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    Source and Effect of Impurities in Pharmaceuticals

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    Mompati Letsweletse
    This document discusses the sources and effects of impurities in pharmaceuticals. It identifies the main sources of impurities as raw materials, manufacturing processes, storage conditions, and decomposition. Impurities can cause incompatibilities, lower shelf life, difficulties in formulation and use, changes to physical and chemical properties, decreased therapeutic effects, toxicity over time, and changes to odor, color and taste if limits are exceeded. Tests are conducted to limit impurities and make pharmaceuticals safer.

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    Source and Effect of Impurities in Pharmaceuticals

    Uploaded by

    Mompati Letsweletse
    130 views1 page
    This document discusses the sources and effects of impurities in pharmaceuticals. It identifies the main sources of impurities as raw materials, manufacturing processes, storage conditions, and decomposition. Impurities can cause incompatibilities, lower shelf life, difficulties in formulation and use, changes to physical and chemical properties, decreased therapeutic effects, toxicity over time, and changes to odor, color and taste if limits are exceeded. Tests are conducted to limit impurities and make pharmaceuticals safer.

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    pharmaceutical impuritties

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    This document discusses the sources and effects of impurities in pharmaceuticals. It identifies the main sources of impurities as raw materials, manufacturing processes, storage conditions, and decomposition. Impurities can cause incompatibilities, lower shelf life, difficulties in formulation and use, changes to physical and chemical properties, decreased therapeutic effects, toxicity over time, and changes to odor, color and taste if limits are exceeded. Tests are conducted to limit impurities and make pharmaceuticals safer.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    130 views1 page

    Source and Effect of Impurities in Pharmaceuticals

    Uploaded by

    Mompati Letsweletse
    This document discusses the sources and effects of impurities in pharmaceuticals. It identifies the main sources of impurities as raw materials, manufacturing processes, storage conditions, and decomposition. Impurities can cause incompatibilities, lower shelf life, difficulties in formulation and use, changes to physical and chemical properties, decreased therapeutic effects, toxicity over time, and changes to odor, color and taste if limits are exceeded. Tests are conducted to limit impurities and make pharmaceuticals safer.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    of 1

    Source and effect of Impurities in Pharmaceuticals

    We know that the substance that are used in pharmaceutical field must be pure so
    that they can be used safely. But it is very difficult to obtain an almost pure
    substance. We find different substance and chemicals with varying degree of purity.
    So today we are going to discuss different sources of impurities and some of the
    effect of impurities on pharmaceuticals.

    Sources of impurities.

     Raw materials employed in manufacture.


     Method or the process used in manufacture.
     Chemical processes and the plant materials employed in the processes.
     Storage conditions.
     Decomposition.
    Effect of Impurities: We know that almost pure substances are difficult to get and
    some amount of impurity is always present in the material. So the impurities which
    are present in the substances may have the following effects.

     Impurities may bring about incompatibility with other substances.


     Impurities may lower the shelf life of the substances.
     Impurities may cause difficulties during formulations and use of the
    substances.
     Sometimes Impurities changes the physical and chemical properties of the
    substances.
     Therapeutic effect can be decreased.
     Shows toxic effect after a certain period.
     Injurious when present above certain limits.
     It may change odour, colour, taste of the substance.
    To prevent these impurities many test such as limit test are carried out to lower the
    impurities to make the pharmaceuticals more safe.

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