use steroids before their growth spurt)
Some of these physical changes, such as shrinking sex organs in men, can add to
mental side effects such as mood disorders.
Are anabolic steroids addictive?
Even though anabolic steroids do not cause the same high as other drugs, they can
lead to a substance use disorder. A substance use disorder occurs when a person
continues to misuse steroids, even though there are serious consequences for doing so.
The most severe form of a substance use disorder is addiction. People might continue
to misuse steroids despite physical problems, high costs to buy the drugs, and negative
effects on their relationships. These behaviors reflect steroids' addictive potential.
Research has further found that some steroid users turn to other drugs, such as
opioids, to reduce sleep problems and irritability caused by steroids.
People who misuse steroids might experience withdrawal symptoms when they stop
use, including:
fatigue
restlessness
loss of appetite
sleep problems
steroid cravings
One of the more serious withdrawal symptoms is depression, which can sometimes lead
to suicide attempts.
Points to Remember
Anabolic steroids are synthetic variations of the male sex hormone testosterone.
Health care providers can prescribe steroids to treat various medical conditions. But some athletes and
bodybuilders misuse these drugs to boost performance or improve their physical appearance.
People who abuse anabolic steroids usually take them orally, inject them into the muscles, or apply them
to the skin with a cream or gel.
Misuse of anabolic steroids might lead to short-term effects, including paranoid jealousy, extreme
irritability and aggression, delusions, impaired judgement, and mania.
Continued steroid misuse can act on some of the same brain pathways and chemicals that are affected by
other drugs, including dopamine, serotonin, and opioid systems.
Anabolic steroid misuse might lead to serious long-term, even permanent, health problems.
People who inject steroids increase their risk of contracting or transmitting HIV/AIDS or hepatitis.
Even though anabolic steroids do not cause the same high as other drugs, they can lead to addiction.
Some people seeking treatment for anabolic steroid addiction have found behavioral therapy and
medications to be helpful. Medicines can help treat symptoms of withdrawal in some cases.